• Proceedings of the Korean Fiber Society Conference
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• 1989.06a
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• pp.28-29
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• 1989

• Journal of the Korean Home Economics Association
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• v.28 no.3
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• pp.127-145
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• 1990

The purpose of this study was to investigate a framework for family stress management. The subjects were 287 housewives habitated in Seoul. Cronbach's α, Pearson's r, Factor analysis, ANOVA, Frequency, Percent, Duncan's Multiple Range Test were conducted for the purpose of the study.

• Journal of Welding and Joining
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• v.22 no.4
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• pp.24-28
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• 2004

마이크로 접합 공정은 미세 부품이나 박판의 접합에 사용되며, 이를 위해 다양한 공정이 개발되었다. 최근 MEMS(Micro Electro Mechanical System)활용 범위가 증가하고 있으며, MEMS에 사용되는 미세한 구조물의 접합이나 패키징에 접합 공정이 활용되고 있다. MEMS는 발전 단계이지만 전자 패키징(electronic packaging)은 성숙 단계인 반도체 산업에 사용되고 있다.(중략)

• Proceedings of the KIPE Conference
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• 2010.11a
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• pp.28-29
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• 2010

• Asian-Australasian Journal of Animal Sciences
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• v.33 no.4
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• pp.670-677
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• 2020

Objective: Interleukin-6 (IL-6) is a T cell-derived B cell stimulating factor which plays an important role in inflammatory diseases. In this study, the pharmacokinetic properties of LMT-28 including physicochemical property, in vitro liver microsomal stability and an in vivo pharmacokinetic study using BALB/c mice were characterized. Methods: LMT-28 has been synthesized and is being developed as a novel therapeutic IL-6 inhibitor. The physicochemical properties and in vitro pharmacokinetic profiles such as liver microsomal stability and Madin-Darby canine kidney (MDCK) cell permeability assay were examined. For in vivo pharmacokinetic studies, pharmacokinetic parameters using BALB/c mice were calculated. Results: The logarithm of the partition coefficient value (LogP; 3.65) and the apparent permeability coefficient values (P_app; 9.7×10^-6 cm/s) showed that LMT-28 possesses a moderate-high cell permeability property across MDCK cell monolayers. The plasma protein binding rate of LMT-28 was 92.4% and mostly bound to serum albumin. The metabolic half-life (t_1/2) values of LMT-28 were 15.3 min for rat and 21.9 min for human at the concentration 1 μM. The area under the plasma drug concentration-time curve and C_max after oral administration (5 mg/kg) of LMT-28 were 302±209 h·ng/mL and 137±100 ng/mL, respectively. Conclusion: These data suggest that LMT-28 may have good physicochemical and pharmacokinetic properties and may be a novel oral drug candidate as the first synthetic IL-6 inhibitor to ameliorate mammalian inflammation.

• Electronics and Telecommunications Trends
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• v.22 no.1 s.103
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• pp.140-150
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• 2007

차세대 유무선 통신망이 급속하게 All-IP 기반으로 전환되어 감에 따라 전세계적으로 인터넷전화 서비스가 기존 유선전화를 빠르게 대체해 나가고 있다. 그러나, 이와 관련된 적절한 규제없이 서비스가 진행됨에 따라 시민의 안전을 위협하는 사례가 발생되고있다. 따라서, 미국의 연방통신위원회(FCC)에서는 2005년 5월 인터넷전화 서비스 제공업체에게 긴급통화 서비스 제공에 대한 의무를 규정한 VoIP E911 고시(order)를 제정하였다. VoIP E911 고시는 고시의 대상이 되는 서비스를 정의하고, 고시의 발표일이후 120일 이내인 2005년 11월 28일까지 E911 서비스 요구사항을 준수하라는 내용을 담고 있다. 이후 2005년 11월 7일에 연방통신위원회(FCC)에서는 인터넷전화 서비스 제공업체들에게 VoIP E911 고시의 이행현황에 대하여 2005년 11월 28일까지 제출하라고 하였다. 따라서, 본 고에서는 연방통신위원회(FCC)의 VoIP E911 고시(order)를 중심으로 미국의 VoIP 긴급통화 정책동향에 대하여 분석하고자 한다.

• Bulletin of the Korean Chemical Society
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• v.28 no.10
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• pp.1756-1762
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• 2007

Envelope proteins of virus contain a segment of hydrophobic amino acids, called as fusion peptide, which triggers membrane fusion by insertion into membrane and perturbation of lipid bilayer structure. Potential fusion peptide sequences have been identified in the middle of L or M proteins or at the N-terminus of S protein in the envelope of human hepatitis B virus (HBV). Two 16-mer peptides representing the N-terminal fusion peptide of the S protein and the internal fusion peptide in L protein were synthesized, and their membrane disrupting activities were characterized. The internal fusion peptide in L protein showed higher activity of liposome leakage and hemolysis of human red blood cells than the N-terminal fusion peptide of S protein. Also, the membrane disrupting activity of the extracellular domain of L protein significantly increased when the internal fusion peptide region was exposed to N-terminus by the treatment of V8 protease. These results indicate that the internal fusion peptide region of L protein could activate membrane fusion when it is exposed by proteolysis.

• Journal of the Korean Data and Information Science Society
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• v.28 no.5
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• pp.1191-1204
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• 2017

Weighted least squares (WLS) estimation is often easily used for the data with heteroscedastic errors because it is intuitive and computationally inexpensive. However, WLS estimator is less robust to a few outliers and sometimes it may be inefficient. In order to overcome robustness problems, Box-Cox transformation, Huber's M estimation, bisquare estimation, and Yohai's MM estimation have been proposed. Also, more efficient estimations than WLS have been suggested such as Bayesian methods (Cepeda and Achcar, 2009) and semiparametric methods (Kim and Ma, 2012) in heteroscedastic error models. Recently, Çelik (2015) proposed the weight methods applicable to the heteroscedasticity patterns including butterfly-distributed residuals and megaphone-shaped residuals. In this paper, we review heteroscedastic regression estimators related to robust or efficient estimation and describe their properties. Also, we analyze cost data of U.S. Electricity Producers in 1955 using the methods discussed in the paper.

• The Korean Journal of Applied Statistics
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• v.28 no.3
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• pp.583-592
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• 2015

Zero-inflation has recently attracted much attention in integer-valued time series. This article deals with conditional variance (volatility) modeling for the zero-inflated count time series. We incorporate zero-inflation property into integer-valued GARCH (INGARCH) via conditional Poisson and negative binomial marginals. The Cholera frequency time series is analyzed as a data application. Estimation is carried out using EM-algorithm as suggested by Zhu (2012).

• Journal of Chest Surgery
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• v.28 no.3
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• pp.320-323
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• 1995

We report a case of recurred Takayasu,s arteritis.The patient was 28-year-old female underwent aorto-left common carotid and aorto-left subclavian bypass graft replacement 1 year ago.Unfortunately, she was readmitted because of newly developing angina and both eye claudication severe headache. Aorto-coronary angiogram showed complete obstruction of left common carotid artery ,stenosis of right carotid artery bifurcation and ostial stenosis of right coronary artery.Bilateral carotid arteries bypass graft with great saphenous vein and right coronary artery bypass graft with right internal mammary artery were done at same the time and she discharged after 21 days without any problem.