• 한국자원식물학회지
• /
• 제18권1호
• /
• pp.64-70
• /
• 2005

부존자원의 최대생산과 농경지 활용 극대화를 위해 패모에 참깨, 들깨, 열무, 홍화 등 간작물을 도입하여 2001년부터 2003년까지 3년에 걸쳐 시험한 바, 패모의 간작물로 도입 된 홍화, 들깨, 참깨, 열무 등은 패모 생육에 지장 없이 재배가 가능하였으며, 작부 유형에 따른 패모의 지상부 생육은 차이가 미미하였으나, 지하부 수량은 단작에서 많았다. 소득은 패모 단작에 비하여 패모+열무와 패모+홍화+들깨의 작부유형에서 각각 $45\%$, $35\%$ 증대되었다.

• 대한한의학방제학회지
• /
• 제18권2호
• /
• pp.109-124
• /
• 2010

In this study, we considered the usecase of formulas containing either Fritillaria Bulb (川貝母) or Fritillaria Thunbergii Bulb (浙貝母). These two medicinal materials are distinguished in the Korea Pharmacopoeia and circulating the market separately. But only term "貝母" is traditionally written for describing formulas, and the proper material will have to be determined by a subjective point of view. So, we have comparatively studied the nature, flavor, meridian entry, effect and indication of two materials first. Then we have chosen 54 formulas that "貝母" was used as a primary material from the Donguibogam and the Bangyachappyun, and we have compared effects, indications of two materials and indication of 54 formulas. Finally, we have suggested proper materials for each formula by referring the results above and sentences, which is explaining formulas and the roles of materials in the combination for treatment. The analysis showed that Fritillaria Bulb is proper to 15 formulas, Fritillaria Thunbergii Bulb is proper to 31 ones. This number is 85.2% of 54 formulas and this result shows that we need to distinguish between two materials for "貝母" in the formulas from old traditional literature. For the rest 8 formulas (14.8%), we could not analyze which material is proper or not.

• The Plant Pathology Journal
• /
• 제38권5호
• /
• pp.533-540
• /
• 2022

Thunberg fritillary (Fritillaria thunbergii), a perennial used in traditional Chinese herbal medicine, is a members of the family Liliaceae. The degeneration of germplasm is a severe problem in the production of Fritillaria thunbergii var. chekiangensis. However, no information about viral infections of F. thunbergii var. chekiangensis has been reported. In this study, we sequenced the small RNAs of F. thunbergii var. chekiangensis from leaves and bulbs, and viruses were identified using a phylogenetic analysis and BLAST search for sequence. In addition, multiplex reverse transcriptase-polymerase chain reaction (RT-PCR) was used to rapidly detect viruses in this variety. Our study first reported that five viruses infected F. thunbergii var. chekiangensis. Among them, fritillary virus Y (FVY), lily mottle virus (LMoV), Thunberg fritillary mosaic virus (TFMV), and hop yellow virus (HYV) had been reported in F. thunbergii, while apple stem grooving virus was first reported in the genus Fritillaria. A multiplex RT-PCR method was developed to rapidly test the four viruses FVY, LMoV, TFMV, and HYV in F. thunbergii var. chekiangensis. Our results provide a better understanding of the infection of F. thunbergii var. chekiangensis by viruses and a basic reference for the better design of suitable control measures.

• 한국약용작물학회지
• /
• 제7권2호
• /
• pp.129-137
• /
• 1999

Fritillaria pallidiflora의 전분체 미세구조와 신구인경의 세포간 대사물질의 이동을 전자현미경으로 관찰하였다. 기존의 인경과 새로 형성된 인경세포내 전분체는 내부 막구조에 있어서 뚜렷한 차이를 나타내었을 뿐만 아니라 대사물질의 세포간 이동도 활발히 이루어지고 있음을 관찰할 수 있었다. 엔도사이토시스와 엑소사이토시스 현상이 세포막에서 관찰되었으며 대사물질의 세포간 이동을 위해 원형질 연락에 있어서 염류수송 경로가 형성됨을 알 수 있었다. 또한 일단의 소포체들이 원형질 연락의 말단에 위치하고 있었는데 이는 세포간 물질 이동에 이들이 관여하고 있음을 알 수 있었다. 이러한 결과는 F. pallidiflora의 신구 인경형성과 발달에 미치는 기작을 연구하는데 유용하게 이용될 수 있는 것으로 생각된다.

• 한국자원식물학회지
• /
• 제24권6호
• /
• pp.729-732
• /
• 2011

This experiment was conducted to clarify the antitussive effect of Fritillaria unibracteata Hsiao et K. C. Hsia. The antitussive effect in ethanol (75, 50, 30%) extracts from F. unibracteata was relatively high. The ethanol extracts of 20, 40 mg/kg concentrations were especially good antitussive effect. The ethanol extracts of F. unibracteata showed lower antitussive activities of 20~30% than sodium chloride injection used as a blank space control.

• Mycobiology
• /
• 제41권4호
• /
• pp.183-190
• /
• 2013

Amanita Pers. is a well-known monophyletic mushroom genus with a broad distribution. However, the diversity of Korean Amanita species has been underestimated, and most taxonomic studies conducted in Korea have only investigated their morphological characteristics. This approach is frequently insufficient for correct identification in fungal classification; therefore, we constructed a phylogeny of Amanita subgen. Lepidella in order to understand the phylogenetic placements of 16 Amanita specimens collected in Korea in 2012. The phylogeny constructed using the sequence data of the internal transcribed spacers and the partial large subunit of ribosomal RNA identified nine Amanita species (A. citrina, A. excelsa var. spissa, A. flavipes, A. fritillaria, A. oberwinklerana, A. pallidorosea, A. rubescens, A. subjunquillea, and A. volvata); of these, A. fritillaria, A. oberwinklerana, and A. pallidorosea are new to Korea.

