• Title/Summary/Keyword: 6DoF

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Effect of Micronization on the Extent of Drug Absorption from Suspensions in Humans

  • Oh, Doo-Man;Rane L.Curl;Yong, Chul-Soon;Gordon L.Amidon
    • Archives of Pharmacal Research
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    • v.18 no.6
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    • pp.427-433
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    • 1995
  • A microscopic mass balance approach has hsown that the initial saturation (Is), absorption number (An), dose number (Do), and dissolution number (Dn) are four fundamental dimensionless parameters that can be used to estimate the fraction dose absorbed (F)l of suspensions of poorly soluble drugs in humans. The dissolution number of a drug increases with decreasing its particle size. The effect of micronization on F for suspensions was investigated in terms of Dn. About 90% of maximal F can be achieved at $Dn{\approx}2$. Increasing the solubility of a drug results in better oral absorption through increasing Dn and decreasing the solubility of a drug results in better oral absorption through increasing Dn and decreasing Do. The fractions dose absorbed of digoxin, griseofulvin, and benoxaprofen agree with predicted F values sorbed by reducing particle size, while absorption of drugs with high Do and low Dn is limited by solubility and requires higher solubility to enhance the fraction dose absorbed in addition to micronization. Solubility at the physiological pH should be used for the estimation of the fraction dose absorbed.

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Impedance Properties of Electroluminescent Device Containing Blended Polymer Single-Layer (고분자 블렌드를 이용한 EL 소자의 임피던스 특성)

  • 김주승;서부완;구할본;이경섭
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2000.07a
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    • pp.332-335
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    • 2000
  • We fabricated organic electroluminescent (EL) devices with single layer of poly(3-dodeoylthiophene) (P3DoDT) hlended with different amounts of poly(N-vinylcarbazole) (PVK) as a emitting layer. The molar ratio between P3DoDT and PVK changed with 1:0, 2:1 and 1:1. To improve the external quantum efficiency of EL devices, we applied insulating layer, LiF layer, between polymer emitting layer and Al electrode. All of the devices emit orange-red light and it's can be explained that the energy transfer occurs from PVK to P3DoDT. In the voltage-current and voltage-brightness characteristics of devices applied LiF layer, current and brightness increased with increasing applied voltage. The brightness of the device have a molar ratio 1:1 with LiF layer was about 10 times larger than that of the device without PVK at 6V. Electrical impedance properties of ITO/emitting layer/LiF/Al devices were investigated. In the Cole-Cole plots of impedance data, one semicircle was observed. Therefore, the equivalent circuit for the devices can be designed as a single parallel resistor and capacitor network with series resistor.

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A Study on the burnout of firefighters (소방대원의 소진(Burnout)에 관한 연구)

  • Lee, In-Soo;Choi, Eun-Sook
    • The Korean Journal of Emergency Medical Services
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    • v.4 no.1
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    • pp.47-55
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    • 2000
  • The study was conducted to investigate the burnout of firefighters. The subjects were 223 firefighters in C-Do. The instruments used for this study were a survey of general characteristics(10 items), burnout(23 items). Analysis of data was done by use of mean percentage, t-test, ANOVA, stepwise multiple regression with SAS program. The results of this study are as follows; 1. Burnout according to general characteristics were showed significant difference in job-aptitude(F=6.30, P<.001), health status(F=5.92, P<.001), education(t=6.09, P<.01), working place rotation(t=2.59, P<.01), call number/week(F=3.28, P<.01), job-burden(F=4.45, P<.01), paper-job burden(F=3.87, P<.05). 2. Category score of burnout were showed the higher score in the lowed personal accomplishment(3.29). 3. Category score of burnout according to aptitude were showed difference each other. 4. Predicting factor of burnout were paper-job burden, health status, job-burden(20.99%).

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Atmospheric Distribution of PCDD/F Concentrations in Gyeonggi-do, South Korea (경기도 내 대기 중 다이옥신 분포 특성에 관한 연구)

