• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
• /
• v.28 no.2
• /
• pp.79-83
• /
• 2017

Neurodegenerative diseases such as Parkinson's disease and amyotrophic lateral sclerosis may induce impairment of speech motor system. This review discusses the characteristics of dysarthria and symptom management for these conditions. Given the progressive nature of the neurodegenerative diseases, speech-language pathologists must be aware of appropriate augmentative and alternative communication equipment at the early stage of the disease course. Patients with neurodegenerative diseases can maintain functional communication with augmentative and alternative communication supports.

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
• /
• v.7 no.1
• /
• pp.5-10
• /
• 1996

From October 1991 to June 1995, 4 medialization thyroplasties and I arytenoid adduction were simultaneously performed with the thyroid surgery when the unilateral recurrent laryngeal nerve was paralyzed before or during thyroidectomy. Four cases were papillary carcinoma with direct invasion to the unilateral recurrent laryngeal nerve, and one case was huge adenomatous goiter and the recurrent laryngeal nerve was incidentaly cut. Hoarseness was present preoperatively with mean duration of 15 months and aspiration was also present in three cases. After phonosurgery, voice was improved in 4 out of 5 cases and aspiration subsided in 2 out of 3 cases. In one case, hoarseness continued after total thyroidectomy and thyroplasty type I and the arytenoid adduction with planned due to posterior glottic gap of 2mm. We suggest that the thyroplasty type I or arytenoid adduction are primary phonosurgical procedures which ran be performed concomitantly with neck surgeries in the patients with paralysis of the unilateral recurrent laryngeal or vagus nerve damage during neck surgeries.

• Proceedings of the KOR-BRONCHOESO Conference
• /
• 1977.06a
• /
• pp.8.1-8
• /
• 1977

Papilloma of the larynx can occur in infants and adults and the tumor is pathologically benign but clinically takes malignant course due to recurrence or malignant change. The authors experienced a case of papilloma of larynx which occured in his infancy and was treated several times surgically due to recurrence but spread to trachea and lung and finally lead to death with malignant change. We here report the case with the case with pt's hospital course, autopsy findings and it's literature consideration.

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
• /
• v.29 no.2
• /
• pp.70-75
• /
• 2018

The office-based, un-sedated vocal fold injection laryngoplasty has re-emerged in the past decade as an appealing alternative to microsuspension laryngoscopic procedure which is conducted under general anesthesia. The trend toward vocal fold injection laryngoplasty in an in-office setting was possible due to technological evolution for visualization and new injection materials. However, invisibility of the injection needle has been the main shortcomings of cricothyroid approach. The purpose of this review is to provide an up-to-date review of office-based, trans-cricothyroid membrane approach injection laryngoplasty technique under local anesthesia and efforts made to increase the preciseness of amount and location of the injected materials in the management of glottic insufficiency. A review of variable efforts undertaken to maximize the result of cricothyroid approach by technically increasing accuracy of the location of needle tip was done. With the proper patient selection and utilization of the new technologies, office-based and un-sedated vocal fold injection laryngoplasty via cricothyroid approach can be redeem as a main-stay in the management of glottic insufficiency, such as vocal fold paralysis, vocal fold paresis, vocal fold atrophy and vocal fold scar.

• Proceedings of the KSLP Conference
• /
• 1996.11a
• /
• pp.97-97
• /
• 1996

저자들은 1994년 1월부터 1996년 8월까지 과대비성(hypernasality)을 주소로 영동세브란스병원 이비인후과를 내원하여 상저부 인두피판(superior based pharyngeal flap) 혹은 후인두벽 증대(posterior pharyngeal wall augmentation) 시행받은 환자 20명을 대상으로 수술 전후의 치료결과를 판정하였다. 수술 전후의 치료결과는 2명의 이비인후과의사와 1명의 언어치료사가 구강을 통한 내시경 적검사와 음성평가를 동시에 시행함으로써 판정하였다. (중략)

• Proceedings of the KSLP Conference
• /
• 2003.11a
• /
• pp.215-218
• /
• 2003

발성치료는 약400여년간 내려오고 있는 성악발성법 (벨칸토 발성)을 이용하여 음성을 교정하고 치료하는 방법으로 과학적이고 의학적으로 인정된 방법을 통하여 음성을 교육하고 교정하는 약물적이고 비 수술적인 치료 방법이다. 음성크리닉검사 1) 공기역학검사(Phonatory function analyzer test) 2) 최대발성지속시간(Maximum phonation time) 3) 컴퓨터 음성검사(Dotor speech. MDVP) 4) 듣기평가 5) 내시경검사(Stroboscopy) 6) 전기성문파형검사(EGG) 7) 호흡근력검사. (MIP. MEP. 등)및 호흡검사(FVC. FEVI. PF. 등) 8) 음성전문의사의 확진 후 발성치료권유 (중략)

