• Title/Summary/Keyword: A case control study

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Abdominal Obesity as a Risk Factor of Ischemic Stroke in Case-control study (복부비만과 허혈성 뇌졸중)

  • Yim, Hee-Sun;Ko, Seong-Gyu
    • Journal of Korean Medicine for Obesity Research
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    • v.2 no.1
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    • pp.25-36
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    • 2002
  • Objective: The purposes of this study are to know the relations of abdominal obesity and ischemic stroke and to know what index could represent the abdominal obesity appropriately. Methods. We have done case-control study and recruited 97 ischemic stroke patients and 117 controls. Case is matched by control by individual matching. All participants had questionnaire, interview and then were examined waist-hip ratio, waist circumference and body mass index. Results : WC, WHR and Hypertension history had differences in two groups, case and control groups. But BMI and other factors weren't significant. According to Quartile of Waist Circumference, the two groups had the differences in hypertension history, diabetes history, smoking status, WHR, BMI, and weight and in the Quartile of Waist-Hip Ratio Quartile, past history of hypertension and diabetes, WC, BMI and weight had the significances. Sex, Age Adjusted and Multivariate Odds Ratio (95% Confidence Interval) of WC Quartile are 2.083, 1.628, 4.491 and 4.418, 4.964, 12.306, and in WHR, the Ors are 2.252, 5.743, 15.776 and 2.632, 8.918, 23.596. Conclusions: We knew from these results that abdominal obesity is very important risk factor of ischemic stroke and WHR more than WC is a good indicator of abdominal obesity, so we should reduce the WHR to prevent of ischemic stroke.

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Analysis of Nested Case-Control Study Designs: Revisiting the Inverse Probability Weighting Method

  • Kim, Ryung S.
    • Communications for Statistical Applications and Methods
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    • v.20 no.6
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    • pp.455-466
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    • 2013
  • In nested case-control studies, the most common way to make inference under a proportional hazards model is the conditional logistic approach of Thomas (1977). Inclusion probability methods are more efficient than the conditional logistic approach of Thomas; however, the epidemiology research community has not accepted the methods as a replacement of the Thomas' method. This paper promotes the inverse probability weighting method originally proposed by Samuelsen (1997) in combination with an approximate jackknife standard error that can be easily computed using existing software. Simulation studies demonstrate that this approach yields valid type 1 errors and greater powers than the conditional logistic approach in nested case-control designs across various sample sizes and magnitudes of the hazard ratios. A generalization of the method is also made to incorporate additional matching and the stratified Cox model. The proposed method is illustrated with data from a cohort of children with Wilm's tumor to study the association between histological signatures and relapses.

The Analysis of Relation between Cigarette Smoking and Stroke; case-control study (흡연과 중풍발생의 상관관계에 관한 환자-대조군 연구)

  • 양대진;배종면;이경섭;조기호;김영석;배형섭
    • The Journal of Korean Medicine
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    • v.22 no.4
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    • pp.69-78
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    • 2001
  • Objectives : It is known that cigarette smoking is associated with increased risk of both thrombotic and hemorrhagic stroke. However, in Korea, especially in the academic world of Korean Medicine, there is a lack of study about the relation between cigarette smoking and stroke. We carried out a case-control study to clarify the relation between cigarette smoking and stroke. Method : We interviewed 441 stroke patients (236 men, 205 women) as a case group and 432 non-stroke patients (208 men, 224 women) as a control group. We investigated the smoking pattern of all patients and stroke-subtype of the case group. Smoking pattern is classed into two (Class I), four (Class II) and five groups (Class III). Class I consists of current non-smokers and current smokers. Class II consists of non-smokers, former smokers, current light smokers and current heavy smokers. Class III consists of never smoked, secondhand smokers, former smokers, Current light smokers and current heavy smokers. Stroke-subtype consists of cerebral infarction and cerebral hemorrhage. Results : The percentage of current smokers of case group is higher significantly than that of control group. The number of cigarettes smoked per day is associated positively with the risk of stroke. According to our study, generally cigarette smoking is related with ischemic stroke. The percentage of secondhand smokers of the case group is lower than that of the control group. According to our study, characteristically secondhand smoking is associated with hemorrhagic stroke. Conclusions : From the above results we found that cigarette smoking is an important risk factor of stroke - especially cerebral infarction - and the number of cigarettes smoked per day is associated positively with the risk of stroke. Characteristically according to our study, secondhand smoking is associated with hemorrhagic stroke. Overall we conclude that cigarette smoking may be an important preventable factor for stroke.

