• Asian Pacific Journal of Cancer Prevention
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• v.16 no.16
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• pp.6841-6843
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• 2015

Omega-3 polyunsaturated fatty acids (${\omega}$-3 PUFAs) are essential nutrients for human beings and their potential roles against cancer development and progression have become of wide concern recently. Some studies have suggested that perioperative supplementation with omega-3 fatty acids may have beneficial effects in gastrointestinal cancer patients undergoing surgery, while other researchers reported contrary results. This paper reviews recent research to establish therapeutic effects as well as possible underlying mechanisms of ${\omega}$-3 PUFA actions, and to help explain possible reasons for inconsistent results from different institutions.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.16
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• pp.6831-6839
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• 2015

Multidrug resistance is a principal mechanism by which tumors become resistant to structurally and functionally unrelated anticancer drugs. Resistance to chemotherapy has been correlated with overexpression of p-glycoprotein (p-gp), a member of the ATP-binding cassette (ABC) superfamily of membrane transporters. P-gp mediates resistance to a broad-spectrum of anticancer drugs including doxorubicin, taxol, and vinca alkaloids by actively expelling the drugs from cells. Use of specific inhibitors/blocker of p-gp in combination with clinically important anticancer drugs has emerged as a new paradigm for overcoming multidrug resistance. The aim of this paper is to review p-gp regulation by dietary nutraceuticals and to correlate this dietary nutraceutical induced-modulation of p-gp with activity of anticancer drugs.

• 한국생물공학회:학술대회논문집
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• 2001.11a
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• pp.910-913
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• 2001

The fatty acid compositions of entomopathogenic nematodes Steinernema carpocapsae strain produced in vitro and in vivo were examined. Nematodes cultured both in vitro and in vivo revealed similar fatty acids compositions with respect to 16, 18, 20 carbons. However, the contents of lipids were varied by culture methods. Furthermore, it was distinctive that nematodes cultured in vitro contained fatty acids with 19 carbon. In the case of symbiotic bacterium Xenorhabdus nematophilus isolated from Steinernema carpocapsae, the major lipid component was palmitic (c16:0) fatty acids.

• The Research Journal of the Costume Culture
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• v.7 no.2
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• pp.242-256
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• 1999

A Study on the construction of Chulik in the early 16th century based on the shrouds from the excavated grave of Kim, Heum-Jo(1461∼1528) is reported in this paper. This paper first reviews the general construction methodology found in the shrouds from other graves in early 16th century revealed from a report on Chulik from the excavated grave of Kim, Heumjo. This paper finds that there exist at least three different Chulik forms according to the ratios between upper portion and lower portion in Chulik. The upper portion to the lower portion ratio grows with time. Among the three forms, this Chulik of interest falls in the first one of the three forms. This new finding of the chronological evidence for the first category of the three forms provides us the latest chronology for the first category, which is up to the year 1567. This paper also shows that the second and the third categories of Chulik in early Chosun Dynasty lasted until 1580\`s and until 1590\`s, respectively. Several remarks on construction methodology found in the Chulik of interest are also reported in this paper.

• Proceedings of the Korean Institute of Intelligent Systems Conference
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• 2000.11a
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• pp.319-322
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• 2000

본 논문에서는 지문영상으로부터 제안한 알고리즘을 이용하여 특이점(Core, Delta)을 추출한 후 특이점의 개수와 종류에 따라서 5가지 부류(arch, tented arch, left loop, right loop, whorl)로 지문영상을 분류하였다. 지문영상을 8*8블록과 16*16블록으로 분할한 후 3*3 Sobel 마스크를 씌워서 대표 방향을 구하였다. 또한 블록으로 분할한 영상으로부터 분산을 구하여 전경과 배경을 분리(segmentation)시켜 수행속도를 향상시켰다. 전처리 과정으로는 일정한 블록마다 임계값을 다르게 적용시키는 블록 이진화 기법을 사용하였으며 특이점을 추출하기 위해서 서로 크기가 다른 2개의 블록으로 영상을 분할하였다. 우선 8*8블록으로 영역을 분할한 후 방향 성분을 구하고 특이점들을 추출하였다. 이 경우 잡영 때문에 특이점이 너무 많이 추출되는 문제점이 있으므로 이러한 해결책으로 16*16블록으로 영역을 분할하여 방향 성분을 구하고 특이점을 추출하였다. 이렇게 다른 두 영역에서 동시에 나타나는 특이점을 후보 특이점으로 잡아서 그 후보 특이점 주변으로 Poincare 지수를 적용하여 확실한 특이점을 선택한 후 5가지의 지문 형태로 분류하였다. 실험결과 대부분의 지문영상에 대하여 강건한 분류 특성을 보이고 있음을 확인하였다.

