• Tuberculosis and Respiratory Diseases
• /
• v.51 no.4
• /
• pp.325-333
• /
• 2001

Background : This study aimed to estimate the clinical outcome and identify the characteristics of a group of patients with pulmonary tuberculosis who completed anti-tuberculosis therapy with the First-line drugs in spite of having positive smear results with negative sputum culture results over the previous six months. Method : A retrospective chart review of 21 patients who fulfilled the above criteria between 1995 and 1999 was performed. The laboratory data as well as the clinical data of the patients with positive smear results and negative culture results over a six months period were reviewed. Results : The negative conversion of sputum culture results was achieved within $1.3{\pm}1.2$ months and the negative conversion of the sputum smear results was accomplished during $9.5{\pm}3.3$ months. Chest X-rays at 5 months following the institution of anti-tuberculosis therapy from all patients revealed improvements. Four out of 21 patients(19%) relapsed during the follow up, $15.2{\pm}13.4$ months after administering anti-tuberculosis therapy for $13.3{\pm}3.1$ months. Relapses were confirmed from between 3 months and 4 months after the treatment completion. Only one of the four relapses had no past history of anti-tuberculosis therapy and the others had prior treatment twice (p<0.01). The period of anti-tuberculosis treatment was extended to a mean of $4.6{\pm}2.6$ months in 12 patients. However, prolongation of anti-tuberculosis therapy had no affect on the relapse rate (odds ratio, 95% CI 0.18, 2.15). Conclusion : Prolongation of therapy with the First-line drugs is not necessary for patients with persistently positive smear results over 6 months and negative culture results. A patient who has had prior anti-tuberculosis therapy more than twice should be paid the closest attention.

• Journal of agricultural medicine and community health
• /
• v.43 no.2
• /
• pp.108-113
• /
• 2018

목적 글루포시네이트암모늄은 비선택성 제초제로 1984년 일본에서 개발되었으며, 급성 중독시에는 위장관계 증상뿐만 아니라 의식변화, 경련, 호흡부전 및 기억소실 등과 같은 다양한 임상증상을 보이는 것으로 알려져 있다. 한국에는 1994년 소개된 이후로 널리 사용되고 있으며, 사용량의 증가와함께 음독환자가 점점 증가하여 사회적 문제가 되고 있다. 저자들은 최근 글로포시네이트 중독 환자에서 초기치료 후 지연성 악화를 보였던 2례를 문헌고찰과 함께 보고하고자 한다. 방법 및 결과 첫 번째 증례는 62세의 남자환자로 음주상태에서 글루포시네이트암모늄 음독 후 의식 저하 상태로 발견되어 응급실로 이송되었다. 응급 위세척을 시행 후 보존적 치료 및 집중모니터링을 유지하였고, 의식수준은 6시간 후에 거의 명료한 상태로 호전되었다. 지연성 악화의 가능성에 대해설명하고 지속적인 경과관찰 및 치료를 위해 집중치료실 입원이 필요함에 대해 설명하였으나, 환자와 보호자는 타상급병원으로의 전원을 원하였다. 환자는 이송 중에 발생한 심폐정지로 심폐소생술을 시행하였으나, 회복되지 못하고 사망하였다. 두 번째 증례는 54세의 남자 환자로 글루포시네이트암모늄 음독 후 발생한 의식 변화로 응급실로 이송되었다. 내원시 의식은 혼미한 상태였으며 앞의 증례와 같이 응급 위세척을 시행하였다. 본 환자는 초기치료 후 본원 집중치료실에서 지속적인 혈액 및 생화학적 검사를 시행하였으며, 집중모니터링 및 치료를 유지하였다. 입원 2일째 혈액검사 소견은 호전 중이었으나, 경련이 발생하였으며 의식은 혼미한 상태가 지속되었다. 신경과 협진하여 뇌파검사를 시행 후 항경련제를 증량한 후로 경련은 발생하지 않았다. 입원 7일째에는 의식 수준은 거의 명료한 상태까지 호전되었다. 입원 13일째 혈액 및 생화학검사에서 약간의 혈색소 감소 외에는 정상소견을 보였으며, 뚜렷한 신경학적 합병증 없이 퇴원하였다. 결론 급성 글루포시네이트중독 환자는 매우 다양한 임상증상을 보이며 초기치료 후에 상태가 안정적이더라도 지연성으로 임상적 또는 신경학적 악화가 발생할 가능성이 있으므로 치료에 유의하여야 한다.

