• Korean Journal of Environmental Biology
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• v.22
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• pp.86-92
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• 2004

The marine viral density in the Gwangyang Bay was abundant about 2.0${\times}$10$^{8}$ particles ml$^{-1}$ . For each season, viral abundances were recorded from 9.0${\times}$10$^{8}$ particles ml$^{-1}$ in summer to 0.7${\times}$10$^{6}$ particles ml$^{-1}$ in winter. The spatial distributions of the viral, bacterial and phytoplankton biomass in the Gwangyang Bay were mostly highey in closed estuarine system (Station 2, 5, 10, 12, 16, 20) than open ocean system (Station 28, 38, 42, 46, 51), And the othey closed estuarine system (Station 22, 26, 32, 34) indicated higher viral abundances, lower bacterial and plankton biomass than open oceanic system. In depths of some stations, the bacterial abundances exceeded a hundred fold than viral abundances. Seasonal abundances of marine viruses and their host systems were dynamically changed, and their seasonal variations were closely correlated. In summer, viral and bacterial abundances were increased, and phytoplankton chlorophyll $\alpha$ concentrations were maintained in average values. In winter, viral and bacterial abundances were dramatically decreased, and chlorophyll a concentrations were decreased, but, immediately increased. The viral abundances were peaked in August 2001, and bacteyial abundance, in August 2001 and June 2002, while chlorophyll a concentrations were peaked in April. 2002. In total host and viral abundances, it was seemed that their pools were maintained to steady-states by viral mortality, and viral abundance maintained steady-states. In our assessments, this report is a unique research about marine viral ecology of the Gwangyang Bay in Korea.

• Journal of Environmental Policy
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• v.9 no.2
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• pp.185-205
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• 2010

Climate change vulnerability assessment based on local conditions is a prerequisite for establishment of climate change adaptation policies. While some studies have developed a methodology for vulnerability assessment at the national level using statistical data, few attempts, whether domestic or overseas, have been made to develop methods for local vulnerability assessments that are easily applicable to a single city. Accordingly, the objective of this study was to develop a conceptual framework for climate change vulnerability, and then develop a general methodology for assessment at the regional level applied to a single coastal city, Mokpo, in Jeolla province, Korea. We followed the conceptual framework of climate change vulnerability proposed by the IPCC (1996) which consists of "climate exposure," "systemic sensitivity," and "systemic adaptive capacity." "Climate exposure" was designated as sea level rises of 1, 2, 3, 4, and 5 meter(s), allowing for a simple scenario for sea level rises. Should more complex forecasts of sea level rises be required later, the methodology developed herein can be easily scaled and transferred to other projects. Mokpo was chosen as a seaside city on the southwest coast of Korea, where all cities have experienced rising sea levels. Mokpo has experienced the largest sea level increases of all, and is a region where abnormal high tide events have become a significant threat; especially subsequent to the construction of an estuary dam and breakwaters. Sensitivity to sea level rises was measured by the percentage of flooded area for each administrative region within Mokpo evaluated via simulations using GIS techniques. Population density, particularly that of senior citizens, was also factored in. Adaptive capacity was considered from both the "hardware" and "software" aspects. "Hardware" adaptive capacity was incorporated by considering the presence (or lack thereof) of breakwaters and seawalls, as well as their height. "Software" adaptive capacity was measured using a survey method. The survey questionnaire included economic status, awareness of climate change impact and adaptation, governance, and policy, and was distributed to 75 governmental officials working for Mokpo. Vulnerability to sea level rises was assessed by subtracting adaptive capacity from the sensitivity index. Application of the methodology to Mokpo indicated vulnerability was high for seven out of 20 administrative districts. The results of our methodology provides significant policy implications for the development of climate change adaptation policy as follows: 1) regions with high priority for climate change adaptation measures can be selected through a correlation diagram between vulnerabilities and records of previous flood damage, and 2) after review of existing short, mid, and long-term plans or projects in high priority areas, appropriate adaptation measures can be taken as per this study. Future studies should focus on expanding analysis of climate change exposure from sea level rises to other adverse climate related events, including heat waves, torrential rain, and drought etc.

