• Steel and Composite Structures
• /
• 제22권1호
• /
• pp.63-77
• /
• 2016

Top-down construction is a construction technique in which pit excavation and structure construction are conducted simultaneously. Reducing construction time and minimizing noise and vibration which affect neighboring structures, the technique is widely employed in constructing downtown structures. While H-steel columns have been commonly used as core columns, concrete filled steel tube (CFT) columns are at the center of attention because the latter have less axial directionality and greater cross-sectional efficiency than the former. When compared with circular CFT columns, square CFT columns are more easily connected to the floor structure and the area of percussion rotary drilling (PRD) is smaller. For this reason, square CFT columns are used as core columns of concrete encased and filled square (CET) columns in underground floors. However, studies on the structural behavior and concrete stress transfer of CET columns have not been conducted. Since concrete is cast according to construction sequence, checking the stress of concrete inside the core columns and the stress of covering concrete is essential. This paper presents the results of structural tests and analyses conducted to evaluate the usability and safety of CET columns in top-down construction where CFT columns are used as core columns. Parameters in the tests are loading condition, concrete strength and covering depth. The compressive load capacity and failure behavior of specimens are evaluated. In addition, 2 cases of field application of CET columns in underground floors are analyzed.

• 한국생물정보학회:학술대회논문집
• /
• 한국생물정보시스템생물학회 2005년도 BIOINFO 2005
• /
• pp.173-182
• /
• 2005

A three dimensional (3D) model for the catalytic region of Type II Pseudomonas sp. USM 4-55 PHA synthase 1 (PhaC1$_{P.sp\;USM\;4-55}$) from residue 267 to residue 484 was developed. Sequence analysis demonstrated that PhaC1$_{P.sp\;USM\;4-55}$ lacked homology with all known structural databases. PSI-BLAST and HMM Superfamily analyses demonstrated that this enzyme belongs to the ${\alpha}/{\beta}$ hydrolase fold family. Threading approach revealed that the most suitable template to use was the Human gastric lipase (1HLG). The superimposition of the predicted PhaC1$_{P.sp\;USM\;4-55}$ model with the 1HLG template structure covering 86.2% of the backbone atoms showed an RMSD of 1.15 ${\AA}$ The catalytic residues comprising of Cys296, Asp451, His452 and His479 were found to be conserved and were located adjacent to each other. We proposed that the catalytic mechanism involved the formation of two tetrahedral intermediates.

• 천문학회보
• /
• 제39권2호
• /
• pp.93.1-93.1
• /
• 2014

The reflection nebula NGC 7023 is a typical example of a photodissociation region (PDR), which consists of high density molecular gas that is exposed to an intense UV radiation field. The source of the UV photons in NGC 7023 is the young pre-main-sequence Be star HD 200755. We present our near-infrared high-resolution (R ~ 40,000) spectrum of NGC 7023, covering a region of $1{\times}15$ arcseconds, observed during the commissioning runs of IGRINS (Immersion GRating near-INfrared Spectrometer). The spectrum shows many strong narrow emission lines that arise from the molecular rovibrational transitions of H2. From the intensity ratios between these H2 lines, we investigate physical conditions within the PDR such as the temperature, density, and pressure. The high spectral resolution of IGRINS allows us to resolve the velocity field of the PDR. In addition, we compare the IGRINS spectrum to Cloudy PDR model.

• 대한자기공명의과학회:학술대회논문집
• /
• 대한자기공명의과학회 2001년도 제6차 학술대회 초록집
• /
• pp.111-111
• /
• 2001

