• YAKHAK HOEJI
• /
• v.33 no.2
• /
• pp.118-123
• /
• 1989

A new polyacetylene compound which has strong cytotoxic activity against L1210 cell, was isolated from Korean ginseng roots. The structure was determined to be heptadeca-1-ene-4,6-diyne-3,9-diol-10-acetate (10-acetyl panaxytriol, $ED_{50}\;=\;1.2\;{\mu}g/ml$). The cytotoxicities of this compound and acetyl panaxydol lower than their starting substances, panaxytriol and panaxydol. The presence of one for the decreases in the cytotoxicities.