• Journal of Pharmaceutical Investigation
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• v.41 no.6
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• pp.323-329
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• 2011

In order to develop new protein carrier replacing poly(DL-lactic acid-co-glycolic acid) (PLGA) microspheres, succinylated pullulan acetate (SPA) was investigated to fabricate a long term protein delivery carrier. SPA microspheres loaded with lysozyme (Lys) as a model protein drug were prepared by a water/oil/water (W/O/W) double emulsion method. An acidity test of SPA copolymers after hydrolysis was performed to estimate the change of protein stability during releasing proteins from the microspheres. There was no pH change of SPA copolymers, but pH of PLGA polymers after hydrolysis was significantly decreased to around pH 2, indicating that the long-term stability of proteins released from SPA microspheres can be guaranteed. Loading efficiency of proteins into SPA microspheres was three times higher than those into conventional PLGA microspheres, indication of inducing stronger charge interaction between proteins and succinyl groups in SPA microspheres. Although initial burst behaviors were monitored in Lys-loaded SPA microspheres due to relatively strong hydrophilic succinyl segments in SPA microspheres, initial burst issues would be circumvented if the ratio of charge density of succinyl moieties and hydrophobic acetate groups is harmonically controlled. Therefore, in this study, a new attempt of protein delivery system was made and functional SPA was successfully confirmed as a new protein carrier.

• Fashion & Textile Research Journal
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• v.17 no.1
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• pp.74-81
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• 2015

This study explored the degree of cognition, purchasing experience and attitudes towards SPA brand attributes. This study examined the differences in variables and demographic characteristics against appearance interest groups. A questionnaire survey collected data from November $1^{st}$ and $15^{th}$ 2012. The convenience sample was drawn from females between the ages of 20 and 39 who lived in the Daegu and Gyeongbuk regions of South Korea. A total of 255 responses were complete and usable questionnaires. Data were tested through factor analysis, t-test, and ${\chi}^2$ test using SPSS 21.0. The results show that there were significant group differences in the cognition and purchasing experience of SPA brands and the attitudes towards SPA brand attributes. The high appearance interest group was more aware of SPA brands and evaluated SPA brand attributes more positively and bought more SPA brand products than the low appearance interest group. The high appearance interest group showed that domestic brands were excellent in low price among brand attributes but foreign brands were relatively excellent in various design and store display. There was a significant difference in educational level between appearance interest groups; however, there were no significant differences in age, marital status, and income level group. This study contributes to basic information for the SPA brand buying behavior research field and apparel industry marketing strategy by analyzing the relationship among appearance interest, cognition, SPA brand purchasing experience and SPA brand attribute attitudes.

• Journal of Fashion Business
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• v.19 no.5
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• pp.139-156
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• 2015

The purpose of this study is to investigate various information relating to research on the dimensions of clothing used in the sale of products via the internet that used to target global SPA((Specialty Store Retailer of Private Label Apparel) brands sold in Korea. A total of 12 SPA brands including seven global SPA brands and five national. SPA brands were surveyed in this study. Brands were chosen net sales and consumer preferences the last three years. In all SPA brands, literal size designation such as S, M, L and numeric size designation such as 0, 2, 4 or 32, 34, 36 etc. were mixed, but in case of Jean, the size codes mark waist circumference were dominant. European size codes were more common in case of European brands while literal codes were more dominantly used for American size codes with in the US brands. By reviewing the measurement information of the body and product size, the product measurement methods of UNIQLO, FOREVER 21 and TOPTEN were much more accountable and excellent than other brands. However, most of the others didn't offer proper information such as pictograms or figures about measurement methods relating body sizes and product sizes. In addition, most of global SPA brands offered size conversion chart which consumers could reference, however of none of the national SPA brands offered a conversion size chart on their website. Regardless of the type of clothing, the coverage of clothing size was higher than in global SPA brands such as H&M GAP compared to national SPA brands. In particular, 8seconds did not present apparel size ranges that fit consumers' individual clothes sizes.

