• Title/Summary/Keyword: 3 D.O.F. stage

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Development of Three D.O.F. Alignment Stage for Vaccume Environment (진공용 3 자유도 얼라인먼트 스테이지 개발)

  • 박희재;박종호;한상진
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2000.11a
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    • pp.551-554
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    • 2000
  • Alignment system is a system to locate an object to it's accurate position in multi-d.o.f space. According to process of application, it is need to align an object in 3 or 6 d.o.f. space. And alignment system is used in various environments. Especially in PDP application, alignment process is carried out in vaccume environment. In this paper, we developed 3 d.o.f. alignment system for vaccume environment, performed kinematic analysis and improved it's positional accuracy.

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In Vitro Evaluation of Two Novel Antimalarial Derivatives of SKM13: SKM13-MeO and SKM13-F

  • Thuy-Tien Thi Trinh;Young-ah Kim;Hyelee Hong;Linh Thi Thuy Le;Hayoung Jang;Soon-Ai Kim;Hyun Park;Hak Sung Kim;Seon-Ju Yeo
    • Parasites, Hosts and Diseases
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    • v.60 no.6
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    • pp.401-407
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    • 2022
  • Antimalarial drugs play an important role in the control and treatment of malaria, a deadly disease caused by the protozoan parasite Plasmodium spp. The development of novel antimalarial agents effective against drug-resistant malarial parasites is urgently needed. The novel derivatives, SKM13-MeO and SKM13-F, were designed based on an SKM13 template by replacing the phenyl group with electron-donating (-OMe) or electron-withdrawing groups (-F), respectively, to reverse the electron density. A colorimetric assay was used to quantify cytotoxicity, and in vitro inhibition assays were performed on 3 different blood stages (ring, trophozoite, and schizonts) of P. falciparum 3D7 and the ring/mixed stage of D6 strain after synchronization. The in vitro cytotoxicity analysis showed that 2 new SKM13 derivatives reduced the cytotoxicity of the SKM13 template. SKM13 maintained the IC50 at the ring and trophozoite stages but not at the schizont stage. The IC50 values for both the trophozoite stage of P. falciparum 3D7 and ring/mixed stages of D6 demonstrated that 2 SKM13 derivatives had decreased antimalarial efficacy, particularly for the SKM13-F derivative. SKM13 may be comparably effective in ring and trophozoite, and electron-donating groups (-OMe) may be better maintain the antimalarial activity than electron-withdrawing groups (-F) in SKM13 modification.

Six D.O.F Ultra Fine Stage using Electromagnetic Force Control (전자기력 제어를 이용한 6 자유도 초정밀 스테이지)

  • 정광석;백윤수
    • Journal of the Korean Society for Precision Engineering
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    • v.17 no.3
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    • pp.158-164
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    • 2000
  • In recent year, desire and request fer micro automation are growing rapidly covering the whole range of the industry. This has been caused mainly by request of more accurate manufacturing process due to a higher density of integrated circuits in semiconductor industry. This paper presents a six d.o.f fine motion stage using magnetic levitation technique, which is one of actuating techniques that have the potential for achieving such a micro motion. There is no limit in motion resolution theoretically that the magnetically levitated part over a fixed stator can realize. In addition, it Is possible to manipulate the position and the force of the moving part at the same time. Then, the magnetic levitation technique is chosen into the actuating method. However, we discuss issues of design, kinematics, dynamics, and control of the proposed system. And a few experimental results fur step input are given.

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Study on recovery of $Na_{2}SiF_6$ and acetic acid from waste acid produced during semiconductor wafer process (반도체 웨이퍼 제조공정(製造工程) 중 발생불산(發生廢酸)으로부터 $Na_{2}SiF_6$ 및 초산의 회수(回收)에 관한 연구(硏究))

  • Kim, Hyun-Sang;Kim, Ju-Yup;Lee, Hyang-Sook;Shin, Chang-Hoon;Kim, Jun-Young;Bae, Woo-Keun;Ahn, Jong-Kwan
    • Resources Recycling
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    • v.17 no.5
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    • pp.3-10
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    • 2008
  • We researched recycle of mixed waste acids including HF, $CH_{3}COOH$, $HNO_3$ produced during semiconductor wafer process. At first, we recovered HF in form of $Na_{2}SiF_6$ by precipitation using $NaNO_3$ and $Na_{2}SiO_3$. Concentration of HF was made down from 110 g/L, initial concectration, to 0.5 g/L and Recovery rate of HF was 99.5%. After recovery of HF, concentration of $HNO_3$ and $CH_{3}COOH$ is 498 g/L, 265 g/L respectively. From that mixed acid, we recovered $CH_{3}COOH$ using 2 stages of fractional distillation. In first stage, $CH_{3}COOH$ was distilled for separation from $HNO_3$. And in second stage, we recoverd refined $CH_{3}COOH$ by using fractional distillation for removing a little amount of $HNO_3$ in $CH_{3}COOH$ vapor. The concentration of recovered $CH_{3}COOH$ in second stage is 20% and finally recovery rate of $CH_{3}COOH$ is about 87.5%.

