• The Korean Journal of Nuclear Medicine Technology
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• v.14 no.2
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• pp.190-196
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• 2010

Purpose: This study was undertaken to investigate the feasibility of using automated liquid-handling systems equipped with reusable fixed tips in Radioimmunoassays and to demonstrate that the use of an automated pipetting instrument can decrease in the typical daily workload. Materials and Methods: The precisions of the automated pipettor and the manual pipettor were determined gravimetrically (n=30). A total of 30 specimens for HBs Ag were repeatedly pipetted (three replicates) with the automated pipettor and then retested. PSA samples were simultaneously pipetted with either the automated pipettor or the manual pipettor and then analyzed (n=40). Sample carryover test assessed for CA19-9, AFP and HCG when the automated pipettor was used. Pipetting speed of the automated pipettor and the manual pipettor were compared by evaluation of each workload. Results: The precisions coefficients of variation (CV) were 2.1% for the automated pipettor and 1.6% for manual pipettor. The mean cpm and CV for each group of replicates were 41,203 cpm and 3.7% for HBs Ag positive specimens, and 99 cpm and 7.9% for HBs Ag negative specimens, respectively. PSA results showed no significant differences between automated pipettor and manual pipettor (p=0.15, r=0.999). Carryover for CA19-9, AFP and HCG analytes was <0.1 ppm or below the assay limit of detection. Pipetting speed was significantly improved by using the automated instrument. Conclusion: There was no evidence that the use of an automated pipettor adversely affected any of the performance characteristics of the assay. Indeed, routine use of the Tecan automated pipettor has resulted in a decrease in the typical daily workload.

• Progress in Medical Physics
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• v.13 no.3
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• pp.149-155
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• 2002

Recent advances in radiation transport algorithms, computer hardware performance, and parallel computing make the clinical use of Monte Carlo based dose calculations possible. To compare the speed and accuracies of dose calculations between different developed codes, a benchmark tests were proposed at the XIIth ICCR (International Conference on the use of Computers in Radiation Therapy, Heidelberg, Germany 2000). A Monte Carlo treatment planning comprised of 28 various Intel Pentium CPUs was implemented for routine clinical use. The purpose of this study was to evaluate the performance of our system using the above benchmark tests. The benchmark procedures are comprised of three parts. a) speed of photon beams dose calculation inside a given phantom of 30.5 cm$\times$39.5 cm $\times$ 30 cm deep and filled with 5 ㎣ voxels within 2% statistical uncertainty. b) speed of electron beams dose calculation inside the same phantom as that of the photon beams. c) accuracy of photon and electron beam calculation inside heterogeneous slab phantom compared with the reference results of EGS4/PRESTA calculation. As results of the speed benchmark tests, it took 5.5 minutes to achieve less than 2% statistical uncertainty for 18 MV photon beams. Though the net calculation for electron beams was an order of faster than the photon beam, the overall calculation time was similar to that of photon beam case due to the overhead time to maintain parallel processing. Since our Monte Carlo code is EGSnrc, which is an improved version of EGS4, the accuracy tests of our system showed, as expected, very good agreement with the reference data. In conclusion, our Monte Carlo treatment planning system shows clinically meaningful results. Though other more efficient codes are developed such like MCDOSE and VMC＋＋, BEAMnrc based on EGSnrc code system may be used for routine clinical Monte Carlo treatment planning in conjunction with clustering technique.

• Asian Journal of Turfgrass Science
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• v.23 no.1
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• pp.77-90
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• 2009

Near Infrared Reflectance Spectroscopy(NIRS) is a quick, accurate, and non-destructive method to measure multiple nutrient components in plant leaves. This study was to acquire a liner regression equation by evaluating the nutrient contents of 'CY2' creeping bentgrass rapidly and accurately using NIRS. In particular, nitrogen fertility is a primary element to keep maintaining good quality of turfgrass. Nitrogen, moisture, carbohydrate, and starch were assessed and analyzed from 'CY2' creeping bentgrass clippings. A linear regression equation was obtained from accessing NIRS values from NIR spectrophotometer(NIR system, Model XDS, XM-1100 series, FOSS, Sweden) programmed with WinISI III project manager v1.50e and ISIscan(R) (Infrasoft International) and calibrated with laboratory values via chemical analysis from an authorized institute. The equation was formulated as MPLS(modified partial least squares) analyzing laboratory values and mathematically pre-treated spectra. The accuracy of the acquired equation was confirmed with SEP(standard error of prediction), which indicated as correlation coefficient($r^2$) and prediction error of sample unacquainted, followed by the verification of model equation of real values and these monitoring results. As results of monitoring, $r^2$ of nitrogen, moisture, and carbohydrate in 'CY2' creeping bentgrass was 0.840, 0.904, and 0.944, respectively. SEP was 0.066, 1.868, and 0.601, respectively. After outlier treatment, $r^2$ was 0.892, 0.925, and 0.971, while SEP was 0.052, 1.577, and 0.394, respectively, which totally showed a high correlation. However, $r^2$ of starch was 0.464, which appeared a low correlation. Thereof, the verified equation appearing higher $r^2$ of nitrogen, moisture, and carbohydrate showed its higher accuracy of prediction model, which finally could be put into practical use for turf management system.

