• Nuclear Engineering and Technology
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• 제48권3호
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• pp.608-612
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• 2016

D-(+)-glucose (Glc) was added to the original Fricke polyvinyl alcohol-glutaraldehyde-xylenol orange (FPGX) hydrogel dosimeter system to make a more stable FPGX hydrogel three-dimensional dosimeter in this paper. Polyvinyl alcohol was used as a substrate, which was combined with Fricke solution. Various concentrations of Glc were tested with linear relevant fitting for optimal hydrogel production conditions. The effects of various formulations on the stability and sensitivity of dosimeters were evaluated. The results indicated that D-(+)-Glc, as a free radical scavenger, had a great effect on stabilizing the dose response related to absorbency and reducing the auto-oxidization of ferrous ions. A careful doping with Glc could slow down the color change of the dosimeter before and after radiation without any effect on the sensitivity of the dosimeter.

• 한국산업보건학회지
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• 제5권2호
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• pp.193-199
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• 1995

This study was designed to investigate the difference of time weighted average(TWA) of noise levels and noise doses by the different operating parameter settings such as exchange rate, threshold level and criterion level for noise dosimeter in the field measurements of noise at industrial working environments. The time weighted averages of noise level and noise doses for noise working environments were determined by noise dosimeter on 80 workers employed at 20 industrial establishments of 8 industries. The results obtained were as follows: 1. The mean time weighted average(TWA) of the noise working environments by the operating parameter settings showed 93.4 dB(A) in 3 dB of exchange rate, 80 dB of threshold level and 90dB of criterion level 92.0 dB(A) in 3 dB-exchange rate, 90 dB-threshold level and 90 dB-criterion level, in 90.8 dB(A) in 5 dB of exchange rate, 80 dB of threshold level and 90 dB of criterion level, and 86.7 dB(A) in 5 dB of exchange rate, 90 dB of threshold level and 90dB of criterion level. 2. ln group of noise level less than 90 dB(A), mean TWAs of 80 dB of threshold level were significantly higher than that of 90 dB of threshold level in 3 dB and 5 dB of exchange rate. 3. The case exceeded threshold limit value of noise was 49(61.3 %) in 3dB, 80dB and 90 dB setting, 44(55.0 %) in 3 dB, 90 dB, 90 dB setting, 33(41.3 %) in 5 dB, 80dB, 90 dB setting and 26(32.5%) in 5 dB, 90 dB, 90 dB setting. Above considerations in mind, it is suggested that exchange rate and threshold level be specified in related laws and regulations in the evaluation of working environments noise.

• Journal of Microbiology and Biotechnology
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• 제11권3호
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• pp.524-528
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• 2001

The measurement of radiation response using simple and informative techniques would be of great value in studying the genetic risk following occupational, therapeutic, or accidental exposure to radiation. When patients receive radiation therapy, many suffer from side effects. Since each patient receives a different dose due to different physical conditions, it is important to measure the exact dose of radiation received by each patient to lessen the side effects. Even though several biological dosimetric systems have already been developed, there is no ideal system that can satisfy all the criteria for an idean dosimetric system, especially for low-dose radiation as used in radiation therapy. In this study, an SOS Chromotest of E. coli PQ37 was evaluated as a novel dosimeter for low-dose gamma-rays. E. coli PQ37 was originally developed to screen chemical mutagens using the SOS Chromotest-a colorimtric assay, based on the induction of ${\beta}$-galactosidase ue to DNA damage. The survival fraction of E. coli PQ37 decreased dose-dependently with an increasing dose of cobalt-60 gamma-rays. Also, a good linear correlation was found between the biological damage revealed by the ${\beta}$-galactosidase expression and the doses of gamma-rays. The expression of ${\beta}$-galactosidase activity that responded to low-dose radiation under 1 Gy was $Y=0.404+(0.089{\pm}0.3)D+(-0.018{\pm}0.16)D^2$ (Y, absorbance at 420 nm; D, Dose of irradiation) as calculated using Graph Pad In Plot and Excel. When a rabbit was fed with capsules containing an agar block embdded with E. coli PQ37 showed a linear response to the radiation doses. Accordingly, the results confirm that E. coli PQ37 can be used as a sensitive biological dosimeter fro cobalt-60 gamma-rays. To the best of our knowledge, this is the first time that a bacterium has been used as a biological dosimeter, especially for low-dose radiation.

