• 제목/요약/키워드: A/E

검색결과 67,097건 처리시간 0.07초

식이중의 Vitamin A와 E가 Adriamycin을 투여한 흰쥐의 심근손상의 원인인 과산화작용에 미치는 영향 (Effect of Dietary Vitamin A and E Peroxidative Deterioration of Heart in Adriamycin-Treated Rats)

  • 정영아
    • Journal of Nutrition and Health
    • /
    • 제25권5호
    • /
    • pp.379-388
    • /
    • 1992
  • The present study was designed to evaluate the protective effects of dietary vitamin A or E. and of combination of vitamins A and E on peroxidative deterioration of heart in adriamycin-treated rats. Male Sprague-Dawley rats were assigned to 5 groups according to the dietary supplementation of vitamin A or E Except control rats a dose of 2mg ADR/kg of B. W was injected to these animals intraperitoneally on the same day every week. Adriamycin treatment significantly decreased the weight gain of experimental rats compared with that of control rats, But this decrement was not modified by dietary supplementation of vitamin A or E. Lipid peroxide values of plasma were elevated by ADR treatment. The combined use of ADR and dietary vitamin A or E significantly reduced these values, The interaction between vitamins A and E seemed to be present in the lipid peroxide value of plasma. Catalase and superoxide dismutase(SOD) activities in rat heart were decrased by ADR treatment but glutathione peroxidase(GSH-Px) activity was elevated. Dietary supplmen-tation of vitamin A or E enhanced the heart catalase and SOD activities. except only vitamin A-supplemented group. GSH-Px activity of rat heart tended to be decreased by dietary supple-mentation of vitamin A or E. With ADR treatment polyunsaturated fatty acids such as archido-nic acid(20:4) and docosahexaenoic acid(22:6) were decreased in rat heart. However dietary supplementation of vitamins A and E reduced this decrease. The retinol and tocopherol contents of rat plasma were decreased by ADR treatment. Dietary vitamin A or E influence vitamin A or E content of plasma. The interaction between dietary vitamins A and E was observed in vitamin A or E level of rat plasma.

  • PDF

저비용 항공사의 웹사이트 품질, e-만족, e-신뢰, e-충성도 간의 구조적 관계 연구 (The Relationships of Website Quality, e-Satisfaction, e-Trust, and e-Loyalty in Low-Cost Carriers)

  • 인옥남;김승리
    • 한국컴퓨터정보학회논문지
    • /
    • 제18권10호
    • /
    • pp.207-216
    • /
    • 2013
  • 최근 정보통신기술의 발달로 대부분 웹사이트의 외관과 디자인이 훌륭하게 제작되고, 이용도 손쉽게 할 수 있도록 제작되고 있다. 특히 저비용 항공사에서는 웹사이트의 품질이 고객의 항공기 예약과 구매에 직결되기 때문에 웹사이트 품질이 고객의 충성도에 중요한 요인으로 작용하게 된다. 저비용 항공사에 대한 고객의 충성도는 긍정적 구전과 재구매와 직결되기 때문에 웹사이트 품질향상에 많은 노력이 필요하다. 본 연구는 저비용 항공사 웹사이트 품질의 속성을 도출하고, 웹사이트 품질이 e-만족, e-신뢰, e-충성도에 영향을 미치는지에 대해서 검증하였다. 또한 e-만족, e-신뢰, e-충성도의 영향 요인을 검증하였다. 가설검증결과 저비용 항공사의 웹사이트 품질, e-만족, 그리고 e-신뢰는 e-충성도에 유의한 영향을 미치고, 웹사이트 품질은 e-만족과 e-신뢰에 유의한 영향을 미치는 것으로 연구되었다. 하지만 e-만족은 e-신뢰에 영향을 미치지 않는 것으로 연구되었다.

유기산 생성균에 의한 병원성 Escherichia Coli $A_2$와 Escherichia Coli $G_7$의 생육억제 (Growth Inhibition of Enteropathogenic Escherichia coli $A_2$and Escherichia coli $G_7$ by the Organic Acid Producing Bacteria)

