• Journal of Physiology & Pathology in Korean Medicine
• /
• v.26 no.1
• /
• pp.88-97
• /
• 2012

DSOM(Diagnosis System of Oriental Medicine), questionnaire for oriental medical(medicine) diagnosis is an online survey system containing 152 questions for female, 149 questions for male that asking the basic symtoms of 16 pathogenic factors(病機). The result of DSOM denotes reliability according to the level of major symptoms of each pathogenic factor. Standard level of reliability is equal to all 16 pathogenic factor basically except phlegm(痰). In case of phlegm(痰) we give different weight depending on whether the factor includes gray color under the orbit(痰飮氣) or not. To examine reliability of DSOM, statistical analysis has been done to the data of felmale 10101, male 1564 except for bad responses and stored between 1st April 2000 to 3rd June 2011. Based on the study, the conclusions were as follows. Reliability of DSOM. For female, all pathogenic factors showed over 85% confidence level except for phlegm 82.6%. For male, all pathogenic factors showed more than 90% confidence level except two factors, phlegm(痰) indicates 87.% and damp(濕) indicates 89.8%. HH rates among pathogenic factors were more than 50 points. For female, HH rates of other 14 pathogenic factors were all over 80% except for heat(熱) 78.2% and insufficiency of Yang(陽虛) 75.3%. For male HH rates of all pathogenic factors were more than 80% except HH rates of heat 78.2% and damp 77.8%. Research based on a degree of satisfaction of reliability derived from pathogenic factors with scores of HH results in for all 16 pathogenic factors showed over 85% of relatively high level of satisfaction for both sexes whose reliability standard come under 5~4 points. Comparing appearance frequency of pathogenic factors for both sexes. Male only displays higer than female in heat(熱). Whereas female were higher than male for other 15 pathogenic factors and the difference was biggest in heart(心) and least in insufficiency of Yin(陰虛). Comparing appearance frequency order of pathogenic factors for both sexes. Female outdistanced male in blood stasis(血瘀) coldness(寒) blood-deficiency(血虛) phlegm(痰), while male outdistance female in heat(熱) insufficiency of Yin(陰虛) deficiency of qi(氣虛). Male had lower average of each pathogenic factors than female except heat(熱) as well as deficiency of qi(氣虛).

• Genomics & Informatics
• /
• v.4 no.1
• /
• pp.1-10
• /
• 2006

Epigenetic alterations are common features of human solid tumors, though global DNA methylation has been difficult to assess. Restriction Landmark Genomic Scanning (RLGS) is one of technology to examine epigenetic alterations at several thousand Notl sites of promoter regions in tumor genome. To assess sequence information for Notl sequences in RLGS gel, we cloned 1,161 unique Notl-linked clones, compromising about 60% of the spots in the soluble region of RLGS profile, and performed BLAT searches on the UCSC genome server, May 2004 Freeze. 1,023 (88%) unique sequences were matched to the CpG islands of human genome showing a large bias of RLGS toward identifying potential genes or CpG islands. The cloned Notl-loci had a high frequency (71%) of occurrence within CpG islands near the 5' ends of known genes rather than within CpG islands near the 3' ends or intragenic regions, making RLGS a potent tool for the identification of gene-associated methylation events. By mixing RLGS gels with all Notl-linked clones, we addressed 151 Notl sequences onto a standard RLGS gel and compared them with previous reports from several types of tumors. We hope our sequence information will be useful to identify novel epigenetic targets in any types of tumor genome.

• Journal of the Korea institute for structural maintenance and inspection
• /
• v.17 no.3
• /
• pp.56-64
• /
• 2013

The wind resistant capacity of bridges with a span of less than 200m is typically evaluated by Wind Resistant Design Manual for Highway Bridges in Japan. Also, the first vertical frequency plays an important role in the evaluation of their aerodynamic performance. An unexpected vortex-induced vibration of Nielsen arch bridge with span of 183m designed by this manual has been measured by monitoring system during typhoon. The amplitude of vibrations was about 2 times than the allowable vibration displacement. This paper presents the feature of vortex-induced vibration of this Nielsen arch bridge based on measured wind velocity, wind direction, and responses at midspan of main girder. From the result of FFT, the $1^{st}$ mode shape of the bridge is antisymmetric and the $2^{nd}$ is symmetric. Also, the dominant vibration of the bridge is the $2^{nd}$ vertical mode. According to these results, the $2^{nd}$ vertical vibration mode of this Nielsen arch bridge is prior to the first for the estimation of wind resistance capacity.

