• 제목/요약/키워드: 7-deazaadenine

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7-데아자하이포크산틴과 7-데아자아데닌 유도체의 합성 (Synthesis of 7-Deazahypoxanthine and 7-Deazaadenine Derivatives)

  • 신관석;김남호;이주헌;성선영
    • 약학회지
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    • 제41권2호
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    • pp.181-186
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    • 1997

  • A series of 7-deazahypoxanthine and 7-deazaadenine derivatives[6,7.8.9.10,13] as purine antagonists was prepared. The pyrrolidine-5-one derivatives[4,11] were treated vith $(C_2H_5)_3OBF_4$ to give 3- aryl-5-ethoxy-2H-3,4-dihydropyrrole[5,12], which were converted to 7-aryl-7,8-dihydro-7(9H)-deazahy-poxanthine[6,7,8,9,10] and 7-phenyl-2-methyl-7,8- dihydro-7(9H)-deazaadenine[13].

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