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Analysis of Subjectivity on Good Universities of Science and Engineering Graduates (이공계 졸업생의 좋은 대학에 대한 주관적 인식 유형 분석)

  • Hong, Seongyoun
    • The Journal of the Korea Contents Association
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    • v.22 no.4
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    • pp.445-457
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    • 2022
  • The purposes of this research are to identify the subjective perception type of science and engineering graduates about good university and to analyze the differences of their undergraduates' experiences among types. Using Q methodology, 29 statements about a good university, reflecting on the previous research as well as quality assurance criteria in higher education, were administered to 16 science and engineering graduates for ranking using a Q-sort procedure. As a result 16 graduates were classified into three types according to their preference for 29 statements. Type 1, oriented student experience, recognized that a good university encourages students to participate in various activities and experiences. Type 2, oriented institutional outcomes, recognized that a good university is ranked high in criteria such as employment rate, research outcome, and entrance exam scores etc. Type 3, oriented educational activity, recognized that a good university is regarded as a community focusing on teaching and learning. Finally, considering the finding of the research, some pedagogical and administrational implications were suggested for quality improvement in higher education.

Application of array comparative genomic hybridization in Korean children under 6 years old with global developmental delay

  • Lee, Kyung Yeon;Shin, Eunsim
    • Clinical and Experimental Pediatrics
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    • v.60 no.9
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    • pp.282-289
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    • 2017
  • Purpose: Recent advancements in molecular techniques have greatly contributed to the discovery of genetic causes of unexplained developmental delay. Here, we describe the results of array comparative genomic hybridization (CGH) and the clinical features of 27 patients with global developmental delay. Methods: We included 27 children who fulfilled the following criteria: Korean children under 6 years with global developmental delay; children who had at least one or more physical or neurological problem other than global developmental delay; and patients in whom both array CGH and G-banded karyotyping tests were performed. Results: Fifteen male and 12 female patients with a mean age of $29.3{\pm}17.6months$ were included. The most common physical and neurological abnormalities were facial dysmorphism (n=16), epilepsy (n=7), and hypotonia (n=7). Pathogenic copy number variation results were observed in 4 patients (14.8%): 18.73 Mb dup(2)(p24.2p25.3) and 1.62 Mb del(20p13) (patient 1); 22.31 Mb dup(2) (p22.3p25.1) and 4.01 Mb dup(2)(p21p22.1) (patient 2); 12.08 Mb del(4)(q22.1q24) (patient 3); and 1.19 Mb del(1)(q21.1) (patient 4). One patient (3.7%) displayed a variant of uncertain significance. Four patients (14.8%) displayed discordance between G-banded karyotyping and array CGH results. Among patients with normal array CGH results, 4 (16%) revealed brain anomalies such as schizencephaly and hydranencephaly. One patient was diagnosed with Rett syndrome and one with $M{\ddot{o}}bius$ syndrome. Conclusion: As chromosomal microarray can elucidate the cause of previously unexplained developmental delay, it should be considered as a first-tier cytogenetic diagnostic test for children with unexplained developmental delay.

Comparison of Mass and Nutrient Dynamics of Coarse Woody Debris between Quercus serrata and Q. variabilis Stands in Yangpyeong

  • Kim, RaeHyun;Son, Yowhan;Hwang, Jaehong
    • The Korean Journal of Ecology
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    • v.27 no.2
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    • pp.115-120
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    • 2004
  • Coarse woody debris (CWD, $\ge$ 5 cm in maximum diameter) is an important functional component, especially to nutrient cycling in forest ecosystems. To compare mass and nutrient dynamics of CWD in natural oak forests, a two-year study was conducted at Quercus serrata and Q. variabilis stands in Yangpyeong, Kyonggi Province. Total CWD (snag, stump, log and large branch) and annual decomposition mass (Mg/ha) were 1.9 and 0.4 for the Q. serrata stand and 7.5 and 0.5 for the Q. variabilis stand, respectively. Snags covered 72% of total CWD mass for the Q. variabilis stand and 42% for the Q. serrata stand. Most of CWD was classified into decay class 1 for both stands. CWD N and P concentrations for the Q. variabilis stand significantly increased along decay class and sampling time, except for P concentration in 2002. There were no differences in CWD N concentration for the Q. serrata stand along decay class and sampling time. However, CWD P concentration decreased along sampling time. CWD N and P contents (kg/ha) ranged from 3.5∼4.7 and 0.8∼1.3 for the Q. serrata stand to 22.8∼23.6 and 3.7∼4.7 for the Q. variabilis stand. Nitrogen and P inputs (kg/ha/yr) into mineral soil through the CWD decomposition were 0.7 and 0.3 for the Q. serrata stand and 1.6 and 0.3 for the Q. variabilis stand, respectively. The number of CWD and decay rate were main factors influencing the difference in CWD mass and nutrient dynamics between both stands.

