• Title/Summary/Keyword: 4-DAMP

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Clinical Study of Atopic Dermatitis ; the Classification of Oriental Medical Clinical type and Treatment (아토피 피부염 환자에 대한 임상적 연구; 한의학적인 임상유형분류 및 치료)

  • 윤화정;고우신
    • The Journal of Korean Medicine
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    • v.22 no.2
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    • pp.10-21
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    • 2001
  • Objectives : Atopic dermatitis(AD) assume an remarkable clinical aspect and it s diagnosis almost depends on clinical symptoms. Therefore, we aimed to study the clinical diagnostic standard of AD for more accurate treatment. We repert as follows; Methods : For 6 months from March to August in 2000 we selected fifty outpatients who were prognosis of AD in the department of dermatology, Oriental medical hospitol, Dong-eui University. Results and Conclusions : 1. We classified of the grade, the condition of AD patient was slight and severe, by the sum of total by the clinical index of AD (diagnostic features). 2. By consulting previous oriental medical theories, we divided symptom-complex of AD into two type ; one was damp-heat type and the other was deficiency of blood- wind-dryness type. 3. Male to female ratio was 17 : 33 and the third stage, more than half of the patients were adolescents. 4. According to the results of symptom-complex of AD patients, on the first examination damp-heat type was more than deficiency of blood-wind-dryness type and in progressing treatment, the condition has been change to deficiency of blood-wind-dryness type. 5. In the lesions of AD, arm and knee were most serious skin lesions and in symptoms of AD, pruritus was most complained, and in progressing treatment, erosion and erythema were greatly improved. 6. When we measured the levels of serum Total IgE, that of thirty eight patientswere higher than that of normal, but elevation of serum IgE levels was not correlated with the severity of AD.

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A Literatural study of the acupuncture on Dudurugi(두드러기) (두드러기의 원인 증상 및 침구치료에 관한 문헌적 연구)

  • Hwang Bae-Youn;Hong Seung-Won;Lee Sang-Ryong
    • Korean Journal of Acupuncture
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    • v.20 no.2
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    • pp.101-120
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    • 2003
  • This study is performed to investigate the cause, symptom and acupuncture on Dudurugi through the literature of oriental medicine. The findings of this study are as follows: 1. Dudurugi is caused by exogenous pathogenic factors(wind, heat, cold, damp), sthenic inter damage factors(heat accumulated in the intestine and stomach, blood-heat, blood-stasia) and asthenia inter damage factors(asthenia of the spleen and stomach, blood-asthenia, asthenia of energy-blood, yin-asthenia and blood-dryness, yan-asthenia and energy-asthenia). 2. The symptom of Dudurugi is appeared in the skin and its surface is processed apparently or itch. 3. The treatment of Dudurugi was used by expelling the wind with removing pathogen. 4. In the treatment of Dudurugi, The su-yangmyong taejang-kyong of 12 merdians was mainly used and, the kokchi(LI11) of acupoints was most used in the acupuncture and moxibustion. 5. In the treatment of Dudurugi, acupoints of tok-maek and chok-t'aeyangkyong were mainly used in the case of showing symptoms caused by exogenous pathogenic factors and, acupoints of chok-t'aemkyong were mainly used in the case of showing symptoms caused by damp-heat accumulated in the intestine and stomach. When there were any other symptoms accompanied, other acupoints were more used.

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The literature study on Contact dermatitis (接觸性 皮膚炎에 關한 文獻的 考察)

  • Jeon, Jae-Hong;Kim, Hyun-A;Kang, Yun-Ho
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.10 no.1
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    • pp.263-283
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    • 1997
  • The study has been carried out to investigate of the Contact dermatitis by referring to 37 literature. The results were as follows; 1. In oriental medical science, Contact dermatitis is belong to the cartegory of the 'Chilchang(漆瘡)', 'Honyoja(狐尿刺)', 'Bunhwachang(粉花瘡)', 'Goyakpoong(膏藥風)', 'Matongsun(馬桶癬)'. 2. The cause of a disease is combination of internal factor-the weak of skin or the constitutional factor and external factor-the toxic substance. When the toxic substance contacts skin, pathologial change-stagnation of vital energy and blood(氣血鬱滯)-appears, and after the stagnation of vital energy and blood change heat(化火熱). 3. The symptom of a disease is topical itching, burning pain, erythematous papule, vesicle etc in skin in the acute state and itching, pachyderma, lichenification etc in skin in the chronic state. The symptom is differentiated to wind-heat(風熱) syndrom, damp-heat(濕熱) syndrom, toxic heat(熱毒) syndrom in the acute state and blood dryness(血燥) sydrom in the chronic state. 4. The treatment-methodes is as follow ; Until chung dynasty(淸代) the greater part of treatment is externl treatment The present age in china use together internal treatment and external treatment, in the acute state use method of remove heat(淸熱), remove wind(祛風), remove damp(利濕), detoxicating(解毒), remove heat from blood(凉血), in the chronic state use method of remove wind(祛風) and nourishing the blood(養血).

