• Clinical and Experimental Reproductive Medicine
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• 제49권3호
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• pp.185-195
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• 2022

Objective: This study aimed to determine the effect of sperm DNA fragmentation (SDF) on the cumulative live birth rate (CLBR) in intracytoplasmic sperm injection (ICSI) cycles in couples with unexplained infertility. Methods: We conducted a prospective study of 145 couples who underwent ICSI cycles for unexplained infertility. Based on the SDF rate, patients were categorized into a low SDF group (SDF ≤30%, n=97) and a high SDF group (SDF >30%, n=48). SDF was assessed using the acridine orange test on density gradient centrifugation prepared samples. The CLBR was calculated as the first live birth event per woman per egg collection over 2 years. Results: The high SDF group (SDF >30%) showed a significantly lower CLBR (p<0.05) and a significantly higher miscarriage rate (p<0.05) than the low SDF group (SDF ≤30%). No significant difference was observed in the implantation and cumulative pregnancy rates between the two SDF groups. The total number of embryo transfers was stratified further into fresh and frozen embryo transfers. In the fresh embryo transfers, there were significant differences in the implantation rates, clinical pregnancy rates, and live birth rates (p<0.05) between the low SDF and high SDF groups. However, in the frozen embryo transfers, there were no significant differences in clinical outcomes between the two groups. In the multivariable logistic regression analysis, SDF was a predictor of CLBR (p<0.05) when adjusted for possible confounding factors. Conclusion: High SDF was associated with a lower CLBR and a higher miscarriage rate in the ICSI cycles of couples with unexplained infertility.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2021년도 춘계학술대회
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• pp.496-498
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• 2021

우리나라는 1980년 이전 높은 출산율을 기반으로 총인구는 지속적으로 증가하여 왔으며, 1980년대 중반 이후 출산율은 급격하게 떨어지면서 인구대체 수준 이하까지 떨어지게 되었다. 지역 내 저출산의 원인은 자발적 거부라기보다는 지역 사회 구조적인 원인을 다각적으로 파악하여 원인을 찾아내는 것이 필요하다. 여러 지역 중 출산율이 매우 낮은 예산 지역을 기준으로 지역 인터넷 뉴스 및 산모들이 많이 참여하는 지역 대표 카페 데이터를 수집하였다. 인구감소, 저출산, 육아 복지 등에 관하여 이슈화 되었던 동시출현단어의 빈도를 분석하여 출산 저해 원인을 분석하였다.

• Child Health Nursing Research
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• 제10권1호
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• pp.5-13
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• 2004

Purpose: The aim of this study was to analyze the correlation of gestational age and birth weight with weight gain of very low birth weight infants(VLBWI) during their hospital stay. Method: This is a 5 year retrospective study of which data were collected through review of medical records. Subjects were 124 VLBW infants with a birth weight more than 1000g and less than 1500g who received neonatal intensive care at the university hospital between January 1, 1997 to December 31, 2001. Result: After calculating the z scores of birth weights and discharge weights, z scores of discharge weight and birth weight were compared with the median weight of a fetus of comparable gestational age based on an intrauterine growth reference. There was a significant difference between z scores of birth weight and discharge weight(t=11.60, df=122, p=0.000). Regardless of intensive care during the prolonged hospital stay, VLBW infants showed slow growth rate compared with the median weight of a fetus of comparable gestational age. Conclusion: VLBW infants developed a poor velocity of weight gain during the prolonged hospital stay after birth. The development worsened during the period of physiological weight loss and regain, and they did not reach to comparable growth rate of normal fetus even at the time of discharge. This poor growth velocity of VLBW infants influence negatively for their future growth. Therefore nureses who work at the neonatal intensive care unit must develop an effective nursing intervention protocol to promote the velocity of weight gain and to conduct the parental educational sessions to emphasize the importance of weight gain for VLBW infants at home.

• 가족자원경영과 정책
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• 제17권4호
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• pp.127-144
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• 2013

The low birth rate in Korea reflects the declining desire to have children in this country due to rising emphasis on personal lifestyle. Since this phenomenon has accelerated, boosting the birth rate has become one of the most important policy tasks in Korea. The purpose of this research was to perform a case study based on women's lived experience to understand how the childbirth encouragement policy promoted by the government in order to boost the birth rate has affected the perception of childbirth among women. The findings are as follows : First, the effect of the childbirth encouragement policy on women's perceptions has been fairly low. Second, the social environment for encouraging childbirth is inadequate. Third, the economic burdens associated with childbirth and child care are still significant. Finally, the impact of the childbirth encouragement policy on changes in the perceptions of childbirth has been minimal. Based on these findings, various motivations for changes in the perceptions of childbirth among women were identified, leading to the following conclusion: Establishing a long-term childbirth encouragement policy is an effective way to boost the childbirth rate.

