• The Journal of Advanced Prosthodontics
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• 제8권5호
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• pp.354-362
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• 2016

PURPOSE. The trueness and precision of acquired images of intraoral digital scanners could be influenced by restoration type, preparation outline form, scanning technology and the application of power. The aim of this study is to perform the comparative evaluation of the 3-dimensional reproducibility of intraoral scanners (IOSs). MATERIALS AND METHODS. The phantom containing five prepared teeth was scanned by the reference scanner (Dental Wings) and 5 test IOSs (E4D dentist, Fastscan, iTero, Trios and Zfx Intrascan). The acquired images of the scanner groups were compared with the image from the reference scanner (trueness) and within each scanner groups (precision). Statistical analysis was performed using independent two-samples t-test and analysis of variance (${\alpha}=.05$). RESULTS. The average deviations of trueness and precision of Fastscan, iTero and Trios were significantly lower than the other scanners. According to the restoration type, significantly higher trueness was observed in crown and inlay than in bridge. However, no significant difference was observed among four sites of preparation outline form. If compared by the characteristics of IOS, high trueness was observed in the group adopting the active triangulation and using powder. However, there was no significant difference between the still image acquisition and video acquisition groups. CONCLUSION. Except for two intraoral scanners, Fastscan, iTero and Trios displayed comparable levels of trueness and precision values in tested phantom model. Difference in trueness was observed depending on the restoration type, the preparation outline form and characteristics of IOS, which should be taken into consideration when the intraoral scanning data are utilized.

• Archives of Pharmacal Research
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• 제29권1호
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• pp.50-58
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• 2006

Translationally controlled tumor protein (TCTP), also known as histamine releasing factor (HRF), is found abundantly in different eukaryotic cell types. The sequence homology of TCTP between different species is very high, belonging to the MSS4/DSS4 superfamily of proteins. TCTP is involved in both cell growth and human late allergy reaction, as well as having a calcium binding property; however, its primary biological functions remain to be clearly elucidated. In regard to many possible functions, the TCTP of Plasmodium falciparum (Pf) is known to bind with an antimalarial agent, artemisinin, which is activated by heme. It is assumed that the endoperoxide-bridge of artemisinin is opened up by heme to form a free radical, which then eventually alkylates, probably to the Cys14 of PfTCTP. Study of the docking of artemisinin with heme, and subsequently with PfTCTP, was carried out to verify the above hypothesis on the basis of structural interactions. The three dimensional (3D) structure of PfTCTP was built by homology modeling, using the NMR structure of the TCTP of Schizosaccharomyces pombe as a template. The quality of the model was examined based on its secondary structure and biological function, as well as with the use of structure evaluating programs. The interactions between artemisinin, heme and PfTCTP were then studied using the docking program, FlexiDock. The center of the peroxide bond of artemisinin and the Fe of heme were docked within a short distance of $2.6{\AA}$, implying the strong possibility of an interaction between the two molecules, as proposed. When the activated form of artemisinin was docked on the PfTCTP, the C4-radical of the drug faced towards the sulfur of Cys14 within a distance of $2.48{\AA}$, again suggesting the possibility of alkylation having occurred. These results confirm the proposed mechanism of the antimalarial effect of artemisinin, which will provide a reliable method for establishing the mechanism of its biological activity using a molecular modeling study.

• Smart Structures and Systems
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• 제29권1호
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• pp.181-193
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• 2022

Data-driven structural health monitoring (SHM) of civil infrastructure can be used to continuously assess the state of a structure, allowing preemptive safety measures to be carried out. Long-term monitoring of large-scale civil infrastructure often involves data-collection using a network of numerous sensors of various types. Malfunctioning sensors in the network are common, which can disrupt the condition assessment and even lead to false-negative indications of damage. The overwhelming size of the data collected renders manual approaches to ensure data quality intractable. The task of detecting and classifying an anomaly in the raw data is non-trivial. We propose an approach to automate this task, improving upon the previously developed technique of image-based pre-processing on one-dimensional (1D) data by enriching the features of the neural network input data with multiple channels. In particular, feature engineering is employed to convert the measured time histories into a 3-channel image comprised of (i) the time history, (ii) the spectrogram, and (iii) the probability density function representation of the signal. To demonstrate this approach, a CNN model is designed and trained on a dataset consisting of acceleration records of sensors installed on a long-span bridge, with the goal of fault detection and classification. The effect of imbalance in anomaly patterns observed is studied to better account for unseen test cases. The proposed framework achieves high overall accuracy and recall even when tested on an unseen dataset that is much larger than the samples used for training, offering a viable solution for implementation on full-scale structures where limited labeled-training data is available.

