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Control of Hydrolytic Degradation of Polylactide Mixtures Using Optical Isomers (광학이성질체를 이용한 폴리락타이드 혼합물의 가수분해성 조절)

  • Lee, Won-Ki
    • Polymer(Korea)
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    • v.36 no.3
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    • pp.309-314
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    • 2012
  • To control degradation rate of biodegradable poly(lactide)s (PLA), the stereochemical PLAs with different ratios of $d$-lactide and $l$-lactide units were synthesized by the ring open polymerization and a degradation behavior was measured by a Langmuir film balance. Degradation rates of mixture monolayers on alkaline subphase were investigated as a function of optical purity of mixture component, 100, 99, 97 and 95%. As increasing their optical purity, melting temperatures of mixtures from stereocomplexation increased. The degradation rate of mixture monolayer with 100% optical purity was much slower than that of each homopolymer one and the others showed 2 step degradation behaviors. In the first step, the degradation which is faster than that of each homopolymer occurs in the uncomplexed region, and secondly, the degradation occurred in the complexed region which showed similar degradation rate to that of 100% optical purity. These results indicate that the alkaline degradation of stereochemical PLAs could be controlled by stereochemistry and stereocomplexation between enantiomer PLAs.

Effect of Merchanized and Intergrated Working System of Job's Tears Cultivation on the Time and Expenditure (율무 재배의 기계화 일관 작업체계가 시간 및 경비에 미치는 영향)

  • 강치훈;김기중;유창재;김두환
    • Korean Journal of Plant Resources
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    • v.14 no.1
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    • pp.71-76
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    • 2001
  • This experiment was conducted to investigate the effect of the mechanized and intergrated working system on the reduction of time and expenditure for job's tears (Coix lachryma-jobi L.) cultivation. Emergence rate of working system was 50% at the merchanized and 62% at the conventional. Total working time was 230 minutes/10a at the merchanized and 2,273 minutes/10a at the conventional. Expenditure was 111,061 won/10a at the merchanized and 189,781 won/10a at the conventional. Date of emergence, budding, and flowering were the same for two systems. Growth characteristics were similiar in two systems, corn borer rate was 3.0% at the merchanized and 13.3% at the conventional. Grain yield components was higher at the merchanized than at the conventional. Thereby, grain yield was 351 kg/10a at the merchanized and 309 kg/10a at the conventional.

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Removal of Toxicity from Kraft Pulp Mill Effluents by Activated Sludge Process (활성슬러지 공정에 의한 Kraft 펄프 폐수의 독성 제거)

  • Kim, Yeong-Kwan
    • Journal of Korean Society of Water and Wastewater
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    • v.8 no.3
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    • pp.9-18
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    • 1994
  • Activated sludge pilot plant testing was conducted to determine the ability of a well-designed activated sludge treatment system to remove chromic toxicity from the bleached kraft pulp mill effluent. Removals of conventional(BOD and SS) and nonconventional(resin and fatty acids, color, AOX) pollutants were estimated. The pilot plant was operated at steady state for about 10 weeks at an F/M of 0.28 and a sludge age of 8.4 days. The average MLSS concentration was 4,309mg/l, of which volatile fraction was 57%. During the operation period, the BOD removal reaction rate(k) was determined to be 8.2/day at $30^{\circ}C$. The BOD removal was 84 percent, which was 3 to 6 percent lower than expected for full-scale treatment. The chronic toxicity of the activated sludge effluent was tested by employing both Dinnel and the BML protocols. It was found that the pilot plant could achieve in excess of 90 percent reduction in chronic echinoderm toxicity. The data show slight reduction of color and AOX across the activated sludge system. The pilot system, however, demonstrated on excellent removal of resin and fatty acids.

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Therapeutic monitoring of vancomycin according to initial dosing regimen in pediatric patients