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Case-control Study of Risk Factors for Non-Hodgkin Lymphoma in Mumbai, India

  • Balasubramaniam, Ganesh;Saoba, Sushama;Sarade, Monika;Pinjare, Suvarna
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.2
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    • pp.775-780
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    • 2013
  • Background: In the year 2010, it is estimated that nearly 0.36 million new cases and 0.19 million deaths with Non-Hodgkin lymphoma occurred. In India, among males, NHL incidence rates vary across the country which has encouraged us to conduct a case-control study to study risk factors. Materials and Methods: The present unmatched hospital-based case-control study conducted at Tata Memorial Hospital included subjects registered between the years 1997-99. There were 390 'lymphoma cases' and 1,383 'normal controls. Results: Data on age, tobacco habits, occupational history, dietary factors, tea, coffee were collected by the social investigators. Univariate and multivariate methods were applied for obtaining the odds ratios for risk factors. Conclusions: In the study, cigarette smoking (OR=2.0) and bidi smoking (OR=2.8), were associated with excess risk of lymphoma. Among the dietary items, only consumption of mutton showed 7.3-fold significant excess risk for lymphoma. Consumption of milk showed a 6-fold excess risk (OR=1.5); while coffee showed a 50% reduction in risk for lymphoma. Among occupational exposure, exposure to use of pesticides showed 3-fold excess risk for lymphoma.

Effects of Case-based Small Group Learning about Care of Infected Children for Daycare Center Teachers (보육교사를 위한 감염관리 사례기반 소그룹 학습안의 개발 및 효과)

  • Choi, Eun Ju;Hwang, Seon Young
    • Journal of Korean Academy of Nursing
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    • v.42 no.6
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    • pp.771-782
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    • 2012
  • Purpose: This study was conducted to develop and implement a case-based small group learning program on the care of children with infectious disease, and to examine its effects on knowledge, attitude and preventive practice behaviors of daycare center teachers compared to a control group. Methods: Based on the need assessment, the case-based learning program for the management of infectious children was developed. For this quasi-experimental study, 69 teachers were recruited from 14 child daycare centers in a city located in J province. Thirty four teachers were assigned to experimental group and participated in the case-based small group learning once a week for 5 weeks. Data were analyzed using the SPSS 18.0 program to perform ${\chi}^2$-test and t-tests. Analysis of covariance was used to treat the covariate of the number of assigned children between experimental and control groups. Results: The experimental group showed significantly higher posttest scores in knowledge, attitude and preventive practice behaviors than those of control group (p<.001). Conclusion: These findings indicate that case-based small group learning is an effective educational strategy for daycare center teachers to learn infection management through the emphasis of self-reflection and discussion.

Effect of Case Management Intervention Program for Registered Clients with Home Health Care of Hypertension (고혈압 대상자의 방문간호 중재프로그램의 효과)

  • Oh, Suk-Hee;Kim, Yong-Soon;Park, Jee-Won;Yoo, Moon-Sook
    • Journal of Home Health Care Nursing
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    • v.17 no.1
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    • pp.28-35
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    • 2010
  • Purpose: The study compared the hypertension care efficacy of a case management intervention program for registered clients. Methods: The nonequivalent control group pretest-posttest design involved 53 registered hypertensive patients of a customized visiting health care service in S-city(n=28 experimental group, n=25 control group). Data collection and case management intervention were carried out from April to July, 2009. The experimental group had six home visits and two phone calls, and the control group had two home visits during the 8-week period. Outcome variables for test hypotheses were changes in physiologic index (blood pressure and total cholesterol) and degree of self-management performance and confidence. Results: Repeated measure ANOVA and t-test of means revealed significant differences before and after program for systolic and diastolic blood pressure and self-management performance and confidence, but no significant difference concerning total cholesterol. Conclusion: A case management program can have positive effects on blood pressure control and self management. However, research is needed to create a more effective case management for vulnerable patient populations.

