• Korean Journal of Biological Psychiatry
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• v.6 no.2
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• pp.253-258
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• 1999

The fluoxetine is one of the most frequently prescribed drugs for the treatment of depression and obsessive-compulsive disorder(OCD). This has been known as one of the most safest medication. But since the advent of this drug, there have been several reports of side effects-the mania and suicidal ideation-encountered during coadministration of fluoxetine with or without other psychotropic drugs. We experienced a case of 20 years old male OCD patient who developed into abrupt manic state and also was preoccupied with intense suicidal ideation following fluoxetine use. He was a only child in his family and his father had a history of alcoholism about 15years ago. Our patient's obsessive-compulsive symptoms have been occured since puberty. His OCD symptoms and anxiety were aggravated since joining the army. Beside these facts, we could not find any other psychiatric history such as depressive disoder and bipolar disorder. We used the fluoxetine starting dosage of 20mg and increased to 40mg at second week. About 3 weeks after the treatment, he developed sudden manic symptom and more aggravated suicidal ideation without any OCD symptoms. He felt vitalized and energetic without having enough sleep and food. These symptoms were ceased over two weeks by stopping medication. Up to this point, the reason why fluoxetine induces mania and suicidal preoccupation is unclear. But somehow the fluoxetine has effects on serotonin receptor and serotonin-dopamine regulations, thus we could make an assumption that fluoxetine can induce mania, extrapyramidal symptoms(EPS) and suicidal ideation in some part of the serotonin unbalanced patients. We think this would be the first report to remark on fluoxetine's suicidal and manic side effects in Korea. So here we present the case with the summary of reviewed articles.

• Journal of the Korea Computer Industry Society
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• v.2 no.8
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• pp.1055-1062
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• 2001

Study, it is the purpose to develope a cheap and compact pulsed $CO_2$ laser with pulse repetition rate range of 1 KHz. We used a IGBT switched power supply as a power supply, which is cheap and simple comparing to others. PIC one-chip microprocessor was used for precise control of a laser power supply on the control part. And the laser cavity was fabricated as an axial and water cooled type. The laser performance characteristics as various parameters, such as pulse repetition rate, gas pressure, and gas mixture rate have been investigated. The experiment was done under the condition of total pressure of $CO_2$： $N_2$：He ＝ 1：3：10, 1：1.5：5, 1：9：15 from 6 Torr to 15 Torr and pulse repetition rate from 100 Hz to 900 Hz. As a result, the maximum average outpu was about 20.5 W at the total pressure of 15 Torr, the gas mixture $CO_2$：$N_2$：He ＝ 1：9：15 and the pulse repetition rate of 700 Hz.

• Journal of Fashion Business
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• v.20 no.1
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• pp.82-97
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• 2016

This study attempted to summarize the characteristics of fashion in the 1930s which were the background of 'Bonnie and Clyde' and analyze how fashion in the 1930s was expressed through costume in the movie, focusing on some critical scenes. For this, previous studies and domestic & foreign books, magazines and DVDs relating to movie costume were examined. For analysis of movie costume, 'Bonnie and Clyde (1967)' DVD was referred to. In the movie, meaningful scenes were captured using a GOM Player. Then, the study results found the followings: First, in terms of women's fashion in the 1930s, adult look and slim & long silhouette which naturally revealed breast, waist and hip with a long skirt, a military look with strong shoulders and tailored costume were found. In terms of men's fashion, in contrast, the Duke of Windsor Style (a slim silhouette jacket and loose pants) was popular. Second, in the movie, Bonnie's costume started with a slim linen H-line dress at her first meeting with Clyde. While committing crimes and becoming a famous gangster, she displayed the fashion styles which were in vogue in the 1930s such as fancy and luxurious slim dress, tailored suit and trench coat. Third, in terms of Clyde's costume, from his first meeting with Bonnie to his first crime, he put on common costume (ex: pants, vest, shirts, etc.) which revealed his open and unconventional character. After he became a famous gangster, he would wear the Duke of Windsor style (jacket, vest and pants). The study results well describe movie costume's role as visual language which expresses characters' inner circumstances and outer situations that reflect socio-cultural background.