• Journal of Nutrition and Health
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• v.15 no.4
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• pp.235-241
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• 1982

Studies were carried out on seven young, adult caucasian males to determine the short-term effects of protein(animal or plant)and calcium intakes on the excretion of urinary calcium. The subjects were studied on a self-selected diet for a period of seven days. Mean daily protein and calcium intakes were $103{\pm}31\;g$ and $1237{\pm}594mg$ respectively. Variation among subjects in the mean urinary calcium excretion per 24 hour was from $121{\pm}40$ to $258{\pm}104mg$. When the protein intake of all aubjcts was divided in to four levels : low (x=53g), medium (87g), intermediate (117g) and high(153g), The mean urinary calcium was $179{\pm}53$, $189{\pm}73$, $184{\pm}55$ and $264{\pm}84mg$, respectively. Urinary calcium increased significantly with an increase in protein intake. The calcium excretion was seriously increased with the protein intake above the intermediate level. Animal protein intake was more closely related to urinary calcium excretion than plant protein. There was a significant difference in the urinary calcium excretion when calcium intakes increased from low(x=544mg) to interne-diate levels (1232 mg). However, the difference between intermediate and high levels (1834mg) was not significant. Urinary calcium was $169{\pm}46mg$ on the low calcium diet, $196{\pm}71mg$ on the medium, and $222{\pm}21mg$ on the intermediate calcium intake, Calcium excretion was more closely related to changes in protein intake than to changes in calcium intake. Some nutritional implications can be drawn from this research. Protein intakes above the intermediate level (117g) are not recommendable. An over intake of calcium, however, may not be a serious problem for the calcium balance.

• Journal of Bio-Environment Control
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• v.3 no.2
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• pp.106-118
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• 1994

This study was conducted to analyze the effects of fluctuations in temperature, light intensity and soil temperature on the growth of red pepper seedlings in the nonheated plastic houses with various number of layers and in the open field. Relationship between the optimal environment and the growth of seedlings was discussed, and the maximum and minimum outdoor temperatures in Kwangju area from 1941 to 1985 were analyzed. The results obtained were as follows; 1. The minimum temperature in tunnel with quadruple coverings of P. E. film from December 20 to February 25 was decreased to 5$^{\circ}C$ mostly, where the exposure to chilling temperature could not be avoided during this period. The maximum temperature was increased to 33$^{\circ}C$ mostly and 42$^{\circ}C$ in peak, where some ventilation was needed. 2. The diurnal differences of inside temperature, increasing with number of layers, were 16 to 38$^{\circ}C$, while those of outside temperature were 5 to 1$0^{\circ}C$. 3. The cold injury in the quadruple coverings during winter occurred all the times below 12$^{\circ}C$ and as many as 200 times over 3$0^{\circ}C$, while effectiveness of thermal insulation in the multilayered nonheating plastic houses were clearly proved. 4. The inside light intensity was markedly reduced with the increment of layers and the minimum light intensity fallen down below the light compensation point for the growth of red pepper plants regardless of the number of layers. 5. Until 10 a. m., the temperature in the daytime during December 20 to mid - February showed below 10 to 12$^{\circ}C$ which was the limiting temperature for the growth of red pepper seedlings. After 4 p. m., the light intensity was sharply reduced despite of the air temperature kept over 12$^{\circ}C$. Therefore, limiting factors for the growth of red pepper seedlings were the temperature before 10 a. m. and the light intensity after 4 p. m. 6. The minimum soil temperature in quadruple coverings showed around 1$0^{\circ}C$ where the physiological damage for red pepper seedlings might be occurred. 7. The minimum outdoor temperatures from 1941 to 1985 was -19.4$^{\circ}C$, observed in the 5th January.

• Pediatric Infection and Vaccine
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• v.18 no.1
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• pp.40-47
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• 2011