  • Kim, Dae-Il;Im, Mi-Sun;Choi, Jin-Hyoung;Lee, Jin-A;Choi, Eun Hwa;Lee, Hoan-Jong
    • Clinical and Experimental Pediatrics
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    • v.53 no.12
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    • pp.1000-1005
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    • 2010
  • Purpose: This study aimed to determine the optimal initial vancomycin dose to achieve appropriate trough levels in pediatric patients. Methods: We analyzed clinical data for 309 children treated with intravenous vancomycin between 2004 and 2009 at 2 different hospitals in South Korea. The patients were 1-16 years old and exhibited normal renal function. Patient data, including reason for treatment and initial dosing regimen, were reviewed. Two subgroups were identified and compared according to initial vancomycin dose: 40 (35-45) mg/kg/day and 60 (55-65) mg/kg/day. Trough levels were obtained at steady state after at least 4 doses of vancomycin. Results: Patients who received vancomycin had post-operation or wound-related infections (37.2%), localized infection (12.9%), catheter-related infections (9.4%), meningitis (8.7%), or endocarditis (6.8%). Pathogens were confirmed in 79 cases: 28 cases of methicillin-resistant $Staphylococcus$ $epidermidis$ (35.4%) and 25 of methicillin-resistant $Staphylococcus$ $aureus$ (31.6%). Out of the 309 patients, 201 (65%) received vancomycin at 40 mg/kg/day and 108 (35%) at 60 mg/kg/day. Average trough concentrations were significantly different between the groups ($P$<0.001). Trough levels over 10 mg/L were less likely to be achieved in the 40 mg/kg/day group (14%) than in the 60 mg/kg/day group (49%) ($P$<0.001). There were no differences in renal function deterioration between the groups. Conclusion: A common vancomycin dosing regimen, 40 mg/kg/day, was not high enough to achieve trough levels of over 10 mg/L in pediatric patients. Careful drug monitoring must be performed, and increasing initial dose of vancomycin should be considered in pediatric patients.

Cultural Condition of Enterobacter agglomerans U-1 for Polysaccharide Production (Enterobacter agglomerans U-1의 다당류 생산을 위한 배양조건)

  • Yoo, Jin-Young;Koo, Young-Jo;Shin, Dong-Hwa;Chung, Dong-Hyo
    • Applied Biological Chemistry
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    • v.32 no.3
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    • pp.309-314
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    • 1989
  • The cultural condition of Enterobacter agglomerans U-1, a polysaccharide producing soil bacterium, was examined. The optimal medium composition was that contains the following components per liter of distilled water; $sucrose(23.75\;g/L),\;peptone(2.06\;g/L),\;yeast\;extract(0.5\;g/L),\;KH_2PO_4(1.0\;g/L)$ and $MgSO_4{\cdot}7H_2O(1.0 g/L)$. The optimum temperature for polysaccharide production was $30^{\circ}C$, where 8.5 g/L of polysaccharide was produced. The apparent viscosity of fermentation broth after 3 days was 240 mPa.s. at $70sec^{-1}$. The product yield and specific productivity were 36% and 142.07 mg/g/h.

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Study on Heat-Loss-Induced Self-Excitation in Laminar Lifted Jet Flames (층류제트 부상화염에서 열손실에 의한 자기진동에 관한 연구)

  • Yoon, Sung-Hwan;Park, Jeong;Kwon, Oh-Boong;Kim, Jeong-Soo;Bae, Dae-Seok;Yun, Jin-Han;Keel, San-In
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.35 no.3
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    • pp.309-319
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    • 2011
  • We experimentally investigated lifted propane jet flames diluted with nitrogen to obtain flame-stability maps based on heat-loss-induced self-excitation. We found that heat-loss-induced self-excitations are caused by conductive heat loss from premixed flame branches to trailing diffusion flames as well as soot radiation. The conductive-heat-loss-induced self-excitation at frequencies less than 0.1 Hz is explained well by a suggested mechanism, whereas the oscillation of the soot region induces a self-excitation of lift-off height of the order of 0.1 Hz. The suggested mechanism is also verified from additive experiments in a room at constant temperature and humidity. The heat-loss-induced self-excitation is explained by the Strouhal numbers as a function of the relevant parameters.

Gonadal Development and Sex Steroid Hormone Levels of the Yellowfin Goby Acahthogobius flavimanus (문절망둑(Acanthogobius flavimanus)의 생식소 발달과 혈중 성 스테로이드호르몬 농도 변화)

  • PARK Myoung Hee;HWANG In Joon;KIM Dae Jung;LEE Young Don;KIM Hyung Bae;BAEK Hea Ja
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.38 no.5
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    • pp.309-315
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    • 2005
  • Changes of sex steroid hormones in the plasma of yellowfin goby, Acanthogobius flavimanus were investigated in relation to the gonadosomatic index (GSI), the hepatosomatic index (HSI) and gonadal development. The GSI in females rose rapidly in November and remained high from December to May $(7.26\pm0.89­6.62\pm0.02)$. The Male's GSI also increased gradually from November and was highest in May $(0.16\pm0.08)$. The HSI in both sexes was in reverse correlation with the GSI, and the HSI was low during the spawning season (February-May). In females, the $estradiol-17{\beta}\;(E_2)$ level increased during vitellogenesis (November and December) and reached its maximum $(8.13\pm2.87 ng/mL)$ at the maturing period, in January. $17{\alpha},\;20{\beta}$-dihydroxy-4-pregnen-3-one$(17{\alpha}20{\beta}OHP)$ gradually increased from October $(0.063{\pm}0.02ng/mL)$ to March $(0.16{\pm}0.02ng/mL)$ and increased rapidly in May. The level of testosterone (T) showed a similar tendency of $E_2$. In males, T increased gradually during spermatogenesis from September to December $(0.14{\pm}0.06­0.26{\pm}0.10ng/mL)$ and peaked in January $(0.36{\pm}0.29 ng/mL)$ when the spermatozoa filled the testis. 11-KT also rose markedly in January and then decreased. On the other hand, $17{\alpha}29{\beta}OHP$ in males did not show any clear tendencies.

