• The Journal of Korean Institute of Communications and Information Sciences
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• v.26 no.11A
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• pp.1897-1907
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• 2001

제안된 연구는 유방촬영영상(Mammogram)에서 종양의 자동 추출에 관한 연구로서, 맘모그램에서 특성을 파악하여 종양을 추출하였다. 처리과정에서 정상조직인 cooper\`s ligament 로부터 조직의 붕괴에 의한 동질화된 종양조직을 분리하였다. 추출된 부분들을 8-연결성 관계를 이용하여 1차 후보를 추출하였다. 1타 추출긴 각 후보들을 영상의 명암값을 지형적 높이정보로 해석한 2단계의 영상으로 표현하였다. 이러한 영상에서 2 중의 원형성과 분포 비율로 비교하는 방법을 통하여 2차 후보를 추출하였다. 최종적인 종양의 결정은 각 후보에 대한 반구 형태의 템플리트를 생성하여 비교하는 방법을 통하여 순위를 결정하였다. 추출된 결과로서 진단방사선 전문의에 의해 종양의 포함이 확진된 58 사례에 적용하여 모든 사례에서 종양을 추출하였고 1 사례를 제외하고 종양을 첫 번째 순위로 검출할 수 있었다.

• 대한두경부종양학회:학술대회논문집
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• 1990.11a
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• pp.32.2-34
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• 1990

• Journal of Korea Multimedia Society
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• v.5 no.2
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• pp.141-146
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• 2002

This paper proposed the automated methods for th detection of mass. We analysed characteristic of mass by using the features on mammograms. In first step, the homogeneity was used to distinguish mass from the normal tissue. In second step, we examined the dualistic circularity and pixel distribution of candidates from the dualistic images of each candidates in which we regards the gray value as topographic height information. The final decision was done with the method in which each candidates is compared with the hemispheric template. Template matching method was used in comparing the priority of candidates with the spacial circularity which is the characteristic of the mass, We applied the algorithm to the 180 mammograms. The detection resulted that the sensitivity of the proposed methods was 95.51% in which we detected 85 from the 89 mammograms.

• Radiation Oncology Journal
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• v.24 no.2
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• pp.149-155
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• 2006

Meningeal hemangiopericytoma (HPC) is an uncommon dura-based tumor and can recur not only locally but also distantly in the neural axis or extraneural sites. We report our experience of radiation therapy, one preoperative and one elective postoperative, In two patients with meningeal HPC and reviewed the role of radiation therapy. A 41-year-old man (Case 1) presented with a 3-month history of headache and right hemiparesis. The mass was nearly unresectable at the first and second operation and diagnosed as meningeal HPC. Preoperative radiation therapy was given with a total dose of 55.8 Gy/31 fractions to the large residual mass of left frontoparietal area. Follow-up computerized tomography (CT) showed marked regression of tumor after radiation therapy. The third operation was peformed to remove the residual tumor at 6 months after the radiation therapy and a $2{\times}2cm$ sized tumor was encountered. The mass was totally removed. The serial follow-up CT showed no evidence of recurrence and he is alive without distant metastasis for 4 years and 10 months after the first operation. A 45-year-old woman (Case 2) presented with suddenly developed headache and visual impairment. Tumor mass occupying right frontal lobe was removed with the preoperative diagnosis of meningioma. It was totally removed with attached sagittal sinus and diagnosed as meningeal HPC. Elective postoperative radiation therapy was peformed to reduce local recurrence with a total dose of 54 Gy/30 fractions to the involved area of right frontal lobe. She is alive for 5 years maintaining normal activity without local recurrence and distant metastasis.

• Journal of Digestive Cancer Research
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• v.9 no.2
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• pp.71-74
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• 2021

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.38 no.6
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• pp.721-734
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• 2001

This paper proposed automated methods for the detection of breast mass. We analysed characteristic of the mass by using the features on mammograms. The homogeneity was used to distinguish mass and abnormal homogeneous tissue from the Cooper's ligament and multiple threshold method was used to deal with the high density candidates. By using the 8-connectivity, the first step candidates were selected. We generated the dualistic images of each candidate in which we regard the gray value as topographic height information. From these candidates, the second candidates were selected by comparing the circularity and the distribution rates. The final detection was done with the method in which we generated the template of each candidate and compared each other. From these methods, we grade the order from the candidate. We applied the algorithm to the 136 mammograms and compared to the radiologist's outlines of the leisions. The detection resulted that the sensitivity of the proposed methods was 93.38% and 97.63% FP(False positive) which we can segmented mass in the first grade in the 124 cases.

