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Effects of Sahyangsohap-won on Cerebral Hemodynamics in Healthy Subjects (사향소합원(麝香蘇合元)이 정상인의 뇌혈류역학에 미치는 영향)

  • Koo, Bon-Soo;Kim, Sung-Hwan;Moon, Sang-Kwan;Cho, Ki-Ho;Kim, Young-Suk;Bae, Hyung-Sup;Lee, Kyung-Sup;Ryu, Soon-Hyun
    • The Journal of Internal Korean Medicine
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    • v.22 no.2
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    • pp.199-205
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    • 2001
  • Background and Purpose : Transcranial doppler ultrasonography(TCD) is a noninvasive and nonradioactive technique for evaluation of the hemodynamics in large cerebral vessels. Sahyangsohap-won(SS) has been considered to be effective for the treatment of various disease, especially cerebrovascular, cardiovascular, and psychosomatoform disorders. But, there is no study about the effect of SS on the cerebral hemodynamics in humans. The aim of this study was to assess the effect of SS on the changes in cerebral hemodynamics and the dose-dependant effect by using TCD. Subjects and Methods : 30 healthy subjects were randomly divided into three group: group 1 took no drug, group 2 took SS one pill, and group 3 took SS 2 pills. Changes in the mean blood flow velocity(MBFV) and pulsatility index(PI) in the middle cerebral artery were evaluated by means of TCD. We obtained hypercapnia with breath-holding and evaluated cerebrovascular reactivity with the breath-holding index(BHI). Systolic blood pressure(SBP), diastolic blood pressure(DBP), and heart rate(HR) were measured by means of ambulatory blood pressure monitoring. In group 2 and group 3, the evaluations were performed during the baseline and were repeated at 20, 40, and 60 minutes after SS administration. In group 1, the evaluation was performed at corresponding time intervals. Results : In mean values of MSFV, PI, SSP, DBP, and HR, no stastically significant differences were found between the 3 groups. However, BHI values were significantly lower in groups 2 and 3 than in group 1 at 40 minutes after SS administration(P<0.05, group 1 vs group 2, group 1 vs group 3 by post-hoc analysis: Scheffe's test) but in dose-dependant effect, there was no difference between group 2 and group 3. Conclusion : These results suggest that SS can decrease vascular resistance in cerebral small arteries or arterioles and enhance their distensibility. Further studies on larger numbers of subjects are needed to confirm these effects and the dose-dependant effects.

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Analysis on Looped Stage-Discharge Relation and Its Simulation using the Numerical Model (수치모형을 이용한 고리형 수위-유량 관계 분석)

  • Kim, Ji Sung;Kim, Won;Kim, Dong Gu;Kim, Chi Young
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.29 no.1B
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    • pp.1-9
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    • 2009
  • This study is focused on the analysis of loop characteristics of stage-discharge relation which is widely used for the production of discharge data and the simulation of loop stage-discharge relation using the numerical model. Analysis of consecutive stage and discharge data at 3 points revealed that loop of stage-discharge relationship is very strong. This means that the existing single stage-discharge relation may include large amount of error. Various flood events are simulated in mainstream of Han river with one-dimensional numerical model. The calculated stage data are compared with measured data. Especially continuous field-flow measurements concurrently collected with an Acoustic Doppler Velocity Meter (ADVM) on Hangang bridge in the case of 2007 flood event are used to verify the model applicability of estimating flows in open channels. This comparison shows that numerical model is an accurate and reliable alternative for making the real stage-discharge relation. Simulation of stage-discharge relation by a numerical model at Paldang and Hangang bridge showed good agreements with measured one, so it may be possible to generate real loop stage-discharge relation with properly calibrated and verified numerical model. It can be concluded that results of this study can contribute to error analysis of conventional single stage-discharge relation and development of loop stage-discharge relation with numerical model.

A Three-Dimensional Modeling Study of Lake Paldang for Spatial and Temporal Distributions of Temperature, Current, Residence Time, and Spreading Pattern of Incoming Flows (팔당호 수온, 유속, 체류시간의 시.공간적 분포 및 유입지류 흐름에 관한 3차원 모델 연구)

