• Proceedings of the Mineralogical Society of Korea Conference
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• 2003.05a
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• pp.84-85
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• 2003

소백산육괴의 동부에 분포하는 영양-울진지역의 선캠브리아기 변성암류는 평해층, 기성층, 원남층, 평해화강편마암, 하다우백질화강편마암 등으로 구성되어 있다(김옥준 외, 1963). 그러나, 최근 김남훈 외(2001, 2002)은 야외조사연구와 암석학적 및 지구화학적 연구를 통하여 주로 변성화산암류로 기재되었던 기성층은 변성화산암류가 아니라 평해층과 원남층에서 산출되는 화강암질편마암과 각섬암 기원의 변성암류가 연성전단변형을 받아 형성된 압쇄암 내지 초압쇄암으로 되어 있고, 기존의 기성층은 변성화산암류와 같이 성분상으로 구분되는 별개의 층이 아닌 구조적으로 만들어진 연성전단대의 중심부일 가능성을 시사한 바가 있다. 본 연구는 연성전단대의 연장성 및 연성전단대 형성과 관련된 지구조운동의 특성을 파악하고, 중첩된 변형구조들의 선후관계로부터 영양-울진지역 선캠브리아기 변성암류에 대한 변형작용사를 규명하기 위해 기성층의 분포지를 중심으로 이 지역 선캠브리아기 변성암류에 대한 상세한 야외지질조사를 실시하였다. 그 결과, 예천(북후면-평은면)지역을 통과하여 봉화 부근에서 동북동-서남서 방향이 동-서 방향으로 전환하여 장군봉지역까지 연장되는 것으로 알려져 있는 우수 주향 이동성 예천전단대(KIGAM, 1995; 강지훈 외 1997; 강지훈, 2000; 강지훈과 김형식, 2000)는 영양-울진지역까지 연장됨이 확인된다. 또한, 영양-울진지역의 선캠브리아기 변성암류에는 연성전단변형 이전에 적어도 한 번의 습곡작용과 이후에 적어도 두 번의 습곡작용이 인지된다. 각 변형단계별 특징적인 구조요소를 요약하면 다음과 같다. D1 변형: 편마면 내지 편리(S0)가 습곡되어 형성된 F1 습곡은 동-서 방향의 준 수평적인 습곡축을 갖는 뿌리 없는 등사습곡 형태로 인지된다. 양 날개부의 S0 엽리는 F1 습곡축면(S1)으로 완전히 전위된 하나의 엽리(S0-1)로 나타나고, S0-1 엽리는 이 지역의 광역엽리로 인지된다. S0-1 광역엽리는 구성암류의 대상 분포 방향과 유사한 서북서 주향에 북쪽으로 중각 경사하는 집중된 방향성을 보이며 분산되어 나타난다. D2 변형: 변형구조로는 신장선구조, 압쇄구조면, 비대칭습곡 등으로 인지된다. 신장선구조는 S0-1 엽리면상에서 주로 신장된 석영(집합체)과 장석(집합체)들의 정향배열에 의해 정의되고, S0-1 엽리의 주향 방향으로 저각으로 침강하는 집중된 방향성을 보이며 분산되어 나타난다. 신장선구조에 평행하고 S0-1 엽리에 수직한 단면에서는 상부-동쪽-이동의 우수주향 이동성 연성 전단운동감각을 지시하는 구조요소들이 다량 관찰된다. 연성전단변형에 의해 형성된 압쇄구조면은 전단엽리와 압쇄엽리에 각각 해당하는 C면과 S면 등이 인지된다. 전단엽리 C면은 S0-1 광역엽리와 거의 일치하고, 압쇄엽리 S면은 F2 비대칭습곡의 축면엽리와 거의 일치한다. S0-1 엽리를 습곡시키는 F2 비대칭습곡은 S0-1 엽리를 전단면으로 하여 상부-동쪽-이동 전단운동에 의해 형성된 밀착습곡 형태로 인지된다. F2 습곡축은 북동 방향으로 중각 내지 저각 침강하고 F1 습곡축과는 65$^{\circ}$-75$^{\circ}$ 범위의 사이각을 이룬다. F2 습곡축면은 동북동 주향에 북쪽으로 중각으로 경사하고 F1 습곡축면과는 20$^{\circ}$-40$^{\circ}$ 범위의 사이각을 이룬다. D3 변형. S0-1 엽리와 압쇄구조면 등을 습곡시키는 F3 습곡은 준 수평적인 습곡축과 습곡축면을 갖는 개방 횡와습곡의 형태로 인지된다. D4 변형: F4 습곡은 비대칭 공역성 킹크습곡, 공역성 충상단층에 수반되어 나타나는 드래그습곡, 대칭 개방 직림습곡 등의 다양한 습곡 형태로 인지된다. 이들 F4 습곡의 축면엽리는 일반적으로 동-서 주향에 남쪽과 북쪽으로 경사한다. 그 경사각은 비대칭 공역성 킹크습곡(저각), 드래그습곡(중각), 대칭 개방 직립습곡(고각) 순으로 고각을 이룬다. F4 습곡축은 동쪽과 서쪽으로 저각 침강하는 집중된 방향성을 보인다. 공역성 충상단층은 동-서 주향에 남쪽과 북쪽으로 경사하는 단층면과 상부가 북쪽과 남쪽으로 충상하는 운동상을 보인다. 드래그습곡의 축면엽리는 이러한 공역성 충상단층운동의 전단압축방향에 수직으로 발달한다. 이러한 D4 변형구조는 남-북 방향의 압축 지구조 환경하에서 형성된 것으로 고찰된다.