• Korean Journal of Food Science and Technology
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• v.30 no.2
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• pp.341-347
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• 1998

To develop simple and accurate analytical method for freezing time prediction of beef and tylose under various freezing conditions, freezing time (Y) was regressed against the reciprocal $(X_3)$ of difference of initial freezing point and freezing medium temperature, reciprocal $(X_4)$ of surface heat transfer coefficient, the initial temperature $(X_1)$ and thickness $(X_2)$ of samples which should cover most situations arising in frozen food industry. As results of the multiple regression analysis, equations were obtained as follows. $Y_{tylose}=3.45X_1+7642.84X_2+4642.67X_3+2946.89X_4-431.33\;(R^2=0.9568)$ and $Y_{beef}=0.68X_1+7568.98X_2+2430.78X_3+3293.26X_4-299.00\;(R^2=0.9897)$. These equations offered better results than Plank, Nagaoka and Pham's models, shown in satisfactory agreement with models of Cleland & Earle and Hung & Thompson when were compared to previous models, and the accuracy of its was very high as average absolute difference of about 10% in the difference between the fitted and experimental results. Also, thermal diffusivities of beef and tylose were measured as $4.43{\times}10^{-4}m^2/hr$ and $4.39{\times}10^{-4}m^2/hr$ at $6{\sim}7^{\circ}C$, $2.42{\times}10^{-3}m^2/hr$ and $3.32{\times}10^{-3}m^2/hr$ at $-10{\sim}-12^{\circ}C$. Initial freezing points of beef and tylose were $-1.2^{\circ}C\;and\;-0.6^{\circ}C$, respectively. Surface heat transfer coefficients were estimated $20.57\;W/m^2^{\circ}C$ with no-packing, $16.11\;W/m^2^{\circ}C$ with wrap packing and $13.07\;W/m^2^{\circ}C$ with Al-foil packing, and the cooling rate of immersion freezing method was about 10 times faster than that of air blast freezing method.

• Fire Science and Engineering
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• v.32 no.1
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• pp.7-15
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• 2018

The prediction performance of combustion models in the Fire Dynamics Simulator (FDS) were evaluated by comparing with experiment for compartment propane gas fires. The mixture fraction model in the FDS v5.5.3 and Eddy Dissipation Concept (EDC) model in the FDS v6.6.3 were adopted in the simulations. Four chemical reaction mechanisms, such as 1-step Mixing Controlled, 2-step Mixing Controlled, 3-step Mixing Controlled and 3-step Mixed (Mixing Controlled + finite chemical reactions) reactions, were implemented in the EDC model. The simulation results with each combustion model showed similar level for the temperature inside the compartment. The prediction performance of FDS with each combustion model showed significant differences for the CO concentration while no distinguished differences were identified for the $O_2$ and $CO_2$ concentrations. The EDC 3-step Mixing Controlled largely over-predicted the CO concentration obtained by experiment and the mixture fraction model under-predicted the experiment slightly. The EDC 3-step Mixed showed the best prediction performance for the CO concentration and the EDC 2-step Mixing Controlled also predicted the CO concentration reasonably. The EDC 1-step Mixing Controlled significantly under-predict the experimental CO concentration when the previously suggested CO yield was adopted. The FDS simulation with the EDC 1-step Mixing Controlled showed difficulties in predicting the $CO_2$ concentration when the CO yield was modified to predict the CO concentration reasonably.