목적： To evaluate the feasibility of the event-related functional MR study using power grip studying the hand motor system 대상 및 방법： Event-related functional MRI was performed on a 1.5T MR unit in seven norm volunteers (man=7, right-handedness=2, left-handedness=5, mean age： 25 years). A single-shot GRE-EPI sequence (TR/TE/flip angle： 1000ms/40ms/90, FOV = 240 mm matrix= 64$\times$64, slice thickness/gap = 5mm/0mm, 7 true axial slices) was used for functiona MR images. A flow-sensitive conventional gradient echo sequence (TR/TE/flip angl 50ms/4ms/60) was used for high-resolution anatomical images. To minimize the gross hea motion, neck-holders (MJ-200, USA) were used. A series of MR images were obtained in axial planes covering motor areas. To exclude motion-corrupted images, all MR images wer surveyed in a movie procedure and evaluated using the estimation of center of mass of ima signal intensities. Power grip task consisted of the powerful grip of all right fingers and hand movement ta used very fast right finger tapping at a speed of 3 per 1 second. All tasks were visual-guid by LCD projector (SHARP, Japan). Two tasks consisted of 134 phases including 7 activatio and 8 rest periods. Active stimulations were performed during 2 seconds and rest period were 15 seconds and total scan time per one task was 2 min 14 sec. Statistical maps we obtained using cross-correlation method. Reference vector was time-shifted by 4 seconds an Gaussian convolution with a FWHM of 4 seconds was applied to it. The threshold in p val for the activation sites was set to be 0.001. All mapping procedures were peformed usin homemade program an IDL (Research Systems Inc., USA) platform. We evaluated the activation patterns of the motor system of power grip compared to hand movement in t event-related functional MRI.

• Bulletin of the Korean Chemical Society
• /
• 제33권2호
• /
• pp.647-650
• /
• 2012

Promising anticancer compounds of the type 1,6-disubstituted 4,5,6,7-tetrahydropyrazolo[3,4-c]pyridin-7-ones were identified. The target compounds were readily synthesized in a large scale via a sequence of reactions starting from the commercially available primary amines. Their in vitro anti-proliferative activity has been evaluated on prostate (DU-145), colon (HT-29 and HCT-116) and melanoma (A375P) human cancer cell lines. The relationships between the structure and the anticancer activity, covering all tested cancer cell lines, revealed that the compound 5c with 2,4-dimethylphenyl substituent at $R^2$ was the most potent with the $IC_{50}$ values in the range as low as 0.16 to $0.40{\mu}M$.

• Investigative Magnetic Resonance Imaging
• /
• 제12권1호
• /
• pp.27-32
• /
• 2008

목적: 점구분-분광술을 이용한 여기법과 나선형 판독경사를 이용하여 삼차원 화학적변위영상을 개발하고자 하였다. 대상 및 방법: 상수 밀도를 갖는 나선형 판독경사를 디자인하는 분석식을 이용하여 스캐너에서 실시간으로 각종 지표들을 바꿀수 있도록 개발하였다 ($32{\times}32$ 행렬, $24{\times}24\;cm$ FOV). 생체내 뇌 데이터를 수집하였고 그리딩 알고리즘을 이용하여 분광학 영상을 재구성하였다. 결과: 본 연구에서 개발한 영상 기법을 이용하면, 점구분 분광술의 이점인 뇌 표면의 지방의 신호를 제거하면서 나선형 패턴이 갖는 장점들을 이용할 수 있다. 나선형 샘플링은 영상을 얻는데 걸리는 시간과 영상의 해상도를 자유로이 조절할 수 있는 유연성을 가지고 있다. 삼차원 고해상도 점구분-분광술 영상을 $5760\;cm^3$의 공간에서 얻는데 걸리는 총 시간이 12.5 분이었다. 결론: 점구분 분광술과 나선형 샘플링을 결합하여 삼차원 화학적 변위 영상을 얻는 새로운 방법을 개발하였다. 이를 통해 넓은 공간을 확보하며 동시에 지방 신호를 제거하는 기법을 사용할수 있게 되었다.

• Journal of Species Research
• /
• 제13권3호
• /
• pp.318-325
• /
• 2024

Bacterial communities residing on islands have a significant impact on the functioning and establishment of a unique isolated ecosystem. Notwithstanding, systematic research on the indigenous microbial resources of domestic islands has been lacking. In order to understand the biodiversity and potential bioresources, we conducted sampling in 2023 from coastal waters from various islands off the west coast of the Korean Peninsula, including Baengnyeongdo, Daebudo, Deokjeokdo, Jangbongdo, Yeonpyeongdo Islands, along with Somaemuldo Island along the south coast. The coastal seawater samples were used to unearth microbial resources through the standard dilution plating. In total, approximately 1,600 bacterial strains were isolated from the samples as single colonies and identified using 16S rRNA gene sequence analyses. Eighteen strains, exhibiting ≥98.7% 16S rRNA gene sequence similarity to bacterial species with validly published names but not previously reported in Korea, were categorized as unrecorded bacterial species in Korea. These unrecorded bacterial strains displayed phylogenetic diversity, representing three phyla, four classes, 9 orders, 13 families, and 18 genera. The unrecorded species were assigned to the classes Alphaproteobacteria (Aliiroseovarius, Kiloniella, Maritalea, Palleronia, and Roseobacter), Gammaproteobacteria (Aliamphritea, Aliivibrio, Enterovibrio, Francisella, Leucothrix, Pseudoalteromonas, Psychrobium, Shewanella, and Vibrio), Flavobacteriia (Aquimarina, Pseudofulvibacter, and Tenacibaculum), and Verrucomicrobiae (Roseibacillus). This study presents comprehensive descriptions of the taxonomic attributes of these unrecorded species, covering morphology, biochemistry, and phylogenetic position.