• 대한본초학회지
• /
• 제29권6호
• /
• pp.133-140
• /
• 2014

Objectives : Paemo is a phlegm-resolving drug with cold properties and classified 5 kinds which come from 11 species of original plant. All the more, according to literature record, 20 species of original plant were used. As a natural result, these are easily to confuse and there are a lot of counterfeit product. So we are to present a differential standard of Paemo. Methods : It was planed a differential standard form through outer appearance of the original plant and outer appearance in the form of each medicines which was collected local market or field for 11 species which is listed in Korea or China pharmacopeia. Results : It was possible to distinguish the orignal plant between Fritillaria and Bolbostemma through its stem shape. In Fritillaria of original plant, it was possible to distinguish through its width of leaf, number of leafy bracts, color and position of flower and shape of leaf apex. In outer appearance in the form of each medicines, there are difference in color and texture of medicine between Fritillaria and Bolbostemma and there are difference in size, shape, size of inner and outter fleshy leaf of bulb, pattern of surface and apex of fleshy leaf of bulb among 10 Fritillaria species. Conclusions : This study presents various differences in the outer appearance of the original plant and the outer appearance in the form of each medicines among Paemo. It will be helpful to further applied research.

• 동의생리병리학회지
• /
• 제25권3호
• /
• pp.510-515
• /
• 2011

This study was conducted to evaluate the depigmenting properties of ethanol extract from a Fritillaria verticillata Willd. (EFV) in B16F10 cells. Fritillaria verticillata Willd., a perennial herbaceous plant, has been used as a stimulator of mammary gland, expectorant, blood pressure depressant, antitussive agents in Korean herbal medicine. In the present study, we observed that melanin synthesis of B16F10 cells were significantly decreased by EFV without cytotoxicity. However, EFV could not suppress tyrosinase activity in B16F10 cells and mushroom tyrosinase activity. Furthermore, EFV did not effect the protein expression of tyrosinase, tyrosinase-related protein -1 (TRP-1), and TRP-2. These results suggest that EFV inhibited melanin synthesis and the hypopigmentary effect of EVF was not due to regulation of tyrosinase protein.

• 대한한의학방제학회지
• /
• 제16권1호
• /
• pp.79-94
• /
• 2008

Although inflammatory mediators such as nitric oxide(NO) and pro-inflammatory cytokines are involved in host defense mechanism, these overproduction contributes to the pathogenesis of several diseases such as otitis media, hearing loss, periodontitis, bacterial sepsis, rheumatoid arthritis, chronic inflammation and autoimmune diseases. We investigate the anti-inflammatory effects of water extract from Ji-Pae-San(JPSWE) fomulated with Angelica dahurica plus Fritillaria Verticillata, Angelica dahurica(ADWE), and Fritillaria Verticillata(FUVE) in vitro and in vivo. Each extract inhibited the production of inflammatory mediators(NO, $IL-1{\beta}$, IL-6, $TNF-{\alpha}$, and prostaglandin $E_2$) and the expression of inducible NO synthase(iNOS) and cyclooxygenase-2(COX-2) in lipopolysaccharide(LPS)-stimulated RAW 264.7 macrophages in a dose-dependent manner. These inhibitory effects were synergistically increased by their combination. JPSWE also inhibited $TNF-{\alpha}$, $IL-1{\beta}$, IL-6. and $PGE_2$ production as well as COX activity in LPS-stimulated mice. Moreover, JPSWE significantly suppressed death by LPS-septic shock in mice(survival rate: 100%). These results suggest that Ji-Pae-San may be useful for therapeutic drugs against inflammatory immune diseases, probably by suppressing the production of inflammatory mediators.

• 한국균학회지
• /
• 제48권3호
• /
• pp.251-271
• /
• 2020

Diversity and community composition of bulb-associated fungi of Fritillaria Cirrhosae Bulbus source plants, which are used in traditional chinese medicine, in the eastern Himalaya-Hengduan Mountains, southwestern China, were estimated based on the internal transcribed spacer rDNA sequence analysis, using host plant species, geographic area, and plant phenology as variables. A total of 1,486 fungal sequences assigned to 251 operational taxonomical units (OTUs) were obtained from the bulbs. Fungal OTUs comprised 96.41% Ascomycotina, 3.52% Basidiomycotina, and 0.07% Zygomycotina. Sordariomycetes, Hypocreales, and Nectriaceae were the most frequent fungal lineages at each taxonomic rank. Fusarium, Ilyonectria, Tetracladium, Leptodontidium, and Tomentella were the top OTU-rich genera. Fusarium sp. 03, Ilyonectria rufa, Fusarium sp. 08, Ilyonectria sp. 03, and Leptodontidium orchidicola 03 represented the most frequent OTUs. Fusarium spp. were the most frequent general taxa. The distribution of fungal community exhibited preferences for host plant species, geographic area, and plant phenology. These findings are the foundation of our research on culturing and active metabolites of bulb-associated fungi of Fritillaria Cirrhosae Bulbus source plants.