• Korean Journal of Remote Sensing
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• v.37 no.5_1
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• pp.1029-1042
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• 2021

As part of the next-generation Compact Advanced Satellite 500 (CAS500) project, CAS500-4 is scheduled to be launched in 2025 focusing on the remote sensing of agriculture and forestry. To obtain quantitative information on vegetation from satellite images, it is necessary to acquire surface reflectance through atmospheric correction. Thus, it is essential to develop an atmospheric correction method suitable for CAS500-4. Since the absorption and scattering characteristics in the atmosphere vary depending on the wavelength, it is needed to analyze the sensitivity of atmospheric correction parameters such as aerosol optical depth (AOD) and water vapor (WV) considering the wavelengths of CAS500-4. In addition, as CAS500-4 has only five channels (blue, green, red, red edge, and near-infrared), making it difficult to directly calculate key parameters for atmospheric correction, external parameter data should be used. Therefore, thisstudy performed a sensitivity analysis of the key parameters (AOD, WV, and O₃) using the simulated images based on Sentinel-2 satellite data, which has similar wavelength specifications to CAS500-4, and examined the possibility of using the products of GEO-KOMPSAT-2A (GK2A) as atmospheric parameters. The sensitivity analysisshowed that AOD wasthe most important parameter with greater sensitivity in visible channels than in the near-infrared region. In particular, since AOD change of 20% causes about a 100% error rate in the blue channel surface reflectance in forests, a highly reliable AOD is needed to obtain accurate surface reflectance. The atmospherically corrected surface reflectance based on the GK2A AOD and WV was compared with the Sentinel-2 L2A reflectance data through the separability index of the known land cover pixels. The result showed that two corrected surface reflectance had similar Seperability index (SI) values, the atmospheric corrected surface reflectance based on the GK2A AOD showed higher SI than the Sentinel-2 L2A reflectance data in short-wavelength channels. Thus, it is judged that the parameters provided by GK2A can be fully utilized for atmospheric correction of the CAS500-4. The research findings will provide a basis for atmospheric correction of the CAS500-4 in the future.

• Journal of Environmental Impact Assessment
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• v.26 no.2
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• pp.114-126
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• 2017

Many studies on climate change and its impacts use a single climate scenario. However, one climate scenario may not accurately predict the potential impacts of climate change. We estimated temperature and precipitation changes by 2070 using 17 of the CMIP5 Global Climate Models (GCMs) and two emission scenarios for three spatial domains: the Asian continent, six East Asia countries, and South Korea. For South Korea, the range of increased minimum temperature was lower than for the ranges of the larger regions, but the range of projected future precipitation was higher. The range of increased minimum temperatures was between $1.3^{\circ}C$ and $5.2^{\circ}C$, and the change in precipitation ranged from - 42.4 mm (- 3.2%) and + 389.8 mm (+ 29.6%) for South Korea. The range of increased minimum temperatures was between $2.3^{\circ}C$ and $8.5^{\circ}C$ for East Asia countries and was between $2.1^{\circ}C$ and $7.4^{\circ}C$ for the Asian continent, and the change in precipitation ranged from 28.8 mm (+ 6.3%) and 156.8 mm (+ 34.3%) for East Asia countries and from 32.4 mm (+ 5.5%) and 126.2 mm (+ 21.3%) for the Asian continent. We suggest climate change studies in South Korea should not use a single GCM or only an ensemble climate model's output and we recommend to use GFDL-CM3 and INMCM4 GCMs to bracket projected change for use in other national climate change studies to represent the range of projected future climate conditions.

• Proceedings of the Korean Nuclear Society Conference
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• 1996.05b
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• pp.473-480
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• 1996