• Journal of the Mineralogical Society of Korea
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• v.20 no.4
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• pp.303-311
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• 2007

The consumption of artificially crushed sands exceeds more than 30 percent of the domestic sand supply in South Korea, and its rate is still increasing. For the manufacture of crushed sand granites and granitic gneisses are preferred, fine fractions (i.e. sludge, particles finer than 63 microns) are removed by use of flocculation agents, and its amount occupy about 15 wt%. The sludges consist of quartz, feldspars, micas, chlorite/vermiculite, kaolinites, smectites and occasionally calcite. Among the clay minerals micas are usually predominant, and $14{\AA}$ minerals, kaolinites and smectites are rather scarce. Jurassic granites usually contain more kaolinites and smectites than those of Cretaceous to Tertiary granites, probably due to longer geologic ages. On the other hand, sludge from Precambrian gneiss does not contain kaolinites and smectites. Chemical analyses for the granites and their sludges show rather clear differences in most of major chemical components. Except for $SiO_2,\;Na_2O\;and\;K_2O$, all other components represent rather clear increase. Decrease of $SiO_2$ content is attributed to the relative decrease of quartz in the sludges. And the $Na_2O decrease is caused by a relatively stronger weathering property of albite compared to Ca plagioclase. The $K_2O$ content shows rather small differences throughout the whole samples. The increases of $Al_2O_3$ and other major components resulted from weathering processes and most of colored components are also concentrated in the sludges. Particle size analyses reveal that the sludges are categorized as sandy loams in a sand-silt-clay triangular diagram. The sludge is now classified as industrial waste because of its impermeability, and this result was also confirmed by rather higher hydraulic conductivities. For the environmental problems, and accomplishing effective sand manufacture, more fresh rocks with little weathering products must be chosen.

• Korean Journal of Microbiology
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• v.53 no.2
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• pp.83-96
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• 2017

A constructed sea stream in Yeongdo, Busan, Republic of Korea is mostly static due to the lifted stream bed and tidal characters, and receives domestic wastewater nearby, causing a consistent odor production and water quality degradation. Bioaugmentation of a microbial consortium was proposed as an effective and economical restoration technology to restore the polluted stream. The microbial consortium activated on site was augmented on a periodic basis (7~10 days) into the most polluted site (Site 2) which was chosen considering the pollution level and tidal movement. Physicochemical parameters of water qualities were monitored including pH, temperature, DO, ORP, SS, COD, T-N, and T-P. COD and microbial community analyses of the sediments were also performed. A significant reduction in SS, COD, T-N, and COD (sediment) at Site 2 occurred showing their removal rates 51%, 58% and 27% and 35%, respectively, in 13 months while T-P increased by 47%. In most of the test sites, population densities of sulfate reducing bacterial (SRB) groups (Desulfobacteraceae_uc_s, Desulfobacterales_uc_s, Desulfuromonadaceae_uc_s, Desulfuromonas_g1_uc, and Desulfobacter postgatei) and Anaerolinaeles was observed to generally decrease after the bioaugmentation while those of Gamma-proteobacteria (NOR5-6B_s and NOR5-6A_s), Bacteroidales_uc_s, and Flavobacteriales_uc_s appeared to generally increase. Aerobic microbial communities (Flavobacteriaceae_uc_s) were dominant in St. 4 that showed the highest level of DO and least level of COD. These microbial communities could be used as an indicator organism to monitor the restoration process. The alpha diversity indices (OTUs, Chao1, and Shannon) of microbial communities generally decreased after the augmentation. Fast uniFrac analysis of all the samples of different sites and dates showed that there was a similarity in the microbial community structures regardless of samples as the augmentation advanced in comparison with before- and early bioaugmentation event, indicating occurrence of changing of the indigenous microbial community structures. It was concluded that the bioaugmentation could improve the polluted water quality and simultaneously change the microbial community structures via their niche changes. This in situ remediation technology will contribute to an eco-friendly and economically cleaning up of polluted streams of brine water and freshwater.

