• Archives of Reconstructive Microsurgery
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• v.4 no.1
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• pp.52-57
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• 1995

The authors have reviewed 19 patients of brachial plexus injury who treated by operative methods at Department of Orthopedic Surgery, Korea University Hospital during the period from January 1989 to February 1994. All of these patients were followed up more than one year and following results were obtained. 1. The whole arm type injury was most common(7 of 19 patient) and supraclavicular lesion(15 of 19 patient) was more dominant than infraclavicular lesion(4 of 19 patients). 2. The neurorrhaphy, nurolysis, nerve grafting, and neurotization were performed for the primary neural surgery and secondary reconstructive procedure consist of musculotendinous transfer and free muscle transfer with neurotization. 3. The followed up period was from one year to four years and six months, average being two years and five months. 4. We have obtained satisfactory results in 12 patients among 19 patients.

• IMMUNE NETWORK
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• v.21 no.1
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• pp.4.1-4.18
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• 2021

The global outbreak of coronavirus disease 2019 (COVID-19) is still threatening human health, economy, and social life worldwide. As a counteraction for this devastating disease, a number of vaccines are being developed with unprecedented speed combined with new technologies. As COVID-19 vaccines are being developed in the absence of a licensed human coronavirus vaccine, there remain further questions regarding the long-term efficacy and safety of the vaccines, as well as immunological mechanisms in depth. This review article discusses the current status of COVID-19 vaccine development, mainly focusing on antigen design, clinical trials in later stages, and immunological considerations for further study.

• Journal of Preventive Medicine and Public Health
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• v.55 no.4
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• pp.321-333
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• 2022

Objectives: Extensive evidence links low vitamin D status and comorbidities with coronavirus disease 2019 (COVID-19) outcomes, but the results of published studies are contradictory. Therefore, we investigated the association of lower levels of vitamin D and comorbidities with the risk of COVID-19 infection. Methods: We searched MEDLINE (via PubMed), Cochrane Central Register of Controlled Trials, and ClinicalTrials.gov for articles published until August 20, 2021. Sixteen eligible studies were identified (386 631 patients, of whom 181 114 were male). We included observational cohort and case-control studies that evaluated serum levels of vitamin D in COVID-19-positive and COVID-19-negative patients. Mean differences (MDs) with 95% confidence intervals (CIs) were calculated. Results: Significantly lower vitamin D levels were found in COVID-19-positive patients (MD, -1.70; 95% CI, -2.74 to -0.66; p=0.001), but with variation by study design (case-control: -4.04; 95% CI, -5.98 to -2.10; p<0.001; cohort: -0.39; 95% CI, -1.62 to 0.84; p=0.538). This relationship was more prominent in female patients (MD, -2.18; 95% CI, -4.08 to -0.28; p=0.024) than in male patients (MD, -1.74; 95% CI, -3.79 to 0.31; p=0.096). Male patients showed higher odds of having low vitamin D levels (odds ratio [OR], 2.09; 95% CI, 1.38 to 3.17; p<0.001) than female patients (OR, 1.17; 95% CI, 0.74 to 1.86; p=0.477). Comorbidities showed inconsistent, but generally nonsignificant, associations with COVID-19 infection. Conclusions: Low serum vitamin-D levels were significantly associated with the risk of COVID-19 infection. This relationship was stronger in female than in male COVID-19 patients. Limited evidence was found for the relationships between comorbidities and COVID-19 infection, warranting large population-based studies to clarify these associations.

