• 동의신경정신과학회지
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• 제19권2호
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• pp.223-230
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• 2008

소합향원 (蘇合香元) 가감방(加減方) 정유향기의 진통효과가 투여방법에 따라 어떤 차이가 있는지를 비교, 검토함으로서 본 약재의 새로운 적용방법을 탐색해 보고자 한다. 방법 : 가감소합향원에서 추출한 정유향기를 실험동물을 대상으로 7일간 경구 (50mg/kg, 100mg/kg), 흡입 (매일 3시간씩 1일 2회), 또는 피부도찰 (10mg) 방법으로 투여하여 페닐퀴논-유도 writhing test, 아세트산-유도 writhing test 및 hot-plate test를 실시하였다. 결과 : 가감소합향원 정유향기는 페닐퀴논-유도 writhing test에서는 피부도찰이 가장 효과적 이었으며 그 효과는 양성 대조약물인 아세트아미노펜 보다 약간 더 우수하였다 (p<0.05). 아세트산-유도 writhing test에서도 피부도찰법이 가장 좋은 효과를 나타내었으며 양성대조 약물인 아미노피린보다는 좀 더 좋은 효과를 보여주었다 (p<0.05). 그러나 hot-plate test에서는 경구투여가 가장 좋은 진통효과를 나타내었는데 고용량 (100mg/kg)에서는 양성 대조약물인 아세트아미노펜보다 유의적으로 더 효과적이었으나 저용량 (50mg/kg )에서는 이보다 다소 약하였다. 이상의 연구결과, 가감소합향원의 정유향기는 피부도찰시에는 비특이적 화학자극제인 페닐퀴논이나 아세트산에 의한 통증의 완화에 보다 효과적이며, 경구투여시에는 중추신경계에 영향을 미치는 hot plate에 의한 열자극성 통증에 더 유효함을 의미한다. 결론 : 가감소합향원의 정유향기액은 향기흡입보다는 피부흡수나 경구투여방법으로 진통의 목적으로 응용될 수 있을 것으로 사료된다.

• 생명과학회지
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• 제23권7호
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• pp.933-940
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• 2013

본 연구는 박하(Mentha arvensis) 식물 유래 향료의 향기성분을 구명하고, 향기성분들이 인간의 뇌파에 어떠한 영향을 미치는지를 이해하고자 수행하였다. 초임계추출기를 이용하여 박하 식물(Mentha arvensis L. f. piperascens)로부터 에센셜오일을 얻었으며, 최적 회수율은 $70^{\circ}C$, 200 bar 조건에서 2.38%이었다. 박하 에센셜오일에 함유되어 있는 향기 화합물을HS-SPME/GC-MS로 분석한 결과, 총 32종의 화합물이 검출되었는데 alcohol 류가 6종(67.11%), hydrocarbon 류가 13종(17.05%), ester 류가 9종(11.50%), ketone 류가 2종(7.16%), oxide가 1종(2.77%) 그리고 aldehyde가 1종(0.56%)이었다. 박하 에센셜오일에 함유된 주된 향기 화합물은 (Z,Z,Z)-9,12,15-octadecatrien-1-ol (50.06%), 2-hydroxy-4-methoxyacetophenone (7.50%)과 3,4-dihydro-8-hydroxy-3-methyl-1H-2-benzopyran-1-one (6.60%) 이었다. 총 20명의 피험자(남녀 각 10명)를 대상으로 박하 에센셜오일 향기 흡입 전과 흡입 중에 뇌파분석을 수행한 결과, 향기를 흡입 중에는, 흡입 전과 비교하여, relative fast alpha power spectrum이 유의성 있게 증가하는 반면(p<0.05), gamma power spectrum과 spectral edge frequency 90% 지표는 유의성 있게 감소하는 결과를 얻었다(p<0.05). 본 연구의 결과들은 박하의 향기성분이 정신적 긴장을 완화시킨다는 것을 시사하여 준다.

• 기본간호학회지
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• 제16권3호
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• pp.300-306
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• 2009

Purpose: This study was done to investigate differences between lavender abdominal massage and inhalation on dysmenorrhea, menstrual pain, anxiety, and depression. Methods: This study used a non equivalent quasi-experimental design. Lavender essential oil and almond oil were used in massage and a lavender necklace and artificial perfume necklace in inhalation for female college students. Frequencies, percentages, Chi-square, Fisher's exact test and t-test with the SPSS/WIN 12.0 program were used to analyze the data. Results: Dysmenorrhea was significantly higher inhalation for placebo treatment compared to lavender inhalation (p< .001). There was not significant difference between lavender abdominal massage and inhalation. Conclusion: Lavender abdominal massage and inhalation could be effective methods to reduce dysmenorrhea. However, before lavender abdominal massage and inhalation can be considered as intervention, it is more needed to study of menstrual pain, anxiety and depression.