Dynamic Susceptibility Contrast (DSC) Perfusion MR in the Prediction of Long-Term Survival of Glioblastomas (GBM): Correlation with MGMT Promoter Methylation and 1p/19q Deletions

  • Kwon, Yong Wonn;Moon, Won-Jin;Park, Mina;Roh, Hong Gee;Koh, Young Cho;Song, Sang Woo;Choi, Jin Woo
    • Investigative Magnetic Resonance Imaging
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    • v.22 no.3
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    • pp.158-167
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    • 2018
  • Purpose: To investigate the surgical, perfusion, and molecular characteristics of glioblastomas which influence long-term survival after treatment, and to explore the association between MR perfusion parameters and the presence of MGMT methylation and 1p/19q deletions. Materials and Methods: This retrospective study was approved by our institutional review board. A total 43 patients were included, all with pathologic diagnosis of glioblastoma with known MGMT methylation and 1p/19q deletion statuses. We divided these patients into long-term (${\geq}60\;months$, n = 7) and short-term (< 60 months, n = 36) survivors, then compared surgical extent, molecular status, and rCBV parameters between the two groups using Fisher's exact test or Mann-Whitney test. The rCBV parameters were analyzed according to the presence of MGMT methylation and 1p/19q deletions. We investigated the relationship between the mean rCBV and overall survival using linear correlation. Multivariable linear regression was performed in order to find the variables related to overall survival. Results: Long-term survivors (100% [7 of 7]) demonstrated a greater percentage of gross total or near total resection than short-term survivors (54.5% [18 of 33]). A higher prevalence of 1p/19q deletions was also noted among the long-term survivors (42.9% [3 of 7]) than the short-term survivors (0.0% [0 of 36]). The rCBV parameters did not differ between the long-term and short-term survivors. The rCBV values were marginally lower in patients with MGMT methylation and 1p/19q deletions. Despite no correlation found between overall survival and rCBV in the whole group, the short-term survivor group showed negative correlation ($R^2=0.181$, P = 0.025). Multivariable linear regression revealed that surgical extent and 1p/19q deletions, but not rCBV values, were associated with prolonged overall survival. Conclusion: While preoperative rCBV and 1p/19q deletion status are related to each other, only surgical extent and the presence of 1p/19q deletion in GBM patients may predict long-term survival.

Relations between Normal Serum Gamma-glutamyltransferase and Risk Factors of Coronary Heart Diseases according to Age and Gender (연령과 성별에 따른 정상 혈청 Gamma-glutamyltransferase와 관상동맥질환 위험인자와의 관계)

  • Kwon, Se Young;Na, Young Ak
    • Korean Journal of Clinical Laboratory Science
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    • v.48 no.1
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    • pp.22-29
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    • 2016
  • Serum gamma-glutamyltransferase (GGT) has been widely used as a marker of alcohol intake and liver failure. Recently, the relativity between GGT and various diseases has been identified with growing interest. In this study, we examined relativity between GGT value and risk factors of coronary heart diseases among those with normal GGT value, excluding heavy drinkers. Specifically, we compared the differences based on age and gender. Data from the 2011 KNHNES were used (N=3,619). When the subjects were categorized according to quartile based on the serum GGT levels, there was 10~20, 21~27, 28~38, 39~71 IU/L in men, and 6~12, 13~16, 17~22, 23~42 IU/L in women. The mean of most variables was the highest in the $4^{th}$ quartile (Q4), however age and LDL Cholesterol were the highest in the $2^{nd}$ quartile (Q2) in men. The FRS and 10-year CHD risk was the highest in the $2^{nd}$ quartile in men, and the highest in the $4^{th}$ quartile in women. Increased GGT was correspondingly linked with age in women but age was the highest in GGT in the $2^{nd}$ quartile in men. In the 70's, the highest Q1 and Q2 was in men and the highest Q3 and Q4 in women. Although GGT value was within the normal range, increased GGT showed correlation with various risk factors. The FRS and 10-year CHD risk showed different patterns according to age and gender along with increased GGT value.