  • Na, Eun-Hye;Park, Seok-Soon
    • Journal of Korean Society of Environmental Engineers
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    • v.27 no.9
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    • pp.978-988
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    • 2005
  • A three-dimensional dynamic model was applied to Lake Paldang, Han River in this study. The model was calibrated and verified using the data measured under different ambient conditions. The model results were in reasonable agreements with the field measurements in both calibration and verification. Utilizing the validated model, we analyzed the spatial and temporal distributions of temperature, current, residence time, and spreading pattern of incoming flows within the lake. Relatively low velocity and high temperature were computed at the surface layer in the southern region of the Sonae island. The longest residence time within the lake was predicted in the southern region of the Sonae island and the downstream region of the South Branch. This can be attributed to the fact that the back currents caused by the dam blocking occur mainly in these regions. Vertical thermal profiles indicated that the thermal stratifications would be occurred feebly in early summer and winter. During early spring and fall, it appeared that there would be no discernible differences at the vertical temperature profiles in the entire lake. The vertical overturns, however, do not occur during these periods due to an influence of high discharge flows from the dam. During midsummer monsoon season with high precipitation, the thermal stratification was disrupted by high incoming flow rates and discharges from the dam and very short residence time was resulted in the entire lake. In this circulation patterns, the plume of the Kyoungan stream with smallest flow rate and higher water temperature tends to travel downstream horizontally along the eastern shore of the south island and vertically at the top surface layer. The model results suggest that the Paldang lake should be a highly hydrodynamic water body with large spatial and temporal variations.

Kinematics of the Northern Filament in Orion Molecular Clouds Complex Using 12CO Molecular Observation Data (12CO 분자선 관측 자료를 이용한 오리온 분자운 복합체내 북쪽 필라멘트의 운동학 연구)

  • Jo, Hoon;Sohn, Jungjoo;Kim, ShinYoung;Lee, JeeWon;Kim, Sungsoo S.;Morris, Mark
    • Journal of the Korean earth science society
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    • v.39 no.6
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    • pp.519-532
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    • 2018
  • We investigated the effect of galactic plane toward molecular motion and kinematics in the northern filament (NF) of Orion Molecular Clouds Complex (OMC) using $^{12}CO$ (J=1-0) line. Observed data were from three areas including NF1, NF2, and NF3 in far-out order from galactic plane, for a total 270 hours by Seoul National University Radio Astronomy Observatory (SRAO) 6m telescope, with 2arcmin spatial resolution. galactic plane and OMC NF were connected to each other along the magnetic field at a density of 3% for $^{12}CO$ (J=2-1) and 9% for the case of dust. $^{12}CO$ (J=1-0), $^{12}CO$ (J=2-1), and interstellar dusts were distributed uniformly in NF3, but only in certain regions with relatively high density in NF1 and NF2. NF showed a single structure, partial shrinking motion in NF1, and rotational motion at the bottom of NF2, and spiral rotation associated with magnetic field only in NF3. The position-velocity analysis showed that the materials including $^{12}CO$ (J=1-0) could flow toward galactic plane along NF2 and NF3. However, there was no clear cause for the material to flow toward galactic plane in this result. Further detailed observation for rotational motion at the top of NF1 and NF2 might help to confirm it.

Pilot-scale Applications of a Well-type Reactive Barrier using Autotrophic Sulfur-oxidizers for Nitrate Removal (독립영양 황탈질 미생물을 이용한 관정형 반응벽체의 현장적용성 연구)

  • Lee, Byung-Sun;Um, Jae-Yeon;Lee, Kyu-Yeon;Moon, Hee-Sun;Kim, Yang-Bin;Woo, Nam-C.;Lee, Jong-Min;Nam, Kyoung-Phile
    • Journal of Soil and Groundwater Environment
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    • v.14 no.3
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    • pp.40-46
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    • 2009
  • The applicability of a well-type autotrophic sulfur-oxidizing reactive barrier (L $\times$ W $\times$ D = $3m\;{\times}\;4\;m\;{\times}\;2\;m$) as a long-term treatment option for nitrate removal in groundwater was evaluated. Pilot-scale (L $\times$ W $\times$ D = $8m\;{\times}\;4\;m\;{\times}\;2\;m$) flow-tank experiments were conducted to examine remedial efficacy of the well-type reactive barrier. A total of 80 kg sulfur granules as an electron donor and Thiobacillus denitrificans as an active bacterial species were prepared. Thiobacillus denitrificans was successfully colonized on the surface of the sulfur granules and the microflora transformed nitrate with removal efficiency of ~12% (0.07 mM) for 11 days, ~24% (1.3 mM) for 18 days, ~45% (2.4 mM) for 32 days, and ~52% (2.8 mM) for 60 days. Sulfur granules attached to Thiobacillus denitrificans were used to construct the well-type reactive barrier comprising three discrete barriers installed at 1-m interval downstream. Average initial nitrate concentrations were 181 mg/L for the first 28 days and 281 mg/L for the next 14 days. For the 181 mg/L (2.9 mM) plume, nitrate concentrations decreased by ~2% (0.06 mM), ~9% (0.27 mM), and ~15% (0.44 mM) after $1^{st}$, $2^{nd}$, and $3^{rd}$ barriers, respectively. For the 281 mg/L (4.5 mM) plume, nitrate concentrations decreased by ~1% (0.02 mM), ~6% (0.27 mM), and ~8% (0.37 mM) after $1^{st}$, $2^{nd}$, and $3^{rd}$ barriers, respectively. Nitrate plume was flowed through the flow-tank for 49 days by supplying $1.24\;m^3/d$ of nitrate solution. During nitrate treatment, flow velocity (0.44 m/d), pH (6.7 to 8.3), and DO (0.9~2.8 mg/L) showed little variations. Incomplete destruction of nitrate plume was attributed to the lack of retention time, rarely transverse dispersion, and inhibiting the activity of denitrification enzymes caused by relatively high DO concentrations. For field applications, it should be considered increments of retention time, modification of well placements, and intrinsic DO concentration.