• Korean Journal of Microbiology
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• v.54 no.1
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• pp.9-17
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• 2018

To investigate the role of bkdR, sigL, yplP, and des genes which were known to be involved in fatty acid synthesis and sensitive at low temperature, deletion mutants of Bacillus subtilis CU1065 and JH642 were constructed. To determine the low temperature sensitivity of these genes, we compared the growth curves of cells at $37^{\circ}C$ and $15^{\circ}C$. At $37^{\circ}C$, wild type and deletion mutants showed almost similar growth but only bkdR deletion strain at $15^{\circ}C$ showed very slow growing compared with wild type. At $15^{\circ}C$ sigL and yplP deletions were somewhat slower or similar to those of wild type strain. Double and triple mutants for bkdR, sigL, yplP deletions were constructed and grown at $20^{\circ}C$ in LB agar to investigate cold sensitive growth. Double or triple deletions including bkdR deletion showed cold sensitive growing. In order to identify more clearly cold sensitive growth, the experiments were carried out under cold shock conditions in which the temperature was lowered from $37^{\circ}C$ to $15^{\circ}C$ at the point of 0.4 optical densities at 600 nm. In these cold shock experiments, only bkdR deletion showed significantly lower growing and additional des deletion increases cold sensitivity. The bkdR activates the bkd operon, which catabolized isoleucine, valine and leucine, amino acids and produce precursors for the synthesis of branched fatty acids. At cold shock growing of bkdR deletion strain, isoleucine recovered cold sensitivity of bkdR deletion but valine did not restore cold sensitivity. Isoleucine is used as a precursor for the synthesis of anteiso-branched fatty acids. On the other hand, valine is used as a precursor for the synthesis of iso-branched fatty acids. This indicates that anteiso-branched fatty acid plays an important role at the cold shock condition.

• Tunnel and Underground Space
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• v.22 no.4
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• pp.266-275
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• 2012

In this study, a method is devised to implement a supercritical $CO_2$ ($scCO_2$) injection environment on a laboratory scale and to investigate the effects of $scCO_2$ on the properties of rock specimens. Specimens of shale and sandstone normally constituting the cap rock and reservoir rock, respectively, were kept in a laboratory reactor chamber with $scCO_2$ for two weeks. From this stage, a chemical reaction between rock surface and the $scCO_2$ was induced. The effect of saline water was also investigated by comparing three conditions ($scCO_2$-rock, $scCO_2-H_2O$-rock and $scCO_2$-brine(1M)-rock). Finally, we checked the changes in the properties before and after the reaction by destructive and nondestructive testing procedures. The swelling of shale was a main concern in this case. The experimental results suggested that $scCO_2$ has a greater effect on the swelling of the shale than pure water and brine. It was also observed that the largest swelling displacement of shale occurred after a reaction with the $H_2O-scCO_2$ solution. The results of a series of the destructive and nondestructive tests indicate that although each of the property changes of the rock differed depending on the reaction conditions, the $H_2O-scCO_2$ solution had the greatest effect. In this study, shale was highly sensitive to the reaction conditions. These results provide fundamental information pertaining to the stability of $CO_2$ storage sites due to physical and chemical reactions between the rocks in these sites and $scCO_2$.