  • 백영진;배형석
    • 한국미생물·생명공학회지
    • /
    • 제16권2호
    • /
    • pp.111-118
    • /
    • 1988
  • 유기산 생산균인 L. casei Y, Str. faecium C, Str. faecalis, Cl. butyricum M, B. toyoi를 사료첨가제와 발효유로부터 분리 확인하여 이들 균주가 자돈의 대장균증 설사를 유발시키는 E. coli $A_2$, E. coli G$_7$에 대하여 in vitro에서는 어떤 항균효과를 나타내는지 조사한 결과를 요약하면 다음과 같다. 1. L. casei Y, Str. faecium C, Str. faecalis, B. toyoi Cl. butyricum M을 각각 배양한 BL broth 3일 배양액은 모두 E. coli $A_2$와 E. coli G$_7$에 대하여 항균효과를 나타내었고, 이들 배양액을 E. coli $A_2$와 E. coli G$_7$에 대한 발육 Disc 확산시험 결과 그 저지환 직경은 각각 15mm와 17mm, 14mm와 15mm, 13mm와 14mm, 11mm와 13 mm, 10mm와 12mm 였다. 2. 유기산 생산 능력이 우수한 균일수록 E. coli $A_2$와 E. coli G$_7$에 대한 항균력이 높게 관찰되었으며, L. casei Y와 Str. faecium C가 이들 두 대장균에 대하여 높은 항균력을 나타내었다. 3. 유기산 생성균과 대장균(E. coli $A_2$, E. coli G$_7$)을 BL broth 에 혼합 배양할 때 E. coli $A_2$와 E. coli G$_7$은 배양액의 pH가 5.0 이하일 때 생육억제 되었고, pH 4.5 이하였을 때 사멸되었다. 4. 생성된 유기산은 배양액의 pH를 저하시킴과 동시에 항균성 물질로 직접 작용하여 E. coli $A_2$와 E. coli G$_7$의 생육저해 또는 사멸을 유도하였다. 5. E. coli $A_2$가 E. coli G$_7$보다 유기산 생산균의 대사산물에 대하여 더 높은 내성을 갖고 있었다.

  • PDF

Agrobacterium tumefaciens A348에서 virE 프로모터의 활성 (Activity of virE promoter in Agrobacterium tumefaciens A348)

  • 음진성
    • Journal of Plant Biology
    • /
    • 제34권4호
    • /
    • pp.331-339
    • /
    • 1991
  • To elucidate the regulatory mechanism of virE operon from vir regions (virA, virB, virC, virD, virG, virE) of pTiA6 which have been known to be essential for efficient crown gall tumorigenesis in plants, the activity of the truncated virE, promoter was analyzed. pSM358cd, a recombinant plasmid in which virE :: Tn3-HoHo1 (Tn3-promoterless lacZ) was cloned into SalI site of pVK102, was digested with SalI, and virE :: Tn3-HoHo1 was seperated from pVK102. To construct the truncted virE recombinant plasmids (pJS031, pJS051, pJS102, pJS201, pJS301), 5'-end of vireE promoter was deleted with BAL31 and cloned into pVK102 and then transferred into a. tumefaciens A348(pTiA6). According to the activity of the truncated virE promoter in recombinant plasmids, they were classified into two groups, pJS031, pJS051, pJS101 and pJS201 belong to a functional group and pJS301 is a non-functional. The size of deleted nucleotides of pJS201 and pJS301 seemed to be about 130 nucleotides and about 250 nucleotides from 5'-end of virE promoter, respectively. Hence it was thought that the essential site of the virE promoter was located between about 130th nucleotide and 250th nucleotide from 5'-end of the virE promoter.

  • PDF

Alteration of Lipid Metabolism by Ginseng Supplements With Different Levels of Vitamin E in High Cholesterol-Fed Rats

  • Do, Kyung-Min;Park, Yong-Bok;Bok, Song-Hae;Lee, Mi-Kyung;Jeong, Tae-Sook;Choi, Myung-Sook
    • Preventive Nutrition and Food Science
    • /
    • 제6권1호
    • /
    • pp.66-72
    • /
    • 2001
  • Ginseng may have antioxidant and pharmacologic effects similar to those of vitamin E. The interactive effect of ginseng and vitamin E was studied with respect to cholesterol metabolism and the antioxidant status. A ginseng supplement (0.1%, wt/wt) with comparable levels of vitamin E was provided with a high-cholesterol (1%, wt/wt) diet to rats for 5 weeks. The amount of vitamin E included in the ginseng-free and ginseng diets was either a low (low-E) or a normal (normal-E) level. The ginseng supplements significantly (p<0.05) altered the concentrations of plasma triglycerides in both the low-vitamin E group and normal-vitamin E group compared to the each ginseng-free group. The hepatic triglyceride and cholesterol content were not significantly (p>0.05) different between groups regardless of the vitamin E level in the diet. The hepatic HMG-CoA reductase activity was significantly (p<0.05) lowered by the ginseng supplement in both the low-vitamin E and the normal-vitamin E groups compared to the ginseng-free group. The HMG-CoA reductase activity was also significantly (p<0.05) lowered with in increase of the dietary vitamin E in the ginseng-free group. The excretion of fecal neutral sterol was significantly (p<0.05) lower in the normal-E ginseng group than th low-E ginseng-free group. Neither dietary ginseng nor vitamin E significantly changed the hepatic antioxidant enzymes activity. This data indicates that ginseng supplements lower the concentration of plasma triglyceride and hepatic HMG-CoA reductase activity regardless of eh dietary vitamin E level. This information may contribute to understanding the interactive effect of ginseng and vitamin E on cholesterol biosynthesis in high cholesterol-fed rats.