• Archives of Reconstructive Microsurgery
• /
• v.5 no.1
• /
• pp.70-79
• /
• 1996

From January 1980 to May 1995, ninety-six patients had been treated by free-flap transfer for the soft tissue defects of the extremities. Ninety-eight cases of free-tissue transfer were reviewed to evaluate the clinical reliability in terms of survival and quality of long-time function after reconstructive surgery. Among these 98 cases(27 cases in latissimus dorsi myocutaneous flap, 25 in dorsalis pedis flap, 20 in forearm fasciocutaneous flap, 9 in groin flap, 7 in gracilis myocutaneous flap, 6 in 1st web space flap of foot and 4 cases in tensor fascia lata flap), 92 cases of then were survived. 7 cases were performed with vein grafts. We ananalyzed the reconstruction of the extremities on 98 cases with the soft tissue defects which had been reconstructed free-flap transfer and followed for minimum 1 year period at Korea University Hospital. 1. 92 cases(93.9%) of the total 98 cases were successful and can be obtained the excellent results in soft tissue free-flap transfer. 2. While there were no clinically significant differences in survival rate of flaps transferred from different potential flap donor sites,3 cases of 9 groin flaps were showed higher failure rate due to the complications such as arterial thrombosis, infection and anatomical variation of vessels. 3. Postoperative thrombectomy was performed in 30 cases to be occured in the arterial and venous thrombosis. The revision was failed in 2 cases due to persistent arterial thrombosis and infection, then treated with skin graft. 4. Vein graft was frequently required in severely compromised-soft tissue defects resulted from high-energy trauma. The vein graft was not stitistically significant on the frequency of flap failure rate(P<0.04). 5. Meticulous monitoring, careful planning, early revision and technical considerations will provide for a high clinical success of the free-flap transfer.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.10 no.1
• /
• pp.19-24
• /
• 2009

Structural Dynamics Modification (SDM) is a very effective technique to improve structure's dynamic characteristics by adding or removing auxiliary structures, changing material properties and shape of structure. Among those of SDM technique, the method to change shape of structure has been mostly relied on engineer's experience and trial-and-error process which are very time consuming. In order to develop a systematic method to change structure shape, surface grooving technique is studied and successfully applied to HDD cover model. To verify Surface Grooving Technique, fully embossed HDD cover model was optimized. And comparing with previous optimization result, the effectiveness of this surface grooving technique was checked. The shape of groove and 1 st natural frequency were converged to the same result of previous optimization.

• Journal of Magnetics
• /
• v.17 no.2
• /
• pp.86-95
• /
• 2012

This study investigated the effects of adding a third alloying element, Ni, to create $Fe_{70-x}Pd_{30}Ni_x$ (x = 2, 4, 6, 8 at.% Ni) ferromagnetic shape memory alloys (FSMAs). The Ni replaced a portion of the Fe. The $Fe_{70-x}Pd_{30}Ni_x$ alloys were homogenized through hot and cold forging to gain a ~38% reduction in thickness, next they were solution-treated (ST) with annealing recrystallization at $1100^{\circ}C$ for 8 h and quenched in ice brine, and then aged at $500^{\circ}C$ for 100 h. Investigation of the microstructures and magnetostriction indicated that the greater Ni amount in the $Fe_{70-x}Pd_{30}Ni_x$ alloys reduced saturation magnetostriction at room temperature (RT). It was also observed that it was more difficult to generate annealed recrystallization. However, with greater Ni addition into the $Fe_{70-x}Pd_{30}Ni_x$ (x = 6, 8 at.% Ni) alloys, the $L1_0+L1_m$ twin phase decomposition into stoichiometric $L1_0+L1_m+{\alpha}_{bct}$ structures was suppressed after the $500^{\circ}C$/100 h aging treatment. The result was that the $Fe_{70-x}Pd_{30}Ni_x$ (x = 6, 8 at.% Ni) alloys maintained a high magnetostriction and magnetostrictive susceptibility (${\Delta}{\lambda}{_\parallel}{^s}/{\Delta}H$) after the alloys were aged at $500^{\circ}C$ for 100 h. This magnetic property of the $Fe_{70-x}Pd_{30}Ni_x$ (x = 6, 8 at.% Ni) alloys make it suitable for application in a high temperature (T > $500^{\circ}C$) and high frequency environments.

