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당말녕(糖末寧)을 위주(爲主)로 당뇨병(糖尿病)의 주위신경병변(周圍神經病變)을 치료(治療)하는 임상연구(臨床硏究)

  • 우세가
    • Journal of Haehwa Medicine
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    • v.5 no.2
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    • pp.501-501
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    • 1997
  • 당뇨병성(糖尿病性) 주위신경병변(周圍神經病變)은 당뇨병(糖尿病)에서 가장 많이 볼 수 있는 삼대합병증(三大合倂症) 중(中)의 하나이다. 환자(患者)의 임상표현(臨床表現)은 사고(四股) 및 구간부(軀幹部)가 마목(麻木)하고,동통(疼痛)이 칼로 베는 듯하거나 침(鍼)으로 찌르는 듯하여 참기 힘들며, 환자(患者)로 하여금 작업능력(作業能力)을 상실(喪失)하게 하고 휴식(休息)과 수안(睡眼)에 엄중(嚴重)한 영향(影響)을 준다. 지금까지 국내외(國內外)에서는 아직 효과적(效果的)인 치료방법(治療方法)이 없다. 우리는 임상(臨床)에서 관찰(觀察)해 본 결과(結果), 이 병(病)의 임상표현(臨床表現)인 "사고마목(四股麻木), 자통(刺痛), 야간가중(夜間加重), 통처고정(痛處固定)"의 특징(特徵)이 중의임상(中醫臨床)에서 표현(表現)되는 "혈어형(血瘀型)" 동통(疼痛)과 완전(完全)히 상동(上同)하였다. 우리는 "활혈화어(活血化瘀), 통락지통(通絡止痛), 거어생신(祛瘀生新)"을 치료원칙(治療原則)으로 중약복방(中藥復方) 제제(制劑) "당말녕(糖末寧)"을 제조(製造)하여 이 병(病)을 치료(治療)하는데 만족(滿足)스러운 임상치료효과(臨床治療效果)를 거두었다. 전체(全體)의 병례(病例)는 모두 우리 과(科)의 입원환자(入院患者)로써 모두 45례(例)인데, 병기(病機)에 따라 양조(兩組)로 나누었다. 관찰조(觀察組) 30례(例) 중(中)에는 남성(男性)이 19례(例)이고 여성(女性)이 12례(例)이며, 年齡(연령)은 25세(歲)에서 68세(歲)까지로 평균연령(平均年齡)이 49.8세(歲)이다. I형(型) 당뇨병(糖尿病)이 10례(例)이고 II형(型) 당뇨병(糖尿病)이 20례(例)이며, 당뇨병(糖尿病)의 병정(病程)은 6개월(個月)에서 17년(年)사이로 평균(平均) 7.1 년(年)이다. 주위신경병변(周圍神經病變)의 병정(病程)은 2주(周)에서 3년(年)까지로 평균(平均) 1년(年)이다. 대조조(對照組)는 15례(例)로 남성(男性)이 8례(例)이고 여성(女性)이 7례(例)이며, 연령(年齡)은 20세(歲)에서 65세(歲)까지로 평균(平均) 49세(歲)이다. I형(型) 당뇨병(糖尿病)이 7례(例)이고 II형(型) 당뇨병(糖尿病)이 8례(例)이며, 橋民病의 병정(病程)은 3개월(個月)에서 12년(年)까지로 평균(平均) 7.5년(年)이다. 주위신경병변(周圍神經病變)의 병정(病程)은 1개월(個月)에서 3년(年)까지로 평균병정(平均病程)은 11.6개월(個月)이다. 양조(兩組)사이의 병정(病程)은 현저(顯著)한 차이는 없으나 서로 비교(比較)해 볼만하다. 당말녕(糖末寧)은 주(主)로 삼궁(三芎),원호(元胡), 당귀(當歸), 계혈승 등(等)의 약물(藥物)로 조성(組成)되었고, 약제실(藥劑室)에서 濃縮液(농축액)(매(每) ml당(當) 생약량(生藥量) 2.5g 함유(含有))으로 제조(製造)하였다. 관찰조(觀察組)는 매차례(每次例) 당말녕(糖末寧) 50ml를 하루 세번씩 복용(服用)하였고; 대조조(對照組)는 비타민 $B_1$, 비타민 $B_6$을 각각(各各) 20mg씩 하루 세차례 복용(服用)하였다. 양조(兩組) 모두 사주(四周)를 한번의 치료료정(治療療程)으로 하였다. 우리는 모두 45례(例)의 환자(患者)를 관찰(觀察)하였는데, 그 중(中) 관찰조(觀察組)가 30례(例)이고 대조조(對照組)가 15례(例)이다. 임상표현(臨床表現) 분급(分級)과 신경근전도(神經筋電圖)(운동신경(運動神經)과 감각신경(感覺神經)의 전도(電圖) 속도(速度))를 치료(治療) 전(前)과 후(後)의 대조지표(對照指標)로 하였고. 매(每) 4주(周)를 한개의 료정(療程)으로 총(總) 1-2개(個)의 료정(療程)을 진행(進行)하여 比較硏究(비교연구)하였다. 총유효율(總有效率)은 96.7%이고 총현효율(總顯效率)은 50%로써 대조조(對照組)보다 뚜렷하게 높았다. 치료전(治療前) MNCV와 SNCV를 측정(測定)한 것은 당말녕(糖末寧)이 당뇨병(糖尿病) 주위신경병변(周圍神經病變) 환자(患者)의 신경전도속도(神經電圖速度)를 명확(明確)하게 개선(改善)하였음을 표현(表現)하고 있다. 신경근전도(神經筋電圖)에서 자발전위(自發電位)는 눈에 띄게 감소(減少)되고 소력수축(小力收縮)의 평균시한(平均時限)은 명확(明確)히 연장(延長)되었으며 다상전위(多相電位)는 명확(明確)하게 증가(增加)되었는데, 이는 신경지측(神經支測)이 재생(再生)되고 회복(恢復)하였음을 설명(說明)하고 있다. 중약복방제제(中藥復方制劑) "당말녕(糖末寧)"이 본병(本病)을 치료(治療)하는 기전(機轉)은 여러 방면(方面)일 것이다. 그 중(中) 微循環(미순환)을 개선(改善)하고 적혈구(赤血球)의 변형성(變形性)을 향상(向上)하여 신경세포(神經細胞)에 혈액(血液)과 산소공급(酸素供給) 및 영양공급(營養供給)을 향상(向上)함으로써 神經損傷(신경손상)의 수정(修整)과 회복(恢復)을 촉진(促進)하는 것이 주요(主要)한 일환(一環)이 될 것이다.