  • PDF

비타민 E 수준을 달리한 어유 또는 대두유를 먹인 흰쥐 조직의 지질과산화와 비타임 E 및 A 상태 (Lipid Peroxidation and Vitamins E and A Levels in Tissues of Rats Fed Fish Oil or Soybean Oil Supplemented with Vitamin E)

  • Choi Yong-Sun
    • Journal of Nutrition and Health
    • /
    • 제28권10호
    • /
    • pp.967-975
    • /
    • 1995
  • To investigate effects of dietary fish oil and vitamin E level on the tissue levels of vitamin E and vitamin A and to see which tissue is sensitive to lipid peroxidizability, male Sprague-Dawley rats were fed experimental diets composed of either menhaden oil or soybean oil nad either low(equivalent to 17 mg $\alpha$-tocopherol) or high (equivalent to 140mg $\alpha$-tocopherol) vitamin E level for 4 weeks. Palsma TBARS per mg lipid was significantly elevated in rats fed fish oil with low vitamin E level compared to soybean oil-fed rats. TBARS levels of liver, heart, kidney and liver microsomes were also increased by feeding fish oil with low vitamin E level. Plasma TBARS level was significantly correlated with TBARS levels of liver, heart, kidney and liver microsome. Plasma vitamin E level of groups with vitamin E supplementation was elevated significantly as compared to the those without vitamin E supplementation, whereas vitamin E levels of liver, heart and kidney were not changed significantly. Plasma TBARS was negatively correlated with plasma vitamin E(r=0.5763, P<0.001) and A(r=-0.4523, P<0.01) and seems to be a good indicator of in vivo lipid peroxidative stress.

  • PDF

Distribution of Vancomycin-resistant Enterococci Isolates Using a ChromID VRE Agar

  • Lee, Hyun;Yoon, In-Seon
    • 대한임상검사과학회지
    • /
    • 제45권1호
    • /
    • pp.1-4
    • /
    • 2013
  • Vancomycin-resistant enterococci (VRE) have emerged as important healthcare-associated infection since last two decades. ChromID VRE agar (cIDVA) is useful for VRE rectal swab screening. We investigated all VRE were isolated on the cIDVA. A total of 363 rectal swabs of 85 patients to test VRE screening were inoculated into bile-esculin (B-E) broth with $6{\mu}g/mL$ vancomycin. After 24 hours incubation, we subcultured B-E broths were changed to black onto cIDVA. All isolates were identified by the MICROSCAN and VITEK2. The vanA gene and vancomycin minimal inhibition concentration (MIC) were detected by PCR and E-test respectively. 277 E. faecium (84.7%), 16 E. faecalis (4.9%), 25 E. avium (7.6%), 8 E. gallinarum (2.4%) and 1 E. raffinosus (0.3%) were isolated. 10.3% of VRE detected on cIDVA were other than E. faecium and E. faecalis that presented various color from colorless to pale violet. All isolates contained vanA and vancomycin MIC were > $256{\mu}g/mL$. VRE isolates other than E. faecium and E. faecalis should be objective to the contact precautions for healthcare-associated infection control if they possess vanA gene. Due to emerging enterococci carrying vanA such as E. avium, E. gallinarum, and E. raffinosus, VRE surveillance should be expanded to all isolates on chromogenic agar.

