• 생약학회지
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• 제19권1호
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• pp.34-38
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• 1988

Veronicastrum species are perennial herb growing on the moisty land. They involves on species (V. sibiricum, Naeng-Cho), one subspecies (V. sibiricum var. zuccarini, Tuel-Naeng-Cho) and one variety (V. sibiricum var. zuccarini for. albiflora). This paper deals with a comparison of the chemical components between Naeng-Cho and Tuel-Naeng-Cho.) In the specified HPLC condition used with ${\mu}BondapakC_{18}\;column$, the retention time of aucubin, catalpol, minecoside and veratryl catalpol ester were 2.30, 2.65, 3.05 and 3.10 min, respectively, and in the other condition used with ${\mu}Bondapak\;C_8-NH_2$, the retention time of aucubin, catalpol, minecoside and veratryl catalpol were 5.4, 5.4, 4.4 and 3.2 min, respectively. The contents of minecoside in Tuel-Naeng-Cho were found to be 3.5 and 1mg/g of dry plant material and that of catalpol were found to be 5 and 2 mg/g, respectively.

• 생약학회지
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• 제18권3호
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• pp.168-176
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• 1987

Veronicastrum sibiricum (L.) Pennell (Scrophulariaceae) is a perennial herb growing in moist land. It has been used as a korean folk medicine in treating common cold, leucorrhea, cystitis and liver damage and as cholagogue. The present study dealt with the elucidation of the chemical components. From the roots of the plant, five iridoids were isolated and identified as minecoside $(mp\;142{\sim}3^{\circ})$, 6-O-veratryl catalpol ester $(mp\;216{\sim}8^{\circ})$, catalpol $(mp\;204{\sim}6^{\circ})$, aucubin $(mp\;180{\sim}2^{\circ})$ and 6-desoxy-8-isoferuloyl harpagide $(mp\;139{\sim}41^{\circ})$. Furthermore, ${\beta}-sitosteryl-3-O-D-glucoside$, campesteryl 3-O-D-glucoside, ${\beta}-sitosterol$, campesterol, stigmasterol and mannitol were also isolated.