• 월간산업보건
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• 통권88호
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• pp.57-60
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• 1995

PAT program(The Proficiency Analytical Testing Program)은 미국산업위생협회(American Industrial Hygiene Association AIHA)와 미국산업안전보건연구원(National Institute for Occupational Safety and Health NIOSH)에서 공동주관하는 정도관리로서 일년에 4회 실시하고 있다. 실시항목은 금속(납, 카드뮴, 크롬, 아연), 유리규산, 석면, 유기,용제(Benzen, O-Xylene, Toluene, Carbon Tetrachloride, 1, 1, 1-Trichloroethane, Chloroform, Tetrachloroethylene, 1, 2-Dichloroethane, methanol, p-Dioxane)이다. 대한산업보건협회 산업보건연구소에서는 위의 4가지 항목을 모두 신청하여 1995년 1월에 실시된 120회 부터 참여하였는데 다음은 본 연구소의 120화에 대한 분석방법과 NIOSH로 부터 받은 결과이다.

• 멤브레인
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• 제9권1호
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• pp.10-16
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• 1999

본 연구에서는 pellet 상태의 polyetherimide (PEI)를 carbon tetrachloride(CCl4)와 1 ,2-dichloro-ethane (DCE) 의 부피비 5:1 하에서 PEI를 불균일한 상태로 유지시키고, chlorosulfonic acid (CSA)를 이용하여 PEI의 표면을 sulfonation 시킴으로써 , 음이온성을 띠며 친수성이 향상된 sulfonated polyetherimide (SPEI)를 제조하였다. 불균일한 상태가 유지되면서 가장 적합한 sulfonation 반응조건은 PEI: CSA 의 1 : 1 mole ratio, 온도 $10^{\circ}$, 3 시간이었다. 이온교환용량이 0.2~1.2meq/g을 갖는 SPEI를 합성할 수 있었고, FT-IR 측정을 통하여 sulfonic acid peak가 1020$cm^{-1}$ 와 1170$cm^{-1}$부근에서 관찰되었다. 분자량 분포는 sulfonation을 시킴으로써 좀 더 넓게 나타났고, 접촉각 측정을 통하여 친수성이 향상되었음을 확인하였다.

• 약학회지
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• 제27권4호
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• pp.303-307
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• 1983

Pipethanate*HCl reacts with ammonium cobaltothiocyanate to form a stable ion pair which has an absorption maximum at 626nm. The reaction product was insoluble in water but freely soluble in most organic solvents. 1, 2-Dichloroethane was the best extracting solvent among the several organic solvents. Pipethanate*HCl can be determined not only by the spectrophotometry but also inderectly by estimation of cobalt in the organic phase by atomic absorption spectrophotometry. Linear relationship was found between absorbance and concentration in the range of $1.0{\times}10^{-3}~4.0{\times}10^{-3}M$ by spectrophotometry and $1.5{\times}10^{-4}~4.0{\times}10^{-4}M$ by atomic absorption spectrophotometry. With this method it was possible to determine pipethanate$\cdot$HCl in the pharmaceutical preparations.

• 생약학회지
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• 제35권1호통권136호
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• pp.88-91
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• 2004

Abstract - The Evodiae Fructus is known for containing a number of indolquinazoline and quinoline type alkaloids. Evodiamine, evocarpine and rutaecarpine are the major constituents of alkaloids. These alkaloids were isolated and determined by forming complex compounds from Evodiae Fructus in O-Su-You-Tang. For the determination of these alkaloids, a new spectrophotometric method was developed with a simple and selective sample clean-up using thiocyanatocobaltate[II] compIεx compound ion. The absorbance of alkaloidal complex compounds in 1,2-dichloroethane solution was measured at 625 nm. The method proved to be rapid, simple and reliable for the isolation and the determination of the alkaloids in O-Su-You-Tang.

• Journal of Microbiology
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• 제41권4호
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• pp.277-283
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• 2003

Haloaliphatic hydrocarbons have been widely used as solvents and ingredients of pesticides and herbicides. However, when these compounds contaminate the environment, they can be very hazardous to animals and humans because of their potential toxicity and carcinogenicity. Therefore, lots of studies have been made for microbial degradation of those pollutant chemicals. In this study, 11 bacterial strains capable of degrading 1,2-dichloroethane (1,2-DCA), 2-chloropropionic acid (2-CPA), 2,3-dichloropropionic acid (2,3-DCPA), and 2-monochloroacetic acid (2-MCA) by hydrolytic dechlorination under aerobic conditions were isolated from wastewaters and rice paddy soil samples. Their morphological and biochemical characteristics and their degradation capabilities of haloaliphatic hydrocarbons were examined. On the basis of the 16S rDNA sequences, 8 different kinds of microbial species, including Pseudomonas plecoglossicida, Xanthobacter flavus, Ralstonia eutropha, were identified. All of the isolated strains can degrade MCA. In particular, strains UE-2 and UE-15 degraded 1,2-DCA, and strain CA-11 degraded 2,3-DCPA, which are hardly degraded by other strains.

