• The Monthly Diabetes
• /
• s.289
• /
• pp.13-18
• /
• 2013

당뇨병성 족부질환은 당뇨병과 그 합병증의 결과로 발생하는 발의 손상으로 정의할 수 있으며, 혈당 조절이 잘되지 않는 당뇨병 환자에서 신경 및 혈관 합병증의 결과로 발생하게 되어 입원치료, 발절단 치료를 통한 장애 발생, 그리고 조기 사망으로 이어지는 의료, 사회, 경제적인 다 방면에서 부담을 주는 질환이다. 당뇨병성 족부질환은 역사적으로 당뇨병의 치료 역사뿐만 아니라 항생제 사용 역사와도 깊은 관련이 되어 있으며, 특히 최근에는 당뇨병의 자가관리교육이 보편화 되면서 스스로 당뇨병 합병증을 관리하는 방법과 정보를 제공해 주는 당뇨병 관리 교육과도 밀접한 관계가 있을 것으로 여겨진다.

• Journal of the korean veterinary medical association
• /
• v.37 no.2
• /
• pp.168-176
• /
• 2001

Staphylococcus aureus의 박멸은 모든 낙농목장에서 실제적 목표가 되지는 못 한다. 그러나 경영수준에서 발생의 감소는 기타 전통적 전염성 유방염관리계획을 관심 있게 사용 할 때, 예방주사와 항생제치료계획을 통하여 성취 될 수 있을 것이다. 그리고 만일 첫 분만 우에서 시작한다면은 더욱 성공적으로 나타날 것이다. Sta. aureus유방염에 대한 예방주사치료작전은 낙농 인이 목장SCC를 낮추는 운동으로 더욱 중요하게 성취될 수 있을 것이다. 그리고 앞으로 유질표준에 도달된다.

• The Journal of the Korean dental association
• /
• v.36 no.3 s.346
• /
• pp.199-202
• /
• 1998

1940년대부터 1970년대까지 치주치료의 목적은 복잡핞 치주외과적 수술을 통하여 치주낭을 제거 또는 감소시키는 것이었다. 그러나 1960년대와 1970년대에 이루어진 연구 결과를 보면 치주질환의 병인발생에 있어서 치태의 역할과 적절한 구강위생의 중요성이 강조되었다. 즉 치태를 제거하기 위해서 치솔과 치약, 그리고 보조기구를 이용한 구강위생방법(기계적인 처치)과 전신적 및 국소적 항생제투여, 그리고 양치용액의 사용(화학적인 처치)과 같은 비외과적 처치방법이 관심의 대상이 되었다. 여기에서는 치태를 효과적으로 관리하기 위한 기계적인 치료방법과 화학적인 치료방법에 대해 살펴보고자 한다.

• KOREAN POULTRY JOURNAL
• /
• v.33 no.7 s.381
• /
• pp.84-87
• /
• 2001

우리나라에서는 어린이 설사, 위염을 치료하고 충치를 예방할 수 있는 달걀이 지난해말 개발되어 시중에 시판되고 있다. 이러한 기능성 계란은 한국식품개발연구원과 에그바이오텍, 시트리 등 바이오 업체 중심으로 개발되어 다한영농법인, 강남농장, 에그원, 가농바이오 등 농장에서 생산하여 소비자에게 공급하고 있다. 그러나 이러한 기능성계란은 인체용으로 사용되어 왔고 가축 질병 치료제로 사용되지는 못했다. ㈜단$\cdot$바이오텍(대표 김정우)은 첨단 생물공학기술을 이용하여 동물생체에 친화적인 고품질의 신생물질(면역항체, lgY)의 생산을 산업화함으로써 동물과 사람의 치료시 화학제제 및 항생제의 장기복용 및 오$\cdot$남용으로 인해 발생되는 제반 문제점을 해결한다는 사명감을 가지고 지난해 10월 출범하여 업계의 관심이 집중되고 있다.

• Journal of the korean academy of Pediatric Dentistry
• /
• v.39 no.1
• /
• pp.43-50
• /
• 2012

The concept of revascularization of necrotic pulps regained interest and became an alternative conservative treatment option for young permanent teeth with immature roots. Revascularization of immature teeth with apical periodontitis depends mainly on disinfection of the canal. Since the infection of the root canal system is considered to be polymicrobial, a combination of drugs would be needed to treat the diverse flora. A triple antibiotic mixture of metronidazole, ciprofloxacin, and minocycline was used as an intracanal medicament. However, discoloration was developed after applying the triple antibiotic mixture. It is believed that the marked discoloration is related to the use of minocycline. The aim of this article was to present cases of coronal discoloration after triple antibiotic therapy in immature tooth and was treated with bleaching technique to control coronal discoloration. In conclusion, revascularization by using triple antibiotics promotes a paradigm shift in treating endodontically involved permanent teeth. However, we should understand that triple antibiotics containing minocycline induces tooth discoloration. Further research to prevent coronal discoloration should be investigated and suggested for the safe use of triple antibiotics.

