• Proceedings of the Acoustical Society of Korea Conference
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• spring
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• pp.107-110
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• 2000

음성 신호는 시간에 따라 변하지만 일정 구간에서는 특성이 변하지 않는다고 가정하여 윈도우를 취해 단구간 분석을 한다. 이 때 윈도우의 적용은 필수적이다. 하지만 단구간 분석을 위해서 사용되는 윈도우에 의해 생기는 누설에너지 때문에 음성신호의 스펙트럼 정보가 왜곡되어 버린다. 본 논문에서는 스펙트럼 분석 시 발생되는 누설에너지를 최소화하는 방법을 제안하고자 한다. 음성신호에 고정된 크기의 rectangular Window를 취한 후 처음 샘플과 차이가 가장 작은 샘플을 프레임 크기의 3/4인 지점에서부터 검색하여 최소인 부분까지 시간 축 스케일링을 한 후 기존의 윈도우 크기와 같은 크기로 만든다. interpolation과 decimation을 조합하여 시간 축 스케일링을 한다. 이렇게 윈도우가 적용된 신호를 처리 후 위의 역 과정을 수행한다. 제안한 윈도우의 SNRseg는 rectangular window보다 평균 7.88dB 낮고, kaiser window보다 평균 1.65dB 높았다. 또한 제안한 윈도우의 SD는 rectangular window 보다 평균 $1.73dB^\2$ 낮았다.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1994.04a
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• pp.249-249
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• 1994

PAF (Platelet-activating factor: 혈소판 활성화인자)는 1972년 Benveniste등에 의해 토끼의 호중구 배양 상청액중에서 발견되어 1979년 그 구조가 1-alkyl-2-acethyl-sn glycero-3-phosphocholine의 구조를 갖는 에테르형 인 지질임이 밝혀졌다. 그후 혈소판 이외 과립구, 단구나 macrophage, 혈관내피세포등 조직의 염증담당세포가 다양한 자극에 응하여 PAF를 생성됨이 보고되었다. PAF가 나타내는 대표적 활성으로는 혈소판, 호중구, 단구들의 활성화, 호중구의 유주 활성, 혈관투과성 항진, 혈압강하작용. 기관지 수축 등이 알려졌으며. 또한 염증, 알러지, 천식 endotoxin shock 등 여러질병에 직·간접적으로 관여함이 알려졌다. 이와같은 여러 생리 현상은 PAF의 특이적수용체를 개재하여 일어난다는 것이 밝혀졌다. 따라서 PAF의 다양한 질병의 관여가 밝혀짐으로서, PAF길항제의 개발이 활발히 진행되어왔다. 지금까지 PAF길항제의 개발은 PAF 구조 유사체. benzodiazepam유도체, thiazole유도체 등과 같은 합성품과 ginkolide, kadsurenone과 같은 천연물 유리의 것이 알려져 in vivo model에서도 그 효능이 확인되었다. 본 연구는 이와 같은 배경에서 20여 종의 생약에서 PAF 길항제를 검색하던 중 5종류의 생약에서 PAF 길항작용을 갖는 분획을 찾았기에 이에 보고한다.

• Journal of Veterinary Clinics
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• v.7 no.1
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• pp.429-438
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• 1990

The cytochemical characteristics of the hematopoietic cells in blood and bone marrow from 3 clinically healthy dogs were examined using a battery of cytochemical stains. Alkaline phosphotase activity was demonstrated in eosinophilic series and occassionally in progranulocytes. A variety of cells exhibited acid phosphatase activity, but tartrate-resistant acid phosphatase activity was seen only in eosinophilic series. Peroxidase activity was observed in myeloblasts to segmented cells of granulocytic series and in monocytes. ${\alpha}$-naphthyl acetate esterase activity was found in monocytes and occassionally in lymphocytes. Naphthyl-AS-D-chloroacetate esterase marked neutrophilic series from myeloblasts to segmented cells. ${\beta}$-Glucuronidase activity was detected in a variety of cells except the cells of erythrocytic series. Periodic acid Schiff stain-positive granules were demonstrated in the neutrophilic and eosinophilic series from myelocytes to segmented cells and in monocytes and occassionally in lymphocytes. Sudan black B stain-positive granules marked granulocytic series from myeloblasts to segmented tells and monocytes.