영광 3/4호기 mid-loop 운전중 잔열제거(RHR) 기능 상실사고시 열수력적 현상을 최적 전산코드인 CATHARE2를 이용하여 해석하였다. 이러한 사고시 열수력적 현상은 일,이차측 냉각재 방출유로와 계통내 비응축성 가스의 거동에 의해 크게 영향을 받는다. 본 연구에서는 2개의 경우를 모의하였는데, 하나는 계통내 방출유로가 있는 경우이며 다른 하나는 방출유로가 없는 경우를 계산하였다. 이 때 사용된 가정은 다음과 같다. (가) 계통은 부분충수 운전 상태로 상부에 비응축성 가스나 증기로 가득 차 있다. (나) 증기발생기는 1대만이 이용 가능하고 이차측은 습식보관 상태이며, 보조급수는 공급되지 않고 이차측 압력은 대기압 상태이다 (다) 사고는 원자로 정지후 2일후 발생한다. 이와같은 조건하에서 사고시 계통 최대압력은 방출유로가 있는 경우 사고후 6,000 초에 0.27 MPa이며, 방출유로를 통한 유량은 총 2.4 kg/s이다. 이 방출유량을 외삽하여 계통수위가 고온관 바닦까지 도달하는데 걸린 시간은 사고후 약 5.67시간이다. 증기발생기 U-튜브를 통한 열전달에 의해 이차측 증기 발생으로 이차측 수위가 하락하면 증기발생기 reflux cooling은 제한을 받을 수 있다. 이 경우 이차측 수위가 U-튜브의 active 영역 상부까지 도달하는데 걸리는 시간은 사고후 약 10시간으로 계산되었다. 그러므로 이 경우 보조급수 공급 여유시간보다 노심 노출시간이 더 빨리 도달하여 노심을 손상시킨다. 사고시 수위지시계는 계통감압에 큰 영향을 주지 못하기 때문에 가능한 빨리 닫아 계통 inventory를 유지하는 것이 이차측 보조급수공급보다 우선한다.합한 설계방안으로 분석되었다.크다는 단점이 있다.TEX>$_2$O$_3$ 흡착제 제조시 TiO$_2$ 함량에 따른 Co$^{2＋}$ 흡착량과 25$0^{\circ}C$의 고온에서 ZrO$_2$와 $Al_2$O$_3$의 표면에 생성된 코발트 화합물을 XPS와 EPMA로 부터 확인하였다.인을 명시적으로 설명할 수 있다. 둘째, 오류의 시발점을 정확히 포착하여 동기가 분명한 수정대책을 강구할 수 있다. 셋째, 음운 과 정의 분석 모델은 새로운 언어 학습시에 관련된 언어 상호간의 구조적 마찰을 설명해 줄 수 있다. 넷째, 불규칙적이며 종잡기 힘들고 단편적인 것으로만 보이던 중간언어도 일정한 체계 속에서 변화한다는 사실을 알 수 있다. 다섯째, 종전의 오류 분석에서는 지나치게 모국어의 영향만 강조하고 다른 요인들에 대해서는 다분히 추상적인 언급으로 끝났지만 이 분석을 통 해서 배경어, 목표어, 특히 중간규칙의 역할이 괄목할 만한 것임을 가시적으로 관찰할 수 있 다. 이와 같은 오류분석 방법은 학습자의 모국어 및 관련 외국어의 음운규칙만 알면 어느 학습대상 외국어에라도 적용할 수 있는 보편성을 지니는 것으로 사료된다.없다. 그렇다면 겹의문사를 [-wh]의리를 지 닌 의문사의 병렬로 분석할 수 없다. 예를 들어 누구누구를 [주구-이-ν가] [누구누구-이- ν가]로부터 생성되었다고 볼 수 없다. 그러므로 [-wh] 겹의문사는 복수 의미를 지닐 수 없 다. 그러면 단수 의미는 어떻게 생성되는가\

• Proceedings of the Korean Vacuum Society Conference
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• 1999.07a
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• pp.54-54
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• 1999