• 대한두경부종양학회:학술대회논문집
• /
• 1990.11a
• /
• pp.40.1-40.1
• /
• 1990

• Proceedings of the KSLP Conference
• /
• 1998.11a
• /
• pp.194-194
• /
• 1998

성대내전이 불완전하거나 양측 성대간의 간격이 넓은 경우 애성이나 흡인의 문제를 해결하기 위하여 과거에는 paraffin, teflon, bovine collagen 등을 성대에 주입하여 왔으나 이물반응이나 육아종의 형성 둥이 문제가 되고 있어, 최근에는 자신의 지방이나 피부에서 추출한 교원질을 이용한 연구 및 사례가 보고되고 있다. 그 중 자가지방은 시술이 간편하고, 비용이 적게 드는 장점이 있으나, 흡수율이 높다는 문제점이 지적되고 있다. (중략)

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
• /
• v.12 no.1
• /
• pp.46-54
• /
• 2001

Background and Objectives : Nitric oxide(NO) is a short-lived molecule with messenger and cytotoxic functions in nervous, cardiovascular, and immune systems. Among the three distinct NOS isoforms, the neuronal isoform is expressed in small, discrete neuronal populations of CNS and PNS. Axonal injury in adult animals results in a dramatic NOS up-regulation in many types of central and peripheral neurons which normally lack the enzyme or express it only at very low levels. In previous study, we confirmed the efficacy of PEMS on the early functional recovery in rats with surgically transected and reanastomosed recurrent laryngeal nerve. Therefore, after we obtained functionally recovered rats using PEMS in this study, we studied to evaluate the expression of nNOS through the analysis of the difference between functional recovery group and non-recovery group in the recurrent laryngeal nerve. Materials and Method : Using 84 healthy male Sprague-Dawley rats, transections and primary anastomosis were performed on their left recurrent laryngeal nerves. Rats were then randomly assigned to 2 groups. The rats in group A(n=42) received PEMS by placing them in custom cages equipped with Helm-holz coils(3 hr/day, 5 days/wk, for 12 wk). The rats in group B(n=42) were handled the same way as the group A, except that they did not receive PEMS. Laryngovideoendoscopy was performed before and after surgery and followed up weekly. Laryngeal EMG was obtained in both PCA and TA muscles. Immunohistochemisty staining using monoclonal anti-neuronal nitric oxide synthase(nNOS) antibody was performed to detect nNOS in recurrent laryngeal nerve and nodose ganglion. Results : 20 rats(63%) in group A and 5 rats(17%) in the group B showed recovery of vocal fo1d motion. The number of NOS-positive cells was increased in functionally-recovered rats. NOS-staining intensity was reduced 12 weeks after nerve injury. The difference between PEMS group and non-stimulated group was not found. Conclusion : This study shows that nNOS may exert a beneficial effect on nerve regeneration and functional repair.

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
• /
• v.12 no.2
• /
• pp.126-132
• /
• 2001

Background and Objectives : Signal traduction through phospholipase C(PLC) participate in the regulation of cell growth and differentiation. Growth factors bind to their receptors and thereby induce tyrosine phophorylation of the phospholipase C-${\gamma}$1(PLC-${\gamma}$1). PLC-${\gamma}$1 is a substrate for several receptor tyrosine kinases and its catalytic activity is increased by tyrosine phosphorylation. Tyrosine kinase phosphorylation of PLC-${\gamma}$1 stimulates PLC activation and cell proliferation. However the signal transduction pathway and the significance of PLC in injured recurrent laryngeal nerve regeneration is unknown. Therefore after we obtained fuctionally recovered rats using PEMF in this study, we attempt to provide some evidence that PLC plays a role in nerve regeneration itself and regeneration related to PEMF through the analysis of the difference between fucntional recovery group and non-recovery group in the recurrent laryngeal nerve. Materials and Method : Using 32 healthy male Sprague-Dawley rats, transections and primary anastomosis were performed on their left recurrent laryngeal nerves. Rats were then randomly assigned to 2 groups. The experimental group(n=16) received PEMS by placing them in custom cages equipped with Helm-holz coils(3hr/day, 5days/wk, for 12wk). The control group(n=16) were handled the same way as the experimental group, except that they did not receive PEMS. Laryngo-videoendoscopy was performed before and after surgery and followed up weekly. Laryngeal EMG was obtained in both PCA and TA muscles. Immunohistochemisty staining and Western blotting analysis using monoclonal antibody was performed to detect PLC-${\gamma}$1 in recurrent laryngeal nerve and nodose ganglion. Results : 10 rats(71%) in experimental group and 4 rats(38%) in the control group showed recovery of vocal fold motion. Functionally-recoverd rats show PLC-${\gamma}$1 positive cells in neuron and ganglion cells after 12 weeks from nerve injury. Conclusion : This study shows that PLC1-${\gamma}$ involved in singnal trasduction pathway in functinal recovery of injured recurrent laryngeal nerve and PEMF enhance the functional recovery by effect on this molecule.