Dynamic Behavior of Model Set Net in the Flow (모형 정치망의 흐름에 대한 거동)

  • Jung, Gi-Cheul;Kwon, Byeong-Guk;Le, Ju-Hee
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.33 no.4
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    • pp.275-284
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    • 1997
  • This experiment was carried out to measure the sinking depth of each buoy, the change in the net shape of the net, and the tension of sand bag line according to the R (from bag net to the fish court) and L (from fish court to the bag net) current directions and their velocity by the model experiment. The model net was one-fiftieth of the real net, and its size was determined after considering the Tauti’s Similarity Law and the dimension of the experimental tank. 1. The changes of the net shape were as follows : In the current R, the end net of fish court moved 20mm down the lowerward tide and 10mm upper part. So the whole model net moved up at 0.2m/sec. The shape of the net showed an almost linear state from bag net to the fish court at 0.6m/sec. In the current L, the door net moved 242mm down the lowerward tide and 18mm upper part. So the whole model net moved up at 0.2m/sec. The net shape showed an almost linear state from the fish court to the bag net at 0.5m/sec. 2. The sinking depths of each buoy were as follows: In the current R, the head buoy started sinking at 0.2m/sec and sank 20mm, 99mm at 0.3m/sec and 0.6m/sec, respectively. The end buoy didn't sink from 0m/sec to 0.6m/sec but showed a slight quake. In the current L, the end buoy started sinking at 0.1m/sec, and sank 5mm and 108mm at 0.2m/sec and 0.6m/sec, respectively. The whole model net sank at 0.5m/sec except the head buoy. 3. The changes of the sand bag line tension were as follows: In the current R, the tension affected by the sand bag line of the head buoy showed 273.51g at 0.1m/sec increased to 1298.40g at 0.6m/sec. In the current L, the tension affected by the sand bag line of the end buoy on one side showed 137.08g at 0.1m/sec increased to 646.00g at 0.6m/sec. The changes in the sand bag line tension were concentrated on the sand bag line of the upperward tide with increasing velocity at the R and L current directions. However, no significant increase in tension was observed in the other sand bag lines.

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A Study on Anaerobic Treatment and Energy Recovery Technology of Food Waste by Using Hybrid Anaerobic Reactor (Hybrid Anaerobic Reactor를 이용한 음식물쓰레기의 혐기성처리 및 에너지 회수에 관한 연구)

