• Title/Summary/Keyword: 3Screen

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Herbicidal activity of Korean native plants (II) (살초활성물질 함유 국내 자생식물의 탐색 (II))

  • Kim, Mi-Sung;Lee, Yu-Sun;Khoa, Dao Bach;Kim, Hee-Yeon;Choi, Hae-Jin;Lim, Sang-Hyun;Heo, Su-Jeong;Kwon, Soon-Bae;Park, Dong-Sik;Han, Sang-Sub;Kim, Song-Mun
    • The Korean Journal of Pesticide Science
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    • v.8 no.3
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    • pp.220-230
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    • 2004
  • This study was conducted of Korean native plants to screen herbicidal activity which could be used for the development of new natural herbicides. Ninety-eight plants were collected from Wan Island, Chollanamdo in Korea and their methanol extracts were obtained. Herbicidal activities of the methanol extracts were determined by seed bioassay using canola (Brassica napus L.) seedlings. Among ninety-eight species, twenty plants were highly herbicidal ($GR_{50}<1,000\;{\mu}g\;g^{-1}$): Abies holophylla MAXIM., Ailanthus altissima (MILL.) SWINGLE, Anthemis nobilis L., Aralia elata SEEM., Artemisia iwayomogi KITAMURA, Asarum sieboldii MIQ., Brassica campestris subsp. napus var. nippo-oleifera MAKINO, Clematis terniflora DC., Crataegus scabrida SARG., Gnaphalium affine D. DON, Jasminum nudiflorum LINDL., Kalopanax pictus (THUNE.) NAKAI, Machilus japonica S. et Z., Myrica rubra S. et Z., Osmunda japonica THUNB., Phytolacca esculenta V. Houtte, Platanus occidentalis L., Quisqualis indica L., Rubus hirsutus THUNB., Yucca smalliana FERN. Fifty plants were shown moderate herbicidal activity $(1,000\;{\mu}g\;g^{-1}, however, twenty-eight plants were not shown any herbicidal activity.

Removal of Impurities by Magnetic Separation from Waste Fluidized Cracking Catalyst for Its Reuse (폐FCC 촉매의 재활용 과정에서 자력 선별법에 의한 불순물 제거 연구)

  • Ban Bong-Chan;Lee Jin-Suk;Kim Dong-Su
    • Resources Recycling
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    • v.12 no.1
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    • pp.55-64
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    • 2003
  • Presently, the reuse of waste FCC catalysts, which generated from the refining process of crack oil, after the removal of con-taminated metallic impurities have not been attempted domestically yet because the separation technology f3r the impurities from waste catalysts has not been established. As a basic study far the reusable portion from the waste FCC catalysts and treatment of metallic impurities are assured, there will be invoked an significant contribution not only in the recycling of abandoned wastes up to date but also in the treatment efficiency of wastes and extraction of economical benefits from them. The magnetic separation of impurities such as Fe, Ni, and V, from waste FCC catalyst has been attempted with or without its pre-oxidation at high temperature for the purpose of its reuse. The results showed that the separability of impurities by magnetic force was high far non-preoxidized catalysts compared with preoxidized ones, and employment of screen-type matrix showed a higher separation efficiency than ball-type matrix. The separability increased with the strength of magnetic field, and the method of ball matrix has separation efficiency of maximum 51.10%. The amount of metallic impurities was in the decreasing order of V, Ni, and Fe depending upon ICP analysis.

An ELISA-on-a-Chip Biosensor System for Early Screening of Listeria monocytogenes in Contaminated Food Products