• 문화기술의 융합
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• 제4권2호
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• pp.171-178
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• 2018

본 연구는 근골격계 수술을 앞두고 있는 환자를 대상으로 라벤더를 이용한 향기흡입이 수술전 불안 감소에 미치는 효과를 규명하기 위해 시행되었다. 연구설계는 비동등성 대조군 전-후 설계의 유사실험연구(Quasi-experimental design)이다. 연구의 대상은 척추마취나 부분마취로 근골격계 수술을 받는 대상자 60명으로 실험군 30명 대조군 30명이었다. 연구도구는 활력징후 중 혈압과 맥박, 수술 전 불안 자가평가 도구 APAIS(Amsterdam preoperative anxiety information scale)이다. 자료분석은 PASW(SPSS)20.0을 이용하여 실험군과 대조군간의 동질성 검증을 t-test, $x^2$검증, Fisher's exact test, paird t-test를 이용하여 분석하였다. 연구결과에서 라벤더 향기흡입이 근골격계 수술환자의 수술전 불안을 감소시키고, 향기요법 시행 후에 수축기 혈압과 이완기 혈압의 유의미한 감소를 보이는 결과를 나타냈다. 이러한 결과는 수술을 앞둔 환자에게 비약물적 중재를 통해 불안의 감소 및 혈압과 맥박을 안정화시키기 위한 간호전략으로 향기요법을 사용할 수 있을 것이라 사료된다.

• 성인간호학회지
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• 제16권1호
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• pp.135-145
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• 2004

Purpose: The purpose of this study was to examine the effects of aroma oil inhalation using peppermint and bergamot on nausea vomiting and anorexia in cancer patients receiving chemotherapy. Method: Study subjects were 30 patients who had experienced nausea and vomiting when they had been hospitalized in K university hospital located in D city after receiving more than two Cisplatin combination chemotherapy treatments. Among them 15 patients were in the experimental group doing aroma oil inhalation and the other 15 patients were in the control group without aroma oil inhalation. The data were collected from February 1, 2002 to May 17, 2002. The data were analyzed with SPSS WIN 10.0 program using frequency, percentage, $x^2$-test, t-test, Repeated Measures ANOVA. Result: 1) The degree of nausea and vomiting in the experimental group with aroma oil inhalation using peppermint and bergamot were significantly lower than that of the control group. 2) The degree of anorexia in the experimental group with aroma oil inhalation using peppermint and bergamot were significantly lower than that of the control group. Conclusion: aroma oil inhalation was effective for relieving patients' nausea vomiting and anorexia receiving chemotherapy. Therefore, it is proposed that aroma oil inhalation should be applied as a supportive nursing arbitration method to relieve patients' nausea vomiting and anorexia who are receiving chemotherapy.

• 호스피스학술지
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• 제4권2호
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• pp.42-51
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• 2004

Purpose: The purpose of this study was to examine the effects of aroma oil inhalation using peppermint and bergamot on nauseaㆍvomiting and anorexia in cancer patients receiving chemotherapy. Method: Study subjects were 30 patients who had experienced nausea and vomiting when they had been hospitalized in K university hospital located in D city to receiving more than two Cisplatin combination chemotherapy. Among them 15 patients were in the experimental group doing aroma oil inhalation and the other 15 patients were in the control group without aroma oil inhalation. The data were collected from February 1, 2002 to May 17, 2002. The data were collected from February 1, 2000 to May 17, 2002. The data were analyzed with SPSS WIN 10.0 program using frequency, percentage, X2-test, t-test, Repeated Measures ANOVA. Result: 1)The degree of nauseaㆍvomiting on the experimental group with aroma oil inhalation using peppermint and bergamot were significantly lower than that of the control group. 2)The degree of anorexia on the experimental group with aroma oil inhalation using peppermint and bergamot were significantly lower than that of the control group. Conclusion: aroma oil inhalation was effective for relieving patients' nauseaㆍvomiting and anorexia receiving chemotherapy. Therefore, it is proposed that aroma oil inhalation should be applied as a supportive nursing arbitration method to relieve patients' nauseaㆍvomiting and anorexia who are receiving chemotherapy.