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A Study on Application of Hwangnyeonhaedok-tang Blended Prescriptions in Dongeuibogam (동의보감(東醫寶鑑) 중(中) 황연해독탕(黃連解毒湯)의 활용(活用)에 대한 연구(硏究))

  • Kim, Hyeong-Yul;Lee, Sang-Hyun;Yun, Young-Gab
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.22 no.1
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    • pp.195-218
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    • 2009
  • The results of documentary survey of 81 prescriptions of Hwangnyeonhaedok-tang and Hwangnyeonhaedok-tang blended ones introduced in Dongeuibogam in which there are 42 of prescriptions using Hwangnyeonhaedok-tang as main constituent and 39 of prescriptions using Hwangnyeonhaedok-tang as assistant constituent can be summarized as followings, 1. Hwangnyeonhaedok-tang blended prescriptions using Hwangnyeonhaedok-tang as main constituent are applied to 20 categories of disease such as 7 of external disease from the chapters of various dermatos is, various injury, tumor(16.6%), 5 of fire disease from the chapter of fire(12%), 5 of eye diseases from the chapter of eye(12%), 4 of disease originated from damage by coldness from the chapter of coldness(9%), etc. 2, It has been found that mainly considered causative agents in diseases, when making up Hwangnyeonhaedok-tang blended prescriptions using Hwangnyeonhaedok-tang as main constituent, are feverish toxin in internal organs, followed by exogenous damp and fever, feverish toxin from damage by coldness and more such as extravasated blood, damp toxin, lack of ki and blood, lack of yin, congestion, the seven passions, blood overflow and excess liquor and sex.

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Corrosion mitigation of photovoltaic ribbon using a sacrificial anode (희생양극을 이용한 태양광 리본의 부식 저감)

  • Oh, Wonwook;Chan, Sung-Il
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.3
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    • pp.681-686
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    • 2017
  • Degradation is commonly observed in field-aged PV modules due to corrosion of the photovoltaic ribbon. The reduced performance is caused by a loss of fill factor due to the high series resistance in the PV ribbon. This study aimed to mitigate the degradation by corrosion using five sacrificial anodes - Al, Zn and their alloys - to identify the most effective material to mitigate the corrosion of the PV ribbon. The corrosion behavior of the five sacrificial anode materials were examined by open circuit potential measurements, potentiodynamic polarization tests, and galvanic current density and potential measurements using a zero resistance ammeter. Immersion tests for 120 hours were also conducted using materials and damp heat test tests were performed for 1500 hours using 4 cell mini modules. The Al-3Mg and Al-3Zn-1Mg sacrificial anodes had a low corrosion rate and reduced drop in power, making then suitable for long-term use.

A study of literature on acupuncture & moxibustion techniques to treat 10 kinds of lumbago described by Huh Jun in DongUiBoGam(東醫寶鑑) (동의보감(東醫寶鑑) 요통분류(腰痛分類)에 따른 십종요통(十種腰痛)의 침구치료(針灸治療)에 대(對)한 문헌연구(文獻硏究))

  • Shin, Jong-Keun;Kim, Kyung-Sik;Sohn, In-Chul
    • Korean Journal of Acupuncture
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    • v.21 no.3
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    • pp.175-202
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    • 2004
  • The Object of this study is as follows. we classify lumbago into ten kinds as mentioned in DongUiBoGam(東醫寶鑑), and are going to present each acupunture & moxibustion treatment. For the purpose of looking for each treatment, we referred to a large number of literature for lumbago treatment from ancient to modern. As a result of survey the references, we found out that lumbago due to kidney deficiency(腎虛腰痛) and lumbago due to cold-damp(寒濕腰痛) are more mentioned in many references than any other kinds, and that ten kinds of lumbago have each treatment. above all, In treatment of lumbago due to kidney deficiency(腎虛腰痛) bladder meridian, governor vessel meridian, kidney meridian and general points such as BL23, KI3, BL40, GV4, BL52 are used much in turn. also in treatment of lumbago due to cold-damp(寒濕腰痛) bladder meridian, governor vessel meridian, gallbladder meridian and general points such as BL23, BL40, GV3, GV4, SP9, GB30, Ah-Shi' points(阿是穴), BL25 are used much in turn. We conclude that ten kinds of lumbago have each different acupunture & moxibustion points and treatments, so if we follow each treatment we might obtain more higher rate of the treatment of lumbago.

