• Journal of Microbiology and Biotechnology
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• 제9권6호
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• pp.773-777
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• 1999

Scale-up experiments for hydrolysis of beef tallow, fat, and palm kernel with lipase derived from Candida cylindracea were carried out in 1-1, 100-1, and 10,000-1 reactors. The optimum agitation speed for the hydrolysis of the 1-1 reactor was investigated and found to be 350rpm, and this was a basis for the scale-up of agitation speed. The hydrolysis system in this work was the oil-water system in which the hydrolysis seems to process a heterogeneous reaction. An emulsion condition was the most important factor for determining the reaction rate of hydrolysis. Therefore, the scale-up of agitation speed was performed by using the power n = 1/3 in an equation of the rules of thumb method. The geometrical similarity for scaling-up turned out to be unsatisfactory in this study. Thus, the working volume per one agitator was used for the scale-up. In the case of scale-up from a 1-1 reactor to a 100-1 reactor, the hydrolysis of palm kernel was very much scaled-up by initiating the rules of thumb method. However, the hydrolysis of fat and beef tallow in a 100-1 reactor was a little higher than that of the 1-1 reactor because of the difference of geometrical similarity. The scale-up of hydrolysis from the 100-1 reactor to the 10,000-1 reactor was improved compared to that of the 1-1 to 100-1 reactor. The present results indicated that the scale-up of hydrolysis in the oil-water system by the rules of thumb method was more satisfactory under the condition of geometrical similarity. Even in the case where geometrical similarity was not satisfactory, the working volume per one agitator could be used for the scale-up of a heterogeneous enzyme reaction.

• 대한정형외과스포츠의학회지
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• 제1권2호
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• pp.143-148
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• 2002

목적: 임상적으로드물며, 발생시도수정복이잘안되는무지중수지관절복합탈구의임상적결과를알아보고자하였다.대상및방법: 무지중수지관절의외상성탈구11예(10예후방탈구, 1예전방탈구)를대상으로초기에탈구의정복가능성,도수정복을방해하는해부학적요인, 수술적접근법에관하여조사하였다.결과: 모든증례에서초기에도수정복을시도하였으나, 2예에서만이정복이되었다. 8 례는전방도달법으로관혈정복을하였고, 1예는만성적인소견을보여관절고정술을시행하였다. 정복방해요인은파열된수장판내로근위부에서단무지굴건과요측종자골이감입되어있었고, 중수골두는파열된인대와단무지굴건사이에형성된간격사이로빠져나와있었다.결론: 과신전에의한중수지관절의후방복합탈구는드물지만, 정복이쉽지않아서주로관혈정복이요구되며, 이때정복방해요인인파열된수장판과관절막, 단무지굴건과종자골등에관심을갖고치료에임하여야한다.

• 척추신경추나의학회지
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• 제17권2호
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• pp.101-108
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• 2022

Objectives Most of the acupuncture or dry needling points for trigger finger were limited around the metacarpophalangeal joint, A1 pulley, and flexor muscle tendon. Thus, this study aimed to report a case of a patient with trigger thumb which improved using dry needling on additional muscle points. Methods The author has investigated why additional points are needed including what its accompanying effects are. Dry needling and electro-dry needling have been conducted based on anatomical structure. Moreover, a follow-up observation was performed twice to evaluate if the effects of this treatment have been maintained. Treatment progress was evaluated using a numeric rating scale (NRS) and Quinnell's classification of trigger finger. Results After 28 days of treatment, NRS and Quinnell's trigger grade decreased significantly without adverse effects. The treatment effect has been maintained until follow-up observation. Conclusions Additional points are recommended for the radical treatment of trigger finger.