• 한국건설관리학회논문집
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• 제24권6호
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• pp.63-65
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• 2023

BIM 및 AR 기술은 실제 구조물에 3D 모델 및 정보를 투영하여 현장 내 필요 데이터에 손쉽게 접근할 수 있게 한다는 점에서 건설 산업의 생산성을 증진시킬 수 있을 것으로 평가되어왔다. 그러나 건설 품질관리 업무 내 AR 기술을 적용하기 위한 선행 연구는 대부분 건설 프로젝트 전반을 대상으로 수행되어 총괄적 현장관리 방안에 불과하며, 철근과 같은 부재 단위의 품질관리 내 AR을 적용한 일부 연구 사례 또한 단순 투영에만 집중되어 구체적인 품질점검이 불가한 것으로 확인되었다. 이에 본 연구에서는 철근 부재에 특화된 실무 적용 가능 수준의 BIM 기반 AR 품질관리 시스템 개발을 최종 목적으로 하였다. 본 시스템 개발을 위해 철도 건설 현장에서 활용하는 품질점검 리스트의 철근 점검 항목을 분석하고, 이들을 효과적으로 대응할 수 있는 AR 요소기술 4가지를 개발 및 탑재하였다. 실제 철도 교량 구조물을 대상으로 개발된 시스템을 검증하였으며, 그 결과 투영 안정성 저하 문제가 도출되었다. 이는 모델 경량화(simplification) 및 AR 기기 하드웨어 성능 향상을 통해 해결하였으며, 최종적으로 시스템이 정상적으로 구동되는 것을 확인하였다. 이후 현장 품질 전문가를 대상으로 개발된 철근 품질점검 시스템의 실무 적용성 평가를 실시하였으며, 현행 철근 점검 방식 대비 AR 시스템 활용 시 점검 효율성이 증가할 것으로 평가되었다.

• 한국정보과학회논문지:정보통신
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• 제30권4호
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• pp.559-571
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• 2003

PSTN(Public Switched Telephone Network)과 IP Network의 연동을 제공하는 새로운 프로토콜 ENUM(tElephone Numbering Mapping)은 전 세계적으로 유일성을 가지는 전화번호를 DNS 기반의 구조에서 사용되는 F.Q.D.N.(Fully Qualified Domain Name)으로 변환함으로써 E.164 번호를 사용하여 PSTN에서 제공하는 서비스와 IP 네트워크에서 제공하는 서비스를 동시에 사용 가능케 하는 새로운 인터넷 주소체계이다. 본 논문에서는 미국과 유럽에서 활발히 진행중인 ENUM 모델 표준화 연구 및 개발에 발맞추어 ENUM 기반의 서비스를 사용할 때 ENUM resolution 성능 향상을 위한 Tier 2 네임서버 관리기법을 제시한다. ENUM 위임구조에서 Tier 2 네임서버 제공업자가 지역번호 별로 ENUM 등록 대행업 및 NAPTR RR(Naming Authority PoinTeR 리소스 레코드)을 제공함으로써 ENUM resolution의 성능이 향상됨을 증명하기 위해 ENUM 기반의 네트워크 모델링을 사용하였다. ENUM 프로토콜이 IP 네트워크 사용자와 PST리 사용자에게 유연성 및 편의성을 제공하는 반면 사용자가 ENUM을 사용할 때 지불해야할 인내력을 측정할 척도가 없는 현재 이 논문에서 제안하는 방법은 사용자의 ENUM 서비스 선택 결정에 긍정적인 영향을 미치고, ENUM Tier 2 네임서버 관리를 위한 정책에 도움이 될 것으로 기대된다.