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Reconstruction of the Lower Extremities with the Gracilis Muscle Flap (박근 유리조직을 이용한 하지 재건술)

  • Lee, Jun-Mo;Lee, Ju-Hong
    • Archives of Reconstructive Microsurgery
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    • v.7 no.1
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    • pp.62-67
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    • 1998
  • The gracilis muscle is well suited to small and medium-sized soft tissue defects that cannot be adequately handled by simple rotational flaps and it will conform well to irregular contours, can be split longitudinally at both ends to allow cavities and awkwardly shaped spaces and can be transferred in part or in whole. The gracilis muscle used as a free muscle or musculocutaneous flap is small with a long, narrow contour and its vascular pedicle is a terminal branch of the medial femoral circumflex artery and vein. The aims of soft tissue reconstruction are to cover soft tissue defects, to clear up infection and to prepare for further surgical procedures. Authors have performed 12 gracilis muscle flaps in the lower extremities at Chonbuk National University Hospital from June 1994 through March 1998. The results were as follows. 1. 11 cases of 12(91.7%) were sustained from the crushing injury and secondary complications from the traffic accident. 2. The microsurgical anastomosis of one artery and two veins have performed in 6 cases(50%) of 12 and 11(91.7%) cases of 12 were successful at the third postoperative week and in the final result. 3. Gracilis muscle flap is the infetion-resistant and aesthetically acceptable performed in the lower leg 1/3 and the foot.