• 센서학회지
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• 제20권3호
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• pp.172-177
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• 2011

Finger patients can't use their hands because of the paralysis their fingers. Their fingers are recovered by rehabilitating training, and the rehabilitating extent can be judged by measuring the pressing force to be contacted with two fingers(thumb and first finger, thumb and middle finger, thumb and ring finger, thumb and little finger). At present, most hospitals have used a thin plastic-plate for measuring the two-finger grasping force, and we can only judge that they can grasp the plate with their two-finger through it, because the plate can't measure the two-finger grasping force. But, recently, the force measuring system for measuring two-finger grasping force was developed using three-axis force sensor, but it is very expensive, because it has a three-axis force sensor. In this paper, two-finger force measuring system with a one-axis force sensor which can measure two-finger grasping force was developed. The one-axis force sensor was designed and fabricated, and the force measuring device was designed and manufactured using DSP(Digital Signal Processing). Also, the grasping force test of men was performed using the developed two-finger force measuring system, it was confirmed that the grasping forces of men were different according to grasping methods, and the system can be used for measuring two-finger grasping force.

• Archives of Reconstructive Microsurgery
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• 제10권2호
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• pp.99-104
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• 2001

Purpose : Loss of sensibility over the finger tip resents a grave deficit and is an indication for sensible soft tissue reconstruction. This paper was performed to assess the long term results obtained by nerovascular island flap. Material and Methods : We performed neurovascular island graft for defective sensibility of finger tip loss in 94 cases since 1979 to 2000. The recipient sites were the thumb pulp defect in 79 cases, the amputated thumb in 9 cases, the amputated index in 4 cases, and the velar aspect of interphalangeal joint of thumb in 2 cases. The donor flaps were obtained from the radial side of ring finger in 63 cases, the ulnar side of the ring finger in 21 cases, and the ulnar side of the middle finger in 10 cases. A mean follow-up period was 5.7 years. Results : The flap quality was well vascularized and survived in 89 cases. The two-point discrimination was average 8.7mm. Because of scar contracture, the range of motion of the donor finger was decreased 3.5% of the normal finger in the distal interphalangeal joint, 8,2% in the proximal interphalangeal joint. A phenomenon of double sensibility occurred in 66 cases. Conclusion : This technique was excellent both aesthetically and functionally as a reconstruction of the Loss of fingertip.

• 한국정밀공학회지
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• 제31권7호
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• pp.643-649
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• 2014

In order to demonstrate the possibility of applying an ionic polymer metal composite (IPMC) to a finger exoskeleton, pinching motion analysis was performed for a thumb-index finger dummy actuated by IPMC actuators. The IPMC actuators of 5mm in width and 40mm in length with 2.4mm thickness generated 1.52N of blocking force for the applying voltage of 4.0V. Three actuators were installed on the three rotary joint of an index finger, and one actuator was installed on one proximal joint. Positions of each joint and finger tip were recorded on the video camera, and motion was analyzed. Power supply to the index finger actuators preceded power supply to the thumb actuator, and key pinching motion was accomplished in 180s. Tip pinching was accomplished in 135s as power supply to the thumb preceded power supply to the index finger.

• 한국약용작물학회지
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• 제15권2호
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• pp.128-131
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• 2007

This study was carried out to investigate inhibitory effect of extracts from Artemisia capillaris Thumb. on maltase, sucrase, ${\alpha}-amylase$, nonspecific ${\alpha}-glucosidase$, and postprandial hyperglycemia. Methanol extract and organic solvent (n-hexane, ethyl acetate, butanol, aqueous) fractions from the medicinal herb were determined for the inhibitory activities against maltase, sucrase and ${\alpha}-amylase$. The methanol extract from A. capillaris strongly inhibited maltase (57%) and ${\alpha}-glucosidase$ (72%) at the concentration of 100 ${\mu}g/m{\ell}$. Among the four fractions (n-hexane, ethyl acetate, butanol, aqueous) examined, the butanol fraction from A. capillaris showed potent inhibitory effects on maltase (73%), sucrase (33%), and ${\alpha}-amylase$ (75%) at the concentration of 100 ${\mu}g/m{\ell}$. The butanol fraction from Artemisia capillaris also exhibited significant reductions (20%) of blood glucose elevation in mice loaded with maltose. These results suggest that the extract from Artemisia capillaris can be used as a new nutraceutical for inhibition on postprandial hyperglycemia

