• 제목/요약/키워드: 4D Planning

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Plan Dose Evaluation of Three Dimensional Conformal Radiotherapy Planning (3D-CRT) of Nasopharyngeal Carcinoma (NPC): Experience of a Tertiary Care University Hospital in Pakistan

  • Abbasi, Ahmed Nadeem;Hafiz, Asim;Ali, Nasir;Khan, Khurshid Ahmed
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.10
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    • pp.5989-5993
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    • 2013
  • Background: Radiation therapy is the mainstay of treatment for nasopharyngeal carcinoma. Importance of tumor coverage and challenges posed by its unique and critical location are well evident. Therefore we aimed to evaluate our radiation treatment plan through dose volume histograms (DVHs) to find planning target volume (PTV) dose coverage and factors affecting it. Materials and Methods: This retrospective study covered 45 histologically proven nasopharyngeal cancer patients who were treated with definitive 3D-CRT and chemotherapy between Feb 2006 to March 2013 at the Department of Oncology, Section Radiation Oncology, Aga Khan University Hospital, Karachi, Pakistan. DVH was evaluated to find numbers of shrinking field (phases), PTV volume in different phases and its coverage by the 95% isodose lines, along with influencing factors. Results: There were 36 males (80%) and 9 females (20%) in the age range of 12-84 years. Stage IVA (46.7%) was the most common stage followed by stage III (31.1). Eighty six point six-percent received induction, 95.5% received concurrent and 22.2% received adjuvant chemotherapy. The prescribed median radiation dose was 70Gy to primary, 60Gy to clinically positive neck nodes and 50Gy to clinically negative neck regions. Mean dose to spinal cord was 44.2Gy and to optic chiasma was 52Gy. Thirty seven point eight-percent patients completed their treatment in three phases while 62.2% required four to five phases. Mean volume for PTV3 was $247.8cm^3$ (50-644.3), PTV4 $173.8cm^3$ (26.5-345.1) and PTV5 $119.6cm^3$ (18.9-246.1) and PTV volume coverage by 95% isodose lines were 74.4%, 85.7% and 100% respectively. Advanced T stage, intracranial extension and tumor volume > $200cm^3$ were found to be important factors associated with decreased PTV coverage by 95% isodose line. Conclusions: 3D CRT results in adequate PTV dose coverage by 95% isodose line. However advanced T stage, intracranial extension and large target volume require more advanced techniques like IMRT for appropriate PTV coverage.

Assessment of Dosimetric Leaf Gap According to Measuring Active Volume of Detector (검출기 측정 용적에 따른 Dosimetric Leaf Gap 변화와 정확성 검증에 대한 연구)

  • Dae-Hyun, Kim
    • Journal of the Korean Society of Radiology
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    • v.16 no.7
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    • pp.863-870
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    • 2022
  • DLG (Dosimetric Leaf Gap) and transmission factor are important parameters of MLC modeling in treatment planning system. In this study, DLG and transmission factor of HD-MLC were measured using detector with different measuring volumes, and the accuracy of the treatment plans was evaluated according to the DLG values. DLG was measured using the dynamic sweeping gap method with Semiflux3D and MicroDiamond detectors. Then, 10 radiation treatment plans were generated to optimize the DLG value and compared with the measurement results. Photon energies 6, 8, 10 MV, the DLG measured by Semiflux3D were 0.76, 0.83, and 0.85 mm, and DLG measured by MicroDiamond were 0.78, 0.86, and 0.9 mm. All plans were measured by portal dosimetry and analyzed using Gamma Evaluation. In the 6 MV photon beams, the average gamma passing rate were 94.3% and 98.4% for DLG 0.78 mm and 1.15 mm. In the 10 MV photon beam, the average gamma passing rate were 91.2% and 97.6% for DLG 0.9 mm and 1.25 mm. HD-MLC needs accurate modeling in the treatment planning system. DLG could be used measured data using small volume detector. However, for better radiation therapy, DLG should be optimized at the commissioning stage of LINAC.

