• Journal of Life Science
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• v.9 no.2
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• pp.201-206
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• 1999

Nitric oxide(NO) is a potent and selective pulmonary artery vasodilator. Erythropoietin(EPO) is produced in the kidney in response to reduced oxygen availability. In this study, blood samples were collected for determination of NO and EPO concentrations in 18 normal newborns and 16 newborns with respiratory distress syndrome(RDS). Serum was measured by Ding's method for NO concentration and by enzyme-linked immunosorbant assay for EPO concentration. Nitric ion concentration in serum was 14.9$\pm$3.2 $\mu$M in normal control group and 12.8$\pm$3.3 $\mu$M in RDS group. EPO concentration in serum was 16.2$\pm$3.4 mU/ml in normal control group and 21.2$\pm$5.4 mU/ml in RDS group. These results show the decrease of NO and increase of EPO in RDS newborn patients in comparison with normal newborns. Such imbalances may contribute to the development of several clinical symptoms.

• The Journal of the Convergence on Culture Technology
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• v.7 no.1
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• pp.576-581
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• 2021

In the post-epidemic era, COVID-19 has not yet been fully controlled. Wearing masks is still the main means of epidemic prevention, and the negative effects brought by masks continue to continue. Wearing a mask for a long time can cause two problems. The first problem is hypoxia, and the other is an increase in psychological stress. To reduce the negative impact of masks, this paper proposes a new breathing mode. It is the "Umm~" vocal breathing mode, which simultaneously solves the two problems of hypoxia and increased stress. This paper explores the reasons why new breathing patterns can relieve stress. Explains the relationship between HRV and stress index and uses SDNN as an indicator to detect stress index to confirm the effectiveness of this breathing pattern. Experimental results prove that the "Umm~" vocal breathing mode can not only relieve the stress induced by wearing a mask. And when not wearing a mask, it can also be used to relieve daily stress. This method that anyone can easily implement should be more popularized.

• Journal of Yeungnam Medical Science
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• v.10 no.1
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• pp.1-17
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• 1993

고빈도 환기법은 최근에 개발되어 임상에 응용되면서 호흡생리학, 마취학, 집중치료의 학등의 분야에서 호흡부전의 새로운 치료법으로 관심이 집중되고 있는 환기법이다. 현재까지 고빈도 환기법중 고빈도 양압 환기와 제트 환기는 비교적 많은 연구가 되고 있고 임상적으로 사용되고 있으나 고빈도 진동 환기법은 제한적으로 사용되고 있다. 앞으로 고빈도 진동 환기법에 대해서도 더 많은 연구가 되어야 할 것이다. 또한 최근 개발되고 있는 고빈도 흉벽 진동 환기와 체표면 진동 환기에도 관심을 기울이면 호흡부전 환자의 치료에 바람직한 새로운 환기법이 될 수 있을 것으로 기대된다. 현재 고빈도 환기법의 몇몇 적용형태는 기관지-늑막루등의 폐압손상으로 인한 병변의 치료외에도 기관수술, 흉부수술, 뇌수술에서 수술부위의 움직임을 최소화시키면서 충분한 가스교환율 이룩할 수 있어서 효과적으로 이용되고 있다. 그러나 응급심폐소생술, 폐쇄성 폐질환, 성인 또는 영아 호흡곤란증후군등과 같은 질환에서의 적용은 더 규명되어져야겠다. 고빈도 환기법의 여러가지 문제점중 적절한 환기빈도의 결정, 충분한 습도를 공급하는 장치, 고빈도 환기의 정확한 감시장치의 개발등은 앞으로 우선적으로 해결해야 할 문제점이다. 또한 임상에 더욱 효과적으로 응용될 수 있는 새로운 환기법이 되기 위해서는 고빈도 환기법의 호흡생리와 안정성등에 관한 연구도 병행되어야겠다.