• Neonatal Medicine
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• 제25권1호
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• pp.29-36
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• 2018

Purpose: The purpose of this study was to investigate the outcome after changes in the treatment strategies for very low birth weight infant (VLBWI) in a single neonatal intensive care unit (NICU) center. Methods: We performed a retrospective review of 300 VLBWI born from 1st January 2010 to 31th December 2016. We compared the outcomes including survival rate, birth weight (BW), gestational age (GA), and morbidities between period I (2010-2013, P-I) and period II (2014-2016, P-II). Results: The average survival rate was not different between P-I and P-II. However, the survival rate of ${\leq}24$ weeks' GA, 25 weeks' GA, 26 weeks' GA were 57%, 69%, 93% respectively in P-II and 31%, 59%, 87% in P-I respectively. The survival rate of infants with birth weight <500 g, 500-749 g, 750-999 g were 100%, 55%, 90% respectively in P- II and 50%, 24%, 80%, respectively in P-I. The incidence of bronchopulmonary dysplasia (BPD) was higher in P-II than in P-I (P=0.012) and moderate-to-severe BPD was also higher in P-II (P=0.004). Incidence of patent ductus arteriosus (PDA) with treatment, necrotizing enterocolitis (stage ${\geq}2$), and abnormal brain sonography were significantly lower in P-II (P=0.027, P=0.032, P=0.005). Incidences of retinopathy of prematurity (ROP) with laser treatment and early sepsis were not different. Conclusion: The survival rate and complications of VLBWI were improved in period II, especially in less than 750 g and below 26 weeks, except incidence of BPD. Changes of NICU strategies were effective to improve mortality and morbidity in VLBWI.

• 한국인구학
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• 제34권3호
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• pp.179-209
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• 2011

본 연구는 한국보건사회연구원의 "2009년도 전국 결혼 및 출산 동향 조사" 패널자료를 활용하여 20~44세에 이르는 2,678명의 미혼 남녀(남 1,425명, 여 1,253명)가 생각하는 이상적인 일 가정 양립 방안, 성역할 태도 및 저출산 원인에 대한 견해 등을 성별 및 교육정도에 따라 알아보고 이들 사이의 관계를 탐색적으로 분석해 보았다. 이를 통해 향후 저출산 문제 해결을 위해 미혼 남녀들의 일 가정 양립을 어떻게 지원할 것이며, 이 과정에서 미혼 남녀의 성역할 태도가 어떻게 변화되어야 할 것인가를 유추해 보고자 했다. 연구결과를 정리하면, 첫째, 이상적인 일 가정 양립 방안은 미혼자의 성별에 따라 차이가 없었으나 교육정도에 따라서는 통계적으로 유의한 차이가 드러났다. 둘째, 이상적인 일 가정 양립방안과 부부 성역할 태도 및 성별 간 관계에 있어서는 여성에 비해 남성이 '남성은 직장, 여성은 가사'를 더 찬성했으며, 전일제일 보다 시간제 일을 선호하는 미혼자들이 '남성은 직장, 여성은 가사' 방안에 대한 찬성이 높았다. '남편의 자녀 돌봄 능력'에 대해서는 여성이 남성보다 그리고 2자녀를 두고 전일제로 일하겠다는 미혼자가 1자녀를 두고 전일제로 일하겠다는 미혼자에 비해 높은 평가를 보였다. 셋째, 두 자녀 이상을 두고 전일제로 일하고자 하는 미혼 남녀가 저출산 문제를 가장 심각하게 받아들이고 있었다. 넷째, 저출산 이유로 가장 높은 동의를 보인 것은 '양육비와 교육비용'이었으며 다음으로 '주택마련의 어려움'과 '취업여성의 증가'였다. "취업여성의 증가"를 저출산의 원인으로 여기는 정도는 남성보다 여성이 높게 나타났으며, 무자녀로 전일제 일하는 것을 원하는 미혼자들에게서 이러한 성향이 두드러지게 나타났다. 이러한 연구결과를 통해 일 가정 양립방안과 성역할 태도에 대한 기본적인 이해를 높일 뿐만 아니라 저출산 문제에 대한 정책적 개입방향을 제시하고자 하였다.

• 보건의료산업학회지
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• 제8권3호
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• pp.137-145
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• 2014

The objective of this study was to analyze the risk of preterm birth (PTB) and low birth weight (LBW) in extramarital birth by analyzing 2008-2012 birth certificated data (2,328,719 births) from Korea Statistics. Odds ratio and 95% confidence intervals (95% CI) were calculated from logistic regression analyses to describe the associations between PTB & LBW and extramarital birth adjusted for maternal age, maternal occupation & education, infantile sex, birth order and number of child birth (singleton & multiple birth). The rate of extramarital birth was 1.8 percent and 2.1 percent in 2010-11. The incidence of LBW was 8.1 percent in extramarital birth and 5.0 percent in marital birth. The incidence of PTB in extramarital birth were 8.2 percent and 5.8 percent in marital birth. Compared with marital birth, the odds ratio (OR) for PTB were 1.48 (95% CI: 1.43-1.54) for extramarital birth. Risk of LBW was higher in extramarital birth (OR: 1.70, 95% CI: 1.64-1.76) than that of marital birth. Among mothers younger than 20 years, the odds ratio of PTB among extramarital birth, relative to married birth was 1.69 (1.49-1.91). Among unmarried mothers, those at a higher risk of LBW was aged 20-29 years (1.69: 1.59-1.79). Maternal unmarried status was associated with increased risk of PTB and LBW.

