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Cytogenetic Analysis of Three Hemibarbus Species (Cypriniformes) from Korea (한국산 누치속 어류 3종의 세포유전학적 연구)

  • Bang, In-Chul;Lee, Yoon-A;Lee, Wan-Ok
    • Journal of Aquaculture
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    • v.21 no.4
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    • pp.259-264
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    • 2008
  • Cytogenetic characteristics of three Hemibarbus species (H. labeo, H. longirostris and H. mylodon) were analyzed based on erythrocyte measurement, flow cytometric estimation of cellular DNA content, and karyological analysis. Average nuclear volumes for H. labeo, H. longirostris and H. mylodon were 22.5, 21.7 and $26.0\;{\mu}m^3$, respectively. The estimated genome sizes of those three species were not significantly different from one another, being recorded as 2.51, 2.33 and 2.35 pg/cell for H. labeo, H. longirostris and H. mylodon, respectively. Modal chromosome numbers of the three species were the same as 2n = 50. However, their karyotypes and fundamental numbers (FN) were different among species; 16M+16SM+18T/A (FN = 82) for H. labeo, 18M+16SM+16T/A (FN = 84) for H. longirostris and 18M+24SM+8T/A (FN = 92) for H. mylodon.

The Study of the Changes of Obesity-Relating Biomarkers in High Fat Fed-Induced C57BL/6 Mice (고지방 식이로 비만이 유도된 C57BL/6 마우스에서 식이 기간에 따른 비만 관련 지표 변화에 대한 연구)

  • Song, Mi-Young
    • Journal of Korean Medicine for Obesity Research
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    • v.16 no.1
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    • pp.19-26
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    • 2016
  • Objectives: The prevalence of obesity continues rise and obesity and metabolic syndrome is a major problem in global health care. Animal models are used in the drug discovery of novel treatment for obesity. One of common models of obesity is a high fat diet induced obesity in a C5BL/6 mouse, and the development of obesity and glucose tolerance in mouse model is different according to period of diet. Therefore, this study was performed to observe the development of obesity and glucose tolerance during a high fat diet (HFD). Methods: Male C57BL/6 mice, 5 weeks of age, were fed on a standard chow diet as a normal diet (18 kcal% fat) or a HFD (60 kcal% fat) for up to 16 weeks. The various factors related with obesity and insulin resistance were measured at 8, 12, and 16 weeks. Results: The weights of body and epididymal fat were gradually increased for 8~16 weeks, however the change of hyperglycaemia and glucose tolerance have shown different with that of body weight. Blood glucose, oral glucose tolerance and insulin tolerance were increased more clearly at week 12 and 16 than week 8. Lipid accumulation of liver and body temperature were also significantly increased at week 16, compared with normal group. Conclusions: The developments of obesity and related factors were different by a HFD period in a C57BL/6 obese mice. This result suggests that the development of obesity with glucose tolerance and liver lipid may induce clearly by a HFD for 16 weeks.

Methodology of Interoperating Link-K Track Number in Multi TDLs (다중 전술데이터링크 간 Link-K 트랙 번호 상호운용 기술)

  • Lee, Youn-Jeong;Kim, Sang-Jun;Lim, Man-Yeob
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.38C no.12
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    • pp.1186-1195
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    • 2013
  • In modern warfare, the main factor of triumph is superior situation awareness which leads rapid command decision and precisely guided munition, and TDL(Tactical Data Link) is the main communicational enabler. ROK forces currently operate Link-16 with allied forces and are also developing Korean national data link, Link-K which is also planned to be cooperated with Link-16. Assigning participant and track numbers needs agreement between ROK and allied forces, but ROK forces have exclusive authority in assigning numbers in Link-K. This paper proposes the effective method of exchange participant and track numbers between Link-16 and Link-K, and applicability verification in operational test and evaluation will be also presented.