• Archives of Pharmacal Research
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• v.26 no.10
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• pp.821-825
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• 2003

The effects of purple sweet potato anthocyanin (SPA) and Cordyceps mushroom extract (CME) on lipid peroxidation, 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals and cognitive deficits were examined. Both SPA and CME exhibited DPPH radical scavenging activities with similar potency. In contrast, only SPA was shown to effectively inhibit lipid peroxidation initiated by $Fe^{2+}$ and ascorbic acid in rat brain homogenates. Furthermore, SPA markedly enhanced cognitive performance, assessed by passive avoidance test in ethanol-treated mice. Combined treatments with SPA and CME did not significantly influence the effects of SPA alone. These results demonstrate that anthocyanin prepared from purple sweet potato exhibits memory enhancing effects, which may be associated with its antioxidant properties.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.17 no.1
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• pp.21-32
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• 2007

Vuillaume-Okeya presented unsigned receding methods for protecting modular exponentiations against side channel attacks, which are suitable for tamper-resistant implementations of RSA or DSA which does not benefit from cheap inversions. The proposed method was using a signed representation with digits set ${1,2,{\cdots},2^{\omega}-1}$, where 0 is absent. This receding method was designed to be computed only from the right-to-left, i.e., it is necessary to finish the receding and to store the receded string before starting the left-to-right evaluation stage. This paper describes new receding methods for producing SPA-resistant unsigned representations which are scanned from left to right contrary to the previous ones. Our contributions are as follows; (1) SPA-resistant unsigned left-to-right receding with general width-${\omega}$, (2) special case when ${\omega}=1$, i.e., unsigned binary representation using the digit set {1,2}, (3) SPA-resistant unsigned left-to-right Comb receding, (4) extension to unsigned radix-${\gamma}$ left-to-right receding secure against SPA. Hence, these left-to-right methods are suitable for implementing on memory limited devices such as smartcards and sensor nodes

• Korean Institute of Interior Design Journal
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• v.21 no.2
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• pp.123-132
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• 2012

In the trend of concentrating on the consumer driven experience market as a new marketing concept according to the improvement of life standard and the change of consummation pattern, SPA brand has applied experience marketing strategies to the market successfully to be grown constantly with consumer secure and production of business benefit through brand image and positive consumer attraction. Therefore, this study aims to research the experiential representation element and attribute in the competitive Global SPA brand space due to the sustainable growth from the recent domestic fashion market based on the strategy type of the experiential marketing. Thus, the experiential marketing strategy type was drawn based on the experiential marketing and the theoretical reflections of Global SPA brand, and the SPA brand space was classified depending on the attribute of the commercial space for making the framework of case analysis, so it was progressed as the method of analysis through the experiential representation attribute in the SPA brand space. The marketing strategy and representation for advertising the image of company and product message by the SPA brand should be planned, so successful application of the experiential marketing to the shop is connected to the corporate interests, and forming the meaning more than space by impressing on the consumers the brand and arousing the emotional experience of the consumers and meeting the consumers' a variety of needs had effects on forming a lasting relationship between the brand and consumers. Therefore, this study is expected to be an opportunity to vitalize the domestic SPA brand behind the competition with the Global SPA brand.

• Animal Bioscience
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• v.34 no.2
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• pp.285-294
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• 2021

Objective: This study was conducted to investigate the supplementary effect of a phytogenic blend (SPA: a mixture containing fermented Schisandra chinensis pomace, fermented Pinus densiflora needle extract, and Allium tuberosum powder in the ratio of 2:2:1) on egg production, egg quality, blood constituents, and visceral organs in laying hens. Methods: A total of 135 Hy-line brown laying hens (48-wk-old) were randomly allocated to three dietary treatments with 5 replicates of 9 hens. The control group (CON) was fed a basal diet (no exogenous SPA addition) and the experimental groups were fed the basal diet containing SPA at the level of 0.1% and 0.3% for 6 weeks. Results: The feed intake was significantly improved in SPA supplemented groups as compared with the control (p<0.05). However, egg production, daily egg mass, and feed conversion ratio were not different among the dietary treatments (p>0.05). For egg quality traits, only Haugh unit (HU) was significantly improved in SPA (0.3%) (p<0.05) as compared with other groups. However, HU was not affected during 4-wk of storage at 18℃ among the dietary treatments (p>0.05). Furthermore, SPA supplementation did not affect the blood biochemical constituents except for the phosphate content, which was significantly higher in SPA groups than the CON group (p<0.05). There were no significant differences in visceral organ characteristics and immune indicators (immunoglobulin A [IgA], IgG, and IgM) in SPA or CON groups. Conclusion: This study suggested that the supplementation of SPA may have beneficial effects on feed intake and egg quality in laying hens.

