• 제목/요약/키워드: 2-amino-3-ethoxycarbony1-N-$\beta$-hydroxyethy1--4,9-dione

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분자내 고리화반응에 의한 -4,9-Dione 유도체 합성 (Synthesis of -4,9-Dione Derivatives via Intramolecular Cyclization)

  • 신상희;서명은
    • 약학회지
    • /
    • 제35권3호
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    • pp.231-235
    • /
    • 1991

  • Compounds of the structure of -4,9-dione are known to have an antibacterial activity against Gram-positive bacteria. New kinds of 2-amino-$\alpha$-cyano-$\alpha$-ethoxycarbonyl-niethyl)-1,4-naphthoquino ne was reacted with some alkylamines(methylamine, ethylamine, ethanolarnine, isopropylamine, cyclohexylamine, benzylamine) to yield 2-amino-3-ethoxycarbonyl-N-alkyl-4,9-diones.

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