Effents of Plant Explant Position of Miscanthus and Medium Supplements on Callus Induction (억새(Miscanthus spp.) 식물재료와 배지 첨가물질이 캘러스 형성에 미치는 영향)

  • Kim, Kwang-Soo;Kwon, Da-Eun;Lee, Ji-Eun;Cha, Young-Lok;Moon, Youn-Ho;Song, Yeon-Sang;Kang, Yong-Ku
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2018.04a
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    • pp.54-54
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    • 2018
  • 억새(Miscanthus spp.)는 우리나라 등 동아시아가 원산이며 바이오매스량이 많아 바이오에너지 원료작물로서 잠재성이 크기 때문에 2세대 바이오에탄올 생산 원료로 주목을 받고 있고, 축산깔개 및 토양개량제 등으로도 이용되고 있다. 미국과 유럽 등에서는 생태계 교란 방지를 위해 4배체 물억새(M. sacchariflorus)와 2배체 참억새(M. sinensis)의 종간 교잡 이질 3배체인 불임성 억새(M. x giganteous)을 주로 재배하고 있으나, 단일 유전형의 품종으로 병해충과 자연재해에 취약하여 다양한 억새 품종의 개발이 시급한 실정이다. 본 연구는 억새를 재료로 하여 반수체 및 배수체 확보를 통한 배수성 별 특성 평가와 함께 기내배양을 통해 탈분화 및 재분화 시스템을 구축하여 억새의 육종 효율을 높이기 위해서 실시하였다. 억새 종자로부터 캘러스의 유도는 MS배지와 N6배지에 1mg/L 2.4-D를 첨가하였을 때 비배발생 캘러스(nonembryogenic callus)가 유도되었고, N6배지에 3~5 mg/L 2,4-D를 첨가하였을 때 배발생 캘러스(embryogenic callus)가 발생하였다. MS배지보다는 N6배지에서 캘러스 유도율이 높았으며, 식물생장조절제로 2,4-D와 BA 조합처리 보다 2,4-D 단용 처리하였을 때 캘러스 유도율이 더 높았다. 억새 종에 따른 캘러스 유도율은 물억새가 25.2~49.3%, 참억새는 30.3~52.0%였고 거대억새는 62.6~81.1%로 나타났다. 억새 신초 및 줄기로부터의 캘러스 유도율은 물억새가 4.4~17.2%, 참억새는 1.8~7.7%, 거대억새는 15.3~19.9%로 나타나 종자에 비해 매우 낮았다. 미성숙화기로부터의 캘러스 유도는 억새 종에 따른 차이가 없었으며, 3mg/L 2,4-D 첨가 배지에서 캘러스 유도율이 비교적 낮았고(60~80%), 1mg/L와 5mg/L의 2,4-D가 첨가된 배지에서 캘러스 유도율이 높게(90~95%) 나타났다.

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The Analysis of the Possibility for Using Converged Spatial Information(CSI) in National Territorial Planning - The Case Study of LH's Future Business about Land and Housing (융복합 공간정보의 국토계획 분야 활용가능성 분석 - LH 국토·주택관련 미래사업 예시를 중심으로)

  • Choi, Jun Young
    • Spatial Information Research
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    • v.21 no.4
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    • pp.71-81
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    • 2013
  • Due to explosively increasing utilization in spatial information and a rapid development in geospatial technology related to national territorial and housing, there are increasing demands for converging spatial information on not only urban planning and real estate data but also newly generated data from smart phone, GPS to achieve comparative advantage of national territory. In this paper, we prospect the utilization of Converged Spatial Information(CSI) to future national territorial planning for the purpose of enhancing territorial competitiveness. For this purpose, considering the Korea Land and Housing corporation(LH) takes charge most of government's land and housing development projects, CSI usage of this company's 6 future business domains until 2029 were used as a case study. Also, 7 CSIs derived from literature review were surveyed to find the degree of CSI utilization in the national territorial future. In the analysis result, it was found that 3D data and mobile data among others have higher degree of utilization, and urban and regional development is the most highly utilizable domain for CSIs. After all, to revitalize the use of CSI in national territorial future, it is required to do a balanced construction of territorial use spatial information about marine use, coastal use, underground space besides land use.

An Empirical Study on Predictive Modeling to enhance the Product-Technical Roadmap (제품-기술로드맵 개발을 강화하기 위한 예측모델링에 관한 실증 연구)

