• 디지털융복합연구
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• 제16권6호
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• pp.251-258
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• 2018

종합병원 행정직원의 우울수준(CES-D: Center for Epidemiologic Studies Depression scale)과 관련된 융복합적 요인들을 조사하였다. 설문조사는 2017년 7월 3일부터 2017년 7월 29일까지 임의로 선정된 J지역 9개 종합병원의 재직자 201명에 대하여 무기명 자기기입식 설문지를 사용하였다. 위계적 다중회귀분석 결과, 자아존중감(RES: Rosenberg Self-Esteem Scale)이 낮을수록, 피로(MFS: Multidimensional Fatigue Scale)가 높을수록, 사회심리적 스트레스(PWI-SF: Psychosocial Well-being Index Short Form)가 높을수록 우울이 높았으며 이들의 설명력은 32.5%이었다. 이상의 연구결과를 볼 때, 종합병원 행정직원의 우울수준을 낮추기 위해서는 자아존중감을 높이고, 피로 및 사회심리적 스트레스를 낮추는 노력이 필요하다. 이러한 결과는 종합병원 행정직원의 우울수준을 낮추는 조직인사관리 및 산업보건교육에 활용될 수 있다. 추후연구에서는 종합병원 행정직원의 우울수준에 영향을 미치는 구조방정식 모형의 분석이 필요하다.

• 한국응용과학기술학회지
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• 제18권3호
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• pp.197-213
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• 2001

Conjugate trienoic acids (CTA) occurred in triacylglycerols (TGs) of the seed oils of Trichosanthes kirilowii, Momordica charantia and Aleurites fordii, and they were easily converted to their methyl esters in a mixture of sodium methoxide-methanol without any structural destruction. The main fatty acids in triacylglycerol (TG) fraction of the seed oils of Trichosanthes kirilowii are $C_{18:2{\omega}6}$ (32.2 mol %), $C_{18:3{\;}9c.11t,13c}$ (38.0 mol %) and $C_{18:1{\omega}9}$ (11.8 mol %), followed with $C_{16:0}$ (4.8 mol %) and $C_{18:0}$ (3.1 mol %). The TG fraction was resolved into 20 TG molecular species according to the partition number (PN) by reversed-phase (RP)-HPLC. The main TG species were $DT_{c2}$, $MDT_{c}$ and $D_{2}T_{c}$, of which amounts reached 63 mol % of total TG molecular species. The TG sample was fractionated into 11 fractions according to the number of double bond in the molecule by $Ag^{+}-HPLC$ and the species of $DT_{c2}$, $MDT_{c}$ and $D_{2}T_{c}$ were also eluted as main components. The TG species containing CTA showed unusual behaviours in the order of elution by HPLC ; first, TG moleular species of $DT_{c2}$ (D; dienoic acid, $T_{c}$; punicic acid, $T_{ci}$; ${\alpha}-eleostearic$ acid, M ; monoenoic acid, $S_{t}$; stearic acid) was eluted earlier than $Mt_{c2}$, although they have the same PN number of 40, and, secondly, the species of $DT_{ci2}$ with eight double bonds was eluted earlier than that of $D_2T_{ci}$ with seven double bonds. Intact TG of the seed oils of Momordica charantia contained mainly fatty acids such as $C_{18:3{\omega}9c,11t,13t}$ (57.7 mol %), $C_{18:1{\omega}9}$ (17.4 mol %), $C_{18:0}$ (12.3 mol %) and $C_{18:2{\omega}6}$ (10.6 mol %), and was classified into 13 fractions by RP-HPLC. The main TG species were as follows ; $MT_{ci2}$ [$(C_{18:1{\omega}9})(C_{18:3\;9c,11t,13t})_{2}$, 39.1 mol %] and $S_{t}T_{ci2}$ [$(C_{18:0})(C_{18:3\;9c,11t,13t})_2$, 33.9 mol %] comprising about 73 mol % of total TG species, accompanied by $DT_{ci2}$ [$(C_{18:2{\omega}6})(C_{18:3\;9c,11t,13t})_{2}$, 7.3 mol %], $D_{2}T_{ci}$ [$ (C_{18:2{\omega}6})_{2}(C_{18:3\;9c,11t,13t})$, 3.6 mol %] and $MDT_{ci}$ [$(C_{18:1{\omega}9})(C_{18:2{\omega}6})(C_{18:3\;9c,11t,13t})$, 3.5 mol %]. Simple TG species of $T_{ci3}$ [$(C_{18:3\;9c,11t,13t})_3]$ was present in a small amount of 1.4 mol %, but other simple TG species were not detected. The TG was also resolved into 11 fractions according to the number of double bond by $Ag^{+}-HPLC$, and the species were mainly occupied by $MT_{ci2}$ [$(C_{18:1{\omega}9})(C_{18:3\;9c,11t,13t})_{2}$, 39.4 mol %] and $S_tT-{ci2}$ [$(C_{18:0})(C_{18:3\;9c,11t,13t})_{2}$, 35.4 mol %] $DT_{ci2}$ species with eight double bonds was also developed faster than $D_2T_{ci}$ one with seven double bonds as indicated in the analysis of TG of the seed oils of T. kirilowii, and $MT_{ci2}$ species with cis, trans, trans-configurated double bond was eluted earlier than $MT_{c2}$ species with cis, trans, cis-configurated double bond. The main components of fatty acid in total TG fraction isolated from the seed oils of of Aleurites fordii were in the following order ; $C_{18:3\;9c,11t,13t}$ (81.2 mol %)> $C_{18:2{\omega}6}$ (8.5 mol %)> $C_{18:1{\omega}9}$ (5.4 mol %)$. With resolution of the TG by RP-HPLC, eight fractions such as $T_{ci3}$, $Dt_{ci2}$, $D_{2}T_{ci}$, $MT_{ci2}$, $PT_{ci2}$ (P; palmitic acid), $PMT_{ci}$, $PDT_{ci}$ and $S_{t}T_{ci2}$ ($S_{t}$; stearic acid) were isolated, respectively. TG species of $T_{ci3}$ [$(C_{18:3\;9c,11t,13t})_{3}$, 54.2 mol %], $DT_{ci2}$ [$(C_{18:2{\omega}6})(C_{18:3\;9c,11t,13t})_{2}$, 15.0 mol %] and $MT_{ci2}$ [$(C_{18:1{\omega}9})(C_{18:3 9c,11t,13t})_{2}$, 14.8 mol %] were present as main species.