• Journal of the Society of Cosmetic Scientists of Korea
• /
• v.45 no.3
• /
• pp.307-317
• /
• 2019

To develop sustainable new natural anti-aging ingredients from Korean native plants, we investigated the cultivation potential of Nymphoides indica using the eco-friendly aquaponics system, and tested the anti-aging effects from N. indica extracts. N. indica could be grown in aquaponics system using floating leaved deep water culture method, and propagated through rhizome propagation. It was confirmed that the nitrate ($80{\mu}g/mL$), potassium ($63.5{\mu}g/mL$) and water temperature ($25^{\circ}C$) greatly affected the cultivation of the N. indica. In addition, synergistic effects were found when two major components (3,7-di-O-methylquercetin-4'-O-${\beta}$-glucoside & sweroside) were present at more than about $5{\mu}g/mL$. The extract had a significant effect on the recovery of skin cells damaged by environmental pollutant such as $benzo[{\alpha}]pyrene$, ammonium nitrate, formaldehyde. It also suppressed $PGE_2$, $TNF-{\alpha}$ and COX-2, and inhibited the production of MMP-1. Taken together, the results suggested that the standardized extracts of N. indica cultivated in the aquaponics has considerable potential as a new cosmetics ingredient with an anti-aging effect.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
• /
• 2023.05a
• /
• pp.146-147
• /
• 2023

해양사고는 도로교통과 달리 지속적으로 증가하고 있으며, 인명피해가 주로 발생하는 주요 사고의 치사율은 도로교통의 11.7배 이상이다. 해양사고는 외부 환경에 따라 사고 위치가 변하고 즉각적인 조치가 어려워 타 교통에 비해 대형 사고로 이어질 가능성이 매우 크다. 그러나 여전히 사고가 발생하고 난 후 대응하는 등 사후적 관리 단계에 무르고 있어 사고의 주요 요인을 사전에 식별·관리하는 선제적 관리단계로의 전환 필요성이 대두되고 있다. 따라서 본 연구에서는 해양사고 발생 지점 밀도 기반의 가변 공간 군집체계를 반영한 해양사고 예측모델을 개발하였다. 반복적인 공간 가산분석을 통해 밀도가 높을수록 작은 규모의 격자 체계를 가질 수 있도록 상세한 공간 군집체계를 구성하였으며, 단순 사고 위험도 예측뿐만 아닌 사고 인과관계를 설명할 수 있는 BN(Bayesian Network) 기반의 모형을 사용하여 해양사고 위험예측 모델을 개발하였다. 또한, Cost-of-Omission을 통해 해양사고 예측확률의 변화와 각 변수들의 영향력을 확인하였으며, 월별 해양사고예측 결과를 GIS를 활용하여 2D/3D 기반으로 시각화하였다.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
• /
• 2023.11a
• /
• pp.95-97
• /
• 2023

자율운항선박(MASS)의 원격제어기술은 원격지에서 MASS를 원격제어자에 의해서 제어하기 위한 기술이다. 2023년도 현재 원격제어시스템의 통합구성이 완료되었고, 하반기부터는 해상실험을 통한 시스템 검증작업을 진행할 예정이다. 이러한 시스템 검증 이후에는 원격제어 시 발생할 수 있는 다양한 문제에 적극 대응할 수 있는 위기관리 기술의 개발이 필요하다. 현재 식별된 위기는 통신 두절에 따른 제어 불능, 간헐적 통신 불능에 따른 데이터 손실, 대용량 데이터 전송에 따른 제어명령과 제어응답 사이의 지연에 의한 선박조종의 어려움, 원격제어자의 인적오류에 의한 예상하지 못한 해양사고발생 가능성 등이다. 본 연구의 목적은 4가지 주요 요소(선박, 통신, 제어시스템, 원격 제어자)로 구성된 원격제어 시스템에서 발생 가능한 다양한 위기를 적극 억제할 수 있는 기법개발을 고찰하여 향후 원격제어기술 연구에 적용하기 위한 것이다. 특히, 통신 두절로 인한 암흑시간(blind time) 동안 원격제어 불능을 해결할 수 있는 위기대응 방법, 과도한 데이터 전송지연에 따른 위험수준 평가와 가시화 방법 등을 논의한다. 본 연구는 자율운항선박의 원격제어를 안전하게 지속가능한 상태에서 운영할 수 있는 기법의 적용할 수 있을 것으로 기대된다.

• Journal of Korea Port Economic Association
• /
• v.35 no.1
• /
• pp.139-162
• /
• 2019

In the case of Korea, policy support for shipping companies is limited, and the financial support should address the scale and period of support. Comprehensive measures are needed to boost the chances of reviving the industry. In order to secure competitiveness, the shipping companies need to make continuous efforts, prepare for the future by strengthening environmental regulations, and ensure that they have the ability to be flexible in their responses. The shipbuilding industry witnessed some improvement last year amid severe recession, but reforms are needed to address external and internal structural problems; further, to gain the characteristics of future leading industries, it is necessary to secure core technologies, as well as differentiated and specialized industrial competitiveness among rival countries through joint government intervention and joint R&D investment. Taking these steps will ensure that it has environment-friendly vessels and economic shipbuilding capabilities. The competitiveness of Busan Port should enable the utilization of the geopolitical characteristics of East Asia and contribute to: regional economic revitalization; development of its status as hub port; and securing the position of developed countries in East Asian logistics. For this purpose, it is necessary to establish a strategy to: expand the usability of shipowners/carriers; improve the quality of port operations; improve the portability of the smart system; expand the port of mega-ocean carriers; speed up port operations; and create low-cost ports. The establishment of a network of four countries will also require long-term global linkages. For example, there is a need to establish a logistics network between Eurasia and the European region, which will use the Russian Land Bridge System, as well as that of China.