• 생명과학회지
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• 제26권3호
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• pp.346-352
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• 2016

전통적으로 향기(aroma) 치료법은 대체 의학 분야에서뿐만 아니라 정신과 치료에서도 실제로 널리 활용 되었다. 본 연구에서는 일차적으로 odorant-binding protein (OBP) 활성 부위에 대한 스마트 웨이브(SW) 주요 화학적 조성물과 OBP 활성 리간드인 citrate anion 결합 친화도를 비교 분석하였다. SW는 OBP 활성 부위에 대해 citrate anion보다 훨씬 높은 분자 결합 친화도를 나타내었다. 임상적으로 SW혼합 조성물을 후각으로 흡입한 전/후, 뇌파에 어떠한 변화가 유도되는지를 비교 분석하였다. 18명의 피험자들을 대상으로 SW 흡입 전/후 뇌파의 명상(안정감) 변화 지수를, 악취를 내는 음성 대조군(EV)과 파우더향을 발산하는 양성 대조군(HB) 흡입 전/후의 변화 값과 비교하였다. SW를 흡입한 실험군에서는 SW를 흡입하고 난 후 상쾌함을 경험하였다는 반응을 나타냈으며 SW흡입군에서는 EV흡입군과 HB흡입군에 비하여 뇌파의 명상 지수가 현저하게 안정된 값으로 유도되는 것을 확인하였다. 또한 EV흡입 이후 SW를 흡입하였을 때 뇌파 명상 지수가 안정 뇌파값 범위로 개선되었다. 결과적으로 SW혼합 조성물은 OBP에 효과적으로 결합하여 OBP를 활성화 시키고, SW 흡입은 뇌파를 효과적으로 통제하여 심리적 상태를 현저하게 안정화 시키는 것을 확인하였다. 본 연구를 통하여 SW흡입법은 외부의 스트레스 자극으로부터 뇌 활성을 효율적으로 조절할 수 있는 새로운 향기 치료법으로의 활용이 가능하다고 판단된다.

• 성인간호학회지
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• 제22권2호
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• pp.153-160
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• 2010

Purpose: The purpose of this study was to investigate the effects of aromatherapy on stress, fatigue, mood, and vital signs of the nurses in the operating rooms. Methods: The data were collected from September 2007 to February 2008 in the operating room at K hospital located in Seoul, Korea. A total of 48 nurses were recruited. Among them, 25 nurses were randomly assigned to an experimental group and 23 were assigned to a control group. Experimental group was provided with aroma inhalation by necklace which had essential oil mixture of 0.2 cc. For aroma inhalation, Lavender, Zeranium and Mazoram were mixed in ratio of 5:3:2. In order to test the effectiveness of aroma inhalation, the pretest and posttest results for stress, fatigue, mood, and vital signs were compared between the experimental group and the control group. The data were analyzed by unpaired t-test and ANCOVA using the SPSS/WIN 15.0 program. Results: There were statistically significant decreases in the stress and fatigue scores, and increase in the mood scores and showed significant relaxation in the vital signs after the aroma inhalation. Conclusion: The aromatherapy had the positive effects on stress, fatigue, mood, and vital signs.

• 성인간호학회지
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• 제17권3호
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• pp.358-367
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• 2005

Purpose: This study was to test some effects on pain, depression and ego integrity of the elderly by adapting group reminiscence therapy with mugwort fragrance to the elderly with chronic pain. Method: The research was executed from April 2001 through September 2001, and research participants were male and female olderly people randomly assigned from 3 environmentally similar day care centers. They were divided into experimental group A and B, and a control group; The control group was divided into a daily care group and a regularly visiting group, and the experimental group A was for group reminiscence therapy with mugwort fragrance inhalation and the group B for group reminiscence therapy. Result: The group reminiscence therapy with mugwort fragrance inhalation showed significant effects on decrease of pain and depression, and improvement of ego integrity, and for 2 weeks after the treatment proved its continuous effect. Conclusion: The result above explains the fact the mugwort fragrance stimulates reminiscence and shows curing effects. In further researches, it is necessary to adapt various health problems of the elderly, not only to the aged with chonic pain.

• 여성건강간호학회지
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• 제9권1호
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• pp.70-79
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• 2003

The purpose of this study was to investigate the effects of Aromatherapy, inhalhtion method using Clarysage essential oil on stress in middle-age women. The study design was a one-group pretest-posttest design. The subject were 44 middle-age women with stress in inhalation method of Clarysage essential oil was 2 drops of oil on tissue at 10, 14, 18, before bed for 2 weeks. The study was carried out from August 1 to September 20, 2002. The scale used in the study was the stress scale of Park, Sun Young(1999). The study data was analyzed by frepuency, percent age and t-test using SPSS Win 10.0 program. Result were as follows : 1. The score of physical stress scale was significantly decresed after use of inhalation of Clarysage essential oil. 2. The score of psychological stress scale was significantly decresed after use of inhalation of Clarysage essential oil. In conclusion, the results of this study suggest that inlalation method using Clarysage essential oil is positively supported in stress reduction in middle-aged women.