• Title/Summary/Keyword: 합성류

Search Result 662, Processing Time 0.037 seconds

ACE 억제제 합성 및 억제효과측정

  • 김병현;류은정
    • Proceedings of the Korean Society of Applied Pharmacology
    • /
    • 1994.04a
    • /
    • pp.219-219
    • /
    • 1994
  • 고혈압 치료제의 하나로 사용되고 있는 Angiotensin Converting Enzymc (ACE) 억제제를 본 실험실에서 개발한 $\alpha$-hydroxy ketomethylene isostere를 핵심요소로 하여 합성하였다. 합성한 억제제 후보물질의 억제효과는 Rabbit Ling으로 부터 단리된 ACE를 사용하여 분광학적인 방법에 의해 결정되었다. 화합물 1은 우수한 억제효과를 나타내었다.

  • PDF

Surface Property Evaluation of Geosynthetics by Rotational Abrasion Test (회전마모시험에 의한 토목합성재료의 표면특성 평가)

  • 전한용;류중재;진용범;류원석
    • Proceedings of the Korean Fiber Society Conference
    • /
    • 2003.10b
    • /
    • pp.303-304
    • /
    • 2003
  • 토목합성재료 중 부직포 및 직포 지오텍스타일이 지반구조물에 적응될 경우 구속하중 부가 시 흙과의 마찰로 인한 마모에 의해 지오텍스타일의 표면손상이 발생하게 되면 강도저하가 발생하여 구조물의 안정성에 중요한 영향을 미치게 된다. 일반적으로 지오텍스타일과 흙과의 마찰특성평가는 직접전단시험이나 인발시험에 의해 평가되지만, 이들 시험 모두 구속하중에 의한 전단 및 인발변형을 해석할 뿐이며, 마모에 의한 지오텍스타일 표면 손상이나 변화는 거의 고려되지 않는 실정이다. (중략)

  • PDF

Development of a Multichannel Eddy Current Testing Instrument(I) (다중채널 와전류탐상검사 장치 개발(I))

  • Lee, Hee-Jong;Nam, Min-Woo;Cho, Chan-Hee;Yoon, Byung-Sik;Cho, Hyun-Joon
    • Journal of the Korean Society for Nondestructive Testing
    • /
    • v.30 no.2
    • /
    • pp.155-161
    • /
    • 2010
  • Recently, the electromagnetic techniques of the eddy current testing(ECT), alternating current field testing, magnetic flux leakage testing and remote field testing have been used as a nondestructive evaluation method based on the electromagnetic induction. The eddy current testing is now widely accepted as a NDE method for the heat exchanger tube in the electric power industry, chemical, shipbuilding, and military. The ECT system mainly consists of the synthesizer module, analog module, analog-to-digital converter, power supplier, and data acquisition and analysis program. In this study, the synthesizer module and the analog module which are essential to the ECT system were primarily developed. The developed ECT system is basically a multifrequency type which is able to inject the maximum four frequencies based on the frequency and time domain multiplexing method. Conclusively, we confirmed that the EC signal was processed appropriately in each circuit modules, and the Lissajous EC signal was displayed in the impedance plane.

Synthesis and Tautomerism of Novel Quinoxalines (Part I) (새로운 Quinoxaline류의 합성과 토토머화 현상 (제1보))

  • Ho Sik Kim;Jin Hee Kim
    • Journal of the Korean Chemical Society
    • /
    • v.47 no.3
    • /
    • pp.241-249
    • /
    • 2003
  • The reaction of 3-(1-ethoxycarbonyl)ethyl-1,2-dihydro-2-oxoquinoxaline (8) with hydrazine hydrate gave 3-(1-hydrazinocarbonyl)ethyl-2-hydroxyquinoxaline (9). The reaction of compound 9 with substituted benzaldehydes and heteroaryl aldehydes afforded 2-hydroxyquinoxalines (10-12), respectively. The reaction of compound 9 with alkyl (ethoxymethylene)cyanoacetates and ethoxymethylenemalononitrile resulted in the intramolecular cyclization to give the 5-amino-1-[2-(3-hydroxyquinoxalin-2-yl)propanoyl]-pyrazoles (13), respectively. Compounds 10-13 showed the tautomerism between the lactam and lactim forms in dimethyl sulfoxide solution. The tautomer ratios were determined by the $^1H$ NMR. The herbicidal and fungicidal activities of the synthesized compounds were investigated.

Bottom Friction of Combined Wave-Current Flow (천해파와 해류의 해저면 마찰력)

  • 유동훈;김인호
    • Journal of Korean Society of Coastal and Ocean Engineers
    • /
    • v.13 no.2
    • /
    • pp.177-188
    • /
    • 2001
  • The paper presents the method to estimate the bottom shear stress driven by waves and current on rough turbulent flow. Parameter adjusting technique is suggested for the computation of bed shear stress driven by uni-directional flow, and the value ofpararneter is determined by comparing the computational results against Bijker's laboratory data. For the computation of combined flow bottom shear stress, two methods are presented; one is the modified Bijker approach (BYO Model) and the other is the modified Fredsoe approach (FY Model), both of which are refined by the present writers. BYO model is again refined in the computation of maximum shear stress, and the final version is tested against Bijkcr's laboratory data.

