• Journal of Marine Bioscience and Biotechnology
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• v.7 no.2
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• pp.35-41
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• 2015

Whales are marine mammals that are fully adapted to aquatic environment. Whales breathe by lungs so they require adaptive system to low oxygen concentration (hypoxia) while deep and prolonged diving. However, the study for the molecular mechanism underlying cetacean adaptation to hypoxia has been limited. Hypoxia-inducible factor (HIF) is the central transcription factor that regulates hypoxia-related gene expression. Here we identified HIF-binding sites in whale genome by phylogenetic footprinting and analyzed HIF-target genes to understand how whales cope with hypoxia. By comparison with the HIF-target genes of terrestrial mammals, it was suggested that whales may retain unique adaptation mechanisms to hypoxia.

• Journal of Marine Bioscience and Biotechnology
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• v.4 no.1
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• pp.15-23
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• 2010

Seaweed has been consumed especially in the Asia since centuries ago as a vegetable (Matsukawa, 1997; Burtin, 2000; Raghavendran 2003). Seaweed has many valuable nutrients i.e. as a mineral resources, vitamin, and non-caloric fiber, also has potential antioxidant resources. Such of nutrition consists in the Seaweed is Chlorophyll, Carotene, Fucoxantine, Luteen and Zeaxantine, Polysaccharide and Diet Fiber, Mineral, Protein and Amino Acid, Fat and Fatty Acid, Vitamin, Polifenol, also Methanol. The benefits of some nutrition content on seaweed are as an antioxidant, slimmer agent, anti-diabetes, healthy for heart, eyes health, Iodium source, and some kind of vitamins functions. As a conclusion, developing research about seaweed we believe it would be a part of medicine material and food processing, also cosmetic industrial.

• Journal of Marine Bioscience and Biotechnology
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• v.4 no.1
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• pp.11-14
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• 2010

The genus Porphyra, consisting of 133 species includes several economically valuable species (i.e. P. yezoensis, P. tenera, P. pseudolinearis etc.). They are predominantly consumed and cultivated in East Asian countries such as Japan, Korea and China, and they are regarded as a big commercial market today. In addition to the industrial importance, P. yezoensis is currently regarded as a feasible candidate for a model plant in marine biotechnology, therefore there are a wide range of studies being undertaken: strain-preservation, development of mutant strains and genetic analysis and exhaustive molecular analysis including EST and macro/micro array. Focusing on the activities of our research group, current situation and future perspectives in marine biotechnological studies using P. yezoensis will be discussed in this mini review.

• Journal of Marine Bioscience and Biotechnology
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• v.4 no.1
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• pp.6-10
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• 2010

Indonesia is well-known as biggest producer of seaweed especially for Eucheuma and Gracilaria and also has huge potential resources and capability to develop seaweed cultivation and product. There are several provinces which have potential resources and have been contributing on seaweed production. The next challenge about seaweed production is using integrated system on brackishwater and marine aquaculture. Furthermore, about 2,000,000 ton of potential seaweed production is not explored yet. This article also tries to figure out some related aspects which are technical, economical and forecasting aspect. There is a disease which named "ice-ice" is one of the main problem and giving a new challenge in developing of problem solving for seaweed cultivation method. Economical parameters are also main important key to find out the feasibility of seaweed cultivation industry. In addition, the seaweed cultivation and production in Indonesia also have potential performance on biofuel resources as a part for solving the world problem on energy demand.

• Journal of Marine Bioscience and Biotechnology
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• v.4 no.1
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• pp.1-5
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• 2010

With the world's population increase, demands of fish production increased rapidly. Because of the demand increase, methods of aquaculture also become more intense. With the increasing intensity of aquaculture, more metabolites in the system are accumulated. The metabolites accumulated in the system turn to the causatives of water quality deterioration and become limiting factors for fish growth. Due to the toxicity of ammonia, ammonia removal is needed in aquaculture system. Biofilters, often referred as biological filter or nitrification filter are commonly used in recirculating aquaculture system to remove ammonia and convert it to nitrite, and then to nitrate.