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Early Result of Surgical Management of the Anomalous Origin of the Left Coronary Artery from the Pulmonary Artery (관상동맥-폐동맥 이상 기시증에 대한 수술의 조기 결과)

  • Yoon Yoo Sang;Park Jeong Jun;Yun Tae Jin;Kim Young Hwue;Ko Jae Kon;Park In Sook;Seo Dong Man
    • Journal of Chest Surgery
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    • v.39 no.1 s.258
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    • pp.18-27
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    • 2006
  • Background: Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) is a rare congenital anomaly, but is one of the most common causes of myocardial ischemia which would result in high mortality within the first year of life. This is our early result of the surgical management for these patients. Material and Method: From June 1989 to July 2003, 6 patients with ALCAPA and one patient with ARCAPA (Anomalous origin of the Right coronary artery from the pulmonary artery) underwent surgical repair. We have reviewed the all medical records, electrocardiogram, chest X-ray and echocardiography retrospectively. Result: Three of the patients were boys and four were girls. The median age at the operation was 5.4 months (Range: 3$\∼$33 months). The average body weight of at the operation was 6.7 kg (Range: 3.7$\∼$11.3 kg). A mean follow up period was 18 months. Only 3 patients were initially diagnosed as ALCAPA. And 3 patients had moderate mitral regurgitation. Immediate coronary artery reimplantation on diagnosis with the aim of restoring a two-coronary system circulation was done. The average bypass time was 114$\pm$37 minutes, and the average aortic cross clamping time was 55$\pm$22 minutes. The average stay of intensive care unit was 5$\pm$3 days, the mean mechanical ventilator time was 38$\pm$45 hours and the hospital stay after operation was 12$\pm$5 days. There were significant improvements in electrocardiogram and chest X-ray of the all patients except one late death patient. The ventricular function showed almost normal recovery after operation; the EF (Ejection Fraction) increased from 41.2$\pm$ 10.3$\%$ to 60.5$\pm$ 15.8$\%$ within 1 month and to 59.8$\pm$13.9$\%$ within 1 year after operation, the SF (Shortening Fraction) increased from 23.6$\pm$4.7$\%$ to 38.6$\pm$8.4$\%$ within 1 month and to 37.4$\pm$7.9$\%$ within 1 year after operation, LVEDDI (Left Ventricular End-diastolic Dimension Index) decreased from 100.8$\pm$25.6 mm/$m^{2}$ to 90.3$\pm$ 19.2 mm/$m^{2}$ within f month and to 79.3$\pm$ 15.8 mm/$m^{2}$ within 1 year after operation. Concomitant mitral repair was done in two patients with anterior mitral leaflet prolapse. In every patient, mitral valve showed less than mild regurgitation during follow up. One late death occurred in which patient Dor procedure was applied 10 months after initial operation due to the dilated cardiomyopathy Conclusion: In the management of this rare and could be fatal Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA), early suspicion and correct diagnosis is of most important. But, after diagnosis, immediate restoration of 2 coronary systems could result in good outcome.

Postoperative Pulmonary Vein Stenosis (PVS) in Patients with TAPVR (전 폐정맥 환류 이상의 수술 후 폐정맥 협착에 대한 분석)