• The Korean Journal of Petroleum Geology
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• v.10 no.1_2 s.11
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• pp.23-33
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• 2004

The Lago Sofia conglomerate in southern Chile is a lenticular unit encased within mudstone-dominated, deep-sea successions (Cerro Toro Formation, upper Cretaceous), extending from north to south for more than $120{\cal}km$. The Lago Sofia conglomerate is a unique example of long, gravelly deep-sea channels, which are rare in the modern environments. In the northern part (areas of Lago Pehoe and Laguna Goic), the conglomerate unit consists of 3-5 conglomerate bodies intervened by mudstone sequences. Paleocurrent data from these bodies indicate sediment transport to the east, south, and southeart. The conglomerate bodies in the northern Part are interpreted as the tributary channels that drained down the Paleoslope and converged to form N-S-trending trunk channels. In the southern part (Lago Sofia section), the conglomerate unit comprises a thick (> 300 m) conglomerate body, which probably formed in axial trunk channels of the N-5-trending foredeep trough. The well-exposed Lago Sofia section allowed for detailed investigation of sedimentary facies and large-scale architecture of the deepsea channel conglomerate. The conglomerate in Lago Sofia section comprises stratified conglomerate, massive-to-graded conglomerate, and diamictite, which represent bedload deposition under turbidity currents, deposition by high-density turbidity currents, and muddy debris flows, respectively. Paleocurrent data suggest that the debris flows originated from the failure of nearby channel banks or slopes flanking the channel system, whereas the turbidity currents flowed parallel to the orientation of the overall channel system. Architectural elements produced by turbidity currents represent vertical stacking of gravel sheets, lateral accretion of gravel bars, migration of gravel dunes, and filling of channel thalwegs and scoured hollows, similar to those in terrestrial gravel-bed braided rivers. Observations of large-scale stratal pattern reveal that the channel bodies are offset stacked toward the east, suggestive of an eastward migration of the axial trunk channel. The eastward channel migration is probably due to tectonic tilting related to the uplift of the Andean protocordillera just west of the Lago Sofia deep-sea channel system.

• Pediatric Infection and Vaccine
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• v.24 no.2
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• pp.95-101
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• 2017

Purpose: Acute bacterial gastroenteritis (ABG) can cause more severe symptoms than acute viral gastroenteritis in children. This study was aimed at determining the etiologic trends and to examine the clinical characteristics of ABG in children. Methods: We sent stool samples from the children with acute gastroenteritis who were treated at a secondary hospital located in Seoul, Korea between January 2011 and December 2014 to Seoul Metropolitan Government Research Institute of Public Health and Environment to find the causative organisms. Clinical characteristics of patient were analyzed through a medical records review. Results: Out of 664 stool samples, 183 (27.6%) yielded bacterial pathogens. Staphylococcus aureus was the most common bacterial pathogen, found in 72 cases (39.3%), even though it was only tested for since 2012. The monthly isolation rate was the highest (24.6%) in August. The isolation rate of Campylobacter spp. by patient's age group was high (16.7%) in the 12- to 18-year-age group (P=0.04). In patients with bloody stool, Campylobacter spp. was the most commonly isolated (31.0%, P=0.04). When comparing C-reactive protein, the Salmonella spp.- or Campylobacter spp.-isolated group showed higher values than the S. aureus- or pathogenic Escherichia coli-isolated group ($5.7{\pm}0.6mg/dL$ vs. $2.1{\pm}0.3mg/dL$, P<0.01). Conclusions: S. aureus, Salmonella spp., pathogenic E. coli, and Campylobacter spp. were important pathogens of ABG among children. Considering the differences in pathogens found according to age, a clinical symptom and inflammation index might be helpful in assuming the causative organism.

• Journal of Life Science
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• v.26 no.7
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• pp.835-846
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• 2016

Chemo-resistance is the biggest issue of effective cancer therapy. ABCG2 is highly correlated with multi-drug resistance, and represent a typical phenotype of multiple cancer stem-like cells. Accumulating evidence recently reported that oncolytic viruses represent a new strategy for multiple aggressive cancers and drug resistant cancers including cancer stem cell-like cells and ABCG2 expressing cells. In this study, we generated an evolutionally engineered vaccinia virus, SLJ-496, for drug-resistant cancer therapy. We first showed that SLJ-496 treatment enhanced tumor affinity using cytopathic effect assay, plaque assay, as well as cell viability assay. Next, we clearly demonstrated that in vitro SLJ-496 treatment represents significant cytotoxic effect in multiple cancers including colorectal cancer cells (HT-29, HCT-116, HCT-8), gastric cancer cells (AGS, NCI-N87, MKN-28), Hepatocellular carcinoma cells (SNU-449, SNU-423, SNU-475, HepG2), as well as mesothelioma cell (NCI-H226, NCI-H28, MSTO-221h). Highly ABCG2 expressing HT-29 cells represent cancer stem like phenotype including stem cell marker expression, and self-renewal bioactivities. Interestingly, we demonstrated that in vitro treatment of SLJ-496 showed significant cytotoxicity effect, as well as viral replication capacity in ABCG2 overexpressing cell. In addition, we also demonstrated the cytotoxic effect of SLJ-496 in Adriamycin-resistant cell lines, SNU-620 and ADR-300. Taken together, these findings provide us a pivotal clue that cancer therapy using SLJ-496 vaccinia virus might be new therapeutic strategy to overcome ABCG2 expressing cancer stem-like cell and multiple chemo-resistance cancer cells.

