• Journal of Biomedical Engineering Research
• /
• v.19 no.4
• /
• pp.379-384
• /
• 1998

To measure precisely the blood velocity in the skin microcirculation, we have used time domain correlation (called Cross-Correlation) based on the processing of the backscattered RF signal obtained with a wideband echographic imaging transducer, although it is difficulties of adaptation of the pulsed wave system, because of the data processing in real time and the hardware problem. This dedicated technology based on a 20MHz echographic imaging system has been developed. We present how the experimental data, i.e. the backscattered RF signal, have to be analyzed. After RF lines realignment, stationary echo canceling procedure and correlation level control, a velocity profile has been obtained. In-vitro result show that velocity measurements as low as 0.1mm/sec attainable with a 80${\mu}m$ in axial resolution. We have also validated with in-vivo experimentation on the external ear of a rabbit using B-mode sector scanning image and M-mode image of a custom made 20MHz skin image system. The flow of the "auriculares caudales" vein, a microvessel of 600 m diameter, has been detected and studied. This technique will allow a more precise exploration of circulatory troubles in cutaneous pathologies.

• Journal of the Korean Institute of Telematics and Electronics S
• /
• v.35S no.6
• /
• pp.66-71
• /
• 1998

High spatial resolution ultrasonic imaging is necessary in several fields of investigation, in order to permit greater precision of clinical diagnosis in the dermatology, ophthalmology etc. We present a B-mode scan system using sector scanning probe of 20MHz center frequency. This developed system allow the high resolution image of 250${\mu}m$ in lateral and 80${\mu}m$ in axial, which of display the size of a $5mm {\times} 5mm$ image with 20 frames/sec. We have shown the images of various structural elements of the human skin and of the nail. We have compared the skin images obtained for each of the different age and we have shown in a general with the age, the atrophy of the skin thickness and the appearance of the abnormal hypoechogene band under epidermis (named SENEB : Sub Epidermal Non Echogene Band).