• Journal of Marine Bioscience and Biotechnology
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• v.2 no.1
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• pp.11-22
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• 2007

This aims to review natural products transformed by mimic intestinal metabolisms with microorganisms and hydrolytic enzymes, which exhibit enforced biological activity, higher extraction yield and identification of active components. In the process, transformation to the smaller active compounds with enzymes and microbes mimics the pharmacological action of natural products by intestinal bacteria. In order to establish conditions for the fermentation and enzyme reaction, it is required to choose several natural products for biotransformation and investigate the optimal conditions for the fermentation or the enzyme reaction such as composition, temperature, pH, inoculum, and cultivation time. It is expected an increase of the internal absorption of the active materials without regard to the intestinal microbes or its ability through biosynthesis of the active materials by the microbes and enzymes. And this techniques can be applied to biotransformation of natural products such as sesaminol, resveratrol, 1-deoxy nojirimycin, naringenin, quercetin, and baicalin and to the metabolism study using the animal model.

• Journal of Marine Bioscience and Biotechnology
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• v.2 no.1
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• pp.23-33
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• 2007

The constraints of traditional fish drying in Bangladesh have been reviewed and an effective solar fish dryer was developed with the small-scale processors and fishermen using locally available cheaper materials in order to dry fish in coastal region. After successful field testing, new solar dryer was demonstrated within the community in 3 different locations of Cox's Bazar for several batches of operations in each location from late September to March and found very effective in terms of architectural suitability, operational feasibility, technical efficiency, out-put quality (good texture, colour, flavour and long storage time), user's acceptability, commercial viability and environmental adequacy. A simple cost-profit analysis was done with the community operated products, which indicates that the new solar fish dryers could be operated profitably in coastal regions where sun-light and air flows are abundant.

• Journal of Marine Bioscience and Biotechnology
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• v.2 no.1
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• pp.55-59
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• 2007

The oil and concentrated protein powder from squid viscera was extracted and recovered by a semi-batch supercritical carbon dioxide ($SCO_2$) extraction system and the degree of oxidation in the extracted oil was measured in order to compare with extracted oils using organic solvents. The degree of storage in treated squid viscera by $SCO_2$ extraction was measured in order to compare with untreated squid viscera. As results obtained, it was found that the auto-oxidation of the oils using $SCO_2$ extraction occurred very slowly compared to the oils by organic solvent extraction. And the treated squid viscera by $SCO_2$ extraction was reached the point of initial rottenness slowly than untreated squid viscera.

• Journal of Marine Bioscience and Biotechnology
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• v.9 no.2
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• pp.58-64
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• 2017

Polysaccharides are useful materials for keep skin moisturizing and skin improvement cosmetic materials. We have isolated polysaccharides form Gracilariopsis sp. The polysaccharide derived from Gracilariopsis sp. have various size of 300kDa, 500kDa and over 1,000kDa. The volunteers applied a cream formula with polysaccharides from Graciariopsis sp. for 4 weeks. We found significant improvement of wrinkles and skin texture. We also found an effect of improving skin elasticity. When the moisture reduction rate of the skin was 2.8% lower than the 5.1% of hyaluronic acid. The polysaccharide extract from Gracilariopsis sp. showed stable pH and viscosity. The polysaccharides derived from Gracilariopsis sp. could be used as a cosmetic material.

• Journal of Marine Bioscience and Biotechnology
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• v.9 no.2
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• pp.30-34
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• 2017

Microorganisms are contained filtered sea water that is why we often observed co-existing copepod species in the large-scale rotifer culture tanks. In this study, we investigated about taxonomical study of co-existing copepods in Brachionus rotifer mass culture tanks of several seafarming centers at Jeju-do and Pusan, Korea by microscope. Also, we counted number of copeods and density in 10 mL of cultured sea water and distinguished growing patterns and sex. As results, we can identified 4 species copepods, 2 species of Tisbe, 1 species of Tigriopus and 1 species of Apocyclops.