• Korean Journal of Remote Sensing
• /
• v.38 no.6_1
• /
• pp.1463-1478
• /
• 2022

Maritime transport accounts for 99.7% of the exports and imports of the Republic of Korea; therefore, developing a vessel monitoring system for efficient operation is of significant interest. Several studies have focused on tracking and monitoring vessel movements based on automatic identification system (AIS) data; however, ships without AIS have limited monitoring and tracking ability. High-resolution optical satellite images can provide the missing layer of information in AIS-based monitoring systems because they can identify non-AIS vessels and small ships over a wide range. Therefore, it is necessary to investigate vessel monitoring and small vessel classification systems using high-resolution optical satellite images. This study examined the possibility of developing ship monitoring systems using Compact Advanced Satellite 500-1 (CAS500-1) satellite images by first training a deep learning model using satellite image data and then performing detection in other images. To determine the effectiveness of the proposed method, the learning data was acquired from ships in the Yellow Sea and its major ports, and the detection model was established using the You Only Look Once (YOLO) algorithm. The ship detection performance was evaluated for a domestic and an international port. The results obtained using the detection model in ships in the anchorage and berth areas were compared with the ship classification information obtained using AIS, and an accuracy of 85.5% and 70% was achieved using domestic and international classification models, respectively. The results indicate that high-resolution satellite images can be used in mooring ships for vessel monitoring. The developed approach can potentially be used in vessel tracking and monitoring systems at major ports around the world if the accuracy of the detection model is improved through continuous learning data construction.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
• /
• 2011.06a
• /
• pp.376-378
• /
• 2011

Hamburg is going with the HafenCity Project to create new urban space for city's bustling central district. HafenCity will add an additional 155 hectares to Hamburg's central urban area, increasing its total area by some 40 percent. The new developments in HafenCity will be oriented towards the River Elbe and the great seaport. Its centre will have a close relation to water. They will be used for the construction of a fascinating mix of residential accommodation, offices, cultural and leisure amenities, retail facilities and restaurants set in a framework of an elaborate urban layout. This study is focusing on the purpose of the project goals, the task of the Hamburg authorities and GHS (Gesells chaft f$\ddot{u}$r Hafen und Standortentwicklung) and an urban planning ideas competition (draft masterplan). Regarding of the new trend of the reurbanisation in Europe, the aim of this study will be to find out, in which way Hafencity is trying to develope the new city district as a model for the European inner city of the 21st century.

• Journal of the Korea Concrete Institute
• /
• v.27 no.1
• /
• pp.75-83
• /
• 2015

This study discusses the long-term antifungal effect and antifungal performance of Hwangtoh mortars with various natural antifungal substances on five types of mold: Chaetomium globosum, Aspergillus niger, Aureobasidium pullulans, Gliocladium virens, and Penicillium pinophilum, which can be easily detected in the indoors and outdoors of buildings in damp environments. The antifungal performances of various natural antifungal substances extracted from Marjoram, Phytoncide, Thyme, Ginkgo leaves, and Chitosan (oligosaccharide) were investigated on the five types of mold, as a basic experiment. Using the natural antifungal substances selected for the basic experiment, antifungal mortars were made, and their antifungal performance and long-term antifungal effects were also investigated. The results clearly showed that the marjoram extract and their associated mortars had excellent antifungal performance. Also, their long-term antifungal effects were outstanding and at an equivalent level to those of the mortars with organic chemical antifungal agents. The optimum addition rate of the marjoram extract in the mortar was 5% by mass of binder. It was also shown that the phytoncide extract in the mortar needed an addition rate of more than 10% according to the mass of binder, considering the long-term antifungal effect and the antifungal performance.

• Journal of Korea Port Economic Association
• /
• v.26 no.2
• /
• pp.1-18
• /
• 2010

With the maturity and fierce competition of domestic logistics market, Korea government is actively working on the overseas investments in global logistics market after establishing the basic plan since 2006. In particular, India is selected one of promising countries for logistics investments since it has more 1.1 billion people and is regarded as post-China. In fact, a number of global logistics enterprises have started their businesses in the logistics market of India so that the competition already started. In this regard, it is highly necessary to find out feasible investment projects and then detemin the priority of the alternatives for successful investments. Therefore this study proposes a fuzzy-based AHP model by which the overseas investment problem was systematically structured and then evaluated. The model was established by exploiting a fuzzy theory and AHP for capturing the inexactness and vagueness of information. The results show that the investment of port operations is the number one priority in the India's logistics market and ODCY operations, road transportations, forwarding operations, inland depot operations in order. Finally the proposed model will help Korea's policy makers to have a better reliable investment strategy.