  • Seo, Sung-Min;Cho, Il-Hoon;Kim, Joo-Ho;Jeon, Jin-Woo;Oh, Eun-Gyoung;Yu, Hong-Sik;Shin, Soon-Bum;Lee, Hee-Jung;Paek, Se-Hwan
    • Bulletin of the Korean Chemical Society
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    • v.30 no.12
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    • pp.2993-2998
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    • 2009
  • An enzyme-linked immunosorbent assay (ELISA)-on-a-chip (EOC) biosensor combined with cell concentration technology based on immuno-magnetic separation (IMS) was investigated for use as a potential tool for early screening of Listeria monocytogenes (L. monocytogenes) in food products. The target analyte is a well-known pathogenic foodborne microorganism and outbreaks of the food poisoning typically occur due to contamination of normal food products. Thus, the aim of this study was to develop a rapid and reliable sensor that could be utilized on a daily basis to test food products for the presence of this pathogenic microorganism. The sensor was optimized to provide a high detection capability (e.g., 5.9 ${\times}\;10^3$ cells/mL) and, to eventually minimize cultivation time. The cell density was condensed using IMS prior to analysis. Since the concentration rate of IMS was greater than 100-fold, this combination resulted in a detection limit of 54 cells/mL. The EOC-IMS coupled analytical system was then applied to a real sample test of fish intestines. The system was able to detect L. monocytogenes at a concentration of 2.4 CFU/g after pre-enrichment for 6 h from the onset of cell cultivation. This may allow us to monitor the target analyte at a concentration less than 1 CFU/g within a 9 h-cultivation provided a doubling time of 40 min is typically maintained. Based on this estimation, the EOC-IMS system can screen and detect the presence of this microorganism in food products almost within working hours.

Injury of Full Seed Stage Soybeans by The Bean Bug, Riptortus pedestris (콩 종실비대성기에 톱다리개미허리노린재 가해에 의한 피해 해석)

  • Jung, Jin-Kyo;Seo, Bo-Yoon;Youn, Jong-Tag;Park, Jong-Ho;Cho, Jum-Rae
    • Korean journal of applied entomology
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    • v.49 no.4
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    • pp.357-362
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    • 2010
  • Soybean seed injury was analyzed in the experiments in which the bean bug, Riptortus pedestris(Hemiptera: Alydidae), was released into screen-caged pots containing full seed stage(R6) of soybean. When the different stages of insects, from the 3rd instar nymphs to adults, were released into pots during 8 days in soybean R6 stage, soybean seeds with injury marks (B-type seeds) increased. The weight reduction ratio in B-type seeds was highest in the injury by the 5th instar nymphs, while the daily-produced number ratio of B-type seeds was small in the treatment. In the injury by the different number of adult released into pots, 4, 8, 16 adults caused a significant increase of B-type seeds, while 16 adults caused the significant increase of the deformed (C-type) seeds. In the injury by the different release period of adults, the total number of pods was not significantly different among treatments, while the total seed number harvested was significantly small in the release for 48 days. The release for 8 and 16 days caused a significant increase of B-type seeds, while the release for 48 days caused the increase of C-type seeds. The results indicated that injury of soybean R6 stage by the bean bug produced soybean seeds with distinct injury marks at relatively low density and during short term attack period, while it produced deformed seeds at high density and during long attack period.

Development of Parental Screening Questionnaire for Hidden Youth (부모 작성용 은둔형 외톨이 선별 도구 개발)

  • Baek, Hyung-Tae;Kim, Boong-Nyun;Shin, Min-Sup;Ahn, Dong-Hyun;Lee, Young-Sik
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.22 no.4
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    • pp.262-270
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    • 2011
  • Objectives : The definition of a hidden youth is a young person who has completely withdrawn from society and shut himself or herself away for more than 3 months. Those pathologically-withdrawn youths have become a burden not only to society but also to the family. However, screening of these hidden youths cannot be done easily. This study focused on developing a primary effective screening tool for these hidden youths. Methods : The 42 participants of this study were parents of hidden youths that are between 8 to 25 years old. They were selected from from mental health centers and psychiatric clinics around Seoul and Gyeonggi Province. We also recruited 239 parents of middle and high school students in the Seoul metropolitan area for a control group. In order to decide the concurrent validity of this questionnaire, we used the Symptom Checklist-90-Revision, Children's Depression Inventory, Beck Depression Inven-tory, Social Anxiety Scale for Children-Revised, Social Anxiety and Distress Scale, Avoidant Personality Disorder Scale, and State-Trait Anxiety Inventory for Children. SPSS version 12.0 was used for statistical analysis. Results : Cronbach's alpha values, the reliability coefficient to represent internal consistency, were between 0.396 and 0.935, which showed relatively high internal consistency for this questionnaire. The test-retest coefficient was between 0.68 and 0.78, which was a statistically significant result. In a factor analysis, 4 factors such as avoidance, withdrawal, isolation, and apathy were extracted. In a concurrent validity test with SCL-90-R, the isolation factor showed a statistically-significant relationship with a phobic-anxiety sub-scale, and avoidance and withdrawal sub-scales were remarkably correlated with the interpersonal sensitivity sub-scale. Conclusion : Since the questionnaire for socially withdrawn youths has achieved statistically-satisfactory reliability and validity, it will be a useful method to screen for hidden youths in educational, community, and clinical settings.