• Korean Journal of Soil Science and Fertilizer
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• v.18 no.3
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• pp.289-296
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• 1985

To clarify the soil characteristics and genesis of the clayey terrace soils distributed in Yeongcheon (inland region) and Yeongil (coastal region), 9 typifying pedons including a recent local deposits were studied. The physico-chemical properties found were summarized as follows; 1. The contents of available water of the terrace soils were ranged from 12.0 to 20.3%. They were increased with increaseing clay content up to 35%, and then decreased at clay content of 35 to 55%, but were maintained about 12 to 13% when the clay content exceeds 55%. 2. The amount of water stable aggregates in the surface soils were ranged from 55.0 to 81.1%, and were low in cultivated upland where water erosion were accelerated while high in the paddy where the double cropping were practiced. The index of aggregate in cultivated upland were higher in the surface soils but the paddy soils were higher in subsoils. 3. The colloidal reactions checked by the differences between pH in $0.01N-Na_2SO_4$ and $H_2O$ indicate exchangeable acidity to exchangeable neutrality, which means a sort of Red-yellow soil forming process had been prevailed during genesis of the terrace soils. 4. Cation exchange capacity of the clayey terrace soils were averaged about 15.8-20.2me/100g of fine earth and 35.6-52.6me/100g of clay. The rates of base saturation were 32.7 to 57.6% and the rates decreased with increasing the elevations of terraces. 5. The activities of free iron oxides were 0.061 to 0.739 and the values decreased with increasing elevation while the crystallinity index of iron oxides positively correlated with elevations the values ranged from 0.067 to 0.537.

• Tuberculosis and Respiratory Diseases
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• v.41 no.1
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• pp.11-19
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• 1994

Background: Mycobacterium tuberculosis is a facultative intracellular pathogen which persists and multiplies within macrophage. Competent cell mediated immunity by cooperation of both T lymphocyte and macrophage of the host is required to kill the Mycobacterium tuberculosis. But a precise understanding of the pathogenesis of tuberculosis infection in pulmonary alveolar macrophage has not been achived. Research on the macrophage's basic microbicidal mechanism has elucidated the importance of oxygen-dependent or oxygen-independent components. Oxygen dependent processing begins with the reduction of oxygen by NADPH oxidase and generation of superoxide. In this study, the oxidative metabolic status of blood monocyte and pulmonary alveolar macrophage in patients with active pulmonary tuberculosis was accessed and compared with that of healthy control subjects to know whether there was a basic difference in superoxide generation by mononuclear cells between two groups. Methods: Pulmonary alveolar macrophage was purified after performing BAL(bronchoalveolar lavage) through the bronchi of infected lesion by plastic adhesion method. Blood monocyte was purified by Ficoll-Hypaque method. Superoxide generation by blood monocyte and pulmonary alveolar macrophage was measured by ferricytochrome-C reduction method after either stimulated with PMA(phorbol myristate acerate) or non-stimulated states. We also measured the effect of pulmonary tuberculosis patient's serum on superoxide generation by monocyte. Results: 1) Generation of superoxide by alveolar macrophage obtained from patients with pulmonary tuberculosis was little higher than those of controls, and PMA enhanced the generation of 2) Generation of superoxide by blood monocyte obtained from patients with pulmonary tuberculosis was little higher than those of control(p>0.05), and PMA more enhanced the generation of superoxide in patientswith pulmonary tuberculosis than those in controls(p<0.02). 3) Patient's serum enhanced the generation of superoxide by blood monocyte obtained from patients with pulmonary tuberculosis and controls, but not in the case of PMA stimulated blood monocyte. Conclusion: The present study suggest that the phenomenon of M.tuberculosis escape the microbicidal action of macrophage was not result of suppressed superoxide generation by blood monocyte and pulmonary alveolar macrophage, rather there might be a factor to stimulate the generation of superoxide by blood monocyte in pulmonary tuberculosis patient serum, but the comparision with effect of control's serum on superoxide generation needs further elucidation.

• Korean Journal of Soil Science and Fertilizer
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• v.19 no.3
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• pp.205-210
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• 1986

A soil micromorphological study of clayey terrace soils in Yeongnam area was carried out to investigate the soil genetic features and to distinguish the soil parent materials. Dominant plasmic fabrics in the terrace soils were vosepic, mosepic, insepic, and masepic of sepic fabrics but the Geugrag and Upyeong in Yeongil sequence have an asepic fabrics. Embedded grain cutans in the terrace soils were characterized by having porphyroskelic related distribution. Among pedological features of the B horizons of the terrace soils, the argillic cutans of ferriargillans and glaebules of manganiferrous concretions were the dominant in mineralogical composition, and the papules are abundant in the most terrace soils indicating that the soils are generally old. The substrata of the Bancheon in Yeongcheon and Upyeong in Yeongil area were so different from the terrace deposits in plasmic fabrics that these soils were believed to be composed of bisequum profiles. Because of having the free grain cutans, it was considered that the substrata of Bancheon in Yeongcheon and Upyeong in Yeongil area might have a period of soil formation before deposition of the terrace materials.

