• Title/Summary/Keyword: 5-108

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Analysis of HPV Prevalence in Pairs of Cervical and Urine Samples from the Same Woman

  • Kim, Dong Hyeok;Jin, Hyunwoo;Lee, Kyung Eun
    • Biomedical Science Letters
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    • v.27 no.1
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    • pp.28-34
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    • 2021
  • The main cause of cervical cancer is a persistent infection with high-risk human papillomavirus (HR-HPV). Cervical cancer is reported as a preventable cancer in more than 80% of cases with early diagnosis and appropriate treatment. Papanicolaou test (Pap test) has been a global strategy to prevent cervical cancer, and recently, HPV test has been reported to be effective against cervical cancer and precancerous lesions. However, pelvic examinations give patients anxiety, discomfort, pain, distress, and psychological stress. HPV test via a urine sample caused less physical and psychological stress and more advantage than the Pap test. Therefore, it is necessary to study the usefulness of the HPV test for easy-to-collect urine samples. A total of 220 samples were collected from a pair of cervical and urine samples from 110 women and only 108 pairs of samples out of 110 were used because 2 cases were not amplified by β-globin. Among 108 pairs of cervical and urine samples, the prevalence of HPV was 37.0% (40/108) in cervical samples, 34.3% (37/108) in urine samples and HR-HPV was 22.2% (24/108) in cervical samples, 18.5% (20/108) in urine samples. In this study, urine samples showed a lower positive rate of HPV than cervical samples. There were many variables that could affect the condition of the urine sample. However, the HR-HPV agreement rate of the cervix and urine samples was 94.44% and the Kappa value was 0.823, which was "almost perfect". Through these results showed the significance of cervical cancer screening using a urine sample. Cervical screening is crucial, as cervical cancer can be prevented in more than 90% of cases. Urine samples collected by non-invasive methods may have the potential advantage of increasing acceptance of cervical cancer screening. Therefore, it is necessary to develop a new cervical cancer screening strategy using urine samples through further study based on the results of this study.

Decomposition of Guanosine-5’-Monophosphate by Heat Treatment (구아닌 산의 열(熱) 분해(分解)에 관(關)한 연구(硏究))

  • Lee, Jae-Heung;Ko, Jung-Hwan;Kim, Hong-Jip;Bae, Jong-Chan;Yu, Ju-Hyun
    • Korean Journal of Food Science and Technology
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    • v.11 no.3
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    • pp.188-191
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    • 1979
  • The heat decomposition rate of guanosine-5'-monophosphate was investigated in pH range from 5.52 to 7.00, and 0.1 of the ionic strength. The result showed that the rate was a first-order reaction and the rate of guanosine-5'-monophosphate loss was maximum near $pKa_2$. The loss of guanosine-5'-monophosphate was temperature dependent and followed to the Arrhenius equation in the temperature region from $93^{\circ}C$ to $108^{\circ}C$. The rate constant as function of temperature ($93^{\circ}C$ to $108^{\circ}C$) and neutral pH($pKa_2$, 6.0, to 7.0) was correlated by least-square fit of the experimental data; $$K=4.19{\times}10^{26}\;{\exp}\;[-1.3(pH+E/RT)]$$

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The Clinical and Pathological Study of Laryngeal Mass (후두종양의 임상적 및 병리학적 고찰)

  • 이원용;배정수;김혜숙;여재동;조세인
    • Proceedings of the KOR-BRONCHOESO Conference
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    • 1983.05a
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    • pp.6.2-6
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    • 1983
  • The clinical study of 108 laryngeal mass was observed in our E.N.T. department, and classified clinically and pathologically as below. 1) Among total case of 108 Vocal nodule is 28 (26 %) Vocal polyp is 46 (42.5 %) Laryngeal papilloma is 6 (5.5 %) Laryngeal tuberculosis is 4 (4%) Laryngeal cancer is 24 (22%) 2) The sex ratio of male to female is 5 : 7 in vocal nodule 11 : 12 in vocal polyp 1 : 1 in laryngeal papilloma 3 : 1 in laryngeal tuberculosis 5 : 1 in laryngeal cancer 3) The age distribution is fourth, fifth decade in vocal nodule is fifth, fourth decade in vocal polyp is first decade in laryngeal papilloma is third and seventh decade in laryngeal tuberculosis is sixth and seventh decade in laryngeal cancer 4) The location of mass is between the anterior 1/3 and middle 1/3 of vocal cord in vocal nodule, polyp and papilloma middle 1/3 and posterior 1/3 in laryngeal tuberculosis and glottic (50%), supraglottic (42%), infraglottic (8%) in laryngeal cancer 5) The side of lesion is bilateral in vocal nodule and papilloma, the ratio of right to left is 2 : 3 in vocal polyp 6) The size is 1-2mm in vocal nodule and papilloma, 3-5mm in vocal polyp more than 10mm in laryngeal tuberculosis and laryngeal cancer 7) The duration of symptom is within 1 years in vocal nodule and vocal polyp and laryngeal papilloma, 1-several years in laryngeal tuberculosis and laryngeal cancer 8) The most frequent symptom was hoarseness 9) All laryngeal cancer was sguamous cell carcinoma