다이아몬드 합성시 질소 첨가는 Cn 화합물의 합성가능성을 비롯하여 다이아몬드의 질소 도핑, 성장 속도 및 결정성 변화 등 다양한 관점에서 중요한 의미를 가지고 있다. 본 연구에서는 다이아몬드의 일반적인 합성조건에서 질소를 첨가하여 합성된 막의 형상 및 상 변화에 대해 고찰하였다. 막은 다이아몬드 전처리시킨 Si 기판위에 microwave plasma CVD 장치를 이용하여 합성하였다. 유입되는 혼합가스(CH4+H2+N2)에서 N2 첨가량을 0-95%까지 변화시켰다. 이때 CH4 농도는 5%로 고정하였고, 합성온도는 90$0^{\circ}C$-115$0^{\circ}C$까지 변화시켰다. 이와 같이 합성된 막의 표면조직 및 성장 두께를 측정하기 위해 주사전자현미경을 이용하였다. 상의 분석은 Raman, XRD 및 TEM 분석을 이용하였으며, 조성분석을 위해 XPS 및 AES를 사용하였다. 질소 첨가량에 따라 합성된 막은 첨가하지 않은 경우에 다이아몬드 결정에서 시작하여 질소첨가에 따라 결정면이 깨지는 것으로 나타났다. 그러나 30%, 45%의 경우는 다시 결정면이 나타났다. 다량의 질소가 첨가되었을 때, 다시 결정면을 보이는 다이아몬드가 합성된 것은 매우 흥미로운 결과이다. 한편 질소와 메탄만의 기체하에서는 다시 결정면이 관찰되지 않았다. 이들 상의 구조는 XRD 및 TED 분석을 통해 모두 다이아몬드로 확인되었다. 기체내의 질소의 첨가에 관계없이 고상내에 질소는 확인되지 않았다. 따라서 이방법에 의한 CN 화합물의 합성은 힘든 것으로 보여진다. 이들 실험 결과를 근거로 온도 및 조성에 따른 기체의 열역학적 계산을 통하여 합성거동과의 연관성을 검토하였다. anode는 매우 높은 충전용량을 갖는데 첫 번째 방전시에 Li2O를 생성하여 비가역적 반응을 나타내고 계속되는 충방전 동안 Li-Sn 합금이 생성되어 2차전지의 가역적 반응을 가능하게 한다. SnO2 는 대기중에서 Li 금속보다 안정하기 때문에 전지의 제작 공정 및 사용 면에서 매우 우수한 물질이지만 아직까지 SnO2 구조적 특성과 전지의 충, 방전 특성에 대한 관계의 규명을 위한 정확한 정설은 제시되고 있지 못하다. 본 연구에서는 TFSB anode 물질로써 SnOx박막을 상온에서 여러 전도성 콜렉터 위에 증착하여 그 충, 방전 특성을 보고하였다. 증착된 SnOx박막의 표면은 SEM, AFM으로 분석하였으며 구조의 분석은 XR와 Auger electron spectroscope로 하였다. 충, 방전 특성을 분석하기 위하여 리늄 foil을 대극과 참조 전극으로 하여 EC:DMC=1:1, 1M LiPF6 액체 전해질을 사용한 Half-Cell를 구성하여 100회 이상의 정전류 충, 방전 시험을 행하였다. Half-Cell test 결과 박막의 구조, 콜렉터의 종류 및 Sn/O비에 따라 서로 다른 충, 방전 거동을 나타내었다.다. 거의 없었다. 5mTorr 일 때가 가장 좋았다.수 있음을 알 수 있었다. 그러므로, RNA바이러스의 하나인 BVDV의 viral replicon을 이용하여 다양한 종류의 포유동물 세포에 유전자 발현벡터로써 사용할 수 있음으로 post-genomics시대에 다양한 종류의 단백질 기능연구에 맡은 도움이 되리라 기대한다.다양한 기능을 가진 신소재 제조에 있다. 또한 경제적인 측면에서도 고부가 가치의 제품 개발에 따른 새로운 수요 창출과 수익률 향상, 기존의 기능성 안료를 나노(na

• Clinical and Experimental Pediatrics
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• v.51 no.5
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• pp.506-511
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• 2008

Purpose : The results of pulmonary function test (PFT) in children are variable according to the patient's cooperation and comprehensiveness. This study has intended to figure out the effectiveness of pre-education and training with balloons on PFT in children. Methods : One hundred six children mean aged $9.35{\pm}2.92\;years$ were tested. All participants performed PFT twice in 30 minutes intervals. First PFT were performed after usual instruction and second PFT were performed according to randomly classified grouping; Group 1 : repeat PFT after training with balloons, Group 2 : repeat PFT after training and education, both, Group 3 : repeat PFT after education about objects and necessities of pulmonary function test, Group 4 : repeat PFT without any education and training. Results : There were no difference statistically on the results of percent of predicted $FEV_1$, $FEV_1/FVC$, $FEF_{25-75%}$ and PEFR in Group 1, 2 and 4 patients. In some cases, the average is decreased with repeated PFT. At the case of repeated PFT after education, the average of percent of predicted $FEV_1$, $FEV_1/FVC$, $FEF_{25-75%}$ and PEFR is increased. There was statistically significant difference on the value of $FEV_1$, $FEF_{25-75%}$ and PEFR between first and second PFT in Group 3. Conclusion : Training with balloons before PFT causes fatigueness and lowers concentration. Understanding of PFT makes results better than training. Therefore, enough explanation and education about PFT before examination is most effective for appropriate PFT in children.