• 한국산림과학회지
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• 제3권1호
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• pp.15-17
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• 1963

1) An experiment was made at the newly constructed glass house of Chun chan Agriculture callege to find out facts about the late-raising of Cortinellus edodes (Berk) Ido et Imai during the winter season. 2) The host timbers used in this experiment were Quercus Serrata Thumb and Quercus crispulo BI.; 5 years old each, the diameter ranging from 6cm to 17cm, dividing them into 12 diameter groups with 10 timbers in each group. The total number of timbess was 240 in two blocks. 3) As the pre-treatment of host timber, the autumn generation in 1962 was inhibited, and before being put into the glass-house, they were stimulated of generation for 3 days after 3 days, water-soaking. 4) The temperature control was made by using two coal stoves and the humidity control by spraying and two full water tanks. During cloudy weather and night, the green house was covered to preserue constant temperature of $5^{\circ}C{\sim}10^{\circ}C$. 5) The result; Quercus Serrata Thumb. with lesser diameter than 9cm showed no generation either in as big timber as one with diameter 11 cm. On the other hand, too big timbers showed low rate of generation; the reason, at a guess, is the too short period of cultivation and insufficient water soaking and inappropriate temperature. 6) The most standard size of host timber was found out be those with diameter 12cm~15cm in Quercus serrata Thumb, and those with diameter 14cm~17cm in Quercus crispula BI. Quercus crispula seemed to have slightly greater efficiency of generation than Quercus Serrata Thumb., but it could not be concluded as "decisive". Lastly, the host timber used in this experiment were old and the rate of generation was low as a whole.

• 한국컴퓨터정보학회논문지
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• 제25권7호
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• pp.151-157
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• 2020

본 연구는 1인 구조자 영아 심폐소생술 방법에 따른 효율성을 알아보기 위한 연구이다. 일반인 51명을 대상으로 일반적인 두 손가락을 이용한 방법과 새로운 방법인 머리 위 양손 감싼 두 엄지 가슴압박 방법으로 심폐소생술을 비교하였다. 두 심폐소생술 방법을 비교하기 위하여 SPSS 22.0을 이용하였다. 연구결과 머리 위 양손 감싼 두 엄지 가슴압박법이 평균 가슴압박의 깊이(39.38±1.07 mm)가 유의하게 깊게 나타났고(p<0.001), 인공호흡의 용이성(p<0.001), 방법의 편리성( p<0.001), 손가락 통증 정도(p<0.001)도 유의한 차이를 보였다. 그리고 심폐소생술 방법의 선호도는 80.4%(41명)가 머리 위 양손 감싼 두 엄지 가슴압박 방법을 이용한 심폐소생술을 선호하였다. 이 연구는 마네킨을 이용한 가상연구이기 때문에 향후 질 높은 심폐소생술 방법을 현장에 적용하기 위해 추가적인 연구가 필요할 것이다.

• 한국운동역학회지
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• 제22권2호
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• pp.253-259
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• 2012

The purpose of this study was to determine how smartphone use posture affects biomechanical variables and muscle activities. Eleven university students(age: $22.2{\pm}2.6$ yrs, height: $176.6{\pm}4.7$ cm, weight: $69.5{\pm}7.5$ kg) who have no musculoskeletal disorder were recruited as the subject according to having experience in using the smartphone for more than one year. Angular velocity, muscle activity, and thumb finger pressure were determined for each trial. For each dependent variable, a one-way analysis of variance (ANOVA) with repeated measures was performed to test if significant difference existed among different three conditions (p<.05). The result showed that rotational angular velocity of the first metacarpal were increased in DESK posture compared with STAND posture during SU phase. The average nEMG values of FDI(First dorsal interosseous) were less in SIT and DESK posture compared with STAND posture during SR phase. These indicated that smartphone postures may effect the thumb ROM(Range of motion) and muscle activity. This has led to suggestions of the need for further kinetic and EMG analyses to evaluate best assess and characterize with smartphone use.