  • PDF

수열합성법에 기초한 질소가 도핑된 TiO2의 합성 및 특성연구

  • Jeong, Gyeong-Mun;Gwon, Gi-Yeong
    • Proceedings of the Korean Vacuum Society Conference
    • /
    • 2013.02a
    • /
    • pp.284-284
    • /
    • 2013
  • 최근연구에 의하면 가시광선에 활성을 띄는 TiO2 개발은 중요한 연구 과제이다. 우리는 몇 가지 아민류를 이용해 수열합성법으로 TiO2에 질소를 도핑 함으로써 그 가시광선 활성을 연구하였다. 그 특성연구로서 XRD, SEM, TEM을 통해 구조와 morphology을 나타내었으며, EDX와 XPS를 통해 질소도핑 유무를 밝혔다. UV-Visible 분광기를 통해서 시료 각각의 가시광선영역에서의 흡수 유무를 확인 하였으며, 마지막으로 가시광선 영역에서 광촉매 활성을 알아보기 위해서, 광원으로 Xe-lamp를 이용, methylene blue를 분해해 그 농도를 분석하여 가시광활성을 비교 분석하였다.

  • PDF

Current Status of Collection and Recycling of Used Plastics (폐플라스틱의 수거 및 재활용 현황)

  • 나근배
    • Resources Recycling
    • /
    • v.6 no.2
    • /
    • pp.47-59
    • /
    • 1997
  • Thc paper points oul ever increasing amounts of plastics used in dex, clopmg countries and the prohlelns associated with such increase. Tl~e current status of the production and usc of plaslic materials is reviewed. Also reviewed lncludc thc pahcicies and gu~dclmcs canccrning the treatment of used plastics which have already bccn mstitutcd.

  • PDF

Synthesis of 2-(Pyrazol-1-yl)quinoxalines and 2,3-Di(pyrazol-1-yl)quinoxalines (2-(Pyrazol-1-yl)quinoxaline류 및 2,3-Di(pyrazol-1-yl)quinoxaline류의 합성)

  • Kim, Ho-Sik;Jeong, Won-Young;Choi, Kyung-Ok;Lee, Seong-Uk;Kwag, Sam-Tag;Lee, Man-Kil
    • Journal of the Korean Chemical Society
    • /
    • v.46 no.1
    • /
    • pp.37-45
    • /
    • 2002
  • The reaction of 3,6-dichloro-2-(3,5-dimethylpyrazol-1-yl)quinoxaline(8) or 6-chloro-3-hydrazino-2-(3,5-dimethylpyrazol-1-yl)quinoxaline(9) with substituted anilines, sulfa drugs and heteroacyl chlorides gave 2-(pyrazol-1-yl)quinoxalines(10-12). The reaction of compound 9 with alkyl (ethoxymeth-ylene) cyanoacetates resulted in the intramolecular cyclization to give 2,3-di(pyrazol-1-yl)quinoxalines(13).

A Study on Riparian Habitats for Amphibians Using Habitat Suitability Model (서식지적합성 모형을 이용한 수변지역 양서류 서식지 분석)

  • Jeong, Seunggyu;Seo, Changwan;Yoon, Jaehyun;Lee, Dong Kun;Park, Jonghoon
    • Journal of Environmental Impact Assessment
    • /
    • v.24 no.2
    • /
    • pp.175-189
    • /
    • 2015
  • The objective of this study was to analyze characteristics of distribution of amphibian species and the affecting ecological factors. For the study, habitat environment factors were determined and applied to a habitat suitability model for the data collected from the Seom River in Hoengseong County and Wonju City, Gangwon Province, Korea between March 2013 to October 2013. The analyzed amphibian species were Rana nigromaculata, Hyla japonica, Rana dybowski, and Rana rugosa Temminck and Schlegel, and a logistic regression model was used with the pseudo-absence data. The result of the model analysis suggests that the major factors for Rana nigromaculata are distance to vegetation and rock and that for Hyla japonica is waterway. Rana dybowski and Rana rugosa Temminck and Schlegel have similar habitat characteristics, but the latter is shown to be dominant due to its wider habitat preference. According to the species richness model, the analyzed amphibian species are shown to have tendency to move between valleys or streams. This study quantitatively analyzed habitat environment characteristics using species distribution model, however, there is a limitation in terms of analysis on food factor and connectivity with other species. Combined with additional density or habitat analysis on birds or fish, this study can lead to more comprehensive analysis on biological environment factors.