• Women's Health Nursing
• /
• v.1 no.1
• /
• pp.44-67
• /
• 1995

The problem related to sex is closely connected with human life. It is important to acquire accurate sexual knowledge and desirable attitude specially during adolescence, in the physical, psychological and emotional changing period. This study was made to find out the high school girls' knowledge, attitude and experience related to sex, and to support the progress of sex education at school in the future. The design was nonequivalent control pretest-posttest in the quasi-experimental design. In current study, the subjects were 102 girls from the 1 st grade of girls' commercial high school. It was control group 54 and experimental group 48. To teach the experimental group, the sex education program was combined the sex education program made in Korea Education Development Institute, Information of sex education by the Ministry of Education, other concerning articles and previous studies. The research tool was a questionnaire based on the literature review. The pretest-posttest was given to the two groups. The sex education had been taken for the experimental group but not been taken for the control group. The data was collected from May 22, 1993 to July 20, 1993 and was analyzed through spss $^{pc}$. The frequency, $x^2$-test and t-test were calculated. Summarized findings from the study are as follows : groups before sex education. 1. Regarding the first hypothesis was supported as following : "The scores of sexual knowledge in the experimental group who was given sex education will be higher than those of the control group who was not given." (t=-14.11, p=.000) 2. Regarding the second hypothesis was supported as following : "The scores of the attitude toward sex in the experimental group who given sex education will be higher than those of the control group who was not given." (t=-6.15, p=.000) The result of this study suggests that it is so necessary that school nurses should teach about sex regularly at school.

• The Korean Journal of Rehabilitation Nursing
• /
• v.6 no.1
• /
• pp.90-103
• /
• 2003

Pain management is a major issue in caring of cancer patients. Because pain management cancer patient of does not control effectively, it is important to educate reporting pain and using analgesics for having cancer patient's concerns and anxiety. The purpose of this study was to identify the effect of cancer pain management education on the pain and concerns of pain management in cancer patients. This study was a quasi-experimental as nonequivalent control pretest-post test design. The subjects of this study consisted of 50 (experimental group 25, control group 25) patients hospitalized in K university hospital in Busan. The data were collected from December 1, 2001 to April 12, 2002. The measurement tool for the concerns of pain management had used questionnaires interpretated by Kim(1999) developed by based Ward(1993) and pain nominal scale. The collected data were analyzed frequency, percentage, mean, SD, $X^2$-test, t-test, ANCOVA. The results of this study were as follows: 1. The 1st hypothesis : "The experimental group which had received the cancer pain management education were lower than the control group in the score of pain" was not supported (p>0.05). 2. The 2nd hypothesis : "The experimental group which had received the cancer pain management education were lower than the control group in concerns of pain management" was supported (F=5.285, p<0.01). In conclusion, the cancer pain management education can know what was effective to decrease in the concerns of pain management in cancer patients. Therefore, Pain Management Education must be positively utilized in clinical situation.

• Genomics & Informatics
• /
• v.13 no.4
• /
• pp.137-145
• /
• 2015

Selective sweep can cause genetic differentiation across populations, which allows for the identification of possible causative regions/genes underlying important traits. The pig has experienced a long history of allele frequency changes through artificial selection in the domestication process. We obtained an average of 329,482,871 sequence reads for 24 pigs from three pig breeds: Yorkshire (n = 5), Landrace (n = 13), and Duroc (n = 6). An average read depth of 11.7 was obtained using whole-genome resequencing on an Illumina HiSeq2000 platform. In this study, cross-population extended haplotype homozygosity and cross-population composite likelihood ratio tests were implemented to detect genes experiencing positive selection for the genome-wide resequencing data generated from three commercial pig breeds. In our results, 26, 7, and 14 genes from Yorkshire, Landrace, and Duroc, respectively were detected by two kinds of statistical tests. Significant evidence for positive selection was identified on genes ST6GALNAC2 and EPHX1 in Yorkshire, PARK2 in Landrace, and BMP6, SLA-DQA1, and PRKG1 in Duroc. These genes are reportedly relevant to lactation, reproduction, meat quality, and growth traits. To understand how these single nucleotide polymorphisms (SNPs) related positive selection affect protein function, we analyzed the effect of non-synonymous SNPs. Three SNPs (rs324509622, rs80931851, and rs80937718) in the SLA-DQA1 gene were significant in the enrichment tests, indicating strong evidence for positive selection in Duroc. Our analyses identified genes under positive selection for lactation, reproduction, and meat-quality and growth traits in Yorkshire, Landrace, and Duroc, respectively.

• Journal of Digital Convergence
• /
• v.16 no.1
• /
• pp.207-215
• /
• 2018

The purpose of this study is to investigate the relationship of job stress and job satisfaction according to leisure activity type of nurses. The subjects were from August 1, 2017 to August 15, 2017 for nurses working in general hospitals in B, K city. Data were analyzed by frequency, percentage, mean and standard deviation, t-test, ANOVA, and Pearson's Correlation coefficient. Job stress was slightly lower than the middle level and job satisfaction was slightly higher than the middle level. Job stress was negative correlated with the number of leisure activities per week in types of leisure activity, and job satisfaction was not related. In conclusion, in order to reduce job stress of nurses, it is necessary to increase the number of leisure activities per week and further study is needed for various nurses in a wide area.