  • Yoon Young-Bong;Park Jin-Young;Ju Jin-Young;Kim Myung-Ho
    • Journal of environmental and Sanitary engineering
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    • v.20 no.1 s.55
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    • pp.64-75
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    • 2005
  • The total production of food waste was about 11,398ton/day('03) in Korea. Also, food waste was treated by landfill, incineration, reuse and anaerobic digestion. The method of food waste treatment depended primarily on landfill. However, the method of landfill causing social problems was prevented to treat food waste in the first of January 2005.12) Thus, anaerobic digestion is an important method to treat food waste because of possibility of energy recovery as methane gas. In this study, the possibility of food waste treatment containing high organic material and low pH in the one stage anaerobic reactor to save cost and time and energy recovery using $CH_{4}$ gas by the hybrid anaerobic reactor (HAR) was measured. The HAR was designed by combing the merits of the anaerobic filter (AF) to minimize the microorganism shock when food waste of very low pH was injected and up-flow anaerobic sludge blanket (UASB) to prevent from plugging and channeling phenomena by large suspended solids when semi solids were injected. Granule was packed in the section of HAR. The purpose of the BMP experiment was to measure the amount of methane generated when organic material was resolved under anaerobic conditions, to grasp bio resolution of organic material. Total accumulated methane production per VS amount was $0.471(m^{3}/\cal{kg}\;VS)$. So, the value was about $81.2\%$ of theoretical methane production which was $0.58(m^{3}/\cal{kg}\;VS)$ by elementary analysis and organic matter removal velocity (K) was $0.18(d^{-1})$. From these results, food waste was treated by anaerobic treatment. From this study, $CH_{4}$ generation from food waste (11,398 ton/day) could be estimated. By using an energy conversion factor of Braun's study, $5.97KWh/m^{3}\;CH4,\;60\%\;of\;CH_{4}$ gas generation, the amount of total energy producing food waste is to 6,727MWh/day. It could be confirmed that energy recovery using $CH_{4}$ gas was possible. Above these results, food waste containing organic matters of high concentration could be treated in HRT 30 days under an anaerobic condition, using the hybrid anaerobic reactor and reuse of $CH_{4}$ gas was possible.

Development of Rain Shelter for Chinese Cabbage Rainproof Cultivation (배추재배용 비가림하우스 개발)

  • Yu, In Ho;Lee, Eung Ho;Cho, Myeong Whan;Ryu, Hee Ryong;Moon, Doo Gyung
    • Journal of Bio-Environment Control
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    • v.23 no.4
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    • pp.293-302
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    • 2014
  • This study was carried out to develop rain shelter which can make an appropriate size and environment for Chinese cabbage rainproof cultivation. Fifty three farms with chinese cabbage rainproof cultivation system have been investigated to set up width and height of rain shelter. Mostly the width of 6m was desired for rain shelter and the height of 1.6m for their eaves, so these values were chosen as the dimensions for rain shelter. After an analysis of their structural safety and installation costs by the specifications of the rafter pipe, Ø$25.4{\times}1.5t$ and 90cm have been set as the size of rafter that such size costs the least. This size is stable with $27m{\cdot}s^{-1}$ of wind velocity and 17cm of snow depth. Therefore it is difficult to apply this dimension to area with higher climate load. In order to sort out such problem, the rain shelter has been designed to avoid damage on frame by opening plastic film to the ridge. Once greenhouse band is loosen by turning the manual switch at the both sides of rain shelter and open button of controller is pushed then switch motor rises up along the guide pipe and plastic film is opened to the ridge. Chinese cabbage can be damaged by insects if rain shelter is opened completely as revealed a field. To prevent this, farmers can install an insect-proof net. Further, the greenhouse can be damaged by typhoon while growing Chinese cabbage therefore the effect of an insect-proof net on structural safety has been analyzed. And then structural safety has been analyzed through using flow-structure interaction method at the wind condition of $40m{\cdot}s^{-1}$. And it assumed that wind applied perpendicular to side of the rain shelter which was covered by insect-proof net. The results indicated that plastic film was directly affected by wind therefore high pressure occurred on the surface. But wind load on insect-proof net was smaller than on plastic film and pressure distribution was also uniform. The results of structural analysis by applying pressure data extracted from flow analysis indicated that the maximum stress occurred at the end of pipe which is the ground part and the value has been 54.6MPa. The allowable stress of pipe in the standard of structural safety must be 215 MPa or more therefore structural safety of this rain shelter is satisfied.

Summer-Time Behaviour and Flux of Suspended Sediments at the Entrance to Semi-Closed Hampyung Bay, Southwestern Coast of Korea (만 입구에서 부유퇴적물 거동과 플럭스: 한반도 서해 남부 함평만의 여름철 특성)