• ETRI Journal
• /
• 제18권4호
• /
• pp.265-286
• /
• 1997

This paper presents a new software development environment that supports an integrated methodology for covering all phases of software development and gives integrated methods with tools for ITUT (Telecommunication Standardization Section of the International Telecommunication Union) languages. The design of the environment to improve software productivity and quality is based on five main concepts: 1) formal specifications based on SDL (Specification and Description Language) and MSC (Message Sequence Charts) in the design phase, 2) verification and validation of those designs by tools, 3) automatic code generation and a safe separate compilation scheme based on CHILL (CCITT High-Level Language) to facilitate programming-in-the-many and programming-in-the-large. 4) debugging of distributed real-time concurrent CHILL programs, and 5) simulation of application software for integrated testing on the host machine based on CHILL. The application results of the environment compared with other approaches show that the productivity is increased by 19 % because of decreasing implementation and testing cost, and the quality is increased by 83 % because of the formal specifications with its static and dynamic checking facilities.

• 한국식물병리학회:학술대회논문집
• /
• 한국식물병리학회 2003년도 정기총회 및 추계학술발표회
• /
• pp.146.2-147
• /
• 2003

Two Korean isolates of Alfalfa mosaic virus (AHV-AZ, AMV-KR) were isolated from azuki bean and potato plants, respectively, and their pathologies were confirmed on some susceptible host plants including pepper, tobacco and red bean plants. Full length cDNAs to RNA1, RNA2 and RNA3 of the two Korean strains were amplified using the long-template reverse transcription (RT)-polymerase chain reaction (PCR) method. RT-PCR products covering entire regions for the three AMV genome RNAs were cloned. RNA transcripts were synthesized in vitro from each clones using T7 RNA polymerase and infectivity test was peformed in 9 reassortment sets of transcripts. All the combinations of reassorted transcripts were found to be infectious when inoculated onto Nicotiana benthamiana plants, and were not distinguishable to those of wild types. The full-length cDNA clones that were confirmed infectious were sequenced their nucleotide sequences. We will discuss sequence analysis of the two Korean isolates of AMV genomic RNA3 and compare reported foreign isolates of AMV.

• 대한수의학회지
• /
• 제44권2호
• /
• pp.311-315
• /
• 2004

The detection of lymph node metastasis is an important step in tumor staging and is significant for therapy planning. It has been challenged to yield an appropriate image with diagnostic methods such as Magnetic Resonance (MR) and Computed Tomography (CT). Though CT has been used widely and accessed easily to show internal organs, it can hardly provide difference between lymph node and adjacent vessel or fat tissue. It has been well established that MR can reveal the subtle discrepancy within soft tissue. This study investigated the suitability of MR lymph node imaging without contrast enhancement by comparison of T1-weighted image (T1WI) and T2- weighted image (T2WI) in ten normal rabbits. According to the pulse sequence optimized from preliminary study, T1-weighted spin-echo (repetition time/echo time=400/12 ms) and T-2 weighted fast spin-echo (repetition time/echo time=3500/84 ms) images covering the hind limbs and pelvic region were acquired at 1.5 T. Two radiologists scrupulously evaluated the MR images in consensus. And signal intensity of lymph nodes was compared with that of adjacent fat. Statistical analysis showed that T1-weighted coronal image visualized the lymph nodes (iliac, superficial inguinal and popliteal lymph nodes) quickly and consistently rather than T2-weighted one. Conclusively, T1WI for evaluation of lymph nodes is moderately better than T2WI and appears to have potential for quick and sufficient mapping of the lymph nodes. In addition, this normal MR image of lymph nodes could be applied to further study for the evaluation of lymphatic system in abscess and tumor bearing animal model.