• Journal of Microbiology and Biotechnology
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• v.25 no.12
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• pp.1989-1996
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• 2015

Ice-binding proteins (IBPs) can inhibit ice recrystallization (IR), a major cause of cell death during cryopreservation. IBPs are hypothesized to improve cell viability after cryopreservation by alleviating the cryoinjury caused by IR. In our previous studies, we showed that supplementation of the freezing medium with the recombinant IBP of the Arctic yeast Glaciozyma sp. (designated as LeIBP) could reduce post-thaw hemolysis of human red blood cells and increase the survival of cryopreserved diatoms. Here, we showed that LeIBP could improve the viability of cryopreserved mammalian cells. Human cervical cancer cells (HeLa), mouse fibroblasts (NIH/3T3), human preosteoblasts (MC3T3-E1), Chinese hamster ovary cells (CHO-K1), and human keratinocytes (HaCaT) were evaluated. These mammalian cells were frozen in dimethyl sulfoxide (DMSO)/fetal bovine serum (FBS) solution with or without 0.1 mg/ml LeIBP at a cooling rate of -1℃/min in a -80℃ freezer overnight. The minimum effective concentration (0.1 mg/ml) of LeIBP was determined, based on the viability of HeLa cells after treatment with LeIBP during cryopreservation and the IR inhibition assay results. The post-thaw viability of mammalian cells was examined. In all cases, cell viability was significantly enhanced by more than 10% by LeIBP supplementation in 5% DMSO/5% FBS: viability increased by 20% for HeLa cells, 28% for NIH/3T3 cells, 21% for MC3T3-E1, 10% for CHO-K1, and 20% for HaCaT. Furthermore, addition of LeIBP reduced the concentrations of toxic DMSO and FBS down to 5%. Therefore, we demonstrated that LeIBP can increase the viability of cryopreserved mammalian cells by inhibiting IR.

• Journal of Pharmacopuncture
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• v.20 no.3
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• pp.227-229
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• 2017

Fibrosis of skeletal muscle following acupuncture is an iatrogenic disorder. The present case illustrates a patient with a unilateral fibrotic formation on a thumb muscle after acupuncture injection therapy with red sage. The patient in the present case was a counter-terrorism police officer with right-handedness; he noted a palpable nodule three months after injection therapy at his left first dorsal interosseous in which the acupuncture point LI4 (He Gu) is located. He also found a reduction in the strength of his left pinch grip that noticeably affected his left handgun marksmanship. However, being ambidextrous in single-hand pistol shooting is an essential requirement for counter-terrorism police officers. Based on the patient's medical history and claims, no underlying disease or trauma was found to be associated with his current complaint. During physical examination, a fibrotic formation in his left first dorsal interosseous muscle was visualized by using diagnostic ultrasound; also, as confirmed with dynamometry, the strength of his left pinch grip was significantly lower than that of the right counterpart. Because acupuncture injection therapy has three components, antiseptic practices, the mechanical action of syringe insertion, and the pharmacological effect of the sterile herb extract, any one of the components may have contributed to the present adverse event. The first dorsal interosseous muscle is small in dimension and rather vascular; thus, it is not an ideal site for intramuscular injection. When a clinician needs to treat a patient by performing acupuncture at the LI4 acupoint and injecting a herbal extract simultaneously, the clinician should only mechanically stimulate the LI4 acupoint while injecting the herbal medicine into the LI14 (Bi Noe) acupoint on the same meridian, the LI14 acupoint being located in the distal portion of the deltoid muscle and being fairly close to the universally agreed upon site on the upper arm for safe administration of an injection.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.3
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• pp.263-268
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• 2019

This article intends to shed a light on the British architect Arthur S. Dixon (1856-1929). He is largely regarded as a pioneer of the English Art and Craft Movement, yet his works are not widely known nor carefully studied. In search of Dixon's architectural characteristics, this paper examined three notable buildings that he designed at the turn of the nineteenth century; Birmingham Guildhall, St. Andrews church and St. Basil's Church. These buildings were erected relatively early in his career as an architect, although he never fully immersed into the profession due to his commitment in family business management. His architectural design shows unique qualities of Art and Craft movement in terms of use of material, spatial arrangement, techniques, and craftsmanship while employing Romanesque as most relevant historic style for ecclesiastical purposes.