• Tuberculosis and Respiratory Diseases
• /
• v.64 no.4
• /
• pp.293-297
• /
• 2008

Mycobacterium fortuitum usually causes colonization or transient infection in patients with underlying lung disease, such as prior tuberculosis or bronchiectasis. The majority of these patients may not need to receive antibiotic therapy for M. fortuitum isolates. We report here on a patient with M. fortuitum lung disease and who was successfully treated with combination oral antibiotic therapy. A 53-year-old woman was referred to our institution because of purulent sputum and dyspnea. A chest radiograph and computed tomography scan revealed cavitary consolidation in the left upper lobe and multiple small cavities in the left lower lobe. Numerous acid-fast bacilli (AFB) were seen in multiple sputum specimens and M. fortuitum was identified by culture from the sputum specimens. The patient received antibiotic treatment including clarithromycin, ciprofloxacin and sulfamethoxazole, because her symptoms were worsening despite conservative treatment. Sputum conversion was achieved after one month of antibiotic therapy. Both the patient's symptoms and radiographic findings improved after 10 months of antibiotic therapy.

• Journal of the korean academy of Pediatric Dentistry
• /
• v.44 no.1
• /
• pp.47-55
• /
• 2017

This study evaluated critical factors influencing the success of regenerative endodontic treatment for necrotic immature permanent teeth. The study enrolled patients who had regenerative endodontic treatment in a necrotic immature permanent tooth through 1-year follow-up. Possible explanatory variables related to the success rates for 46 teeth were age, gender, dental stage at the initial appointment, etiology, treatment information, and clinical and radiographic outcomes. The dental stage at the time of regenerative endodontic treatment did not influence the success rate. The success rate was significantly related to the etiology of the necrotic immature tooth. The success rate according to etiology decreased in the following order: dens evaginatus, caries, and trauma. There was also a significant difference according to the type of antimicrobial. The success rate was influenced by appropriate disinfection of the root canal system, provision of a scaffold, and coronal sealing. Above all, careful case selection is necessary for treating a necrotic immature permanent tooth, especially in cases of trauma.

• Journal of Dental Rehabilitation and Applied Science
• /
• v.37 no.4
• /
• pp.294-300
• /
• 2021

Necrotizing periodontal disease caused by plaque bacteria is showed clinical findings including pseudo-membrane, interproximal necrosis of the affected area, pain on palpation and gingiva bleeding. Microbiological examination is showed that patients have fusospirochetal bacteria. Two patients who were provisionally diagnosed as necrotizing periodontal disease received nonsurgical periodontal treatments in conjunction with dressing using 3% hydrogen peroxide and local antibiotic delivery. Before and 3 - 5 days after initial treatment, the levels of periodontal bacteria in gingival crevicular fluid obtained using quantitative PCR were compared. After treatment, patients recovered normal gingiva. The number of periodontal diseases related bacterial species decreased from seven or eight to one. As a result, periodontium of patients with necrotizing periodontal disease was recovered to normal periodontium by nonsurgical periodontal treatments.

• Journal of Chest Surgery
• /
• v.34 no.3
• /
• pp.252-255
• /
• 2001

본 30세 여환은 류마치스성 심장판막질환 진단하네 승모판막 및 대동맥판막 치환술 시행후 종격동염 발생하여 지속적 종격동 세척 및 3주간의 항생제 치료후 퇴원하였다. 외래 추적중 다시 감염 및 염증소견 보여 입원하여 혈액배양검사와 흉부전산화 단층촬영시행하였다. 검사상 종격동염의 이후 3주간의 항생제 치료에도 염증 소견이 지속되어 다시 시행한 흉부 전산화단층촬영상 상행대동맥에 거대 가성대동맥류소견보여 재개흉술을 시행하여 초저체온 완전 순환정지 하에 가성대동맥류를 절제한 후, 우심낭편을 이용하여 대동맥 성형술을 시행하였다. 수술후 환자는 순조롭게 회복하였으며 현재 외래에서 추적관리하고 있다.

• Investigative Magnetic Resonance Imaging
• /
• v.7 no.1
• /
• pp.31-38
• /
• 2003

Purpose : To analyze the serial changes of proton magnetic resonance (MR) spectra in the abscess and to determine the effect of the antibiotic treatment on the metabolite patterns. Materials and Methods : MR imaging and MR spectroscopy of an experimentally induced abscess were performed sequentially for four weeks at interval of one week in both the control group (n=5) and the antibiotic treatment group (n=5). On MR imaging, the shape and the size of the abscess were analyzed. On MR spectroscopy, the resonance peaks of metabolites were assigned on the basis of reported peaks in the literature. The metabolite ratios measured by using N-acetyl alanine as an external reference and by using lipid as an internal reference were compared in both the control and treatment g roups. Results : The abscesses were seen as cystic masses on MR imaging. On MR spectroscopy, the variable peaks of acetate, succinate and various amino acids, which are the metabolites of infection, were identified in the control and antibiotic treatment groups. The most frequent peak was that of acetate at 1.92ppm (70%). Both the peak ratios of acetate to lipid and acetate to external reference tended to decrease in the treatment group while the ratios did not change significantly in the control group. Conclusion : MR spectroscopy is useful not only for the diagnosis of abscess but also for monitoring the evolution of the abscess by using the acetate peak.