  • Heo, Jong-Won;Min, Yoon-Ki;Kim, Dong-Gi;Choi, Il-Woo;Kim, Jong-Soo;Song, Il-Seok;Lee, Gangwoong
    • Journal of Korean Society for Atmospheric Environment
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    • v.31 no.6
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    • pp.548-561
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    • 2015
  • Atmospheric concentrations of polychlorinated dibezo-p-dioxins and furans (PCDD/Fs) were investigated at urban-residential (Group I: Suwon, Guri and Goyang), industrial (Group II: Ansan, Siheung and Bucheon), urban-rural mixed (Group III: Yangju, Pocheon and Dongducheon) and rural regions (Group IV: Yangpyeong) in Gyeonggi-do from February 2012 to November 2012 quarterly. The concentrations of PCDD/Fs ranged from 0.018 to $0.109pgTEQm^{-3}$ in Group I (mean value: $0.061pgTEQm^{-3}$), 0.059 to $0.367pgTEQm^{-3}$ in Group II (mean value: $0.179pgTEQm^{-3}$), 0.072 to $0.836pgTEQm^{-3}$ in Group III (mean value: $0.334pgTEQm^{-3}$) and 0.014 to $0.066pgTEQm^{-3}$ in Group IV (mean value: $0.034pgTEQm^{-3}$), respectively. In spite of the less PCDD/F emission sources than Group II (industrial regions), the level of PCDD/Fs in urban-rural mixed area showed the highest values with high fluctuation. It's likely that the Group III was affected by fugitive emissions such like biomass burning and unregulated open burning. The mean contribution of particle phase to total PCDD/F concentration was above 83% because most of PCDD/F congeners were partitioned into particle phase. We evaluated their gas-to-particles equilibriums with the regression between the particle-gas partition coefficient, $K_P(m^3{\mu}g^{-1})$ and corresponding subcooled liquid vapor pressure ($P_L$). The logarithm-$K_P$ of PCDD/Fs was poorly correlated with $P_L$ at low ambient temperature (below $10^{\circ}C$) and the slope (m) values for log-log plots of the $K_P$ vs. $P_L$ was steeper in the Group 2 and Group 3 than residential area. It implies that the slope values were likely influenced by both the direct emission source of PCDD/Fs and ambient temperature.

The Analysis of Covariance of Do(province) Population Variability (한국 도별(道別) 인구수 변천에 대한 공분산분석(共分散分析))

  • Shin, Min-Wong
    • Journal of Preventive Medicine and Public Health
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    • v.6 no.1
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    • pp.77-79
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    • 1973
  • The Mechanism for sorting out the covariance effect is known as the covariance analysis. The sorting out of regression and correlation effect is an obvious application of the covariance analysis. The result of Do population by age groups (15 ages interval) from 1966 Census and from 1970 Census has been applied to analyzing covariability by the analysis of covariance. The results are as follows. (1) The signicance of the regression of 1970 population on 1966 population is assured as F=116.5 (2) There is a significant difference between mean of each age group. (F=88.1) (3) There is very little evidence of significant heterogeneity of regression between age groups. (F=0.72)

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Six-degree-of-freedom Manipulator Displacement Measurement using Stereo Vision (스테레오비전을 이용한 6자유도 머니퓰레이터 변위 측정)

  • Lee, Dong-Hyeok;Baek, So Young;Cho, Nahm Gyoo
    • Journal of the Korean Society for Precision Engineering
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    • v.32 no.2
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    • pp.191-198
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    • 2015
  • In this paper, six-degree-of-freedom (DoF). Displacement measurement technique using a compact stereo-vision system is proposed. The measuring system consists of a camera, an optical prism, two plane mirrors, and a planar marker on a target. The target was attached on an object so that its six-DoF displacement can be calculated using a proposed coordinates estimating algorithm and stereo images of the marker. A prototype was designed and fabricated for performance test. From the test results, it can be confirmed that the proposed measuring technique can be applied to monitoring and control of various manipulators.

Efficient Representation of Patch Packing Information for Immersive Video Coding (몰입형 비디오 부호화를 위한 패치 패킹 정보의 효율적인 표현)

  • Lim, Sung-Gyun;Yoon, Yong-Uk;Kim, Jae-Gon
    • Proceedings of the Korean Society of Broadcast Engineers Conference
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    • fall
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    • pp.126-128
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    • 2021
  • MPEG(Moving Picture Experts Group) 비디오 그룹은 사용자에게 움직임 시차(motion parallax)를 제공하면서 3D 공간 내에서 임의의 위치와 방향의 시점(view)을 렌더링(rendering) 가능하게 하는 6DoF(Degree of Freedom)의 몰입형 비디오 부호화 표준인 MIV(MPEG Immersive Video) 표준화를 진행하고 있다. MIV 표준화 과정에서 참조 SW 인 TMIV(Test Model for Immersive Video)도 함께 개발하고 있으며 점진적으로 부호화 성능을 개선하고 있다. TMIV 는 여러 뷰로 구성된 방대한 크기의 6DoF 비디오를 압축하기 위하여 입력되는 뷰 비디오들 간의 중복성을 제거하고 남은 영역들은 각각 개별적인 패치(patch)로 만든 후 아틀라스에 패킹(packing)하여 부호화되는 화소수를 줄인다. 이때 아틀라스 비디오에 패킹된 패치들의 위치 정보를 메타데이터로 압축 비트열과 함께 전송하게 되며, 본 논문에서는 이러한 패킹 정보를 보다 효율적으로 표현하기 위한 방법을 제안한다. 제안방법은 기존 TMIV10.0 에 비해 약 10%의 메타데이터를 감소시키고 종단간 BD-rate 성능을 0.1% 향상시킨다.