• Journal of architectural history
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• v.20 no.4
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• pp.29-44
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• 2011

Imre Makovecz, a Hungarian architect, has chiefly known for his unique organic works. He has taken a lot of sharp criticism against mere functionalistic and stylistic approaches toward modern architecture. Instead, he has desired to pursue a true embodiment for organic beauty and hungarian cultural heritage in architecture. Although most of his works reside in Hungary, he has become an internationally recognised architect for his unique works. This article attempts to identify Hungarian culture and its influence to Makovecz's architecture. It also examines how Makovecz investigated Hungarian folk art traditions and primitive craft patterns, and then applied the lessons learned into his own architectural designs. Then, this article attempts to expose the principles of his organic architecture deeply influenced by the philosophy of Rudolf Steiner. Finally, it concludes with a discussion of the benefits and challenges of employing similar approaches for the development of a rich architectural tradition.

• Korean Institute of Interior Design Journal
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• v.20 no.6
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• pp.145-152
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• 2011

Salvador Dali put a title of his work as 'A Propos of the Treatise on Cubic Form by Juan de Herrera' at 1960. Through this work which is consisted in cube frame surrounding black and white letter squares and nails in the sky, he directly referred about the cube which were showed in his pictures. To understand the meaning of this work, Dali's paintings and Juan de Herrera's design and architectural ideas are analysed by building. His concerning about absolute existence like god and nuclear takes the cubic form by Juan de Herrera instead of pictorial tendencies of Cubism, however pictorial elements such as sky and nails were still used in the work. He use alphabet letter as pattern consisting wall and symbol representing 'Juan de Herrera', moreover number '2' is taken to show up line attribute. Dali had several design develop process, and finally he reached an new stage called 'Hypercube'. Hypercube can distinguish from Cubism and Herrera's architectural idea, and it will be free from objective world based in Euclid geometry. Although cubic is the simplest shape. It can contain the variety of developments in these fields - philosophy, architecture, painting and etc.- from Platon to nuclear physics and coexists in a picture of Salvador Dali.

• Journal of architectural history
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• v.29 no.3
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• pp.37-50
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• 2020

This research focuses on the life and works of architect Yi Hunwoo, who was active in early 20th century. Yi has been previously mentioned in a few research documents, but not as a main subject of interest. Thanks to digitalized historic databases, the authors of this research were able to access more information about Yi. It was discovered that he was born in Korea in the late 19th century and then attended the Nagoya Higher Technical School in Japan. After repatriation, he participated in a few public projects in Korea as an in-house architect at the Governor-General's office, then started his own practice and produced his individual projects. He also contributed articles on innovations in residential design to newspapers. Chronologically, his activities as an architect preceeded those of Park Gilyong, who has been conventionally regarded as the first Korean modern architect so far. This research would like to establish Yi Hunwoo as a historic figure whose professional career spanned the earlier stage of the Korean modern architecture, based on the records of his life and professional activities. The authors do not wish to present the architectural analysis nor evaluation of his works, which will be subject to future researches.

• Archives of Plastic Surgery
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• v.42 no.2
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• pp.214-217
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• 2015

Blepharoptosis is a common indication for surgery in plastic surgery units, yet its possible underlying pathology frequently remains unidentified. A 52-year-old man with a 20-year history of progressive bilateral ptosis (right>left) presented with recurrent ptosis of both eyes; he had undergone an operation on the levator aponeurosis 12 years prior. Due to the suspicion of an underlying disease, he was evaluated further. Chronic progressive external ophthalmoplegia in transition to the more severe syndromic variant Kearns-Sayre syndrome, a mitochondrial disorder causing myopathy, was diagnosed. The patient was treated with coenzyme Q10, and he underwent ptosis surgery on both eyes. This case illustrates a potentially multi-systemic disease that was diagnosed by a further evaluation of a common symptom, in this case worsening blepharoptosis. Awareness of myopathic symptoms is necessary to prevent overlooking serious yet improvable conditions.