• The Journal of Korean Medicine
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• v.26 no.3 s.63
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• pp.55-65
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• 2005

Objectives : This study was carried out for the development of medicine for vitiligo treatment and focused on the effect of Psoraleae fructus extract on melanin synthesis of B16 melanoma cells. Methods : Activity of tyrosinase playing a vital role in the synthesis and quantity of melanin, which is the final product in cultured B16 melanoma cells, the effects of Psoraleae fructus extract were measured. Results : The results indicated that Psoraleae fructus extract increased beth the amount of melanin and the activity of tyrosinase according to concentration, also supported by western blot analysis. Conclusions : The results suggest that Psoraleae fructus extract has an advantageous effect on the promotion of melanin synthesis and will contribute to the development of vitiligo treatment through further related studies.

• Journal of Nutrition and Health
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• v.25 no.7
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• pp.578-585
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• 1992

This study was undertaken to investigate effects of alcohol and dietary protein levels on serum lipids and enzyme activities in 15 week-old male rats given a normal diet. Rats were divided into 8 groups : control group (16% protein 16PC) and 8%(8PE) 16%(16PE) and 24% protein groups(24PE) to which was given 5% ethanol mixed into their drinking water after 4 weeks and 10 weeks. Body weight organ weight and various blood components were determined at 4 and 10 weeks. Body weight gain organ weight hemoglobin concentration and hematocrit value were not influenced by ethanol and dietary protein levels. The levels of total cholesterol HDL-cholesterol and phospholipid in serum were not affected by ethanol consumption. Serum triglyceride concen-trations after 10 weeks were significnatly increased ethanol-treated group compared with that of control group and the effect was greater in low protein group than control group. Serum ALP activity was significantly higher in 8PE group than other group but there was no influence by ethanol consumption.

• Journal of the Korea Institute of Military Science and Technology
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• v.14 no.2
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• pp.281-288
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• 2011

In this paper, a variable quantization coefficient scanning for macroblock considering the histogram value of previous macroblock's quantization coefficient is proposed. In order to scan a quantization coefficient, the proposed method makes $4{\times}4$ histograms for various prediction modes($16{\times}16$, $16{\times}8$, $8{\times}16$, $8{\times}8$) by adding 1 if the value of quantization coefficient is not 0. After a final mode decision procedure, the $4{\times}4$ histogram of the final mode will be sorted. Then, quantization coefficients in corresponding macroblock of the next frame are scanned using the sorted order. The experimental results show that the proposed scheme reduces the total bits by approximately 0.01~2.25% with similar PSNR performance compared with the previous method.

• Journal of the military operations research society of Korea
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• v.24 no.2
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• pp.43-56
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• 1998

This paper focuses on the optimal replacement time of engine modules of the F16 aircraft. Generally, the optimal replacement time of those should be determined to minimize the replacement cost due to out of order and opportunistic replacement cost of operation cost of remaining period. This paper determined the optimal replacement time by using the opportunistic replacement algorithm that is developed by Forbes and Wyatt. Some real data are utilized but a few data is estimated due to limitation of data. As a result, fan module only reaches to the opportunistic replacement time. The optimal replacement time of the fan module is derived as 1740 cycles. Therefore, the optimal replacement policy of engine modules of the F16 is that fan module should be replaced whenever it is out of order under 1740 cycles and whenever core module is out of order over 1740 cycles.

• Journal of Communications and Networks
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• v.16 no.6
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• pp.620-626
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• 2014

In this paper, we propose a parallel collaborative sphere decoder with a scalable architecture promising quasi-maximum likelyhood performance with a relatively small amount of computational resources. This design offers a hardware-friendly algorithm using a modified node operation through fixing the variable complexity of the critical path caused by the sequential nature of the conventional sphere decoder (SD). It also reduces the computational complexity compared to the fixed-complexity sphere decoder (FSD) algorithm by tree pruning using collaboratively operated node operators. A Monte Carlo simulation shows that our proposed design can be implemented using only half the parallel operators compared to the approach using an ideal fully parallel scheme such as FSD, with only about a 7% increase of the normalized decoding time for MIMO dimensions of $16{\times}16$ with 16-QAM modulation.

• Proceedings of the Korean Association for Survey Research Conference
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• 2000.06a
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• pp.15-34
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• 2000

Since the results of the election forecasting survey that was executed jointly by T.V. stations and survey research companies in the 16th Korea General Election(April 13, 2000) had many errors, the reliability of the election forecasting survey was greatly damaged. Therefore, in order to recover the reliability and to increase the accuracy of the election forecasting survey I the future, we figure out the sources of the survey\\`s errors and suggest methods of reducing them through deeply analyzing the forecasting data from many angles. In addition, we discuss some problems and an improvable direction on exit poll executed for the first time.

• Journal of Microbiology and Biotechnology
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• v.17 no.4
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• pp.668-672
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• 2007

A microcosmal experiment using a metagenomic technique was designed to assess the effect of BTEX (benzene, toluene, ethylbenzene, and xylenes) on an indigenous bacterial community in a Daejeon forest soil. A compositional shift of bacterial groups in an artificial BTEX-contaminated soil was examined by the 16S rDNA PCR-DGGE method. Phylogenetic analysis of 16S rDNAs in the dominant DGGE bands showed that the number of Actinobacteria and Bacillus populations increased. To confirm these observations, we performed PCR to amplify the 23S rDNA and 16S rDNA against the sample metagenome using Actinobacteria-targeting and Bacilli-specific primer sets, respectively. The result further confirmed that a bacterial community containing Actinobacteria and Bacillus was affected by BTEX.

• Journal of Microbiology and Biotechnology
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• v.30 no.5
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• pp.749-752
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• 2020

In the search for novel, natural melanogenesis inhibitors, a new sesquiterpene, inularin, was isolated from the flowers of Inula britannica, and the structure was determined using spectroscopic and chemical methods. The antimelanogenic effects of inularin on B16F10 melanoma cells and zebrafish embryos were evaluated. Inularin dose-dependently reduced melanocyte-stimulating hormone-induced melanin production and L-DOPA oxidation in B16F10 cells. Zebrafish embryos were used to confirm the antimelanogenic activity. Inularin significantly decreased the pigmentation of embryos compared with untreated controls.

• Journal of the Korean Society of Systems Engineering
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• v.2 no.1
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• pp.18-23
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• 2006

The purpose of this study and report is to provide, to the MND, an independent cost analysis of modernizing software of F-16 fighter fleets to support the use of several weapon system options, including JDAM, AIM-9X and HARM Targeting System etc. The study analyzed each options with software sizing, software cost, enabling hardware cost, flight test cost, system engineering cost, and 3 strategies. And the study proposed and analyzed some alternative strategies: strategy1 is to modernize software only within existing electronic processing capability; strategy2 is a full upgrade of weapons avionics with plug compatible electronics; strategy3 is an approach defined to mirror the USAF Common Configuration Implementation Approach (CCIP). The recommended alternative is strategy2.

• Journal of Korean Society for Quality Management
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• v.38 no.3
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• pp.333-339
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• 2010

It is difficult to determine an optimal inventory level of aircraft engine and modules to achieve the target operational availability since F100-PW-200 & 229 engines of the F-16 & KF-16 aircraft are consisted of 5 modules with different failure rates and costs. This study presents a decision model, combining an integer programming problem and a regression metamodel. Data for the metamodel was attained from results of a simulation model, that represents operational and repair process of F-16 and KF-16. The objective function of an integer programming problem is maximizing the operational availability, representing pessimistic circumstances. Finally, an integer programming problem with a metamodel can make an optimal decision of the inventory level.