• Title/Summary/Keyword: 1,1-dimethylprop-2-enyl $1-O-{\beta}-D-gluco-pyranoside$

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Development of Biologically Active Compounds from Edible Plant Sources-VIII. - Isolation of Platelet Aggregation Inhibitory Compounds from the Arils of Euphoria longana L. - (식용 식물자원으로부터 활성물질의 탐색-VIII. - 용안육(Euphoria longana L.)으로부터 분리된 uridine의 혈소판 응집 저해 효과 -)

  • Kim, Dong-Hyun;Song, Myoung-Chong;Choi, Jung-Min;Kim, Sung-Hoon;Kim, Dae-Keun;Chung, In-Sik;Park, Mi-Hyun;Kwon, Byoung-Mog;Baek, Nam-In
    • Applied Biological Chemistry
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    • v.47 no.1
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    • pp.130-134
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    • 2004
  • The arils of Euphoria longana L. was extracted with 80% aqueous MeOH, and the concentrated extract was partitioned with EtOAc, n-BuOH and $H_2O$. From the n-BuOH fraction, four compounds were isolated through the repeated silica gel, ODS and Sephadex LH-20 column chromatographies. From the result of physico-chemical data including NMR, MS and IR, the chemical structures of the compounds were determined as 1,1-dimethyl-2propenyl $1-O-{\beta}-D-glucopyranoside$, ethyl ,${\beta}-D-glucopyranoside$, 5-(hydroxymethyl)-2-furfur-aldehyde and uridine. Uridine exhibited inhibition effect of 79% on platelet aggregation at the concentration of$5\;{\mu}g/ml$.