  • Jung Sung-Ho;Park Jeong-Jun;Yun Tae-Jin;Jhang Won-Kyoung;Kim Young-Hwue;Ko Jae-Kon;Park In-Sook;Seo Dong-Man
    • Journal of Chest Surgery
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    • v.39 no.5 s.262
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    • pp.347-353
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    • 2006
  • Background: Despite recent advances in surgical technique and perioperative care of total anomalous pulmonary venous return (TAPVR), post-repair pulmonary vein stenosis (PVS) remains as a serious complication. We thought that the most important factors of TAPVR repair to prevent PVS were good exposure, proper alignment, and sufficient stoma size. We analyzed our experience retrospectively. Material and Method: Between Jan. 1995 and Feb. 2005, we studied 74 patients diagnosed with TAPVR suitable for biventricular repair. Supra-cardiac type (n=41, 55.4%) was the most common. Mean CPB time, ACC time, and TCA (40.5%, 30/74) time were $92.1{\pm}25.9\;min,\;39.1{\pm}10.6\;min$, and $30.2{\pm}10.7\;min$, respectively. Mean follow-up duration was $41.4{\pm}29.1$ months and follow-up was possible in all patients. Result: The median age and body weight at operation were 28.5 days ($0{\sim}478$ days) and 3.4 kg $(1.4{\sim}9\;kg)$. Early mortality was 4.1% (3/74). Causes of death were pulmonary hypertensive crisis, sepsis, and sudden death. There was PR-PVS in 2 patients (early: 1, late: 1). Both patients were cardiac type TAPVR drained to coronary sinus. Re-operations were done but only one patient survived. Cumulative survival rate in 5 year and percent freedom from PVS were $94.5{\pm}2.7%\;and\;97.2{\pm}2.0%$, respectively. Conclusion: There was no PVS in patients who underwent extra-cardiac anatomosis between LA and CPVC. Therefore it could be said that our principle might be effective in preventing PR-PVS in patients suitable two-ventricle.

Logical architecture for hybrid library design (하이브리드 도서관 설계를 위한 논리적 구조)

  • 김지훈;노진구
    • Journal of the Korean Society for information Management
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    • v.19 no.2
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    • pp.69-92
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    • 2002
  • A hybrid information service may include local and/or remote distributed services, both and electronic. Also, a hybrid information service can be described as one which an appropriate range of heterogeneous information services is presented to the user in a consistent and integrated way via a single interface. The purpose of this study is to suggest high-level requirements and logical architecture to design hybrid library. High-level requirements analysis for hybrid library need to contain baseline requirements, basic system requirements, searching, location, requesting, delivery and payment. A logical architecture need to consider logical architecture for hybrid library management system including user access points, hybrid library management system and hybrid library components and 5 layered architecture including presenter, coordinator, mediator, communicator and provider to achieve local simplicity while still supporting complex functionality of hybrid library.

A Research on the Cloud Computing Security Framework (클라우드 컴퓨팅 정보보호 프레임워크에 관한 연구)

  • kim, Jung-Duk;Lee, Seong-Il
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.23 no.6
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    • pp.1277-1286
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    • 2013
  • Cloud computing's unique attributes such as elasticity, rapid provisioning and releasing, resource pooling, multi-tenancy, broad-network accessibility, and ubiquity bring many benefits to cloud adopters(company and organization), but also entails specific security risks associated with the type of adopted cloud and deployment mode. To minimize those types of risk, this paper proposed cloud computing security framework refered to strategic alliance model. The cloud computing security framework has main triangles that are cloud threat, security controls, cloud stakeholders and compose of three sides that are purposefulness, accountability, transparent responsibility. Main triangles define purpose of risk minimization, appointment of stakeholders, security activity for them and three sides of framework are principles of security control in the cloud computing, provide direction of deduction for seven service packages.

Extended GTRBAC Delegation Model for Access Control Enforcement in Enterprise Environments (기업환경의 접근제어를 위한 확장된 GTRBAC 위임 모델)

  • Hwang Yu-Dong;Park Dong-Gue
    • Journal of Internet Computing and Services
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    • v.7 no.1
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    • pp.17-30
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    • 2006
  • With the wide acceptance of the Internet and the Web, volumes of information and related users have increased and companies have become to need security mechanisms to effectively protect important information for business activities and security problems have become increasingly difficult. This paper proposes a improved access control model for access control enforcement in enterprise environments through the integration of the temporal constraint character of the GT-RBAC model. sub-role hierarchies concept and PBDM(Permission Based Delegation Model). The proposed model. called Extended GT-RBAC(Extended Generalized Temporal Role Based Access Control) delegation Model. supports characteristics of GTRBAC model such as of temporal constraint, various time-constrained cardinality, control flow dependency and separation of duty constraints (SoDs). Also it supports conditional inheritance based on the degree of inheritance and business characteristics by using sub-roles hierarchies and supports permission based delegation, user to user delegation, role to role delegation, multi-step delegation and temporal delegation by using PBDM.