• Korean Journal of Head & Neck Oncology
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• v.38 no.2
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• pp.19-21
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• 2022

Pneumoparotid is a rare diagnosis to consider when faced with unexplained parotid swelling. It is caused by an excessive increase of intraoral pressure and reflux of air through the Stensen duct and its glandular branches. It is more likely to occur in persons who have regularly raised intraoral pressure, for example glass and balloon blowers and wind instrument players. It can also be self-induced by habitual tic. Herein, we report a rare case of pneumoparotid with initial presentation of painless swelling in left parotid region. It was caused by habitual cheek inflating and improved with conservative management.

• Journal of Biomedical Engineering Research
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• v.25 no.1
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• pp.49-55
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• 2004

In this paper, we investigated the effects of the photodynamic therapy(PDT) for the tumor mass in mice. In the experimental method, we divided the mice into two control and test group which HepG2 and HeLa cell line induced cancer mass in mice. Photofrin was administered to the tumor-bearing mouse, followed 30 hours later by 630nm and 650nm laser light exposure. After photodynamic therapy we analyzed the two mice group for the tumor mass size, tumor growth, tumor cell necrosis, pathological anatomy change. According to the results, tumor cell necrosis was shown in the tissues which the reduce size of tumor and tumor cell necrotic change according to the irradiation time and light dose amount. The considerable difference, however, between the 630nm and 650nm wavelength was not found for the tumor cell necrotic change and other damage of normal tissue was not found.

• Korean Journal of Head & Neck Oncology
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• v.10 no.1
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• pp.38-45
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• 1994

부인두강(Parapharyngeal space)는 비인두강과 구인두강에 인접하여 위로는 두개저, 아래로는 설골사이에 위치하는 해부학적 잠재공간으로 이곳에 발생하는 종양은 매우 드무나 다양한 병리조직학적 소견을 보이며 인접한 중요장기들로 인한 수술적 어려움으로 두경부 외과의사의 관심이 되어 왔다. 최근 CT나 MRI의 도입으로 이학적 검사가 어려웠던 이부위의 진단에 많은 도움을 얻게 되었고, 발달된 수술방법의 사용으로 크기가 매우 큰 종양도 절제가 가능하게 되었다. 저자들은 1990년 9월부터 1993년 8월까지 한림대학교 이비인후과학교실에서 술전 CT나 MRI를 시행한 후 조직검사로 확진된 부인두강 종물 22례의 후향적 임상분석을 시행하여 다음의 결과를 얻었다. 1) 양성종양이 11례(30.0%), 악성종양이 11례(50.0%)로 빈도에 차이는 없었다. 2) 종양의 조직학적 기원은 타액선종양이 10례(45.5%)로 가장 많았으며 신경종양이 4례(18.2%)였고 기타 종양이 8례(36.4%)로 다양하였다. 3) 방사선학적 진단방법으로는 18례(81.8%)에서 CT를 시행하였고 필요한 경우에 MRI를 5례(22.7%), 혈관조영술을 3례(13.6%)에서 시행하였다. 4) 치료방법으로는 악성종양은 수술 및 방사선치료 또는 항암약물요법을 병리조직검사 결과에 따라 단독 또는 병합하여 시행하였고, 양성종양의 경우에는 모두 수술을 시행하였는데 수술방법은 경이하선 접근법이 가장 많이 사용되었다. 5) 추적조사는 평균 20개월로 양성종양의 경우는 모두 종양의 재발이 없이 치료되었으나 악성종양 중 전이암 1례와 악성 임파종 1례가 사망하였다.

• Journal of Life Science
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• v.2 no.4
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• pp.240-247
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• 1992

차의 풍미의 차이는 차잎 자체가 가자고 있는 화학성분 조성의 차이와 가공방법의 차이에 기인하고, 차잎의 화학성분은 차나무의 훔종, 토질, 기후, 재배기술과 시비 등에도 영향을 받는다. 차의 특유한 맛의 주성분은 주로 카테킨과 아미노산류이다. 단맛과 감칠맛은 주로 아미노산 때문이지만 당류도 어느 정도 기여한다. 카테킨류에 의한 최근의 연구결과를 보면 노화를 방지하는 1)항산화 작용 2) 항종양, 발암 억제작용 3) 콜레스테롤 량의 조정 4)고혈압과 혈당 강하작용 5)항균작용과 해독작용이 있다.