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Study for Relationship between the Type of Differentiation of Symptoms and Signs of Oriental Gynecology and Sasang Constitution (In the Field of the Patiehts who chiefly complained Feeling of Cold) (부인과(婦人科) 냉증환자(冷症患者)의 변증유형(辨證類型)과 사상체질(四象體質)과의 관계에 대한 소고(小考))

  • Lee, In-seon;Kim, Jong-weon;Lee, Sang-hoon
    • Journal of Sasang Constitutional Medicine
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    • v.9 no.2
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    • pp.263-281
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    • 1997
  • We studied the relationship between each type which was figured out by the question paper given to the patients who chiefly complained feeling of cold and Sasang constitution. The results are as follows. 1. Diagnoses in woman's disease with feeling of cold(冷病) are abdomnal mass(uterine myoma, ovarian cyst), dysmenorrhea, leukorrhea and infertility, orderly in number. They have commoness in the origin of disease which are stagnation of Qi(氣滯) and blood stasis(血瘀), cold(寒), damp(濕) and we can find the causes of feeling of cold are stagnation of blood(血瘀) and harmness of damp(水毒). 2. In the type of survey through the question paper, the largest number of the origin of that disease is cold, the next is blood stasis and dificiency of Qi(氣虛), dificiency of blood(血虛), stagnation of Qi, damp phlegm(濕痰) etc. 3. (1)The numbers by constitutional assortment of object are like this. Taeumin are 23 persons,Soumin 14 and Soyangin 6, so we can find the feeling of cold turn up evenly in all constitution but the number of Soyangin was relatively small. (2)The inclination of constitutional type is the highest in Soumin and they often have and feel strongly disorders of their body. (3)We could find the corelation of theoretical background of Sasang Medicine in constitutional type of survey. 4. (1)The numbers by constitutional assortment of the patients with feeling of cold and numbness(冷痺症) are like this. Taeumin are 16 persons, Soumin 7 and Soyangin 3, as are like the distribution of 3-(1). (2)The inclination of constitutional type is the highest Soumin, so they have multiple type of differentiation of symptoms and signs and their symptoms is old and severe, therefore they need long time for cure. In all, except the symptom with feeling of cold caused by dificiency of the blood and insufficiency of yang(氣虛와 陽虛) that we meet frequently on clinic is numerous, the number of that caused by stagnation of Qi and blood(氣滯와 血滯) alike dysautonomia is also large. And we can find the feeling of cold turn up evenly in all constitution but the number of Soyangin was relatively small. Within the case of Soumin, they have both dificiency of Qi and blood, have complex source, so their symptoms are old and severe and they need long time for cure. In Taeumin, they are of large number with dificiency of Qi and we think thst that are concerned with the symptom of exterior cold.

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Reliability Study of Diagnos System of Oriental Medicine (r) S.1.1 (한방진단설문지 DSOM (r) S.1.1의 신뢰도연구)