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A Study on the Legal Bases for Plurality of Obligors and Obligees under PICC (국제상사계약에 관한 일반원칙(PICC)하에서 다수의 채무자와 채권자에 관한 법적 기준)

  • SHIM, Chong-Seok
    • THE INTERNATIONAL COMMERCE & LAW REVIEW
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    • v.72
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    • pp.1-24
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    • 2016
  • This study focused on getting clear understanding on the legal bases in terms of plurality of obligors and plurality of obligees through a analysis the PICC(2010) which has been standing firmly as the general principles of international commercial contract. Related to the title of this paper, PICC are dealing with not only plurality of obligors but plurality of obligees. The contents of the former are as follows; presumption of joint and several obligations and obligee's rights against joint and several obligors (arts.11.1.1, 11.1.2, 11.1.3), availability of defences and rights of set-off and effect of performance and set-off (arts.11.1.4, 11.1.5), effect of release or settlement and effect of expiration or suspension of limitation period (arts.11.1.6, 11.1.7), effect of judgment (art.11.1.8), apportionment among joint and several obligors and extent of contributory claim (arts.11.1.9, 11.1.10), rights of the obligee, defences in contributory claims, inability to recover (arts.11.1.11, 11.1.12, 11.1.13) and so on. On the other hand the contents of the latter are as follows; definitions (art.11.2.1), effects of joint and several claims (art.11.1.2), availability of defences against joint and several obligees (art.11.2.3), allocation between joint and several obligees (art.11.1.4). The main subjects are one is when several obligors are bound by the same obligation towards an obligee, the obligations are joint and several when each obligor is bound for the whole obligation, the obligations are separate when each obligor is bound only for its share and the other is when several obligees can claim performance of the same obligation from an obligor, the claims are separate when each obligee can only claim its share, the claims are joint and several when each obligee can claim the whole performance and the claims are joint when all obligees have to claim performance together.

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Music Teacher Education for Multicultural Music Education: An Analysis of Multicultural Contents in Undergraduate Music Education Curriculum in USA (다문화 음악교육을 위한 음악 교사 교육의 방향: 미국 음악교사 교육과정의 다문화 교과목의 분석을 통하여)

  • Lee, Ka-Won
    • The Journal of the Korea Contents Association
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    • v.13 no.7
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    • pp.473-483
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    • 2013
  • In the 21th century, world citizens have more chances to meet and interact with people from different cultural or ethnic backgrounds than ever before. It is therefore inevitable that multiculturalism has become one of the integral part of music education. Educators in every field should make conscious efforts to provide opportunities and experiences for students so that they can adequately cope with these culturally diverse encounters. This study is to grasp the current state of multicultural education in the teacher education program in Korea and America. Also it is aimed to figure out the current multicultural music course offerings available for undergraduate music education majors at the selected 10 American Universities. It is expected that this study may suggest an idea of multicultural-world music education in teacher education.

A Study on the Model for Construction Records Classification System (건설기록물 분류체계 모형에 관한 연구)

  • Park, Yong-Boo;Kim, Tae-Soo
    • Journal of the Korean Society for information Management
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    • v.28 no.3
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    • pp.83-101
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    • 2011
  • The international standards, ISO 15489 and Family Code, recommend using functional classification method both in public and private organizations. In this study made a comparative analysis of the details of classification systems through case studies on records classification systems of a total of seven comprehensive construction companies in Korea including three large corporations and four small and medium-size businesses. Findings of this study suggester the direction of developing construction records classification system and its methodology. By summarizing classification standards derived from these case studies, key construction records classification standards were presented.