• Journal of the Korean Society of Fashion and Beauty
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• v.3 no.3 s.3
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• pp.64-70
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• 2005

The purpose of this study was to give help for more activation to the area of spa industry appropriate to the emotion of our country based on the spa of recognition of massage specialist. Aroma Essencial oil bath was the first favorite of the customers when they're going to have bath in Hydro-therapy or with some other material in their bathtub according to the general results of the previous study. The most high voice of discontent of customers was the high price and the main customer's ages on the spa-therapy were the ages 30s and 40s. The method for activation for future spa-therapy were showed as the better facilities and advertising, reasonable price, systematic education programs, professionalists as an order. The proper care hours for spa-therapy that customers like most was 1:30-2:30 and the resonable price of one time care of that was shown as 100,000-200,000 won. The priority actions for the competition with foreigners on this area of spa-therapy will be the various and nation-wide advertisement of the effectiveness on spa-therapy to the customers to use easily and to be made being generalized on their lives. And the our inland spa-therapy must have main position at the center of cities, the various programs to satisfy the Korean traditional culture of them should be studied and introduced. And at that time future inland spa-therapy industry will have power for the competitions with similar foreign industries.

• Journal of the Korea Fashion and Costume Design Association
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• v.14 no.1
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• pp.131-150
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• 2012

The purpose of this study is to provide the characteristics of marketing strategy on the SPA(Specialty store retailor of Private label Apparel) brand. This research can be used as information for the domestic SPA brand to enhance its international competitiveness. The characteristics of marketing strategy on the SPA brand are as follows. 1. One company integrate vertically the process of planning, production, promotion and distribution. 2. As using the advanced information, productions, and logistics systems, they are carried out speedy management. 3. The production strategies are focused on providing new goods of fast cycle and very diverse styles in a season, developing products that accurately reflect the general market trend and consumer demands, extending the line of goods, outsourcing of the place to reduce production costs. For high-quality goods, they are collaborating with the famous designers and developing of new and green environment materials. 4. Generally, the SPA brand emphasizes the low price strategy against the quality. 5. The promotion strategies are focused on conducting various unique and high sensible VMDs, fashion shows, star marketing, campaigns, aggressive publicity, magazine & outdoor advertisement and various events through the internet website, etc. 6. The place (distribution) strategies of SPA brand are focused on launching into global, expanding number of stores, increasing large-sized stores and diversifying the forms of store and selling.

• Fashion & Textile Research Journal
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• v.16 no.4
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• pp.604-613
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• 2014

The purposes of this study were to classify respondents by their fashion lifestyle and to investigate the differences in cognition, attitude and purchasing experience of SPA brands among fashion lifestyle groups. The convenience sample was drawn from females between the ages of 20 and 39 who lived in Daegu and Gyeongbuk regions from November $1^{st}$ and $15^{th}$ 2012. Descriptive statistics, cluster analysis, ANOVA, Tukey test, and ${\chi}^2$ test were applied to analyze data from 255 respondents. Four clusters (fashion-oriented group, fashion indifferent group, conservative individuality-oriented group, conservative practicality-oriented group) were developed by 16 fashion lifestyle items. The attitude toward SPA brand was classified by six factors(fashionability/variety, good location, good quality, diverse promotions, low price, limited number of merchandise, sales person's information). There were significant differences in cognition, five attitude factors (fashionability/variety, good location, good quality, low price, limited number of merchandise) and purchasing experience of SPA brands among types of fashion lifestyle. While the fashion-oriented group had the highest scores of cognition, attitude and purchasing experience of SPA brands, the fashion indifferent group or the conservative practicality-oriented group had the lowest scores. There were significant differences in age and marital status among the four groups while there were no significant differences in marital status, family monthly income, and job.