Development of Three D.O.F Alignment Stage for Vacuum Environment (진공용 3자유도 얼라인먼트 스테이지 개발)

  • Han, Sang-Jin;Park, Jong-Ho;Park, Hui-Jae
    • Journal of the Korean Society for Precision Engineering
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    • v.18 no.11
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    • pp.138-147
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    • 2001
  • Alignment systems are frequently used under various semiconductor manufacturing environment. Particularly in PDP(Plasma Display Panel) manufacturing process, the alignment system is applied to the combining and sealing processes of the upper and lower glass panels of PDP, where these processes are performed in the vacuum chamber of high vacuum and high temperature. In this paper, the XYΘ-alignment stage is developed to align PDP panels. Because of high vacuum and high temperature environment, the alignment chamber has been designed to isolate the inner part of the alignment chamber from the outer environment of high vacuum and high temperature, in which every part of the alignment stage is inserted. As it is difficult to attach feedback sensors to the alignment stage in the alignment chamber, the alignment stage is implemented with the open loop algorithm, where the parallel link structure has been designed using step-motors and ball-screws for structural simplicity. The kinematic analysis is performed to drive the parallel link structure, based on the experiments of actuation-compensation of the alignment stage. For the error compensation, the hyperpatch model has been used to model the errors. From the experiments, the positional accuracy of the alignment stage can be improved significantly.

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Inheritance of Resistance to Bacterial Leaf Blight Caused by Xanthomonas oryzae (Uyeda at Isheyama) Dowson in Rice (벼 흰빛잎마름병 저항성유전에 관한 연구)

  • Sohn J.K.;Kim M.H.
    • Korean journal of applied entomology
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    • v.19 no.3 s.44
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    • pp.156-162
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    • 1980
  • The inheritance and varietal differences of resistance to bacterial leaf blight caused by Xanthomonas oryzae in rice were studied. Among eighteen cultivars used, 'IR2061-465-1-5-5', 'IR2061-552-6-9', 'IR 1561-228-9-3', ana 'Milyang42, were found to have a high level of resistance to the three isolates of X. oryzae at maximum tillering and flowering stage. Varietal differences in lesion development of the cultivars belonging to the same varietal group were clearly recognized. For the genetic study on bacterial leaf blight resistance, two rice breeding lines 'IR2061-465-1-5-5', 'IR1561-228-3-3' were crossed with susceptible cultivar 'Milyang 23'. The $F_1,F_2,\;and\;F_3$ progenies were evaluated at flowering stage using the bacterial isolate 'JN 7853'(II). Average lesion length of the $F_1$ plants of the crosses showed longer than that of resistant parents, and the frequency distribution of lesion length in the $F_2\;and\;F_3$ populations showed continuous variation.

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A Study on Substrate Stage Temperature (기판스테이지 온도에 관한 연구)

  • Kim, Sun-Ki;Lee, Woo-Young;Kang, Heung-Suk
    • Journal of the Semiconductor & Display Technology
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    • v.5 no.4 s.17
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    • pp.35-40
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    • 2006
  • This paper shows that the effect of exposing on the top area and a solution which using a water circulation system. Semiconductor substrate stage is made from Aluminum and is repeated the sequence of exposing (150), turning OFF shutter, taking 30 sec. interval at the top area of stage. So the temperature of substrate temperature rises continuously. On this, we made a waterway at the inner part of the substrate stage and operated a water circulation system. We measured the temperature of a substrate stage surface with a thermocouple attached to the substrate stage. To analyze the top area's temperature, we used Analysis Program ANSYS for analysis and 3D CAD program Solid-Works for modeling.

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Morningness-Eveningness Affects the Depressive Mood and Day Time Sleepiness of Obstructive Sleep Apnea Syndrome Patient (폐쇄성 수면무호흡증 환자에서 일주기 리듬 특성에 따른 주간 졸음과 우울감의 차이)

  • Kim, Seong Ho;Joo, Eun-Jeong;Lee, Kyu Young;Koo, Young Jin;Kim, Eui-Joong
    • Sleep Medicine and Psychophysiology
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    • v.19 no.2
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    • pp.77-83
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    • 2012
  • Objectives: Recent studies have reported a correlation between obstructive sleep apnea syndrome (OSA) and depression. In attempt to verify the suggestion that eveningness is related to depression, we examined the effect of morningness-eveningness on their depressive mood in patinets with OSA. Methods: The examination was based on the medical records and polysomnography reports of 211 OSA patients. Information was gathered from the patients who filled out the H$\ddot{o}$rne and Ostberg questionnaire (HOQ), profile of mood states-Korean version (K-POMS), and Epworth sleepiness scale (ESS). We compared mean values of K-POMS total, subscales of K-POMS, ESS, and OSA severity variables among the 3 morningness-eveningness groups (morningness, eveningness, and neither groups). Partial correlation analysis was performed between variables and ANCOVA was performed among the 3 groups after adjustment with age and weight. Results: There were significant negative correlations between HOQ and the followings : K-POMS total, POMS-T (tension-anxiety), POMS-D (depression-dejection), POMS-A (anger-hostility), POMS-F (fatigue-inertia), POMS-C (confusion-bewilderment), spontaneous arousal index, average O2 saturation. There were significant positive correlations between HOQ and the followings : POMS-V (vigor-activity), apnea-hypopnea index, respiratory arousal index, snore time. There were significant negative correlations between POMS-D and the followings : HOQ, POMS-V, stage 1 sleep (%), AHI, TAI (total arousal index), oxygen desaturation index, respiratory arousal index, neck circumference, average O2 desaturation, snore time (%). There were significant positive correlations between POMS-D and K-POMS total, POMS-T, POMS-A, POMS-F, POMS-C, sleep latency, stage 2 sleep (%), heart rate, spontaneous arousal index. There were significant differences in K-POMS total, POMS-T, POMS-D, POMS-F, POMS-C, spontaneous arousal index among the three HOQ groups in ANCOVA. Conclusion: The depressive correlates of OSA patients might be affected, not by excessive daytime sleepiness or OSA severity indexes, but by eveningness circadian characteristics. It would be important to take into account the morningness-eveningness tendency when we manage the depressive mood of OSA patients.