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Free view video synthesis using multi-view 360-degree videos (다시점 360도 영상을 사용한 자유시점 영상 생성 방법)

  • Cho, Young-Gwang;Ahn, Heejune
    • Proceedings of the Korea Information Processing Society Conference
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    • 2020.05a
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    • pp.600-603
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    • 2020
  • 360 영상은 시청자가 시야방향을 결정하는 3DoF(3 Degree of Freedom)를 지원한다. 본 연구에서는 다수의 360 영상에서 깊이 정보를 획득하고, 이를 DIBR (Depth -based Image Rendering) 기법을 사용하여 임의 시점 시청기능을 제공하는 6DoF(6 Degree of Freedom) 영상제작 기법을 제안한다. 이를 위하여 기존의 평면 다시점 영상기법을 확장하여 360 ERP 투영 영상으로부터 카메라의 파라미터 예측을 하는 방법과 깊이영상 추출 방법을 설계 및 구현하고 그 성능을 조사하였으며, OpenGL 그래픽스기반의 RVS(Reference View Synthesizer) 라이브러리를 사용하여 DIBR을 적용하였다.

Surveys of Gynaecotyla squatarolae and Microphallus koreana (Digenea: Microphallidae) Metacercariae in Two Species of Estuarine Crabs in Western Coastal Areas, Korea

  • Lee, Hye-Jung;Chai, Jong-Yil;Lee, Jin-Woo;Jin, Ho;Min, Kwan-Hong;Cho, Yong-Jun;Seo, Min
    • Parasites, Hosts and Diseases
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    • v.48 no.1
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    • pp.81-83
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    • 2010
  • To figure out the geographical distribution of Gynaecotyla squatarolae and Microphallus koreana metacercariae in Korea, shore crabs of southwestern coastal areas were examined. Eight coastal areas in Inchon-si (A), Gyeonggi-do (B), Chungcheongnam-do (C, D, and E), Jeollabuk-do (F), and Jeollanam-do (G and H) were selected, and 2 kinds of crabs, Macrophthalmus dilatatus and/or Macrophthalmus japonicus, were caught. After transportation to the laboratory, 15 crabs per each group were grouped and ground in a mortar and pestle, and examined for microphallid metacercariae. In M. dilatatus, G. squatarolae metacercariae were recovered from 3 (C, E, and H) out of 6 regions, but M. koreana metacercariae were not recovered. In the case of M. japonicus, G. squatarolae metacercariae were recovered from 6 (B, D, E, F, G, and H) of 7 areas surveyed, and M. koreana matacercariae were detected from 5 regions (A, B, D, F, and H). These results indicate that the life cycle of G. squatarolae is maintained in the western coastal areas using M. dilatatus and M. japonicus as intermediate hosts, while that of M. koreana is maintained only using M. japonicus.

Study of Death Attitudes by General Characteristics and Death Perceptions of the Severely Diseased Persons in Hospice Facilities -Focus in O City, Gyeonggi-do (호스피스 요양병원에 입원한 중증질환자의 일반적 특성과 인식도에 따른 죽음의 태도에 관한 연구 -경기도 O시 중심으로-)

  • Kim, Moon-Dol;Cho, Sung-Je
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.12
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    • pp.7148-7159
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    • 2014
  • This study examined the relationship between the death perceptions and attitudes of the severely diseased persons in hospice facilities based on their general characteristics. The surveys were conducted from March 10 to July 31, 2013 on 149 patients at hospice facilities in ${\bigcirc}$ city, Gyeonggi-do. The data was analyzed by the SPSS WIN 18.0. First, positive death attitudes showed significant differences according to the patients' general characteristics (F=6.218, p<.001). Second, the patients' death attitudes by their death perceptions showed meaningful results (F=6.634, p<.001). Third, the death attitudes revealed a positive relation with hospice use (r=.496, p<.001). Overall, patients, who have positive death perceptions and attitudes, have high expectations for hospice use and these results support for welfare policies to encourage hospice use of severely diseased persons.