• Asian-Australasian Journal of Animal Sciences
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• 제30권10호
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• pp.1471-1477
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• 2017

Objective: Since athletic performance is a most importance trait in horses, most research focused on physiological and physical studies of horse athletic abilities. In contrast, the molecular analysis as well as the regulatory pathway studies remain insufficient for evaluation and prediction of horse athletic abilities. In our previous study, we identified AXL receptor tyrosine kinase (AXL) gene which was expressed as alternative spliced isoforms in skeletal muscle during exercise. In the present study, we validated two AXL alternative splicing transcripts (named as AXLa for long form and AXLb for short form) in equine skeletal muscle to gain insight(s) into the role of each alternative transcript during exercise. Methods: We validated two isoforms of AXL transcripts in horse tissues by reverse transcriptase polymerase chain reaction (RT-PCR), and then cloned the transcripts to confirm the alternative locus and its sequences. Additionally, we examined the expression patterns of AXLa and AXLb transcripts in horse tissues by quantitative RT-PCR (qRT-PCR). Results: Both of AXLa and AXLb transcripts were expressed in horse skeletal muscle and the expression levels were significantly increased after exercise. The sequencing analysis showed that there was an alternative splicing event at exon 11 between AXLa and AXLb transcripts. 3-dimentional (3D) prediction of the alternative protein structures revealed that the structural distance of the connective region between fibronectin type 3 (FN3) and immunoglobin (Ig) domain was different between two alternative isoforms. Conclusion: It is assumed that the expression patterns of AXLa and AXLb transcripts would be involved in regulation of exercise-induced stress in horse muscle possibly through an $NF-{\kappa}B$ signaling pathway. Further study is necessary to uncover biological function(s) and significance of the alternative splicing isoforms in race horse skeletal muscle.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2015년도 제49회 하계 정기학술대회 초록집
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• pp.188.1-188.1
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• 2015

For present investigation Fe/MgO/Fe/Co multilayer stack is grown on Si substrate using e-beam evaporation in ultrahigh vacuum. This stack is irradiated perpendicularly by 120 MeV $Ag^{8+}$ at different fluences ranging from $1{\times}10^{11}$ to $1{\times}10^{13}ions/cm^2$ in high vacuum using 15UD Pelletron Accelerator at Inter University Accelerator Centre, New Delhi. Magnetic measurements carried out on pre and post irradiated stacks show significant changes in the shape of perpendicular hysteresis which is relevant with previous observation of re-orientation of magnetic moment along the direction of ion trajectory. However increase in plane squareness may be due to the modification of interface structure of stacks. X-ray reflectivity measurements show onset of interface roughness and interface mixing. X-ray diffraction measurements carried out using synchrotron radiation shows amorphous nature of MgO and Co layer in the stack. Peak corresponding body centered Fe [JCPDS-06-0696] is observed in X-ray diffraction pattern of pre and post irradiated stacks. Peak broadening shows granular nature of Fe layer. Estimated crystallite size is $22{\pm}1nm$ for pre-irradiated stack. Crystallite size first increases with irradiation then decreases. Structural quality of these stacks was further studied using transmission electron microscopic measurements. Thickness from these measurements are 54, 36, 23, 58 and 3 nm respectively for MgO, Fe, MgO, Fe+Co and Au layers in the stack. These measurements envisage poor crystallinity of different layers. Interfaces are not clear which indicate mixing at interface. With increase fluence mixing and diffusion was increased in the stack. X-ray absorption spectroscopic measurements carried out on these stacks show changes of Fe valence state after irradiation along with change of O(2p)-metal (3d) hybridized state. Valence state change predicts oxide formation at interface which causes enhanced in-plane magnetization.