  • Lee, Hee-Jun;Park, Eun-Sun;Lee, Yeon-Gyu;Jeong, Kap-Sik;Chu, Yong-Shik
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.5 no.2
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    • pp.105-118
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    • 2000
  • Anchored measurements (12.5 hr) of suspended sediment concentration and other hydrodynamic parameters were carried out at two stations located at the entrance to Hampyung Bay in summer (August 1999). Tidal variations in water temperature and salinity were in the range of 26.0-27.9$^{\circ}C$ and 30.9-31.5, respectively, indicating exchange offshore and offshore water mass. Active tidal mixing processes at the entrance appear to destroy the otherwise vertical stratification in temperature and salinity in spite of strong solar heating in summer. On the contrary, suspended sediment concentrations show a marked stratification with increasing concentrations toward bottom layer. Clastic particles in suspended sediments consist mostly of very fine to fine silt (4-16 ${\mu}$m) with a poorly-sorted value of 14.7-25.9 ${\mu}$m. However, at slack time with less turbulent energy, flocs larger than 40 ${\mu}$m are formed by cohesion and inter-collision of particles, resulting in a higher settling velocity. Strong ebb-dominated and weak flood dominated tidal currents, in the southwestern and the northeastern part, respectively, result in a seaward residual flow of -10${\sim}$-20 cm $s^{-1}$ at station H1 and a bayward residual flow less than 5.0 cm $s^{-1}$ at station H2. However, mean concentration of suspended sediments at station H1 is higher at flood (95.0-144.1 mg $1^{-1}$) than in ebb (75.8-120.9 mg $1^{-1}$). On the contrary, at the station H2, the trend is reversed with higher concentration at the ebb (84.7-158.4 mg $1^{-1}$) than that at the flood (53.0-107.9 mg $1^{-1}$). As a result, seaward net suspended sediment fluxes ($f_{s}$) are calculated to be -1.7 ${\sim}$-$15.610^{3}$ kg $m^{-2}$ $s^{-1}$ through the whole water column. However, the stations H1 and H2 show definitely different values of the flux with higher ones in the former than in the latter. Alternatively, depth-integrated net suspended sediment loads ($\c{Q}_{s}$) for one tidal cycle are also toward the offshore with ranges of 0.37${\times}$$10^{3}$ kg $m^{-1}$ and 0.21${\times}$$10^{3}$ kg $m^{-1}$, at station H1 and H2, respectively. This seaward transport of suspended sediment in summer suggests that summer-time erosion in the Hampyung muddy tidal flats is a rather exceptional phenomenon compared to the general deposition reported for many other tidal flats on the west coast of Korea.

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Study on Change of Algae Occurrence Before & After Gangcheon and Ipoh Weir Construction at Namhan River (남한강 강천보와 이포보 건설 전·후 조류 발생의 변화에 대한 연구)

  • Chae, Soo-Kwon;Oh, Seung-Eun;Chun, Seung-Hoon;Ahn, Hong-Kyu
    • Journal of Wetlands Research
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    • v.18 no.4
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    • pp.394-403
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    • 2016
  • This study was carried out to verify change and relationship between the concentration of chlorophyll-a and environmental factors including weather, water quality and discharge at before & after Gangcheon and Ipoh weir construction at Namhan river, based on the weather and water quality data provided by the measuring network. We classified the period of before & after weir construction by the cluster analysis with Ward's method, and also through the correlation analysis between the concentration of chlorophyll-a and environmental factors, the influence factors related with algae occurrence(Chlorophyll-a) were analyzed. The result by cluster analysis based on data of the total 12 factors (water temperature, rainfall, daylight, pH, DO, BOD, COD, T-N, $NH_3-N$, $NO_3-N$, T-P, $PO_4-P$) from 2005 to 2015 indicated a clear classification into two periods, before(2006-2007) & after (2012-2013) weir construction. After weir construction, class of BOD at Gangcheon weir was better than before, changed from II class to Ia class, and likewise class of BOD at Ipoh weir was improved from II-III class to Ia-IIclass. Also T-P and T-N concentration also were to be improved in general after weir construction. Concentraion of Chlorophyll-a afterGangcheon and Ipoh weir construction was to be decreased. However, frequency of algae warning was increased from 9 to 15 after Ipoh weir construction due to increasing of HRT and water temperature. After weirs construction, the result of correlation analysis between weather, water quality and discharge and concentration of chlorophyll-a indicated a positive correlation, order of BOD(0.579) > COD(0.413) > temperature(0.237), and a negative correlation, order of $NO_3-N$(-0.344) > T-N(-0.293) at Gangcheon weir. And there were likewise positive correlation, order of BOD(0.795) > pH(0.581) > Water temperature(0.422), and negative correlation, order of $NO_3-N$(-0.457) > T-N(-0.371) > $NH_3-N$(-0.326) > $PO_4-P$(-0.288) > Discharge(-0.213) after Ipoh weir construction. Although water quality after Ipoh weir construction was generally improved, increase of frequency of algae warning occurrence was influenced by change of water conditions such as reduction of the velocity, increase of HRT and water temperature, etc impacted strongly by change of the stream flow more than change of water environments after weir construction.