  • Park, Kigon;Kim, YoungJun
    • Journal of Technology Innovation
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    • v.29 no.4
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    • pp.1-30
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    • 2021
  • Due to the recent development of system semiconductors, technical innovation for the electric devices of the automobile industry is rapidly progressing. In particular, the electric device of automobiles is accelerating technology development competition among automobile parts makers, and the development cycle is also changing rapidly. Due to these changes, the importance of strategic planning for R&D is further strengthened. Due to the paradigm shift in the automobile industry, the Product-Technical Roadmap (P/TRM), one of the R&D strategies, analyzes technology forecasting, technology level evaluation, and technology acquisition method (Make/Collaborate/Buy) at the planning stage. The product-technical roadmap is a tool that identifies customer needs of products and technologies, selects technologies and sets development directions. However, most companies are developing the product-technical roadmap through a qualitative method that mainly relies on the technical papers, patent analysis, and expert Delphi method. In this study, empirical research was conducted through simulations that can supplement and strengthen the product-technical roadmap centered on the automobile industry by fusing Gartner's hype cycle, cumulative moving average-based data preprocessing, and deep learning (LSTM) time series analysis techniques. The empirical study presented in this paper can be used not only in the automobile industry but also in other manufacturing fields in general. In addition, from the corporate point of view, it is considered that it will become a foundation for moving forward as a leading company by providing products to the market in a timely manner through a more accurate product-technical roadmap, breaking away from the roadmap preparation method that has relied on qualitative methods.

A Survey on Health Service Activities of Public Health Nurses in Inchon & Kyung Gi Area (인천.경기지역 보건소 간호사의 보건사업 수행에 관한 조사 연구)

  • Kim, Myeong-Sun
    • Research in Community and Public Health Nursing
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    • v.1 no.1
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    • pp.88-102
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    • 1989
  • This survey was conducted in order to find out the degree of health service activities of Public Health Nurses & variables relevant to their activities. The subjects of this survey were 232 PHN in Health Centers, Inchon & Kyung Gi area. Data were collected by mean of questionairs from 30th, September to 30th, October, 1986. For the analysis, ANOVA was used. The results were as follows; 1. General characteristics of PHN: o An approximately four fifth of the subjects (82.3%) was between 20-39 years. o The average career length of the subjects as PHN was 4 years. o Their educational level was almost Nursing School (22.4%) Junior College of Nursing (53.4%). o The marital status of the subjects was already married (75.4%). 3. The degree of health service activities of PHN; o The total mean of health service activities was 2.147 (S.D: 1.477, range 11-5). o Among the 11 Health Service Categories; Health service planning (2.828) is the highest mean scored category. The lowest mean scored category was the other health services. o Among the specific activity items about the 11 health service categories, the highest scored activities were 'personal counselling & education' in well-baby care (2.504), family planning (2.530), Tb control (2.134), disease control (2.371), 'health history taking & health examination', in prenatal care, 'clinic care', in administrative service, 'record & report', in the other categories. o Almost categories (10), 'Home visiting' was the lowest scored activity. 3. The relevance for the health service activities by several variables were as follows; o The relevance for the health service activities by general characteristics of PHN was not shown significance at age, educational level, marital status, relegion status. o And at work place, & work department was shown high significance.

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Dosimetric Evaluation of 3-D Conformal and Intensity-modulated Radiotherapy for Breast Cancer after Conservative Surgery

  • Mansouri, Safae;Naim, Asmaa;Glaria, Luis;Marsiglia, Hugo
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.11
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    • pp.4727-4732
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    • 2014
  • Background: Breast cancers are becoming more frequently diagnosed at early stages with improved long term outcomes. Late normal tissue complications induced by radiotherapy must be avoided with new breast radiotherapy techniques being developed. The aim of the study was to compare dosimetric parameters of planning target volume (PTV) and organs at risk between conformal (CRT) and intensity-modulated radiation therapy (IMRT) after breast-conserving surgery. Materials and Methods: A total of 20 patients with early stage left breast cancer received adjuvant radiotherapy after conservative surgery, 10 by 3D-CRT and 10 by IMRT, with a dose of 50 Gy in 25 sessions. Plans were compared according to dose-volume histogram analyses in terms of PTV homogeneity and conformity indices as well as organs at risk dose and volume parameters. Results: The HI and CI of PTV showed no difference between 3D-CRT and IMRT, V95 gave 9.8% coverage for 3D-CRT versus 99% for IMRT, V107 volumes were recorded 11% and 1.3%, respectively. Tangential beam IMRT increased volume of ipsilateral lung V5 average of 90%, ipsilateral V20 lung volume was 13%, 19% with IMRT and 3D-CRT respectively. Patients treated with IMRT, heart volume encompassed by 60% isodose (30 Gy) reduced by average 42% (4% versus 7% with 3D-CRT), mean heart dose by average 35% (495cGy versus 1400 cGy with 3D-CRT). In IMRT minimal heart dose average is 356 cGy versus 90cGy in 3D-CRT. Conclusions: IMRT reduces irradiated volumes of heart and ipsilateral lung in high-dose areas but increases irradiated volumes in low-dose areas in breast cancer patients treated on the left side.