An Implementation of the Report View Generator using Program Performance Log Information (프로그램 성능 평가 로그 정보를 이용한 레포트 뷰 생성기 구현)

  • Cho Yong-Yoon;Yoo Chae-Woo
    • Journal of the Korea Society of Computer and Information
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    • v.10 no.3 s.35
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    • pp.35-44
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    • 2005
  • A software developer can use a performance evaluation tool to elevate development speed and improve qualify of softwares. But, evaluation results that most performance evaluation tools offer are complicated strings. Therefore, a developer cannot intuitively understand the meanings of the results and must make much times and efforts in analysing the result. In this paper, we propose a report view generator that can transform and provide the text-based performance evaluation results for softwares with various graphic-based views. Our proposed generator consists of a screen generator that creates a structural XML document about the text-based performance evaluation results and a log analyzer that makes various report view through the created XML evaluation document. Because the XML evaluation result document can express the result information structured according to performance evaluation items for resources of softwares, it can have flexibility in offering and integrating the result information for the items. Through the suggested report view generator, developers can intuitively understand and analysis performance evaluation results of embedded software. And they can easily and quickly improve software quality and improve development efficiency of softwares.

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Expression of MEK1 Fusion Protein in Yeast for Developing Cell Based Assay System, a Major Substrate of LeTx (Yeast내에서 MEK1 융합 단백질 발현 및 Lethal Factor 활성 검증)

  • Hwang, Hye-Hyun;Kim, Joung-Mok;Choi, Kyoung-Jae;Park, Hae-Chul;Han, Sung-Hwan;Chung, Hoe-Il;Koo, Bon-Sung;Park, Joon-Shik;Yoon, Moon-Young
    • Korean Journal of Microbiology
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    • v.42 no.3
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    • pp.195-198
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    • 2006
  • Lethal toxin is a critical virulence factor of anthrax. It is composed two protein: protective antigen (PA) and lethal factor (LF). PA binds to specific cell surface receptors and, forms a membrane channel that mediates entry of LF into the cell. LF is a zinc-dependent metalloprotease, which cleaves MKKs [MAPK (mitogen-activated protein kinase) kinases] at peptide bonds very close to their N-termini. In this study, we suggest application of cell-based assays in the early phase of drug discovery, with a particular focus on the use of yeast cells. We constructed MEK1 expression system in yeast to determine LF activity and approached cell-based assay system to screen inhibitors, in which the results covering the construction of LF-substrate in yeast expression vector, expression, and LF-mediated proteolysis of substrate were described. These results could provided the basic steps in design of cell-based assay system with the high efficiency, rapidly and easy way to screening of inhibitors.

Diagnostic Accuracy of Cervicovaginal Cytology in the Detection of Squamous Epithelial Lesions of the Uterine Cervix; Cytologic/Histologic Correlation of 481 Cases (자궁경부 편평상피병변에서 자궁경부질도말 세포검사의 진단정확도 : 481예의 세포-조직 상관관계)