Unbalanced Translocations of Chromosome 2 and Chromosome 20 in a Two-Generation Family (2대에 걸쳐 나타난 염색체 2번과 20번의 비균형적 전위 1례)

  • Min, Saeah;Lim, Seonwoong;Kim, Youngsook;Lee, Ohkyung
    • Clinical and Experimental Pediatrics
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    • v.45 no.7
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    • pp.917-922
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    • 2002
  • An unbalanced translocation is frequently the result of inheritance of an unbalanced haploid set from a parent with a balanced translocation. Families in which one parent is a balanced translocation carrier fall into the following classes : Those in which none of the possible abnormal offsprings is viable; Those in which one type of offspring, usually the one with the smaller deletion, is born alive; Those in which two types of abnormal offspring are viable. We report a neonate whose karyotype was 46,XX,der(2)t(2;7)(q21;p21.2),der(20)t(2;20)(q21;p13). She was small for her gestational age and had multiple anomalies such as exophthalmos, corneal opacity, short neck, tongue tie, clinodactyly, atrial septal defect, patent ductus arteriosus and ventriculomegaly. Moreover, her mother's karyotype was 46,XX,der(2)t(2;7)(q21;p21.2),del(16)(q22.1),der(20)t(2;20)(q21;p13) but her father had normal karyotype. The same derivative chrosomes were found between mother and her infant, except for del(16)(q22.1) in her mother and these same unbalanced translocations in a two-generation family are extremely rare.

Effect of Step Width and TOA on Q-Angle and CTA in Walking (보행에 있어서 보격과 발목각도가 종경골각 및 대퇴사두근각에 미치는 영향)

  • Hwangbo Gak;Lee Jin-Hee;Chung Hyung-Kuk;Bae Sung-Soo
    • The Journal of Korean Physical Therapy
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    • v.8 no.1
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    • pp.33-47
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    • 1996
  • This study was performed to examine the correlation between calcaneus to tibia angle and Q-angle, and the effects of step width and toe out angle on the calcaneus to tibia angle and Q-angle. The age of participated subjects was from 19 to 29 years(Mean=22.95, SD=2.23) who have no significant orthopedic and neurological dysfunction. The marking tapes for measurement of Q-angle and calcaneus to tibia angle were placed on seven location of each subject. Video data were collected while the subject walked on a walking grid. The result as follows : 1. There were significant differences in the step width, toe out angle, and Q-angle but not calcaneus to tibia angle between male and female. 2. There were significant differences in toe calcaneus to tibia angle and Q-angle n step width increased, respectively. 3. There were significant differences between tee out angle and calcaneus to tibia angle but not toe out angle and q-angle. 4. There was statistically significant correlation between calcaneus to tibia angle and Q-angle.

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Litter Production and Nutrient Contents of Litterfall in Oak and Pine Forests at Mt. Worak National Park