• Nuclear Engineering and Technology
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• 제52권10호
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• pp.2334-2338
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• 2020

In recent years, 3D printing technology has received significant research attention. Additionally, 3D printing technology is being applied to study radiation dosimeters of various materials. In this study, a plastic scintillator for 3D printing was developed in a laboratory and used to manufacture a plastic scintillation dosimeter (PSD) with a shape identical to that of the ionization chamber PTW31010. The 16-mm beam of Gamma Knife® Perfexion™ was irradiated to derive the absorbed dose rates of the PSD and PTW31010; they were subsequently compared with the dose rates of the treatment plan. The differences in the dose rates of the Gamma Knife treatment plan and the absorbed dose rates of PTW31010 were within 0.87%. The difference between the dose rates of the Gamma Knife treatment plan and the absorbed dose rates of the PSD were within 4.1%. A linear fit of the absorbed dose rates of four shots involving different dose rates and irradiation angles yielded an adjusted R-square value exceeding 0.9999. A total of 10 repeated measurements were conducted for the same shot to confirm its reproducibility, with a relative error of 0.56%.

• Journal of Radiation Protection and Research
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• 제31권2호
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• pp.97-104
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• 2006

최근 방사선 치료 및 진단 분야에서 선량 측정을 위하여 다양하게 사용되고 있는 MOSFET 선량계는 검출부위가 실리콘으로 이루어져 있으며 다른 검출기들과 마찬가지로 어느 정도의 에너지 의존도와 방향 의존도를 보인다. 따라서 MOSFET 선량제가 공기 중이 아닌 모의피폭체 내에서 선량 측정에 사용될 경우 낮은 에너지를 갖는 산란 광자 등 이차 광자들로 인하여 선량을 실제보다. 높게 평가하게 된다. 본 연구에서는 MOSFET 선량계의 에너지 의존도와 방향 의존도로 인하여 발생하는 오차를 보정하기 위한 선량보정인자를 몬테카를로 전산모사 기법을 이용하여 계산하였다. 먼저 사용되는 인형 모의 피폭체의 체적소 모의피폭체(Voxel Phanom)를 CT 영상을 이용하여 제작하였으며 제작된 체적소 모의 피폭체를 몬테카를로 전산코드로 구현한 후, 모의피폭체 내 각 선량계 지점에서 입사하는 광자의 에너지 및 방향별 에너지 스펙트럼을 계산하였다. 각각의 선량계 지점에서 0.662 MeV와 1.25 MeV의 광자빔을 고려하였으며 또한 MOSFET 선량계의 방향은 실리콘 베이스 방향과 에폭시 방향을 고려하였다. 주어진 선량제 지점에서의 선량보정인자는 계산된 에너지 의존도들의 중간간을 이용하여 결정하였으며 이렇게 결정된 각 선량계 지점에서 선량보정인자는 0.89-0.97 범위의 값들을 나타내었다. 본 연구결과에 따르면 MOSFET 선량계를 이용하여 인형 모의피폭체 내에 선량을 측정할 때 에너지 의존도와 방향 의존도를 고려하지 않을 경우 측정 위치에 따라 $3{\sim}11%$ 정도의 측정오차가 발생할 수 있다. 그러므로 인형 모의피폭체 내의 선량을 정확하게 측정하기 위해서는 선량보정인자를 각 선량계에 필히 적용해주어야 한다.

• 한국산업보건학회지
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• 제33권3호
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• pp.308-316
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• 2023

Objectives: The aim of this study is to measure and assess the occupational noise exposure levels among construction workers at apartment building construction sites in South Korea. Methods: Noise exposure assessments were conducted for 139 construction workers across 10 different trades at 53 apartment building construction sites in the northern part of Gyeonggi-do. Assessments were carried out using a noise dosimeter set with a 90 dB criterion, an 80 dB threshold, and a 5 dB exchange rate over a period of more than 6 hours(L_MOEL) Results: The mean L_MOEL (equivalent continuous noise level over 8 hours) for the 139 dosimeter samples was 87.8 ± 4.3 dBA. The mean noise exposure level for each construction trade, referred to as the trade mean, was also calculated. Significant differences in noise exposure levels were observed between construction trades (ANOVA, p < 0.001). The highest L_MOEL values were recorded for concrete chippers (93.2 ± 2.6 dBA), followed by ironworkers (88.4 ± 0.7 dBA), concrete finishers (88.3 ± 2.7 dBA), masonry workers (87.7 ± 1.9 dBA), pile driver operators (85.6 ± 1.7 dBA), concrete carpenters (84.9 ± 2.4 dBA), interior carpenters (83.5 ± 2.1 dBA), and other groups (81.4 ± 2.2 dBA). Conclusions: The findings suggest that nearly all construction workers in this study are at risk of Noise-Induced Hearing Loss (NIHL). Moreover, the study establishes that construction trades can serve as a useful metric for assessing noise exposure levels at apartment construction sites.