Life History of Porphyra seriata Kjellman (Bangiales, Rhodophyta) from Korea in Laboratory Culture

  • Kim, Nam-Gil;Notoya, Masahiro
    • ALGAE
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    • v.19 no.4
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    • pp.303-309
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    • 2004
  • The laboratory culture study of Porphyra seriata Kjellman from Korea was conducted at different conditions of temperatures (5, 10, 15, 20, 25 and 30${^{\circ}C}$), photon flux densities (10, 20, 40 and 80 $\mu$mol $^{-2}s^{-1}$) and photoperiods (14L: 10D and 10L:14D). Conchocelis filaments grew fast at 15-20${^{\circ}C}$ and 20-80 $\mu$mol $^{-2}s^{-1}$ under both photoperiods. Concho sporangial branches were produced at 5-25${^{\circ}C}$, and abundant when the conchocelis filaments were cultured at higher temperatures of 20-25${^{\circ}C}$ under both photoperiods. Foliose thalli grew well at 15-20${^{\circ}C}$ under 10L:14D and at 20${^{\circ}C}$ under 14L:10D. At 30${^{\circ}C}$, the foliose thallus failed to survive. No archespores were observed at any culture conditions. Spermatangia and zygotosporangia were formed in squarish patches at the upper marginal portion of mature thalli. Anatomical examination revealed that the mature spermatangia were 64 (a/4, b/2, c/8) and 128 (a/4, b/4, c/8), and that of zygotosporangium was 16 (a/2, b/2, c/4) according to the Hus' formula.

Optimal Operational Characteristics of Wastewater Treatment Using Hydrocyclone in a Sequencing Batch Reactor Process (연속회분식반응기 공정의 하이드로사이클론 도입 하수처리 최적 운전특성)

  • Kwon, Gyutae;Kim, Hyun-Gu;Ahn, Dae-Hee
    • Journal of Environmental Science International
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    • v.31 no.4
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    • pp.295-309
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    • 2022
  • The purpose of this study was to evaluate the operational characteristics of wastewater treatment using Sequencing Batch Reactor (SBR) with Aerobic Granular Sludge (AGS) separator in the pilot plant. Pilot plant experiments were conducted using SBR with AGS separator and pollution removal efficiencies were evaluated based on the operational condition and surface properties of AGS. The results of the operation on water quality of the effluent showed that the average concentration of total organic carbon, suspended solids, nitrogen, and phosphorus was 6.89 mg/L, 7.33 mg/L, 7.33 mg/L, and 0.2 mg/L, respectively. All these concentrations complied the effluent standard in Korea. The concentration of mixed liquor suspended solid (MLSS) fluctuated, but the AGS/MLSS ratio was constant at 86.5±1.3%. Although the AGS/MLSS ratio was constant, sludge volume index improved. These results suggested that the particle discharged fine sludge and increased the AGS praticle size in the AGS. Optical microscopy revealed the presence of dense AGS at the end of the operation, and particles of > 0.6 mm were found. Compared to those of belt-type AGS separator, the required area and power consumption of the hydrocyclone-type AGS separator were reduced by 27.5% and 83.8%, respectively.

To study of optimal subgroup size for estimating variance on autocorrelated small samples (소표본 자기상관 자료의 분산 추정을 위한 최적 부분군 크기에 대한 연구)

  • Lee, Jong-Seon;Lee, Jae-Jun;Bae, Soon-Hee
    • Proceedings of the Korean Society for Quality Management Conference
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    • 2007.04a
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    • pp.302-309
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    • 2007
  • To conduct statistical process control needs the assumption that the process data are independent. However, most of chemical processes, like a semi-conduct processes do not satisfy the assumption because of autocorrelation. It causes abnormal out of control signal in the process control and misleading process capability. In this study, we introduce that Shore's method to solve the problem and to find the optimal subgroup size to estimate variance for AR(l) model. Especially, we focus on finding an actual subgroup size for small samples using simulation. It may be very useful for statistical process control to analyze process capability and to make a Shewhart chart properly.

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