• The Journal of Korean Society for Radiation Therapy
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• v.25 no.1
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• pp.49-55
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• 2013

Purpose: Respiratory Gated Radiation Therapy (RGRT) has been carried out using RPM (Real-time Position Management) Respiratory Gating System (version 1.7.5, varian, USA) in Asan Medical Center. This study was to analyze and evaluate the accuracy of Respiratory Gated Radiation Therapy (RGRT) according to variation of respiration. Materials and Methods: Making variation of respiration using Motion Phantom:QUASAR Programmable Respiratory Motion Phantom (Moudus Medical Device Inc. CANADA) able to adjust respiration pattern randomly was varying period, amplitude and baseline by analyze 50 patient's respiration of lung and liver cancer. One of the variations of respiration is baseline shift gradually downward per 0.01 cm, 0.03 cm, 0.05 cm. The other variation of respiration is baseline shift accidently downward per 0.2 cm, 0.4 cm, 0.6 cm, 0.8 cm. Experiments were performed in the same way that is used RPM Respiratory Gating System (phase gating, usually 30~70% gating) in Asan Medical Center. Results: It was all exposed radiation under one of the conditions of baseline shift gradually downward per 0.01 cm, 0.03 cm, 0.05 cm. Under the other condition of baseline shift accidently downward per 0.2 cm, 0.4 cm, 0.6 cm, 0.8 cm equally radiation was exposed. Conclusion: The variations of baseline shifts didn't accurately reflect on phase gating in RPM Respiratory Gating System. This inexactitude makes serious uncertainty in Respiratory Gated Radiation Therapy. So, Must be stabilized breathing of patient before conducting Respiratory Gated Radiation Therapy. also must be monitored breathing of patient in the middle of treatment. If you observe considerable changes of breathing when conducting Respiratory Gated Radiation Therapy. Stopping treatment immediately and then must be need to recheck treatment site using fluoroscopy. If patient's respiration rechecked using fluoroscopy restabilize, it is possible to restart Respiratory Gated Radiation Therapy.

• Journal of Biomedical Engineering Research
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• v.16 no.3
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• pp.353-358
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• 1995

The impedance pneumography which is widely used in monitoring respiration is simple to use and noninvasive, but it is sensitive to motion artifacts and insensitive to detect obstructive apnea. A 3-channel respiratory inductive plethysmography (RIP) developed in this study detects inductance change of the inductance band induced by cross-sectional area change of thorax or abdomen as one breathes. It was confirmed that RIP was less sensitive to various motion artifacts but more sensitive to detection of obstructive apnea than impedance pneumography.

• Proceedings of the KIEE Conference
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• 2008.10b
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• pp.478-479
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• 2008

본 연구에서는 비접촉 방식으로 심박과 호흡을 측정하기 위해 2.4GHz 대역에서 동작하는 도플러 레이더 센서와 베이스밴드 모듈로 구성된 도플러 레이더 시스템을 설계하고 그 성능을 평가하였다. 설계된 도플러 레이더 시스템은 심폐활동에 의한 흉부 표면의 움직임에 의해 반사되는 레이더의 위상변화를 이용하여 심폐 활동을 측정한다. 도플러 레이더 센서의 출력은 베이스 밴드 모듈의 전처리 필터부, 증폭부, 오프셋 조정부를 통과하여 호흡과 심박 신호로 분리된다. 분리된 생체신호는 기존의 생체신호와 상관성을 확인하기 위해 기준신호로 호흡과 심전도를 동시에 측정하여 그 결과를 비교 및 분석하였다. 설계된 도플러 레이더 시스템에서 분리된 호흡 및 심박 신호는 측정 대상의 움직임이 없는 상태에서는 높은 검출률을 보였으며, 도플러 레이더에서 심박과 호흡 신호를 검출한 결과 거리, 호흡과 심박의 변이량, 호흡과 심박대역에 따라 검출률이 영향을 받는다는 것을 알 수 있었다.

• The Journal of Korean Society for Radiation Therapy
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• v.23 no.1
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• pp.13-19
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• 2011

Purpose: It's essential to minimize the tumor motion and identify the exact location of the lesions to achieve the improvement in radiation therapy efficiency during SBRT. In this study, we made the established compression belt to reduce respiratory motion and evaluated the usefulness of clinical application in SBRT. Materials and Methods: We analyzed the merits and demerits of the established compression belt to reduce the respiratory motion and improved the reproducibility and precision in use. To evaluate the usefulness of improved compression belt for respiratory motion reduction in SBRT, firstly, we reviewed the spiral CT images acquired in inspiration and expiration states of 8 lung cancer cases, respectively, and analyzed the three dimensional tumor motion related to respiration. To evaluate isodose distribution, secondly, we also made the special phantom using EBT2 film (Gafchronic, ISP, USA) and we prepared the robot (Cartesian Robot-2 Axis, FARARCM4H, Samsung Mechatronics, Korea) to reproduce three dimensional tumor motion. And analysis was made for isodose curves and two dimensional isodose profiles with reproducibility of respiratory motion on the basis of CT images. Results: A respiratory motion reduction compression belt (Velcro type) that has convenient use and good reproducibility was developed. The moving differences of three dimensional tumor motion of lung cancer cases analyzed by CT images were mean 3.2 mm, 4.3 mm and 13 mm each in LR, AP and CC directions. The result of characteristic change in dose distribution using the phantom and rectangular coordinates robot showed that the distortion of isodose has great differences, mean length was 4.2 mm; the differences were 8.0% and 16.8% each for cranio-caudal and 8.1% and 10.9% each for left-right directions in underdose below the prescribed dose. Conclusion: In this study, we could develop the convenient and efficient compression belt that can make the organs' motion minimize. With this compression belt, we confirmed that underdose due to respiration can be coped with when CTV-PTV margins of mean 6 mm would be used. And we conclude that the respiratory motion reduction compression belt we developed can be used for clinical effective aids along with the gating system.