• Communications of Mathematical Education
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• v.23 no.3
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• pp.735-760
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• 2009

Most of every teachers' life is occupied with his or her instruction, and a classroom is a laboratory for mutual development between teacher and students also. Namely, a teacher's professionalism can be enhanced by circulations of continual reflection, experiment, verification in the laboratory. Professional development is pursued primarily through teachers' reflective practices, especially instruction practices which is grounded on $Sch\ddot{o}n's$ epistemology of practices. And a thorough penetration about situations or realities and an exact understanding about students that are now being faced are foundations of reflective practices. In this study, at first, we explored the implications of earlier studies for discussing a teacher's practice. We could found two essential consequences through reviewing existing studies about classroom and instructions. One is a calling upon transition of perspectives about instruction, and the other is a suggestion of necessity of a teachers' reflective practices. Subsequently, we will talking about an instance of a middle school mathematics teacher's practices. We observed her instructions for a year. She has created her own practical knowledges through circulation of reflection and practices over the years. In her classroom, there were three mutual interaction structures included in a rich expressive environments. The first one is students' thinking and justifying in their seats. The second is a student's explaining at his or her feet. The last is a student's coming out to solve and explain problem. The main substances of her practical know ledges are creating of interaction structures and facilitating students' spontaneous changes. And the endeavor and experiment for diagnosing trouble and finding alternative when she came across an obstacles are also main elements of her practical knowledges Now, we can interpret her process of creating practical knowledge as a process of self-directed professional development when the fact that reflection and practices are the kernel of a teacher's professional development is taken into account.

• The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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• v.18 no.4
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• pp.214-226
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• 2013

To understand the changing patterns in phytoplankton communities, we conducted 12 surveys along the Nakdong River, its estuary, and adjacent coastal areas between January 2011 and October 2012 (during the period of barrage construction and sediment dredging). Monthly precipitation ranged from 0 to 502 mm during the survey period, and salinity ranged between 0.1 psu and 0.3 psu in the Nakdong River, regardless of the depth, indicating no seawater influence, while salinity showed large seasonal fluctuations in the estuarine and coastal station, ranging from 0.1 psu to 34.8 psu. A total of 402 phytoplankton species were identified, 178 species from the river and 331 species from the estuary and coastal areas. Phytoplankton standing crop increased in 2012 compared to that in 2011, and was found to be highest in the river, followed by the estuary and coastal areas. Among the top 20 species in frequency of occurrence and dominance, Stephanodiscus spp., Aulacoseira granulata, and Aulacoseira granulata var. angustissima and Pseudo-nitzschia spp. were important species along the river-estuary-coastal areas. Diatoms were the major taxonomic group inhabiting the Nakdong river-estuary-coastal areas. A comparison of seasonal dominant phytoplankton species revealed a slight decrease over the years, from 13 species in 2011 to 10 species in 2012. However, no significant difference was found in the diversity of phytoplankton species between the two survey years, although lightly greater diversity was observed in the coastal areas than in the river and estuary. Cluster analysis with community composition data revealed that the community structure varied significantly in 2011 depending on the time of survey, while in 2012, it hardly showed any variation and was simpler. An increase in the phytoplankton standing crop, fewer dominant species, and simpler community structure in 2012 compared to those in 2011 are probably due to the rapid environmental changes along the Nakdong River. To investigate these ecological relationships, it is necessary to conduct further studies focusing on integrated analyses of biocenosis, including phytoplankton with respect to the changes in nutrient distribution, variation of freshwater discharge, and effect area of freshwater in the Nakdong estuary and adjacent coastal areas.