• 에너지공학
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• 제21권4호
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• pp.339-345
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• 2012

최근 안정성 및 경제성 측면에서 완전방호식 LNG 저장탱크(full-containment LNG storage tank)의 대안으로 검토되고 있는 멤브레인 LNG 저장탱크(membrane LNG storage tank)에 대해서 정량적 위험성 평가 방법(QRA; Quantitative Risk Analysis)과 유한요소해석법(FEM; Finite Element Method)을 통하여 안전성 평가를 수행하였다. 본 논문에서는 유한요소해석법(FEM)을 통한 구조안전성 평가에서 140,000 $m^3$ 저장용량을 갖는 LNG 저장탱크의 두 가지 모델은 저장탱크 시스템에 대한 강도 안전성과 누출 안전성 측면에서 해석한 결과에 의하면 모두 안전한 것으로 평가되었다. 또한, 고장수목분석(FTA; Fault Tree Analysis)을 통하여 멤브레인 LNG 저장탱크에 안전성을 강화하기 위해 설계 초기모델에 안전장치로서 멤브레인 바닥부의 충격흡수장치(impact absorber structure), 1차 멤브레인 저장 파손 시 콘크리트 외부탱크(outer tank) 코너부(corner part)의 열충격(thermal stress)을 감소시킬 수 있는 열보호장지(secondary barrier) 및 펌프 낙하 시 안전장치로서 펌프캐쳐(pump catcher)를 보완하고 평가하였다. 결론적으로 개선된 멤브레인 LNG 저장탱크는 안전성 측면에서 완전방호식 LNG 저장탱크와 대등하다는 결론을 도출할 수 있었다.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2010년도 추계 학술발표회 3차
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• pp.72-77
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• 2010

The Incheon Bridge, which was opened to the traffic in October 2009, is an 18.4 km long sea-crossing bridge connecting the Incheon International Airport with the expressway networks around the Seoul metropolitan area by way of Songdo District of Incheon City. This bridge is an integration of several special featured bridges and the major part of the bridge consists of cable-stayed spans. This marine cable-stayed bridge has a main span of 800 m wide to cross the vessel navigation channel in and out of the Incheon Port. In waterways where ship collision is anticipated, bridges shall be designed to resist ship impact forces, and/or, adequately protected by ship impact protection (SIP) systems. For the Incheon Bridge, large diameter circular dolphins as SIP were made at 44 locations of the both side of the main span around the piers of the cable-stayed bridge span. This world's largest dolphin-type SIP system protects the bridge against the collision with 100,000 DWT tanker navigating the channel with speed of 10 knots. Diameter of the dolphin is up to 25 m. Vessel collision risk was assessed by probability based analysis with AASHTO Method-II. The annual frequency of bridge collapse through the risk analysis for 71,370 cases of the impact scenario was less than $0.5{\times}10^{-4}$ and satisfies design requirements. The dolphin is the circular sheet pile structure filled with crushed rock and closed at the top with a robust concrete cap. The structural design was performed with numerical analyses of which constitutional model was verified by the physical model experiment using the geo-centrifugal testing equipment. 3D non-linear finite element models were used to analyze the structural response and energy-dissipating capability of dolphins which were deeply embedded in the seabed. The dolphin structure secures external stability and internal stability for ordinary loads such as wave and current pressure. Considering failure mechanism, stability assessment was performed for the strength limit state and service limit state of the dolphins. The friction angle of the crushed stone as a filling material was reduced to $38^{\circ}$ considering the possibility of contracting behavior as the impact.

