• Title/Summary/Keyword: 6,$7-dihydroxy-4-methoxy-{\delta}-lactone (8-hydroxybergapten)$ and 5-benzofuranacrylic

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Promoting Synthesis of Collagen from Angelica dahurica Root (백지의 콜라겐 생성 촉진 물질)

  • Jung, Min-Hwan;Lim, Young-Hee;Lee, Sang-Hwa;Kang, Sang-Jin;Cho, Wan-Goo;Jin, Mu-Hyun
    • Korean Journal of Pharmacognosy
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    • v.35 no.4 s.139
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    • pp.315-319
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    • 2004
  • Three coumarin derivatives, which stimulate collagen biosynthesis in human fibroblasts were isolated from Angelica dahurica root which has been used in traditional medicine for cold, headache, discharging blood and women's diseases. Three coumarin derivatives were identified as 5-benzofuranacrylic acid, $6,7-dihydroxy-4-(3-methyl-2-butenyl)-{\delta}-lactone\;(prangenidin)$, 5-benzofuranacrylic acid, $6,7-dihydroxy-4-methoxy-{\delta}-lactone\;(8-hydroxybergapten)$ and 5-benzofuranacrylic acid, 8-hydroxypsoralen(xanthotoxol) from their spectral data.