  • PDF

Morphological and genetic diversity of Euglena deses group (Euglenophyceae) with emphasis on cryptic species

  • Kim, Jong Im;Linton, Eric W.;Shin, Woongghi
    • ALGAE
    • /
    • 제31권3호
    • /
    • pp.219-230
    • /
    • 2016
  • The Euglena deses group are common freshwater species composed of E. adhaerens, E. carterae, E. deses, E. mutabilis, and E. satelles. These species are characterized by elongated cylindrical worm-like cell bodies and numerous discoid chloroplasts with a naked pyrenoid. To understand the cryptic diversity, species delimitation and phylogenetic relationships among members of the group, we analyzed morphological data (light and scanning electron microscopy) and molecular data (nuclear small subunit [SSU] and large subunit [LSU] rDNAs and plastid SSU and LSU rDNAs). Bayesian and maximum likelihood analyses based on the combined four-gene dataset resulted in a tree consisting of two major clades within the group. The first clade was composed of two subclades: the E. mutabilis subclade, and the E. satelles, E. carterae, and E. adhaerens subclade. The E. mutabilis subclade was characterized by a lateral canal opening at the anterior end and a single pellicular stria, whereas the E. satelles, E. carterae, and E. adhaerens subclade was characterized by an apical canal opening at the anterior end of the cell and double pellicular striae. The second clade consisted of 20 strains of E. deses, characterizing by a subapical canal opening at the anterior end and double pellicular striae, but they showed cell size variation and high genetic diversity. Species boundaries were tested using a Bayesian multi-locus species delimitation method, resulting in the recognition of five cryptic species within E. deses clade.

e-비즈니스 채택요인과 성과에 관한 대기업과 중소기업의 차이분석 (A Comparative Analysis on the e-Business Adoption Factors and Performance in Large and Small Companies)

  • 이동만;안현숙;김효정
    • 한국정보시스템학회지:정보시스템연구
    • /
    • 제17권4호
    • /
    • pp.157-180
    • /
    • 2008
  • The majority of studies was undertaken on large companies that had adopted e-Business or on the specific case of dot.com companies. However, despite this interest in the effect of the size of an organization on its approach to e-Business, little direct comparison has been undertaken between small and large companies. This study examined the differences of e-Business adoption factors and e-Business performance between large and small companies. Reviewing the literature, we suggest a research model and develop nine hypotheses to be tested. Data are collected from 109 companies Implemented e-business. The results of hypothesis testing show as follows. First, e-Business performance of efficiency has a positive influence of perceived e-Business advantage, top management support, organizational learning ability and financial slack. Second, e-Business performance of sales performance has a positive influence of top management support. Third, e-Business performance of customer satisfaction has a positive influence of technology competence, perceived e-Business advantage, top management support, financial slack and institutional pressure. Finally, there are differences in the e-business factors(perceived e-Business advantage, top management support, institutional pressure) and e-Business performance(efficiency) between large and small companies.

동북아 e-Trade 활성화를 위한 e-ADR에 의한 분쟁해결에 관한 연구 (Dispute Resolution by e-ADR for e- Trade in the Northeast Asia)

  • 최석범;박종석;정재우
    • 한국중재학회지:중재연구
    • /
    • 제12권2호
    • /
    • pp.185-220
    • /
    • 2003
  • Korean Government is increasingly focusing on the Northeast Asia Business and Logistics Hub strategy to create a competitive advantage. A key element of this strategy is creating or leveraging distribution and logistics hubs that act as centres for distribution in Northeast Asia. A Northeast Asian e-Hub Policy is required for business hub and logistics hub in the Northeastern Asia. An e-Hub is an integrated, sophisticated set of e-Biz, information and e-trade facilities and services that provides access to a marketplace and exchangee the e-trade data. To study the e-Hub policy, Pan Asian e-Commerce Alliance, Korea-Japan e-Trade Hub project, and ASEM e-Trade project are considered. E-trade via cyberspace may need new methods of dispute resolution to reduce transaction costs for small value-related disputes and to erect structures that work well across national boundaries. Voluntary Mediation Councils and cyber tribunals should be encouraged by governmental sectors to continue developing private sector mechanisms to resolve e-trade disputes. Government-sponsored online cross-border dispute resolution systems may be also be useful to complement these private sector approaches. E-trade in Northeast Asia results in disputes owing to the incompleteness of e-trade law in the countries. These disputes contain disputes regarding e-trade model, central title registry, authentication body. To resolve these disputes in the Northeast Asia, a variety of electronic alternative dispute resolution bodies must be organized under cooperation of Korea, Japan, China. This study deals with the e-ADR construction in the Northeast Asia to resolve the disputes in the e-trade and to activate the e-trade in the Northeast Asia.

  • PDF