• 한국광학회:학술대회논문집
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• 한국광학회 1989년도 제4회 파동 및 레이저 학술발표회 4th Conference on Waves and lasers 논문집 - 한국광학회
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• pp.13-19
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• 1989

Passive mode-locking of a pulsed Nd:YAG laser is achieved with saturable absorbers, BDN dye in iodoethane solvent and Kodak Eastman # 26 dye in 1,2-dichloroethane solvent, and its optimum conditions are investigated. The thickness of saturable absorbers employed in the laser mode-locking is 0.16~0.50mm. The PBR (peak-to-background ratio) measured in the oscilloscope is 79.8% in Kodak Eastman # 26 dye at the neighbourhood of the peak power, whereas the passive mode-locking with BDN dye gives PBR of 67.7%. BDN and Kodak Eastman # 26 dyes are superior in photostability over Kodak eastman # 9860 and # 9740 dyes which were used previously in passive mode-locking. From the PBR curve, we find that Kodak Eastman # 26dye is more effective than BDN dye in passive mode-locking. The spacing between the adjacent pulses of the pulse train, which depends on the laser cavity length, is measured and is found to be 7 nsec for the cavity length of 100cm.

• 전기화학회지
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• 제10권3호
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• pp.159-168
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• 2007

An electrochemical study related to the redox characteristics of Ethyl-3-acetyl-6-methyl-1, 4-diphenyl-4, 3a-dihydro-1, 3, 4-triazolino[3, 4-a] pyrimidine-5-carboxylate ester and its derivatives (1a-f) and (2a-e) in nonaqueous solvents such as 1, 2-dichloroethane (DCE), dichloromethane (DCM), acetonitrile (AN), dimethylsulphoxide (DMSO) and tetrahydrofurane (THF) using $0.1\;mol\;dm^{-3}$ tetrabutylammonium perchlorate (TBAP) as a supporting electrolyte at platinum, glassy carbon and gold electrodes, has been performed using cyclic voltammetry (CV). Controlled potential electrolysis (CPE) is also carried out to elucidate the course of different electrochemical reactions through the separation and identification of the intermediates and final electrolysis products. The redox mechanism is suggested and proved. It was found that all the investigated compounds in all solvents are oxidized in a single irreversible one electron donating process following the well known pattern of the EC-mechanism to give a dimer. On the other hand, these compounds are reduced in a single irreversible one electron step to form the anion radical, which is basic enough to proton from the media forming the radical which undergoes tautomerization and then dimerization processes to give also another bis-compound through N-N linkage formation.

• 약학회지
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• 제44권2호
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• pp.135-140
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• 2000

Determination of Aconitum alkaloids in processed Buza (Cho-0, Salted Buza, Moist-heating Buza, Limed Buza), which had been prepared from the raw tubers of Aconitum chiisanenseb(Ranunculaceae), was established using visible spectrophotometry and high-performance liquid chromatography (HPLC) method especially for Aconitine analysis. Aconitum alkloids were reacted with tetra- thiocy-anatocobalt[II] complex ion to form a stable ion pair. The reaction product was insoluble in water but freely soluble in several organic solvents. 1.2-Dichloroethane was the best extracting solvent among the examined solvents. Spectrophotometry of Aconitum alkaloids at nax. 625 was carried out. The HPLC method for aconitine was carried out using Radial PAK-CN column with gradient solvent system by solvent mixture of acetonitrile and phosphate buffer (pH 3.0) at 4$0^{\circ}C$ and 254 nm. Linear relationship was found between absorbance response and concentration of aconitine in range of 0.45 mM~0.9 mM ($r^2$=0.9949) by spectrophotometry and 0.3 mM~1.2mM($r^2$=0.9983) by HPLC method. These methods have been found to be suitable and reproducible for routine analysis of Aconitum alkaloids and its pharmaceutical preparations.

• Archives of Pharmacal Research
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• 제22권6호
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• pp.585-591
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• 1999

The linker which plays a role in connecting a polymer with a scaffold has become an important part n solid-phase reaction. To develop a new linker for alcohols and carbohydrates, dihydropyran moiety was selected in this study. New linker, 1-($4^{l},5^{l}$-dihydro-5H-pyranyl)-7-hydroxyheptan-3-one (5) was synthesized via four steps from $\delta$-valerolactone. This can be called as DDHP-linked Wang resin due to double dihy-dropyran rings. To the one pyran ring of new linker 5 was added Wang resin and other alcohols and carbohydrates as scaffolds were then added successfully to the another pyran ring. Carbohydrate and hydroxyl resins were connected via new linker in a 70% loading yield. The detachment of glucose moiety in the presence of PPTS (2 equiv.) in 1:1 n-buteanol/1,2-dichloroethane at $60^{\circ}C$ for 12 h was carried out quantitatively. When certain combinatorial chemical works are carried out using this dihydropyran linker, Wang resin itself can be recovered. Its fact is particularly very important in industry, because recovered resins can be recycled.

• The Korean Journal of Physiology and Pharmacology
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• 제4권2호
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• pp.159-167
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• 2000

We have synthesized a novel platinum(II) coordination complex containing cis-1,2-diaminocyclohexane (DACH) as a carrier ligand and 1,2-dichloroethane (DCE) as a leaving group. In addition, nitrate was added to improve the water-solubility. A new series of [Pt(cis-DACH)(DCE)] $2NO_3(PC)$ was evaluated for its cytotoxic activity on T-24 and J-82 human bladder carcinoma cells and normal primary cultured kidney cells. PC has demonstrated high levels of cytotoxicity against T-24 and J-82 cells. The cytotoxicity of PC against rabbit proximal renal tubular cells, human renal cortical cells and human renal cortical tissues, determined using the MTT assaying technique, the $[^3H]-thymidine$ uptake and glucose consumption tests, was found to be quite less than those of cisplatin. Based on these results, this novel platinum(II) coordination complex appears to be better for improving antitumor activities with low nephrotoxicity and is a valuable lead in the development of new clinically available anticancer chemotherapeutic agents.