• Bulletin of the Korean Chemical Society
• /
• 제16권7호
• /
• pp.670-672
• /
• 1995

• 약학회지
• /
• 제30권3호
• /
• pp.121-127
• /
• 1986

Three new alkanol esters of d-2-(6-methoxy-2-naphthyl)propionic acid, NAPROXEN were synthesized by esterification of sodium naproxen with chloralcohols, such as 2-chloroethanol, 3-chloro-1, 2-propanediol and $\beta$-chloroethoxyethanol in dimethylformamide. These new esters were obtained with comparably high yield and identified by elemental analysis, UV, IR and NMR techniques.

• Bulletin of the Korean Chemical Society
• /
• 제20권12호
• /
• pp.1421-1427
• /
• 1999

4-Hydroxy-4'-methoxyazobenzene and 4-hydroxy-4'-cyanoazobenzene were synthesized from phenol with p-anisidine and p-aminobenzonitrile through a diazotization reaction, respectively. They were reacted with 2-chloroethanol, 2-(2-chloroethoxy)ethanol, or 2-[2-(2-chloroethoxy)ethoxy]ethanol to produce six kinds of new mesogenic alcohols having an azobenzene group that is sensitive to the ultraviolet. Twelve kinds of new photoresponsive monomers with two symmetrical mesogens were prepared by the reaction of the mesogenic alcohols with fumaric acid or maleic acid through a Mitsunobu reaction. The resulting monomers have different length of flexible ethyleneoxy spacer tethered to azobenzene group. The length of the spacer affected their thermal stability, solubility, and phase transition temperature. Structures of the monomers were identified by FT-IR and ¹H-NMR spectra. Their phase transition temperatures and thermal stability were also investigated by a differential scanning calorimetry (DSC) and a thermogravimetric analysis (TGA). From an optical polarizing microscopy, all the prepared monomers except fumarate-1 and maleate-1 were found to show enantiotropic liquid crystallinity with a smectic texture like focal-conic, fan-shaped, and batonnet textures.

• 보존과학연구
• /
• 통권31호
• /
• pp.9-16
• /
• 2010

The Annals of the Joseon Dynasty is one of the World Heritage which should be conserved well. However, some of wax treated volume of the Annals of the Joseon Dynasty have damaged seriously. Currently a variety of efforts to conserve and restore the injured volumes are continued and many studies about the aging mechanism of the wax treated volume have being progressed. The analysis of VOCs (Volatile Organic Compounds) emitted from paper cultural heritage is one of the methods to understand the degradation pathway of paper cultural heritage. The analysis of VOCs emitted from paper cultural heritage has been mainly conducted by SPME (Solid Phase Microextraction) method. SPME is potable and simple method but it is difficult to collect all VOCs emitted from a book such as the Annals of Joseon Dynasty. The dynamic chamber system has generally used to do analysis of VOCs emitted from the building materials, furniture and electric appliances. The chamber system is possible to do quantitative and qualitative analysis by a continuous $N_2$ gas flow and the proper chamber which is able to gather all VOCs emitted from the Annals of the Joseon Dynasty. In this study, the most material among detected VOCs was Naphthalene. Naphthalene has used to prevent organic cultural heritage from being damaged by various microbes for a long time. Apart from Naphthalene, main VOCs were Acetic acid, 2-Chloroethanol, 2-Bromoethanol, Furfural, 1-Methylnaphthalene, Azulene, and 2,4-Dioctylphenol. Of these VOCs, Furfural especially was known for a marker which represents a different emission rate according to the aging level.

• 농업과학연구
• /
• 제9권2호
• /
• pp.591-595
• /
• 1982

시판중인 유기불소계 살서제인 키라톨-F 제의 화학적(化學的)특성을 알아보기 위해 본 실험을 수행하였다. 시료는 제조회사에 따라 두 종류를 비교 검토하였으며, 아울러 실험실내 합성을 통해 주성분을 확인하고자 시도하였으며 그 중요한 결과는 아래와 같다. 1. 시판 키라톨-F제의 주성분으로 제시된 ${\beta}$-fluoroethanol acetate 는 확인할 수 없었으며, 그대신 ${\beta}$-fluoroethanol 이 주성분으로 밝혀졌다. 2. 시판 키라톨-F제는 수용액이며 chloro ethanol 이 소량 함유되어 있다. 3. 실험 실내에서 합성한 fluoroethanol은 ${\alpha}$-와 ${\beta}$-fluoroethanol 의 혼합물로 추정되며 합성수율은 광조건이 암조건보다 훨씬 높은 것으로 나타났다. 4. 키라톨-F제의 희석 배율에 따른 경시변화를 조사한 결과, 주성분의 분해는 일어나지 않았으며, 따라서 2차독성의 가능성이 매우 높은 것으로 생각된다.

• 대한화학회지
• /
• 제27권6호
• /
• pp.449-456
• /
• 1983

방사선장해를 예방할 수 있는 특성을 지닌 티오인산 이수소 S-2-(${\omega}$-아미노알킬아미노)에틸들의 간편한 합성법을 연구하였다. 중간체인 3-(2-프탈이미도에틸)-2-옥사졸리디논을 프탈이미드 칼륨염과 3-(2-브로모에틸)-2-옥사졸리디논을 반응시켜 만들었으며, 이 브로모에틸의 옥사졸리디논 유도체는 디에탄올아민으로부터 만들어진 2,2-디브로모 디에틸아민과 탄산염 혼합물의 알카리성 고리닫기 반응으로 합성할 수 있었다. 이 중간체는 30% 브롬화수소(가스)-초산용액으로 반응시켜 브롬화수소 N-(2-(2-브로모에틸아미노)에틸)프탈이미드로 유도되었고 이것을 다시 브롬화수소-초산용액으로 반응시켜 이브롬화수소 N-(2-브롬화에틸)-1,2-에탄디아민을 얻을 수 있었다. 1,3-디아미노프로판과 2-클로로에탄올로부터 2-(3-아미노프로필아미노)에탄올을 합성하고 이것을 Cortese씨법으로 처리하여 이브롬화수소 N-(2-브로모에틸)-1,3-프로판아민을 얻었다. 이들 이브롬화수소들을 DMF 용매에서 티오인산 나트륨으로 처리하여 티오인산 이수소 S-2-(${\omega}$-아미노알킬아미노) 에틸들을 합성하였다. 각각의 합성과정의 특징을 반응조건 및 총수율과 관련시켜 논의하였으며 티오인산 유도체를 합성하는 각편한 방법을 제의하였다.