• Journal of the Korean Physical Society
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• 제73권10호
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• pp.1571-1576
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• 2018

We developed and evaluated an algorithm to calculate the target radiation dose in cancer patients by measuring the transmitted dose during 3D conformal radiation treatment (3D-CRT) treatment. The patient target doses were calculated from the transit dose, which was measured using a glass dosimeter positioned 150 cm from the source. The accuracy of the transit dose algorithm was evaluated using a solid water phantom for five patient treatment plans. We performed transit dose-based patient dose verification during the actual treatment of 34 patients who underwent 3D-CRT. These included 17 patients with breast cancer, 11 with pelvic cancer, and 6 with other cancers. In the solid water phantom study, the difference between the transit dosimetry algorithm with the treatment planning system (TPS) and the measurement was $-0.10{\pm}1.93%$. In the clinical study, this difference was $0.94{\pm}4.13%$ for the patients with 17 breast cancers, $-0.11{\pm}3.50%$ for the eight with rectal cancer, $0.51{\pm}5.10%$ for the four with bone cancer, and $0.91{\pm}3.69%$ for the other five. These results suggest that transit-dosimetry-based in-room patient dose verification is a useful application for 3D-CRT. We expect that this technique will be widely applicable for patient safety in the treatment room through improvements in the transit dosimetry algorithm for complicated treatment techniques (including intensity modulated radiation therapy (IMRT) or volumetric modulated arc therapy (VMAT).

• Journal of Radiation Protection and Research
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• 제44권2호
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• pp.79-88
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• 2019

Background: The main goal of experiments is to compare various operational and technical characteristics of D-Shuttle semiconductor personal dosimeters of the Japanese company "Chiyoda Technol Corporation" and Harshaw thermoluminescent dosimeters (TLD) manufactured by "Thermo Fisher Scientific" and DTL-02 of the Russian Research and Production Enterprise (RPE) "Doza" by their occupational and calibration exposure at various dose equivalents from 0.5 to 20 mSv of gamma-radiation. Materials and Methods: Besides dosimeters DTL-02, D-Shuttle and Harshaw TLD, there were also used: (1) the primary reference radionuclide source Hopewell Designs IAEA: G10-1-12 with $^{137}Cs$ isotope (an error is not more than 6% and activity is 20 Ci), and (2) the verification device UPGD-2M of RPE "Doza" and installed in the National Center for Expertise and Certification of the Republic of Kazakhstan (Kapchagai, the National Center for Expertise and Certification). Results and Discussion: The main results of researches are the following: (1) TLDs for Harshaw 6600 and DVG-02TM have an approximately equal measurement accuracy of the individual dose equivalents in the range from 0.5 to 20 mSv of gamma-radiation. (2) Advantages of dosimeters for Harshaw 6600 are due to the high measurement productivity and opportunity to indicate the dose on the skin $H_p$(0.07). Advantages of DVG-02TM consist of operation simplicity and lower cost than of Harshaw 6600. (3) D-Shuttles are convenient for use in the current and the operational monitoring of ionizing radiation. Measurement accuracy and 10% linearity of measurements are ensured when D-Shuttle is irradiated with dose equivalents below 1 mSv at the equivalent dose rate not higher than $3mSv{\cdot}hr^{-1}$. This allows using D-Shuttle at a routine technological activity. Conclusion: The obtained results of experiments demonstrate advantages and disadvantages of D-Shuttle semiconductor dosimeters in comparison with two TLD systems of DVG-02TM and Harshaw 6600.

