• Title/Summary/Keyword: 플라보노이드

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Biological Activity of Methanolic Extract from Ganoderma lucidum, Momordica charantia, Fagopyrum tataricum, and Their Mixtures (영지버섯, 여주, 쓴메밀 및 혼합 시료의 메탄올 추출물의 생리활성)

  • Cha, Jae-Young;Jin, Jong-Sung;Cho, Young-Su
    • Journal of Life Science
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    • v.21 no.7
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    • pp.1016-1024
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    • 2011
  • The concentrations of bioactive material (polyphenolics and flavonoids) and the biological activities of antioxidative (DPPH [${\alpha},{\alpha}'$-diphenyl-${\beta}$-picrylhydrazyl] free radical scavenging activity, peroxidation of rat liver microsome, and Fe/Cu reducing power), ${\alpha}$-glucosidase inhibition, tyrosinase inhibition, and fibrinolytic activity were tested by in vitro experimental models using 70% methanolic extract from Ganoderma lucidum, Momordica charantia, Fagopyrum tataricum and their mixtures. The highest yield and the concentrations of polyphenolics and flavonoids were shown in the mixture extract. Mixture extract was shown to have the highest activities of ${\alpha}$-glucosidase inhibition and tyrosinase inhibition, fibrinolytic, DPPH free radical scavenging, and Fe/Cu reducing power in a concentration-dependent manner. From these results, mixture methanol extract was shown to have the most potent bioactive properties and to contain large amounts of biological materials such as polyphenolics and flavonoids. This mixture could be a good dietary supplement material candidate, such as for antidiabetic functional foods.

Ingredient Contents of Nipa Palm(Nypa fruticans Wurmb.) according to Different Extraction Methods (추출방법에 따른 니파팜의 성분 함량)

  • Kim, Myong-Ki
    • Journal of Convergence for Information Technology
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    • v.11 no.5
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    • pp.104-110
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    • 2021
  • This study was conducted to confirm the change in the contents of the ingredients according to the extraction method of nipa palm. The contents were analyzed by extraction according to the ethanol ratio, extraction time, and extraction temperature. The contents of polyphenols and flavonoids according to the ratio of the extraction solvent were the highest at 36.91 and 27.62 mg/g, respectively, when extracted with 50% ethanol. Polyphenols and flavonoids according to extraction temperature and extraction time showed the highest content of 40.83 and 37.63 mg/g, respectively, when extracted for 6 hours at 60℃. The contents of the major component of nipa palm according to the ethanol ratio were 2.08 mg/g in 70% ethanol for 5-O-caffeoylshikimic acid, 0.10 mg/g for 4-hydroxybenzoic acid in 30% ethanol, and 0.12 mg/g for 3,4- hydroxybenzoic acid in 50% ethanol. It is expected that it can be used as basic research data when developing natural materials such as food and cosmetics through the change in the contents of the ingredients contained in nipa palm according to the extraction methods.

A convergence study of antibacterial effect of solanum nigrum extract on candida albicans (까마중 추출물의 Candida albicans에 대한 항균효과에 대한 융합적 연구)

  • Choi, Yu-Ri;Kang, Min-Kyung
    • Journal of the Korea Convergence Society
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    • v.9 no.12
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    • pp.69-74
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    • 2018
  • The purpose of this study was to antibacterial effect of solanum nigrum extra in candida albicans. In this study, the antibacterial effects of 70% methanol extract and solanum nigraum were investigated. The content of flavonoids and polyphenol contents in solanum nigrum extraction. The antimicrobial activity was determined by spectrophotometric growth inhibition assay(optical density) and colony forming untis (CFU) for the candida albicans. Total contents were flavonoids and polyphenols of solanum nigrum, the result was $8.23{\pm}0.13mg/g$ and $14.97{\pm}1.58mg/g$, respectively. The CFU results showed lower CFU counts in the experimental groups compared to the control group. And the result of the bacterial viability was decreased in the experimental group. Therefore the extracts of solanum nigrum were found to have antimicrobial activity in candida albicans. From the these results, solanum nigrum extracts have a possibility to be a candidate for natural antibacterial components in dental products.