• International Journal of Computer Science & Network Security
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• v.22 no.4
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• pp.159-168
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• 2022

The recent outbreak of COVID-19 pandemic cases around the globe has affected Saudi Arabia with around 15, 00,000 confirmed cases within the initial 4 months of transmission. The present investigation analyzed the relationship between daily COVID-19 confirmed cases and meteorological parameters in seventeen cities of KSA. We used secondary published data from the Ministry of Health, KSA daily dataset of COVID-19 confirmed case counts. The meteorological parameters used in the present investigation are temperature, humidity, dew point, and wind speed. Pearson correlation and Spearman rank correlation tests were utilized for data analysis. The incubation period of COVID-19 varies from 1 day to 14 days as per available information. Therefore, an attempt has been made to analyze the effects of meteorological factors with bins of 1, 3, 7, and 14 days. The results suggested that the highest number of correlations (15 cities) was observed for temperature (maximum, minimum, and average) and humidity (12 cities) (minimum and average). The dew point showed relationships for 7 cities and wind showed moderate correlations only for 2 cities. The study results might be useful for authorities and stakeholders in taking specific measures to combat the Covid-19 pandemic.

• International journal of advanced smart convergence
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• v.11 no.4
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• pp.260-265
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• 2022

This study aimed to determine whether lactate dehydrogenase (LDH) levels in coronavirus disease (COVID-19) patients in Korea were higher than those in patients without COVID-19, and the effect of sex and age on LDH levels. A retrospective, observational study was conducted to measure LDH levels in 247 and 225 female and male COVID-19 patients, respectively, who were admitted to the study hospital between April 1 and October 30, 2020. Serum LDH levels were measured using an automated analyzer. Results: LDH levels were elevated in both male and female patients with COVID-19. Among patients with COVID-19, LDH levels were higher in males than in females, and LDH levels were higher in patients with COVID-19 than in patients in the control group. In the analysis of differences in LDH levels by age, LDH levels in patients with COVID-19 increased statistically significantly with age in males and females (males: p=0.001, females: p=0.001). By examining the differences in LDH levels according to sex and age, this study contributed to the basic biochemical data available in Korea, particularly regarding patients with COVID-19. Further research may be needed to examine confounding variables.

• Journal of Digital Convergence
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• v.20 no.4
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• pp.469-482
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• 2022

The purpose of this study is to analyze regional variation factors of hypertension treatment rate in COVID-19 based on the analysis results based on ecological methodology. To this end, data suitable for ecological analysis were collected from the Korea Centers for Disease Control and Prevention's regional health statistics, local government COVID-19 confirmed cases, National Health Insurance Corporation, Health Insurance Review and Assessment Service's welfare statistics, and Korea Transport Institute's traffic access index. Descriptive statistics and correlation analysis were conducted using SPSS Statistics 23 for regional variation and related factors in hypertension treatment rate, and geographical weighted regression analysis was conducted using Arc GIS for regional variation factors. As a result of the study, the overall explanatory power of the calculated geo-weighted regression model was 27.6%, distributed from 23.1% to 33.4% by region. As factors affecting the treatment rate of hypertension, the higher the rate of basic living security medical benefits, diabetes treatment rate, and health institutions per 100,000 population, the higher the rate of hypertension treatment, the lower the number of COVID-19 confirmed patients, the lower the rate of physical activity, and the alcohol consumption. Percentage of alcohol consumption decreased due to COVID-19 pandemic. It was analyzed that the lower the ratio, the higher the treatment rate for hypertension. Based on these results, the analysis of regional variables in the treatment rate of hypertension in COVID-19 can be expected to be effective in managing the treatment rate of hypertension, and furthermore, it is expected to be used to establish community-centered health promotion policies.

• Korean Journal of Culture and Social Issue
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• v.27 no.4
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• pp.629-659
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• 2021

This study compared the influences of Korean psycho-social experiences on emotional-distress(stress, depression, anxiety, anger) of Koreans between two-periods during COVID-19. First, an online survey was conducted among 600 participants between April 13, 2020 and 21, while WHO had declared the pandemic, and Daegu-Gyungbuk were declared as a special-disaster area. Second, an online survey was conducted among 482 participants out of 600 study participants from the first study during August 21 to September 2, while COVID-19 re-spreaded around the world, and total confirmed cases were over 1,000 for a week in Seoul-Gyeonggi province. Hierarchical-regression analysis was used to determine the influence of personal characteristics, fear and social constraints, relationship conflict and income-decreasing factors on stress, depression, anxiety, anger in the two-time points. Results suggest that gender, quality-of-life, 'frequent information-checking about COVID-19', 'fear of unpredictability' and 'difficulties on hospital treatment access' predicted distress(stress, depression, anxiety, anger) at both Time1 and 2. 'Difficulties with official schedule' predicted distress at Time 1, and age, vulnerability to infection and difficulties with personal schedules predicted distress(stress, depression, anxiety, anger) at Time 2. Based on the reseults, implications and recommendations were presented.