Purpose : Norovirus infection, a common cause of community-acquired gastroenteritis, can also lead to severe illness in immunocompromised patients. We investigated clinical manifestations of norovirus infection in pediatric cancer patients. Methods : Stool specimens were collected from pediatric patients with gastrointestinal symptoms between November 2008 and September 2009 at Samsung Medical Center, Seoul, Korea. Norovirus infection was identified by reverse-transcription polymerase chain reaction (RT-PCR). A retrospective chart review was performed in pediatric cancer patients who were diagnosed with norovirus infection. Results : Ten patients were diagnosed with norovirus infection by RT-PCR in stool samples. The median age was 0.83 years (range 0.25-5.5 years) and the male to female ratio was 1.5:1 (6 males and 4 females). Underlying diseases were hematologic malignancies (4/10, 40%), neuroblastoma (4/10, 40%), and brain tumors (2/10, 20%). Three patients were infected before hematopoietic cell transplantation (HCT) and four patients after HCT. All patients had diarrhea (10/10, 100%), with a median frequency of diarrhea of 8.5 times/day (range 4-22 times/day). Median virus shedding duration was 72.5 days (range 19-299 days). Four patients with pneumatosis intestinalis were conservatively treated with bowel rest and total parenteral nutrition. One patient with severe diarrhea and bloody stool had concomitant chronic gut graft-versus-host disease (GVHD). Norovirus infection-related mortality was not observed. Conclusion : Norovirus infection can cause significant clinical manifestations with prolonged viral shedding in immunocompromised patients. Norovirus should be considered in pediatric cancer patients with severe gastrointestinal symptoms.

• Childhood Kidney Diseases
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• v.13 no.2
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• pp.146-152
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• 2009

Purpose : We performed this study to evaluate the incidence and clinical significance of antiphospholipid antibodies (aPL Ab) in Korean children with Henoch-$Sch{\ddot{o}}nlein$ purpura (HSP). Methods : The medical records of 62 patients (31 boys and 31 girls) aged $46.0{\pm}3.1$ (1-16) years with a clinical diagnosis of HSP based on the EULAR/PReS criteria were reviewed retrospectively. From the years 2007 to 2009, the sera from children with acute HSP were tested for aPL Ab such as LA, anti-cardiolipin antibody and anti-${\beta}_2$ glycoprotein I antibody. Results : LA was positive in 18 (29%) of the 62 patients with HSP and We divided the patients into the two groups LA positive group (N=18) and LA negative group (N=44). There were no significant differences between the two groups with regard to abdominal pain, arthralgia and renal involvement, but LA positive group had significantly higher C-reactive protein ($4.3{\pm}7.2$ mg/dL vs. $1.3{\pm}1.8$ mg/dL, P=0.035), erythrocyte sedimentation rate ($37.5{\pm}26.2$ mm/hr vs. $25.1{\pm}22.6$ mm/hr, P= 0.039), IgM ($148.1{\pm}48.4$ mg/dL vs. $114.9{\pm}41.5$ mg/dL, P=0.024), C3 ($143.1{\pm}21.9$ mg/dL vs. $129.7{\pm}24.5$ mg/dL, P=0.048) and C4 levels ($30.9{\pm}6.3$ mg/dL vs. $24.9{\pm}7.8$ mg/dL, P=0.002) compared with LA negative group. Conclusion : We found that the incidence of positive aPL Ab tests was relatively higher in Korean children with HSP and the presence of aPL Ab was associated with acute inflammatory process of HSP. These results suggest that the aPL Ab are involved in the pathogenesis of HSP in children.

• Korean Journal of Psychosomatic Medicine
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• v.13 no.2
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• pp.75-84
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• 2005

Objectives : This study was conducted to look over the current status of psychiatric consultation in a general hospital. Methods : We analyzed 664 medical records : 317 in 2002 and 347 in 1997, and compared the records of 1997 and 2002. Results 1) The average age of the patients increased from 45.9 years(1997) to 53.2 years of age (2002). Dividing the referred patients into 3 age-brackets as below 40, between 40 and 60, and above 60, the number of patients in the age group above 60 was significantly increased, more prominently in women. 2) Overall consultation rate was 2.29% in 2002 and 2.2% in 1997 .44.2% and 57.1% of the whole referrals were from the department of internal medicine in each year, and the department of rehabilitation medicine was leading in consultation rate in both years. 3) 'Mood disorders' and 'Substance related disorders' were the most frequent diagnoses in 2002 and 1997 respectively. 4) Use of psychotropic drugs was the most frequent recommendations of psychiatric consultation, in both years, and the most frequently prescribed drugs were anti-anxiety drugs in both years. The use of SSRI and atypical anti-psychotics were increased, while the use of typical anti-psychotics was decreased significantly in 2002. Conclusion : In 2002, compared with 1997, the average age of the patients was increased, and the consultation of the patients with the diagnosis of 'mood disorders' and 'cognitive disorders' was done more frequently than in 1997. The recommendation to use psychotropic drugs was well accepted, but the concern to diagnostic procedure was relatively low.