• 한국의학물리학회지:의학물리
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• 제23권1호
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• pp.54-61
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• 2012

중합체 겔 선량계를 제작하여 사이버나이프의 광자선의 소조사면에서의 3차원적 선량측정 실험을 수행하였다. 겔 선량계는 아크릴로 제작된 두경부 팬텀내에 설치하여 선량측정에 사용하였다. 두경부 팬텀의 영상은 사이버나이프의 두경부 환자 치료를 위해 사용하는 전산화단층촬영장치(CT)의 프로토콜을 사용하여 획득하였고 치료계획 시스템에 전달되었다. 겔 선량계에 치료계획에서 수립한 방사선을 조사하였으며, 24시간 경과 후에 선량분석을 위하여 3.0T 자기공명영상장치(MRI)로 영상을 획득하였다. 측정된 겔 팬텀의 선량분포는 MATLAB을 이용하여 분석하였고 측정된 결과를 치료계획에서의 계산값과 비교하였다. 선량분포는 축상(axial) 방향의 등선량곡선의 80% 고선량 영역에서 치료계획 선량곡선과 측정된 선량곡선과의 차이가 0.76 mm이었으며, 40% 저선량 영역에서는 차이가 1.29 mm로 저선량 영역보다 고 선량영역에서 잘 일치함을 알 수 있었다. 본 연구에서 중합체 겔 선량계와 자기공명영상을 이용하여 소조사면에 대해 3차원적으로 선량을 분석할 수 있을 뿐 아니라 치료방사선 정도관리에도 활용될 수 있는 가능성을 확인하였다.

• 한국산업보건학회지
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• 제11권3호
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• pp.190-197
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• 2001

Noise-induced hearing loss(NIHL) was the highest rate (43.5%~58.5% from 1996 to 1998) of positive findings through specific medical program in Korea. There were much more NIHL at workers of automobile manufacturing factories than other manufacturing factories. The specific aim of the present study was to determine the noise exposure of automobile press lines, according to their job titles, press line types(auto, semiauto), dosimeter parameters setting. There were a total 11 press lines sampled at a automobile manufacturing company. Among those press lines, 10 press lines were autolines with acoustic enclosure, one semiauto press line was no aucostic enclosure Noise exposure data were sampled for an work shift using noise dosimeter, which recorded both time-weighted average(TWA) and 1-min average. The mean OSHA TWA(Korea TWA with threshold 90) was $80.7dB(A){\pm}4.7dB(A)$ for leader, $82.8dB(A{\pm}4.5dB(A)$ for pallette man, $76.7dB(A){\pm}4.3dB(A)$ for press operators, $76.6dB(A){\pm}5.6dB(A)$ for crane operators, $77.1dB(A){\pm}2.8dB(A)$ for forklift drivers, whereas the mean NIOSH TWA was $88.9dB(A){\pm}1.7dB(A)$ for leader, $89.6dB(A){\pm}2.1dB(A)$ for pallette man, $86.7dB(A){\pm}1.8dB(A)$ for press operators, $88.5dB(A){\pm}2.0dB(A)$ for crane operators, $87.7dB(A){\pm}1.0dB(A)$ for forklift drivers. While L10 for NIOSH TWA samples was 84.8 dB(A) ~ 87.3 dB(A), L10 for OSHA TWA samples was 69.5 dB(A) ~ 77.4 dB(A). L10 means that the TWA for 90% of the samples exceeded L10. Among OSHA TWA(Korea TWA with threshold 90) samples for pallette man, 7.7 % exceeded 90 dB(A), the OSHA permissible exposure level, but OSHA TWA samples for the other job titles didn't. Among NIOSH TWA samples, the samples over 85 dB(A), the NIOSH recommended exposure limit, was 100% (leaders), 83.3 %(operators), 97.4%(palletteman), 100%(forklift drivers), 91.7 %(crane operator). The results of One-way random effects analysis of variance models shows that the difference between job titles was significant by OSHA TWA(p<0.05), but not significant by NIOSH TWA(p>0.05). NIOSH TWA samples were significantly higher than OSHA TWA samples(P<0.05). Regression analysis was used to obtain relationships between OSHA TWA samples and NIOSH TWA samples. In this case the coefficient of determination = 0.90, which shows the high degree association between two methods. Regression equation, NIOSH TWA = 0.552 * OSHA TWA + 42.13 dB(A), shows that if OSHA TWA is known, NIOSH TWA can be predicted by the equation. The mean TWA difference between threshold 80 dBA and 90 dBA was significant(p<0.01). While the TWA noise exposures were 7.7% above the Korea(OSHA) PEL, they were more than 83.3% over NIOSH REL. Automobile workers were exposed to noise level that could be potentially damaging to their hearing. It found that there is approximately 25% excess risk of hearing loss even if a worker is protected to the PEL in according to NIOSH study.