• Korean journal of applied entomology
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• v.19 no.1 s.42
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• pp.45-50
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• 1980

The control effects of four systemic insecticides $Disyston^{(R)}$ (disulfoton) 5G, $Temik^{(R)}$ (aldicarb) 15G, $Ortran^{(R)}$ (acephate) 5G and $Curaterr^{(R)}$ (carbofuran) 3G, on small brown planthopper, Laodetphax striatellus (fallen), were studied by applying them in the furrow of spring barley field. Two different application times; April 19 and 25, and three different dosage rates were used. The results are as follows: 1. No significant difference in the mortalities among the developmental stages were observed with the treated barley on April 25, when various life stages had infested on the cutting of the treated barley in the laboratory. The residual periods were 19 days for Disyston and 31 days for Temik. 2. With field experiments, highly effective control effects were obtained with Disyston and Temik. The residual period was longer with the treatment on April 19 than with those on April 25 for Disyston, while they were reverse for Temik. 3. The effective doses were 2kg/10a for Disyston, while the effectiveness lasted more than 40days with dose of 1kg/10a for Temik. 4. From above results, Disyston and Temik could effectively reduce the population of small brown planthopper in the barley field, which is the effective reproductive sources of the population in the rice field.

• Korean Journal of Mathematics
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• v.27 no.3
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• pp.767-777
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• 2019

We present a new way of obtaining the complete factorization of $X^n-1$ for n = 15, 17, 19 over the 4-adic ring ${\mathcal{O}}_4[X]$ of integers and thus over the Galois rings $GR(2^e,2)$. As a result, we determine all cyclic codes of lengths 15, 17 and 19 over those rings. This extends our previous work on such cyclic codes of odd lengths less than 15.

• Pediatric Infection and Vaccine
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• v.29 no.3
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• pp.131-140
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• 2022

Purpose: Since the coronavirus disease 2019 (COVID-19) pandemic began, new variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have emerged, and distinct epidemic waves of COVID-19 have occurred for an extended period. This study aimed to analyze the clinical and epidemiological characteristics of children with COVID-19 from the third wave to the middle of the fourth epidemic wave in Korea. Methods: We retrospectively reviewed the medical records of hospitalized patients aged ≤18 years with laboratory-confirmed COVID-19. The study periods were divided into the third wave (from November 13, 2020 to July 6, 2021) and the fourth wave (from July 7 to October 31, 2021). Results: Ninety-three patients were included in the analysis (33 in the third and 60 in the fourth waves). Compared with the third wave, the median age of patients was significantly older during the fourth wave (6.7 vs. 2.8 years, P=0.014). Household contacts was reported in 60.2% of total patients, similar in both periods (69.7 vs. 55.0%, P=0.190). Eighty-one (87.1%) had symptomatic SARS-CoV-2 infection. Among these, 10 (12.3%) had no respiratory symptoms. Anosmia or ageusia were more commonly observed in the fourth epidemic wave (10.7 vs. 34.0%, P=0.032). Most respiratory illness were upper respiratory tract infections (94.4%, 67/71), 4 had pneumonia. The median cycle threshold values (detection threshold, 40) for RNA-dependent RNA polymerase (RdRp) and envelope (E) genes of SARS-CoV-2 were 21.3 and 19.3, respectively. There was no significant difference in viral load during 2 epidemic waves. Conclusions: There were different characteristics during the two epidemic waves of COVID-19.