• Korean Journal of Psychosomatic Medicine
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• v.9 no.1
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• pp.28-36
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• 2001

Objectives : This study was undertaken to identify the clinical and psychological characteristics in patients of mental disability assessment following traumatic brain injury who had the finding with or without abnormal brain imaging study. Methods : A consecutive series of 59 patients were assessed in hospital from January 1994 to December 1998. Patients were divided into 2 groups based on normal or abnormal brain imaging and the two groups were compared in demographic characteristics, psychiatric symptoms, type of head injury, clinical psychological findings. There were 27 patients with abnormal findings and 32 with normal findings in brain imaging study. Results : Abnormal finding group in brain imaging study had significantly higher incidence of psychosis, decreased memory, decreased appetite, increased nihilistic idea, and intracranial hemorrhage. Also, abnormal finding group showed significantly lower level of performance on the block design subtest of K-WAIS and had significantly lower scores on F, hypochodriasis, depression, hysteria, psychopathic deviate, psychasthenia and schizophrenia subscale of the MMPI. Conclusion : The findings suggest that the patients undergone brain surgery due to intracranial hemorrage at that time of brain injury may have higher frequency of abnormal findings in brain imaging study, complain more cognitive and affective symptoms, and have lower the abstract concept formation and perceptual organization abilities.

• Korean Journal of Psychosomatic Medicine
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• v.25 no.1
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• pp.73-85
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• 2017

Objectives : In this study I made investigations how 'strange hunger' and 'compulsive overeating' threatening the ego could be resolved and healed. And I aim to present a healing model of psychotherapy and analysis as one of methods of treatment for 'eating disorder'. Methods : The analysands of this study were outpatients who visited the department of psychiatry of Yong-In Mental Hospital from March 2008 to February 2017 with 'hunger' and 'compulsive overeating' as their chief complaints. This study is based on the detailed records of the process of analysis including dreams and visions. Results : 1) Throughout the process of analysis that explore both consciousness and unconsciousness(dream, vision), hunger and compulsive overeating is improved and healed in all analysands. 2) The Imago of 'Snake' appeared in dreams and visions of all analysands. 3) By suffering impulse rather than acting it out, impulse transformes itself into 'Imago'. As impulse transforms into 'Imago' and reveals the 'meaning' of it, ego-threatening power of impulse weakens and mood is calmed. And as a result, synthesis of consciousness and unconsciousness and creative transformation of personality can be possible. Conclusions : In some people, 'hunger' and 'compulsive overeating' are 'creative impulses' that aim 'Self-realization' which can be fruited as creative transformation of personality and as creative transformation in the relation with the world. 'Creative impulses', which often can be experienced as instinctive impulse or emotional suffering unless ego realizes the meaning, reveal the meaning in dreams or visions through 'Imago' and 'Symbol'.

• Korean Journal of Psychosomatic Medicine
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• v.26 no.1
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• pp.51-58
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• 2018

Objectives : We aimed to investigate the discontinuation rate and reasons of doxepin base prescription pattern in insomnia outpatients of psychiatry department of a university hospital. Methods : 534 patients prescribed doxepin were screened. 201 patients were included and reviewed for their medical records retrospectively. The discontinuation rate and reasons of doxepin after 2 months of prescription were investigated. Patients were divided into three groups according to the prescription patterns. The initial group, prescribed doxepin as the first hypnotic, the add-on group, prescribed doxepin while maintaining existing hypnotics, and the switching group, prescribed doxepin after discontinuation of existing hypnotics. Results : The discontinuation rate after 2 months of prescription of doxepin was 56.2%. There were significant differences in the discontinuation rate among three groups. The initial group had the highest while the add-on group had the lowest (p=0.018). In reasons for discontinuation of doxepin among three groups, lack of efficacy (p<0.001) and adverse events (p<0.001) were significantly higher in the add-on group. In the initial group, patient's refusal (p=0.022) and unknown or loss to follow up (p<0.001) were significantly higher. Conclusions : The results of this study suggested that add-on is superior than switching method and gradual reduction of existing hypnotics is necessary to maintain doxepin treatment and prevent adverse events. Additional large scale prospective studies are needed to evaluate various factors and risks of discontinuation of doxepin.