  • Jin, So-Young;Park, Sang-Mo;Kim, Mee-Sun;Jeen, Yoon-Mi;Kim, Dong-Won;Lee, Dong-Wha
    • The Korean Journal of Cytopathology
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    • v.19 no.2
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    • pp.111-118
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    • 2008
  • Background : Cervicovaginal cytology is a screening test of uterine cervical cancer. The sensitivity of cervicovaginal cytology is less than 50%, but studies of cytologic/histologic correlation are limited. We analyzed the diagnostic accuracy of cervicovaginal cytology in the detection of the squamous epithelial lesions of the uterine cervix and investigate the cause of diagnostic discordance. Materials and Methods : We collected a total of 481 sets of cervicovaginal cytology and biopsies over 5 years. The cytologic diagnoses were categorized based on The Bethesda System and the histologic diagnoses were classified as negative, flat condyloma, cervical intraepithelial neoplasia (CIN) I, CIN II, CIN III, or squamous cell carcinoma. Cytohistologic discrepancies were reviewed. Results: The concordance rate between the cytological and the histological diagnosis was 79.0%. The sensitivity and specificity of cervicovaginal cytology were 80.6% and 92.6%, respectively. Its positive predictive value and negative predictive value were 93.7% and 77.7%, respectively. The false negative rate was 19.4%. Among 54 false negative cytology cases, they were confirmed by histology as 50 flat condylomas, 2 CIN I, 1 CIN III, and 1 squamous cell carcinoma. The causes of false negative cytology were sampling errors in 75.6% and interpretation errors in 24.4%. The false positive rate was 7.4%. Among 15 false positive cytology cases, they were confirmed by histology as 12 atypical squamous cells of undetermined significance (ASCUS) and 3 low grade squamous intraepithelial lesions (LSIL). The cause of error was interpretation error in all cases. The overall diagnostic accuracy of cervicovaginal cytology was 85.7%. Conclusions : Cervicovaginal cytology shows high overall diagnostic accuracy and is a useful primary screen of uterine cervical cancer.

A Study on Hierarchy Analysis of Design Factors for Product Development Process (신제품 개발과정에 있어서의 디자인요소 분석을 통한 계층화 연구)

  • 곽대영
    • Archives of design research
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    • v.17 no.1
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    • pp.163-178
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    • 2004
  • In this study, in order to achieve the before-mentioned study purpose, the importance of developing the new product, the relationship with the design, and the design element for developing the new product were considered. In order to extract the importance of the design element which is applied to the development of the new product design, the research model about the induction of the priority was created, the evaluation items were instituted, and the demonstrative research approach was performed in order to recognize the relationship among those elements. Firstly, in the process of selecting the items for the application, 14 evaluation elements which were extracted through the advanced study data were grouped in 4 kinds of dimensions, and the properties which are related with the Digital TV product were composed up of 36 items. Through the factor analysis, by decreasing the detailed standard for the evaluation of 36 items, the parsimony was secured, and the characteristics which the various items contain induced into one factor. Secondly, the detailed factors which were united into one factor went under the paired comparison as one by one through AHP again, and then the importance degree was generated. First of all, as the first stage of AHP, the decision making factors which affect the whole achievement of purpose of the decision making were classified as in a hierarchical style. From these research results, it was known that the functional factor and esthetic factor in the process of designing the new product are the major affecting variables, and it was confirmed that in case of the Digital TV products group, the factors such as the high quality of picture, big screen, user interface, sound, product reliability, style, size, indoor reproduction, and guarantee are the main factors which influence the need of the consumers in purchasing products.

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Study on the optimal design of floor exhaust system using computational fluid dynamics for subway platform (수치해석을 활용한 승강장 바닥배기 시스템 최적화 연구)

  • Namgung, Hyeong-Gyu;Park, Sechan;Kim, Minhae;Kim, Soo-Yeon;Kwon, Soon-Bark
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.2
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    • pp.443-449
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    • 2017
  • The imbalance of air supply and the exhaust on subway platforms has led to the installation of platform screen doors in underground subway stations. This imbalance causes the accumulation of pollutants on the platform and loss of comfort due to the lack of ventilation. In this study, a floor exhaust system was optimized using computational fluid dynamics (CFD) and an optimization program. The optimized floor exhaust system was manufactured and tested experimentally to evaluate the particle collection efficiency. CFX 17.0 and HEEDS were used to analyze the flow field and optimize the principal dimensions of the exhaust system. As a result of the three-step optimization, the optimized floor exhaust system had a total height of 1.78 m, pressure drop of 430 Pa, and particle collection capability of 61%. A fine dust particle collection experiment was conducted using a floor exhaust system that was manufactured at full scale based on the optimized design. The experiment indicated about 65% particle collection efficiency. Therefore, the optimized design can be applied to subway platforms to draw in exhaust air and remove particulate matter at the same time.