  • Mun, Hyeong-Tae;Kim, Song-Ja;Shin, Chang-Hwan
    • Journal of Ecology and Environment
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    • v.30 no.1
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    • pp.63-68
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    • 2007
  • Litter production, nutrient contents of each component of litterfall and amount of nutrients returned to forest floor via litterfall were investigated from May 2005 through April 2006 in Quercus mongolica, Quercus variabilis and Pinus densiflora forests at Mt. Worak National Park. Total amount of litterfall during one year in Q. mongolica, Q. variabilis and P. densiflora forests was 542.7, 459.2 and $306.9\;g\;m^{-2}\;yr^{-1}$, respectively. Of the total litterfall, leaf litter, branch and bark, reproductive organ and the others occupied 50.3%, 22.7%, 10.1 % and 16.9% in Q. mongolica forest, 81.9%, 7.2%, 3.1% and 7.9% in Q. variabilis forest, 57.4%, 12.8%, 5.6% and 24.1 % in P. densiflora forest, respectively. Nutrients concentrations in oak litterfall were higher than those in needle litter. N, P, K, Ca and Mg concentration in leaf litterfall were 13.8, 1.1, 7.2, 4.2 and 1.3 mg/g for Q. mongolica forest, 10.5, 0.7, 3.2, 3.7 and 1.6 mg/g for Q. variabilis forest, 5.3, 0.4, 1.2, 2.8 and 0.6mg/g for P. densiflora forest, respectively. The amount of annual input of N, P, K, Ca and Mg to the forest floor via litterfall was 43.36, 2.89, 21.38, 23.31 and $5.62\;kg\;ha^{-1}\;yr^{-1}$ for Q. mongolica forest, 32.28, 2.01, 10.23, 20.29 and $7.78\;kg\;ha^{-1}\;yr^{-1}$ for Q. variabilis forest, 15.80, 1.04, 3.99, 9.70 and $2.10\;kg\;ha^{-1}\;yr^{-1}$ for P. densiflora forest, respectively.

A Study on Attitude Patterns of Elderly toward Dying (노인의 임종과정에 대한 태도 유형 분석)

  • Kim, Soon-Yi;Kim, Shin-Mi
    • Korean Journal of Adult Nursing
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    • v.15 no.3
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    • pp.343-353
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    • 2003
  • Purpose: This study was performed to identify and understand the nature of attitude patterns regarding dying process exhibited in the elderly persons who lived in the community setting. Method: Q methodology was applied. Ten elderly were selected from the senior centers and requested to answer open ended questions by using written questionnaires. Additionally, 12 other elderly from different senior centers were interviewed in depth, and their statements were recorded via voice pen by researchers to derive Q-population. From the 120 Q-population, 33 Q-sample were selected. 22 P-sample were rated by 1 to 9 point scale respectively for Q-sorting. For Q-type analysis, pc QUNAL was used. Result: Three types of attitude patterns were identified, which were valuing dignity, seeking provision of nature, and avoiding of dying process. Conclusion: The significance of this study is as follows : Discovery of 3 attitude patterns of elderly toward dying, better understanding about elderly's perspectives for favorable dying, and informations for possible development of nursing strategies for elderly who is facing death.

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QTL Analysis of Concerned on Ideal Plant Form in Rice (벼의 이상적인 초형에 관여하는 QTL 분석)

  • Chung, Il Kyung;Kim, Kyung-Min
    • Korean Journal of Plant Resources
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    • v.30 no.2
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    • pp.213-218
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    • 2017
  • Rice is the staple food of at least half of the world's population. Due to global warming, the weather is difficult to forecast nowadays. Therefore, it is necessary to breed various breeding to respond to such changes in the environment. This study was conducted to analyze the QTL about plant form, culm length, ear number and ear length by using 120 lines by anther culture, a cross between the Indica variety Cheongcheong and Japonica variety Nagdong. DNA marker was selected on the QTLs gene, and the following results were obtained. CNDH (Cheongcheong Nagdong Doubled Haploid) lines frequency distribution table curves about culm length, ear number and ear length exhibited showed a continuous variation close to a normal distribution. QTL analysis result, on culm length qPlL1-1 and qPlL1-2 were detected on the chromosome 1 and qPlL5 was detected on the chromosome 5. However, on ear length qPL2, qPL3 and qPL10, were detected on the chromosome 2, 3 and 10, while on ear number qPN1-1 and qPN1-2 were detected on the chromosome 1, qPN9 was detected on the chromosome 9. The QTLs related to culm length was found to chromosomes 5 and LOD scores were 3.81. The QTLs related to ear length was found to chromosomes 2 and 3 LOD scores were 7.13 and 3.20. The QTLs related to ear number was found to chromosome 9 and LOD scores were 4.27. Twenty two (22) Japonica cultivars and 12 Indica cultivars were analyzed polymorphisms, using selected 9 markers from the result about plant form analysis. RM5311, RM555 and RM8111 about the culm length, the ear length and number of ear were selected on the standard of Cheongcheong and Nagdong. Each rate of concordances about the culm length, the ear length and number of ear are 44.11%, 41.17% and 44.11%.