• Asian-Australasian Journal of Animal Sciences
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• 제31권2호
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• pp.237-244
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• 2018

Objective: Piglet pre-weaning mortality is an important variable indicating the efficacy of farrowing management and animal well-being during lactation. The present study determined the association of newborn traits measured soon after birth with piglet pre-weaning mortality and growth. Methods: In total, 805 piglets born from 57 multiparous sows were investigated. Their blood oxygen saturation, blood glucose and rectal temperature at 24 h after birth (RT24h) were monitored. Birth order, sex, skin color, integrity of the umbilical cord, attempts to stand and birth intervention were monitored. Piglets were weighed at day 0, 7, and 21 to evaluate average daily gain (ADG). Results: Piglet pre-weaning mortality for lactation period was 12.6% and cumulative mortality during the first 7 days of age was 8.6%. A higher proportion of piglets with pale skin color died compared to piglets with normal skin color (26.7% vs 7.7%, p<0.001). A higher (p<0.001) proportion of piglets that attempted to stand after 5 min (38.5%) died compared to piglets that attempted to stand within 1 min (6.3%) after birth. Piglet body weight at birth ($BW_B$), blood glucose and the number of piglets born alive (BA) were correlated with ADG (p<0.05). Piglets with $BW_B$ <1.30 kg had higher (p<0.001) mortality rate than piglets with $BW_B{\geq}1.80 kg$ (19.0% vs 3.3%) and piglets with $BW_B$ 1.30 to 1.79 kg (4.0%). Piglet with RT24h <$37.0^{\circ}C$ had higher (p<0.001) mortality rate (86.2%) than piglets with RT24h >$38.5^{\circ}C$ (3.9%). Conclusion: Low $BW_B$ and low RT24h compromise piglet survival during the lactation period in the tropical conditions. Piglets in the litters with a high BA, low $BW_B$ and low blood glucose have reduced ADG.

• Journal of Preventive Medicine and Public Health
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• 제44권3호
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• pp.111-117
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• 2011

Objectives: This study measured the impact of shifts in maternal age and parity on the increase in the low birth weight (LBW) rate in Korea. Methods: We obtained raw data for all 6 397 945 live births registered at the Korea National Statistical Office between 1995 and 2005. We calculated the proportion of increment in the LBW rate due to changes in the distribution of maternal age and parity (AP-dis) and the proportion due to changes in the age- and parity-specific LBW rate (AP-spe). Results: The LBW rate increased from 3.02% in 1995 to 4.28% in 2005. The multiple birth rate increased from 1.32% to 2.19% during the same period. Of the 1.26% points increment in the LBW rate, 0.64% points occurred among singleton births and 0.62% points occurred among multiple births. Changes in the AP-dis accounted for 50% of the increase in the LBW rate among singleton births, but did not contribute to the increase in the LBW rate among multiple births. The remainder of the total increment in the LBW rate was explained by the increase in the AP-spe. Conclusions: This study demonstrated that shifts in maternal age and parity among singleton births and increased multiple births were important contributors to the increment in the LBW rate. This study also revealed that the increase in the AP-spe was an equally important contributor as the shifts in maternal age and parity to the increment in the LBW rate among singleton births and was a major contributor among multiple births.

• Asian-Australasian Journal of Animal Sciences
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• 제12권1호
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• pp.5-8
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• 1999

Weight records from birth to calving and calving scores of 407 two-year old heifers and weights of their offspring from birth to one year of age were used to study the effects of sire birth weight on maternal traits of their female progeny. The heifers ($G_1$) were Ihe progeny of 81 sires ($G_0$) and were classified into three classes based on their sires' birth weights (High, Medium and Low). The heifers were from three distinct breed-groups and were mated to bulls with medium birth weights within each breed-group to produce the second generation ($G_2$). The data were analyzed using a covariance model. The female progeny of high birth-weight sires were heavier from birth to calving than those sired by medium and low birth-weight bulls. The effect of sire birth weight on calving difficulty scores of their female progeny was not significant. Grand progeny (G2) of low birth-weight sires were lighter at birth than those from high birth-weight sires (p < 0.05) but they did not differ significantly in weaning and yearling weights from the other two Grand progeny groups. The results indicated that using low birth weight sires would not result in an increase in the incidence of dystocia among their female progeny calving at two-year of age and would not have an adverse effect On weaning and yearling weights of their grand progeny.