  • Kim Mie-Jin;Jo Hey-Sook;Yeum Yun-Kyung;Yu Ju-Hee;Lee Yong-Tae;Ji Gyue-Yong;Kim Gyue-Gon;Lee In-Sun
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.19 no.5
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    • pp.1146-1153
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    • 2005
  • This study was investigated so that reliability of disease mechanism diagnosis would be examined, the estimation about disease mechanism item of Questionnaires and the relations of disease mechanism would be inquired about 'health diagnosis program' Questionnaires which were used for the object diagnosis of Oriental medicine in the department of Oriental OB&GY, Oriental Medical hospital of Dong-Eui University. We analyzed the results of Questionnaires for 3354 outpatients who had OB & GY disease in the Oriental Medical hospital of Dong-Eui University from April 2000 to March 2004. The diagnosis Questionnaires(after DSOM (r) S.1.1) was the figures 188, the health diagnosis Questionnaires (after DSOM (r) S.1.1) was the figures 137. phiegm deficiency of qi was used in DSOM (r) R.1.1 as it is. The reliability of DSOM (r) S.1.1 was usually higher than DSOM (r) R.1.1 in deficiency of qi blood stasis insufficiency of Yang heat syndrom damp, 5 case disease mechanism. The reliability of DSOM (r) S.1.1 was usually lower than DSOM (r) R.1.1 in blood deficiency stagnation of qi coldness damp dryness liver heart spleen kidney, 8 case disease mechanism. but the great difference wasn't seen, therefore both DSOM (r) S.1.1 and DSOM (r) R.1.1 had similar result. A meeting point both DSOM (r) S.1.1 and DSOM (r) R.1.1 was above 90% in liver spleen blood stasis blood deficiency, 4 case disease mechanism with the exception of phlegm deficiency of Yim nothing of fluctuations of question. A meeting point of coldness that was 82.47% was lowest, A meeting point of the rest disease mechanism was above 85%. The effect that contributed in producing disease mechanism result and in which pure question was over relevance calculation 0.9, insufficiency of Yang damp phlegm that contributed in producing disease mechanism result was lower comparatively in DSOM (r) R.1.1. But the effect that contributed in producing disease mechanism result and in which pure question was over relevance calculation 0.9 except spleen kidney phlegm in DSOM (r) S.1.1

Variation of Soil Mycoflora in Decomposition of Rice Stubble from Rice-wheat Cropping System

  • Vibha, Vibha;Sinha, Asha
    • Mycobiology
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    • v.35 no.4
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    • pp.191-195
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    • 2007
  • The colonization pattern and extent of decay produced in paddy stubble by soil inhabiting mycoflora were done by using nylon net bag technique. Among the three methods used for isolation of fungi, dilution plate technique recorded the highest number of fungi followed by damp chamber and direct observation method. Nutrient availability and climatic conditions (temperature, humidity and rainfall) influenced the occurrence and colonization pattern of fungi. Maximum fungal population was recorded in October ($48.99{\times}10^4/g$ dry litter) and minimum in May ($11.41{\times}10^4/g$ dry litter). Distribution of Deuteromycetous fungi was more in comparison to Zygomycetes, oomycetes and ascomycetes. In the early stage of decomposition Mucor racemosus, Rhizopus nigricans, Chaetomium globosum and Gliocladium species were found primarly whereas at later stages of decomposition preponderance of Aspergillus candidus, Torula graminis, Cladosporiun cladosporioides and Aspergillus luchuensis was recorded.

Anti-apoptotic Effects of House Dust Mite, S100A8 and S100A9 on Spontaneous Apoptosis of Neutrophils in Coculture with Immune Cells and in the Presence of T Helper Cytokines

  • Kim, In Sik;Lee, Ji-Sook
    • Biomedical Science Letters
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    • v.21 no.2
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    • pp.122-125
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    • 2015
  • House dust mite (HDM) as a major allergen and damage-associated molecular pattern (DAMP) such as S100A8 and S100A9 trigger the pathogenesis and severity of allergic disease such as asthma. Regulation of neutrophil apoptosis is an important immune response and its dysregulation is involved in pathogenesis of allergic diseases. In this study, we examined the effects of HDM, S100A8 and S100A9 on spontaneous apoptosis of normal neutrophils. We considered the importance of the difference between in vitro and in vivo results and developed a new in vitro system consisting of a combination of immune cells and T helper (Th) cytokines. Extract of Dermatophagoides pteronyssinus (DP), S100A8, and S100A9 inhibited neutrophil apoptosis in culture of neutrophils alone without other leukocytes. DP and S100A8 more strongly suppressed neutrophil apoptosis in combinations of neutrophils, eosinophils, lymphocytes or monocytes than in a culture of neutrophils alone. Anti-apoptotic effect of S100A9 in the mixture of immune cells was similar to that in neutrophils. DP, S100A8, and S100A9 blocked neutrophil apoptosis, regardless of pretreatment with a T helper (Th) 1 cytokine (IFN-$\gamma$), Th2 cytokines (IL-4 and IL-10), a Th9 cytokine (IL-9), a Th17 cytokine (IL-17), a Treg-producing cytokine (TGF-$\beta$). These findings may enable elucidation of allergy pathogenesis due to HDM and DAMP.