• Journal of Korean Biological Nursing Science
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• v.6 no.1
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• pp.5-15
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• 2004

목적 : 이 연구는 항암제를 투여받는 여성암환자에서 발반사마사지가 스트레스반응(활력징후, 코티졸)과 면역반응에 미치는 효과를 평가하기 위함이다. 방법 : 11명의 여성암 환자를 임의로 표출한 후 단일군 전후실험설계로 진행하였다. 종속변수는 스트레스 반응으로 활력징후(수축기 혈압, 이완기 혈압, 맥박수, 호흡수)와 혈중 코티졸, 면역반응으로 림프구 아군(CD3, CD4, CD8, CD19)과 자연살세포(NK cells)이며, 독립변수는 발반사마사지이었다. 중재 전후 종속변수의 변화를 보기 위해 Wilcoxon signed rank test를 실시하였다. 결과 : 중재 전에 비해 중재 후 수축기 혈압, 이완기 혈압, 맥박수, 혈중 코티졸치, CD4와 CD19는 유의한 변화를 보였으나 호흡수, CD3, CD8, 그리고 자연살세포는 유의한 변화를 보이지 않았다. 결론 : 이러한 연구결과는 발반사마사지가 항암화학요법을 받는 여성암 환자의 스트레스 호르몬과 면역관련세포에 영향을 보였지만 표본수가 작고 중재가 1회에 그쳤기 때문에 이러한 단점을 보완한 추후연구를 통해 발반사마사지의 효과를 좀더 잘 규명할 수 있을 것이다.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2003.05a
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• pp.514-517
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• 2003

Oxygen supply is one of the most basic things in human body. Breathing is controlled by the lungs' stationary function and the respiratory center which is in the mesulla oblongata. Nothing but, the external breathing that air movement between the lungs and atmosphere and the internal breathing that cellular air movement between the hemoglobin and a single cell. The adult's number of times of the respirations is about 15∼20 per 1 minute, but it depends ages, exercise, temperature, disease, etc. The important thing in detecting the respiration is that doing it in object person's resting time. Detecting the respiration have to be done without attracting any attention of object person. In present using method is detecting the pulse with catching an object person's wrist and observing the object person's movement. In this paper, we propose the mobile respiration detection diagnostic system using ultrasound sensing method that does not be influenced by the inertia error and the pressure error.

• Journal of Naturopathy
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• v.11 no.2
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• pp.116-122
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• 2022

Background: Studies on the effect of abdominal or thoracic breathing therapy on sleep or blood oxygen concentration are still scarce. Purpose: This study was to examine the effect on blood oxygen saturation and pulse variability, changes in the severity of insomnia, changes in wakefulness before sleep, and dysfunctional beliefs and attitudes toward the Korean version of sleep in women in their 50s after healing with abdominal breathing and thoracic breathing. We investigated the effect. Methods: Subjects were investigated before and after the change of breathing (breathing) therapy for 12 weeks, 3 times a week, and 36 breaths perweek. Results: It wa evaluated respiratory healing as having no significance in the pulse rate change. However, oxygen saturation was significant in the experimental group, increasing to 93.60 SpO₂% before the respiratory rally and 96.5 SpO₂% after respiratory recovery (p < .002). In addition, the insomnia severity scale and dysfunctional beliefs about sleep significantly decreased after respiratory rally than before (p < .000). Conclusions: It evaluated that respiratory therapy for the subjects is beneficial to health as it is effective for insomnia, pulse, and oxygen saturation.