Occurrence and chemistry of pyrochlore and baddeleyite in the Sokli carbonatite complex, Kola Peninsula, Arctic

  • Lee, Mi-Jung;C. Terry Williams;Lee, Jong-Ik;Kim, Yeadong
    • Proceedings of the Mineralogical Society of Korea Conference
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    • 2003.05a
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    • pp.67-67
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    • 2003
  • The chemical compositions and textural relationships of the Nb-Zr oxide minerals including pyrochlore [ideally (Ca,Na)$_2$Nb$_2$O$\sub$6/(OH,F), with up to 24% UO$_2$ and 16% Ta$_2$O$\sub$5/] and baddeleyite [ideally ZrO$_2$, with up to 6% Nb$_2$O$\sub$5/] in the Sokli carbonatite complex, Kola Peninsula, Arctic are described. These two minerals in carbonatites are the major hosts for the HFSEs such as U, Th, Ta, Nb, Zr and Hf and thus are interest both economically and petrologically. The Sokli carbonatite complex (360-370 Ma) in Northern Finland, which forms a part of the Paleozoic Kola Alkaline Province (KAP), is mainly composed of multi-stages of carbonatite and phoscorite associations (P1-C1 P2-C2, P3-C3, D4 and D5) surrounded by altered ultramafic rocks (olivinite and pyroxenite) and cut by numerous small dikes of ultramafic lamprophyre. The Sokli complex contains the highest concentration in niobium and probably in tantalum, which are economically very important to modern steel technology, among the ultramafic-alkaline complexes of the KAP. Pyrochlore and baddeleyite mostly concentrate in the phoscorites. Pyrochlores in the Sokli complex are generally rounded octahedra and cubes in shape, red brown to grey yellow in color, and 0.2 to 5 mm in size. They are found in all calcite carbonatites, phoscorites and dolomite carbonatites, except P1-C1 rocks. These pyrochlores display remarkable zonations which depend on host rock compositions, and have significant compositional variations with evolution of the Sokli complex. The common variation scheme is that (1) early pyrochlore is highly enriched in U and Ta; (2) these elements decrease abruptly in the intermediate stage, while Th and Ce increase, and (3) late stage pyrochlore is low in U, Ta, Th, and Ce, and correspondingly high in Nb. Baddeleyites in the Sokli complex occur in the early P1-C1 and P2-C2 rocks and rarely in P3. They crystallized earlier than pyrochlores, and occasionally show post-magmatic corrosion and replacement. The FeO and TiO$_2$ contents of baddeleyites are much lower than those of the other terrestrial and lunar baddeleyites, whereas Nb$_2$O$\sub$5/ and Ta$_2$O$\sub$5/ contents are the highest among the reported compositions. Ta/Nb and Zr/Nb ratios of pyrochlores and baddeleyites decrease towards later stage facies, which is in accordance with the whole rock compositions. The variation of Ta/Nb and Zr/Nb ratios of pyrochlores and baddeleyites is considered to be a good indicator to trace an evolution of the carbonatite complexes.

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A Vibration Mode Analysis of Resilient Mounting System and Foundation Structure of Acoustic Enclosure using Finite Element Method (유한요소법을 이용한 음향차폐장치용 탄성마운트 시스템 및 받침대의 진동모드 해석)

  • 정우진;배수룡;함일배
    • Journal of KSNVE
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    • v.9 no.3
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    • pp.493-501
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    • 1999
  • The vibration modes of resilient mounting system and foundation structure which support diesel engine/generator set and acoustic enclosure walls play an important role in the vibration transmission process. So, it is necessary to perform vibration mode analysis of resilient mounting system and foundation structure. For some reasons, if the vibration modal analysis of resilient mounting system and foundation structure of acoustic enclosure could be simultaneously done by finite element method, it would be very efficient approach. In this paper, vibration modal analysis method using finite element method for multi stage mounting system having n d.o.f model was proposed. Vibration analysis of single and double stage resilient mounting system was performed to verify the validity of the proposed method. Also frequency response results were compared in case of rigid foundation model and finite element foundation model which was compared with experimental modal analysis results.

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