• Structural Engineering and Mechanics
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• 제57권1호
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• pp.1-20
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• 2016

On the basis of the geological conditions of high and steep mountainous slope on which an exit portal of an express railway tunnel with a bridge-tunnel combination is to be built, the composite structure of the exit portal with a bridge abutment of the bridge-tunnel combination is presented and the stability of the slope on which the express railway portal is to be built is analyzed using three dimensional (3D) numerical simulation in the paper. Comparison of the practicability for the reinforcement of slope with in-situ bored piles and diaphragm walls are performed so as to enhance the stability of the high and steep slope. The safety factor of the slope due to rockmass excavation both inside the exit portal and beneath the bridge abutment of the bridge-tunnel combination has been also derived using strength reduction technique. The obtained results show that post tunnel portal is a preferred structure to fit high and steep slope, and the surrounding rock around the exit portal of the tunnel on the high and steep mountainous slope remains stable when rockmass is excavated both from the inside of the exit portal and underneath the bridge abutment after the slope is reinforced with both bored piles and diaphragm walls. The stability of the high and steep slope is principally dominated by the shear stress state of the rockmass at the toe of the slope; the procedure of excavating rockmass in the foundation pit of the bridge abutment does not obviously affect the slope stability. In-situ bored piles are more effective in controlling the deformation of the abutment foundation pit in comparison with diaphragm walls and are used as a preferred retaining structure to uphold the stability of slope in respect of the lesser time, easier procedure and lower cost in the construction of the exit portal with bridge-tunnel combination on the high and steep mountainous slope. The results obtained from the numerical analysis in the paper can be used to guide the structural design and construction of express railway tunnel portal with bridge-tunnel combination on high and abrupt mountainous slope under similar situations.

• 한국전산구조공학회논문집
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• 제32권1호
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• pp.37-44
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• 2019

결합 기반 페리다이나믹 모델은 간단한 재료 모델을 통해 취성 재료의 다양한 동적 파괴 특성을 확인할 수 있었지만, 다양한 재료 구성 모델을 표현하는데 많은 한계점이 나타났다. 특히, 절점 간 결합이 서로 독립적으로 작용하여 포아송 비가 고정되고 전단 변형이 표현되는 않는 문제점이 있다. 상태 기반 페리다이나믹 모델은 보다 일반화되고 엄밀한 재료 모델링이 가능하며, 모든 결합의 변형 정보를 통해 각 절점의 거동이 계산되기 때문에 결합 기반 모델에서 표현하지 못한 전단 변형까지도 표현 가능하다. 본 연구에서는 상태 기반 페리다이나믹 모델을 통해 재료 모델을 구성하고, 소성 흐름 법칙으로부터 재료의 완전 소성 거동을 표현할 수 있도록 간단한 재료 모델을 구성한다. 평판 수치 예제를 통해 구성된 완전 소성 재료 모델을 검증하고 응력 변형 곡선을 확인한다. 또한 비국부 접촉 모델링을 통해 서로 다른 두 물체가 충돌하는 현상을 모사하여, 화강암반 모델의 고속 충돌 파괴 해석을 수행하고 결과분석 및 실험현상과 비교한다.

• 한국정보통신학회논문지
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• 제16권1호
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• pp.176-182
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• 2012

최근에는 응용과학 분야의 교육 및 연구에 실제 실험이 아닌 슈퍼컴퓨터 및 고성능 네트워크 기반의 사이버 인프라에서 과학적 가정에 의해 복잡한 공학문제를 수치적 모델링과 컴퓨터 시뮬레이션을 통해 해결하는 계산과학을 이용하는 기법들의 필요성이 증대되고 있다. 본 논문에서는 컴퓨팅 시뮬레이션 기법을 활용한 실험 체험형 교육의 일환으로, 이공계 교수, 학생, 연구자, 산업체 인력 등이 사이버 인프라스트럭처 기반으로 시뮬레이션 SW를 활용한 교육 및 융합연구를 지원하는 EDISON 플랫폼을 제시한다. EDISON 플랫폼은 사용자들에게 보다 쉽고, 편하고, 효과적인 서비스 제공을 위해 3계층(EDISON 응용 프레임워크, EDISON 미들웨어, EDISON 인프라 자원)으로 구성되고 5개 분야(열유체, 화학, 물리, 구조동역학, 전산설계) 문제해결 환경을 위한 교육 연구용 웹 포털 서비스를 제공한다.

• 대한기계학회논문집A
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• 제36권3호
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• pp.347-353
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• 2012

최근 휴대폰은 스마트폰의 출연으로 다기능화가 요구되고 있으며, 각 보드의 전기적 신호를 연결시키는 커넥터는 필수 핵심 부품이 되었다. 커넥터는 많은 양의 전기신호를 처리하기 때문에 소형화, 협피치화가 필요하다. 하지만, 커넥터의 소형화 및 협피치화는 구조적 안전성을 저하시키며, 외부하중에 의한 접촉불량을 발생시킨다. 따라서 본 논문에서는 초소형 협피치 FPC 커넥터를 개발하기 위해 벤치마킹을 통한 초기설계안을 도출하였으며, 터미널 두께 0.2mm, 개수 50 개를 기준으로 하였다. 체결성능을 평가하기 위해 수치해석 모델을 구성하였으며, 다구찌 방법을 이용하여 형상 최적화를 수행하였다. 또한, 터미널의 한계수명을 예측하기 위해 피로해석을 수행하였으며, 체결 성능이 향상된 최종형상을 도출하였다.