• Journal of the Korean association of regional geographers
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• v.14 no.2
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• pp.173-188
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• 2008

In order to make comparative analysis of geomorphological changes caused by urban development, I surveyed the distribution of geomorphological resources of 'Daegu Innovation Town' development plan area. The results are as follow: (1) At the front of small valleys of back-mountains are formed small alluvial fans, and at the side of small valleys are distributed hills connected with back-mountains. (2) As small valley erode laterally hills, vertical bluffs and planner bedrock riverbed are formed, and in some riverbed are appeared mud cracks and ripple marks. (3) The depth of valley in alluvial fan of 'Sinseo District' is 7m. In Sinseocheon valley dissecting alluvial fan, fluvial terraces 2m high above riverbed are distributed. Those terraces were formed while alluvial fan was dissected after last glacial period.

• Journal of The Geomorphological Association of Korea
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• v.18 no.4
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• pp.213-221
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• 2011

The purpose of this study is to clarify the characteristics of forms and distributions of Gapyoungchon potholes. Different sizes of 153 potholes were distributed in the upper stream marginal area that was 30×25m, and over 70 percent among them were egg-shaped potholes. A development of joint in pothole was not important to make potholes in the stream but the mean size of potholes with joint was larger than without joint. Moreover, the schistosity structure of the bedrock was more important factor to develop potholes in this area. Finally, four cross sectional faces were found in this study area. From the reason, Gapyoungchon potholes are distributed on the rock terraces.

• Journal of Life Science
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• v.18 no.4
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• pp.537-541
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• 2008

White adipose tissue is now recognized as an important endocrine organ which secretes various signal factors and proteins termed 'adipokine'. Haptoglobin (Hp), which has been known as an acute phase protein, belongs to the adipokine. However, the function of Hp in adipose tissue remains unclear. To verify the role of Hp in preadipocytes, in this study, 3T3-L1 preadipocyte cells were stably transfected with human Hp gene and Hp-overexpressing cells were made. The Hp had no effect on cell growth of preadipocytes. By RT-PCR and Western blot analysis, the Hp inhibited gene expression of IL-6 and COX-2 and enhanced HO-1 synthesis in preadipocytes. Moreover, invasion assay showed the Hp suppressed migration of monocytes to preadipocytes. These findings suggest that the Hp may inhibit an inflammatory reaction in adipose tissue by regulating the expressions of pro-inflammatory and anti-inflammatory mediators, and by repressing monocytes/macrophages infiltration.

• Journal of The Geomorphological Association of Korea
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• v.24 no.2
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• pp.15-25
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• 2017

Subi basin is located at the crestline of Taebaek mountains. This paper aims to elucidate the geomorphic development of Subi basin through the analysis of river terraces built in Wangpi-cheon and Banbyeon-cheon. Wangpi-cheon flows northeastward from Subi basin, and Banbyeon-cheon flows southward at the west of Subi basin. Absolute age of terrace is measured by means of OSL methodology, long profile of Wangpi-cheon is made up with 10m interval contour line, and the elevation above river bed of high terraces is measured at the end part of terrace. The results are as follow: Firstly, high river terraces of Subi basin, Wangpi-cheon and Banbyeon-cheon are formed about 40 kyr(MIS 3) being interstadial stage of last glacial period. Secondly, the elevation above river bed of high terraces of Wangpi-cheon and Banbyeon-cheon tends to increase toward upstream. It means that the uplift of Taebaek Mountains influences considerably the formation of their terraces. Thirdly, the elevation above river bed of high terraces at the reach from Seomchon to Suha-ri of Wangpi-cheon tends to decrease toward upstream. This section is captured from Banbyeon-cheon flowing in the opposite direction. River piracy has occurred from the time of formation of Suha-ri high terrace to the time of formation of Hantee wind gap. Finally, for fluvial system of Wangpi-cheon to establish dynamic equilibrium, topographic axis will move toward Banbyeon-cheon.