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Robust Friction Compensation Control Using a Nonliner Observer

  • Nakamura, Yuichiro;Niwa, Shohei
    • 제어로봇시스템학회:학술대회논문집
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    • 2001.10a
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    • pp.108.5-108
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    • 2001
  • The research of friction compensation control system seeks the accuracy, the velocity increase of the table, and the settling time reduction. The friction is the disturbance which has the greatest influence, but the past research of control system doesn´t perform exact modeling of the friction. So this research aims at the friction compensation control system, the exact modeling of the friction, comparison between the model simulation and experimental data, and the design of observer for the friction estimation.

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Some Common Fixed Point Theorems using Compatible Maps in Intuitionistic Fuzzy Metric Space

  • Park, Jong-Seo
    • International Journal of Fuzzy Logic and Intelligent Systems
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    • v.11 no.2
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    • pp.108-112
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    • 2011
  • Kaneko et a1.[4] etc many authors extended with multi-valued maps for the notion of compatible maps in complete metric space. Recently, O'Regan et a1.[5] presented fixed point and homotopy results for compatible single-valued maps on complete metric spaces. In this paper, we will establish some common fixed point theorems using compatible maps in intuitionistic fuzzy metric space.

Clinical Experience of Open Heart Surgery A Report of Annual 108 Cases (1984 년도 연간 개심술 108례 보고)

  • 박병순
    • Journal of Chest Surgery
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    • v.18 no.3
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    • pp.383-390
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    • 1985
  • 108 cases of open heart surgery were done at our department in 1984. There were 58 male and 50 female patients ranging in age from 20 months to 52 years. 75 cases were congenital heart disease, and 33 cases were acquired heart disease. There were 75 congenital heart anomalies with 5 operative deaths [6.7%], consisting of 62 acyanotic cases with 2 deaths [3.2%] and 13 cases of cyanotic cases with 3 deaths [23.1]. In 33 patients of acquired valvular disease, 29 valves were implanted; 20 mitral valve replacement with 2 death [10%], 2 aortic valve replacement with 1 death [50%], 2 double valve replacement [MVR+AVR] and 2 open mitral commissurotomy plus aortic valve replacement with no death. Postoperative, Warfarin sodium was medicated with checking prothrombin time. Finally, the operative mortality was 9.2% in congenital anomaly, and 9.1% in acquired heart disease, overall mortality rate was 9.3%.

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EFFECTS OF PHOSPHATIDYLETHANOL ON INOSITOL 1,4,5-TRIPHOSPHATE LEVEL OF CULTURED NG108-15 CELLS

  • Chung, In-Kyo;Kim, Chun-Do;Chung, Yong-Za;Kim, Inn-Se;Cho, Goon-Jae;Park, Chang-Hwa;Kim, Bong-Sun;Jang, Hye-Ock;Il Yun
    • Journal of Photoscience
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    • v.6 no.2
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    • pp.71-75
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    • 1999
  • Tempting to further understand the molecular mechanism of pharmacological action of ethanol, we evaluated effects of phosphatidylethanol (PET) on inositol 1,4,5-triphosphate (IP3) level and protein kinase C (PKC) activity in cultured NG108-15 cells. PET increased intracellular concentration of IP$_3$. PET incorporation into membranes of NG108-15 cells had no effect on the phosphorylation of the PKC-specific substrate MBP$\_$4-14/, thus indicates that PET does not affect PKC activity in this system.

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Comparison of particle size distribution and particle number concentration measured by APS 3321 and Dust Monitor 1.108 (APS 3321과 Dust Monitor 1.108을 이용한 입자 크기분포 및 수농도 측정결과 비교)

  • Lim, Kyoung-Soo;Park, Hyun-Seol
    • Particle and aerosol research
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    • v.5 no.2
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    • pp.63-70
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    • 2009
  • The size distribution and number concentration of atmospheric aerosol were measured and compared using APS 3321 and Dust Monitor 1.108. The particle size distribution and number concentration measured by two devices were also compared at a particle generation system of standard PSL and fly ash. The number concentration of atmospheric aerosol measured by APS was higher than that by Dust Monitor in particle size range of less than $3.0{\mu}m$, but there was good accordance between them in particle size range of over $3.0{\mu}m$. In the particle generation system of PSL and fly ash, different measurement results were shown because the particle concentration was higher than that of atmospheric aerosol. The number concentration measured by Dust Monitor was higher than that by APS in most particle size ranges. However, the peak concentration of PSL particles measured by Dust Monitor was lower than that by APS. The difference of the collection efficiency in a scrubber by APS and Dust Monitor measurement was less than 10%, but in the particle size of $1.5{\mu}m$, it was over 20%.

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