An Approach for Improving Mobile WiMAX Security - ROSMEX Architecture (안전한 모바일 와이맥스 네트워크를 위한 보안 구조 연구)

  • Shon, Tae-Shik;Koo, Bon-Hyun;Choi, Hyo-Hyun
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.47 no.1
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    • pp.25-34
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    • 2010
  • The IEEE 802.16-2004 standard has a security sub-layer in the MAC layer called, Privacy Key Management (PKM). However, several researches have been published to address the security vulnerabilities of IEEE 802.16-2004. After the IEEE 802.16-2004 standard, a new advanced and revised standard was released as the IEEE 802.16e-2005 amendment which is foundation of Mobile WiMAX network supporting handoffs and roaming capabilities. PKMv2 in Mobile WiMAX includes EAP authentication, AES-based authenticated encryption, and CMAC or HMAC message protection. However, Mobile WiMAX still has a problem of security architecture such as a disclosure of security context in network entry, a lack of secure communication in network domain, and a necessity of efficient handover supporting mutual authentication because Mobile WiMAX security has mainly concentrated on between SS and BS communication. Based on the investigation results, we propose a novel mobile WiMAX security architecture, called RObust and Secure MobilE WiMAX (ROSMEX), to prevent the new security vulnerabilities.

p16INK4a is a Useful Marker of Human Papillomavirus Integration Allowing Risk Stratification for Cervical Malignancies

  • Cheah, Phaik-Leng;Looi, Lai-Meng;Teoh, Kean-Hooi;Mun, Kein-Seong;Nazarina, Abdul Rahman
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.2
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    • pp.469-472
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    • 2012
  • The present study was conducted to assess utility of $p16^{INK4a}$ immunopositivity as a surrogate marker for genomic integration of high-risk human papillomavirus infection (hrHPV). A total of 29 formalin-fixed, paraffin-embedded cervical low-grade squamous intraepithelial lesions (LSILs), 27 high-grade squamous intraepithelial lesions (HSILs) and 53 invasive squamous cell carcinomas (SCCs), histologically-diagnosed between 1st January 2006 to 31st December 2008 at the University of Malaya Medical Centre were stained for $p^{16INK4a}$ (CINtec Histology Kit (REF 9511, mtm laboratories AG, Heidelberg, Germany). Immunopositvity was defined as diffuse staining of the squamous cell cytoplasm and or nucleus (involving > 75% of the intraepithelial lesions or SCCs). Staining of basal and parabasal layers of intraepithelial lesions was pre-requisite. One (3.4%) LSIL, 24 (88.9%) HSIL and 46 (86.8%) SCC were $p^{16INK4a}$ immunopositive. All normal squamous epithelium did not express $p16^{INK4a}$. $p16^{INK4a}$ expression was significantly lower (p<0.05) in LSIL compared with HSIL and SCC with no difference in expression between HSIL and SCC. The increased $p16^{INK4a}$ immunopositivity in HSIL and SCC appears in line with the integrated existence of the hrHPV and may provide more insightful information on risk of malignant transformation of cervical squamous intraepithelial lesions than mere hrHPV detection.

Modelling of Differentiated Bandwidth Requests in IEEE 802.16m Systems

  • Yoon, Kang Jin;Kim, Ronny Yongho;Kim, Young Yong
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.7 no.4
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    • pp.726-747
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    • 2013
  • In order to support a large number of mobile stations (MSs) with statistical multiplexing in cellular networks, a random access scheme is widely used for uplink (UL) bandwidth request (BR). In the design of a random access based BR scheme, there are two important requirements: short connection delay and diverse Quality of Services (QoSs) support. Such requirements are crucial for IMT-Advanced systems like IEEE 802.16m to provide various types of fourth generation (4G) data services. IEEE 802.16m provides advanced UL BR schemes for non-real time polling service (nrtPS) and best-effort (BE) service to meet the requirements of short connection time and multiple QoS level support. In order to provide short connection time and multiple QoS support, three-step and differentiated BR procedures are adopted. In this paper, a novel modelling of IEEE 802.16m contention based BR scheme is proposed that uses a 2-dimensional discrete time Markov chain. Both the short access delay three-step BR procedures and normal five-step BR procedure are considered in the model. Our proposed model also incorporates the IEEE 802.16m differentiated BR procedure. With the proposed model, we extensively evaluate the performance of IEEE 802.16m BR for two different service classes by changing QoS parameters, such as backoff window size and BR timer. Computer simulations are performed to corroborate the accuracy of the proposed model for various operation scenarios. With the proposed model, accurate QoS parameter values can be derived for the IEEE 802.16m contention-based BR scheme.