• Molecules and Cells
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• v.27 no.1
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• pp.55-66
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• 2009

The phylogeny of the family Tephritidae (Diptera: Tephritidae) was reconstructed from mitochondrial 12S, 16S, and COII gene fragments using 87 species, including 79 tephritid and 8 outgroup species. Minimum evolution and Bayesian trees suggested the following phylogenetic relationships: (1) A sister group relationship between Ortalotrypeta and Tachinisca, and their basal phylogenetic position within Tephritidae; (2) a sister group relationship between the tribe Acanthonevrini and Phytalmiini; (3) monophyly of Plioreocepta, Taomyia and an undescribed new genus, and their sister group relationship with the subfamily Tephritinae; (4) a possible sister group relationship of Cephalophysa and Adramini; and (5) reconfirmation of monophyly for Trypetini, Carpomyini, Tephritinae, and Dacinae. The combination of 12S, 16S, and COII data enabled resolution of phylogenetic relationships among the higher taxa of Tephritidae.

• Journal of Microbiology and Biotechnology
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• v.6 no.6
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• pp.375-380
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• 1996

The gene coding for glutaryl-7-aminocephalosporanic acid (GL-7-ACA) acylase was cloned from Pseudomonas sp. GK16 and some of its characteristics were analyzed. The complete nucleotide sequence revealed that the putative open reading frame is 2160 bases long and encodes 720 amino acids. By SDS-PAGE three proteins, approximately corresponding to 70, 54 and 16 kDa of molecular weight, were detected in E. coli cells carrying pGAP18. The largest protein should be a precursor which is not processed yet, while the other two proteins must be derived from the precursor by the proteolytic processing.

• Journal of Pharmacopuncture
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• v.9 no.1
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• pp.75-82
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• 2006

Objective : This research was carried out for the development of medicine for vitiligo treatment and focused on the effect of Hominis Placenta extract on Melanin synthesis of B16 melanoma cells. Methods : Acitivity of tyrosinase playing a vital role in synthesis of Melanin and the quantity of Melanin, which is the final product in cultured B16 melanoma cells, effects of Hominis Placenta extract were measured. Results: The results indicated that Hominis Placenta extract increased both the amount of Melanin and the activity of tyrosinase according to the concentration, and they also supported by western blot analysis. Conclusion : The results suggests that Hominis Placenta extract has an advantageous effect on the promotion of Melanin synthesis and will contribute to the development of vitiligo treatment through further related studies.

• Ocean Science Journal
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• v.41 no.4
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• pp.315-318
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• 2006

Three Synechococcus strains were isolated from seawater near the Ieodo Ocean Research Station (IORS), and their 16S rDNA genes and the internal transcribed spacer (ITS) between the 16S and 23S rRNA genes were sequenced to investigate their phylogenetic relationships. Phylogenetic trees based on the 16S rDNA and ITS sequences showed that they clustered in the main MC-A Synechococcus group (subcluster 5.1), but formed branches differentiating them from the described clades. As the IORS is located in an area affected by diverse water masses, high Synechococcus diversity is expected in the area. Therefore, the IORS might be a good site to study the diversity, physiology, and distribution of the Synechococcus group.

• Biomolecules & Therapeutics
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• v.11 no.2
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• pp.151-156
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• 2003

Cornis fructus have various biological effects and major chemical components have been tannins, saponins, ursolic acids, gallic acids, linoleic acids, morronisides, cornins and loganins. The main aim of the present study is measurment the effect of chloroform extract from Cornis fructus on proliferation inhibition and Cell death. Cells were cultured in the presence of chloroform extracts from Cornis fructus for 48 h. after 48h treatment of B16/F10 melanoma cells with chloroform extracts, the cells were observed a dose-dependent inhibitions of cell viability with cell death in their proliferation. the cells were estimated cell viability, cell number, total DNA fragmentation and chromatin condensation in a dose-dependent manner. It also caused cell death as measured by cell morphology, DNA fragmentation and nucleus chromatin condensation. therefore, these results suggest that chloroform extracts from C. fructus is inhibitory proliferation and is related to cell death in this cells.