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Effects of Trunk Stability Exercise by using PNF on Trunk Control Ability and Balance, Gait in a Patient with Hemiplegia: A Single Case Study (PNF를 이용한 체간안정화운동이 뇌졸중 환자의 체간조절능력과 균형, 보행에 미치는 영향: 단일사례연구)

  • Jung, Du-Kyo
    • PNF and Movement
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    • v.13 no.4
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    • pp.203-213
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    • 2015
  • Purpose: Deficits in lower-extremity function and trunk control ability have a negative impact on individuals with hemiplegia. This case report aimed to describe the effect of trunk stability exercises using proprioceptive neuromuscular facilitation (PNF) on trunk control ability, balance, and gait in a patient with hemiplegia. Methods: A 77-year-old man with hemiplegia and trunk and lower extremity impairment participated in this four-week training intervention. Results: The patient demonstrated improvements in trunk control ability, balance, and gait performance. Outcome measures (Fugl-Meyer Assessment Lower Extremity (FMA-LE), Trunk Control Test, Berg Balance Scale, Timed Up and Go test, 10 Meter Walk test) were measured before and after the training program. Conclusion: The results of this case suggest that a trunk stability exercise using a PNF program may improve trunk control ability, balance, and gait in a patient with hemiplegia.

A Study on the Evaluation of Lighting Energy Consumption by Control Strategy of the Electric Lighting (전기조명 제어 전략에 따른 조명에너지 소비량 평가에 관한 연구)

  • Yun, Gyeong;Kim, Kang-Soo
    • KIEAE Journal
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    • v.12 no.1
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    • pp.119-125
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    • 2012
  • The objective of this study is to evaluate the electric lighting energy consumption carried out by Daysim program. A comparison between the measurement and simulated exterior global horizontal illuminance shows differences about 10% and it is very similar to the measurement. The interior illuminance simulated by Daysim are 18.9% lower than the measurement and simulated lighting energy consumption is 10% lower than the measurement. Corrected annual lighting energy simulation results show that the best case is the combination of occupancy switch-off and dimming system with automatic controlled blinds (E-3). In case of no blinds, it occasionally derives the minimum lighting energy consumption but it causes the glare, so we need to be careful for choosing the control strategy. For the overcast sky, the lighting energy consumption is not changed significantly by control strategy while the lighting energy in the clear sky is changed noticeably. So we must know the right strategy for each case to control the electric lights and blinds.

Study of Temperature Dynamic Characteristics of Various Control Methods for MGO Chiller System (MGO Chiller 시스템의 제어 방식에 따른 온도 동특성 연구)

  • Cho, Hee-Joo;Kim, Sung-Hoon;Choi, Jungho
    • Journal of Ocean Engineering and Technology
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    • v.33 no.2
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    • pp.139-145
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    • 2019
  • It is important that an MGO Chiller System, which is one of the sulfur oxide emission control technologies, is designed to meet the fuel temperature requirements, even with sudden engine load changes. Three different control algorithms (PI, Cascade, and MPC) were applied to an indirect MGO chiller system to compare and analyze the outlet temperature dynamic characteristics of the system through a case study. The results showed that the MPC control method had the best temperature following characteristics in the case study, and the temperature deviation range was reduced by approximately 5% compared to the PI control method.

Epstein-Barr Virus and Gastric Cancer Risk: A Meta-analysis With Meta-regression of Case-control Studies

  • Bae, Jong-Myon;Kim, Eun Hee
    • Journal of Preventive Medicine and Public Health
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    • v.49 no.2
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    • pp.97-107
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    • 2016
  • Objectives: Research on how the risk of gastric cancer increases with Epstein-Barr virus (EBV) infection is lacking. In a systematic review that investigated studies published until September 2014, the authors did not calculate the summary odds ratio (SOR) due to heterogeneity across studies. Therefore, we include here additional studies published until October 2015 and conduct a meta-analysis with meta-regression that controls for the heterogeneity among studies. Methods: Using the studies selected in the previously published systematic review, we formulated lists of references, cited articles, and related articles provided by PubMed. From the lists, only case-control studies that detected EBV in tissue samples were selected. In order to control for the heterogeneity among studies, subgroup analysis and meta-regression were performed. Results: In the 33 case-control results with adjacent non-cancer tissue, the total number of test samples in the case and control groups was 5280 and 4962, respectively. In the 14 case-control results with normal tissue, the total number of test samples in case and control groups was 1393 and 945, respectively. Upon meta-regression, the type of control tissue was found to be a statistically significant variable with regard to heterogeneity. When the control tissue was normal tissue of healthy individuals, the SOR was 3.41 (95% CI, 1.78 to 6.51; I-squared, 65.5%). Conclusions: The results of the present study support the argument that EBV infection increases the risk of gastric cancer. In the future, age-matched and sex-matched case-control studies should be conducted.