A Derivation of Comprehensive Protection Ratio and Its Applications for Microwave Relay System Networks

  • Suh Kyoung-Whoan
    • Journal of electromagnetic engineering and science
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    • v.6 no.2
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    • pp.103-109
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    • 2006
  • This paper suggests an efficient and comprehensive algorithm of the protection ratio derivation and illustrates some calculated results applicable to the initial planning of frequency coordination in the fixed wireless access networks. The net filter discrimination associated with Tx spectrum mask and overall Rx filter characteristic has been also examined to show the effect of the adjacent channel interference. The calculations for co-channel and adjacent channel protection ratios are performed for the current microwave frequency band of 6.7 GHz including Tx spectrum mask and Rx filter response. According to results, fade margin and co-channel protection ratio reveal 41.4 and 75.2 dB, respectively, for 64-QAM and 60 km at BER $10^{-6}$. It is shown that the net filter discrimination with 40 MHz channel bandwidth provides 28.9 dB at the first adjacent channel, which yields 46.3 dB of adjacent channel protection ratio. In addition, the protection ratio of 38 GHz radio relay system is also reviewed for millimeter wave band applications. The proposed method gives some advantages of an easy and systematic extension for protection ratio calculation and is also applied to frequency coordination in fixed millimeter wave networks.

Development of the Theoretical Model on Electronic-Store Success (전자상점 성과에 관한 이론적 모형 구축)

  • 윤철호;김상훈
    • Korean Management Science Review
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    • v.20 no.2
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    • pp.113-133
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    • 2003
  • This study developed the ISM (Electronic Store Success Model) by basing upon the revised D&M IS Success Model and reflecting the characteristics of marketing and e business. The theoretical rationale of this model was as following : 1) Though the revised D&M IS Success Model (2002) must be more logical and complete model than the original D&M IS Success Model (1992), it did not reflect characteristics of marketing and e business. 2) In the marketing studios, Service Quality has been suggested as one of basic strategies for success. 3) In e business studies, Trust has been emerging as a potentially important antecedent of e loyalty. 4) There has been a paradigm shift from satisfaction to loyalty in marketing emphasis. 5) Nowadays, ERP (Enterprise Resource Planning) has been pervaded in many organizations and has supported PCA (Profit Center Accounting) or Channel based Accounting, so it has not been difficult to evaluate financial performance of Electronic Store. The ESM that has six dimensions (System Quality, information Quality. Service Quality, Trust, Loyalty, Financial Performance) and expresses the causal relationship among them was proposed and was compared with BSC (Balanced Scorecard), WebQual, and EWAM (Extended Web Assessment Method). The results showed that the ESM coincides with BSC and contains dimensions of WebQual, and EWAM.

The Image and Preference Comparison between 'Opened Landscape' and 'Filtered Landscape' - Focused on With and Without Parallax Effect - ('열린경관'과 '가려진경관'의 이미지와 선호도 비교 - 패럴랙스(Parallax) 효과 유무를 중심으로 -)

  • Rho, Jae-Hyun
    • Journal of the Korean Institute of Landscape Architecture
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    • v.35 no.4
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    • pp.105-118
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    • 2007
  • The purpose of this study is not only to compare between 'Opened Landscape' and 'Filtered Landscape' image and preference but also to suggests a guide line of planting design for progressive realization. For this, the image structures of photo-sketch simulation for parallax landscape have been investigated by Semantic Differential scale(S.D. scale) and the Factor analysis. The results could be summarized as follows. The results of S.D. scale values for landscape through parallax were greater than non-parallax landscape. The scenes through parallax were better preferred to direct view. Thus the results of photo-sketch simulation test support the expected hypothesis that the visual environment of complexity and variety is closely correlated with the parallax effect and monotonous or non-parallax environment, and parallax effect on close view more bigger than the distant view. Factors covering the spatial image of parallax landscape were found to be seven and Total values were 60.35 %. The most important factors determining the parallax effect were Factors I 'depth of space' and VI 'expectation of space and interest'. An outstanding view must be handled properly to be preserved or accentuated. In this sense, the parallax spatial beauty with tree could be improved through the visual aspects of plan arrangements and the progressive realization appeared to be one effective design technique for landscape planning and design.