• Journal of The Korean Society of Integrative Medicine
• /
• v.11 no.1
• /
• pp.63-70
• /
• 2023

Purpose : Excessive alcohol causes damage to skeletal muscles, leading to the development of a specific disease entity called alcoholic myopathy. Chronic inflammation is related as an underlying mechanism for the loss of muscle mass induced by alcohol. Pro-inflammatory cytokines such as TNF-α (tumor necrosis factor-α) and IL-6 (interleukin-6) play a role in this process. The acupuncture point Feng Shi (GB 31) is located on the midline of the lateral aspect of the thigh, above the transverse popliteal crease. This acupoint is used for the treatment of weakness, atrophy, numbness, and post-stroke symptoms of lower limbs. The purpose of this study was to investigate the effect of Feng Shi stimulation on muscle atrophy caused by chronic alcohol administration. Method : Young male Sprague-Dawley rats were randomly divided into three groups of eight each: Normal, Control, and GB31. The rats in the Control and GB31 groups were orally given 25 % ethanol (5 ㎖/kg, body weight) daily for 4 weeks. The Normal group was similarly administered saline. The acupressure at Feng Shi was treated to rats in the GB31 group. After 4 weeks, the body weight, muscle weight and cross-sectional area of gastrocnemius were assessed and the histological changes in gastrocnemius muscle fiber were observed by hematoxylin and eosin staining. Moreover, TNF-α and IL-6 expressions were immunohistochemistrically evaluated. Results : Acupressure stimulation at Feng Shi had a protective effect on the weight reduction of the gastrocnemius muscle caused by alcohol intake, and had an effect of suppressing anatomical change in muscle fiber and decreasing the average cross-sectional area. Also, the immunoreactivities of TNF-α and IL-6 in the GB31 group were decreased. Conclusion : These results suggest that acupressure at Feng Shi has protective effects on chronic alcohol-induced muscle atrophy by inhibiting pre-inflammatory proteins such as TNF-α and IL-6.

• (The)Study of the Eastern Classic
• /
• no.37
• /
• pp.249-278
• /
• 2009

Zhu-zi(朱子) represented the study of The Book of Odes in Song dynasty and Dai-zhen(戴震) was The Book of Odes researcher representing Wan-pai(a kind of party) in Qing dynasty. Especially Dai-zhen took critical position of Zhu-xi. Comparing Zhu-zi with Dai-zhen in the aspect of The Book of Odes interpretation, this thesis intends to review the difference and the reason of both interpretations. Especially this thesis compares Zhu-zi's interpretation with Dai-zhen's about thirty poems Zhu-zi considered filthy poetry, investigating the differences of their interpretation. Regarding the poetry Zhu-zi considered filthy as refined satire, Dai-zhen had a negative position about Zhu-zi's theory of filthy poetry. As Zhu-zi interpreted the poetry in the first person on the literary view in the time when he interpreted the lyrics in the Feng-shi, he regarded the purpose and the usefulness of poetry as feeling of words. But as Dai-zhen interpreted the poetry in the third person under a Confucian classic view, he regarded the purpose and the usefulness of poetry as refined satire. In brief, that is to say that Zhu-zi made literary interpretations of feeling of words but Dai-zhen made Confucian classic interpretations of 'Si-wu-xie'(思無邪). These two men's differences about interpretation of The Book of Odes have much importance on the historical aspects of The Book of Odes. So to speak, Dai-zhen had bibliographical approach and described the meaning of poetry objectively, following Mao-shi(毛詩) theory about the interpretation of meaning of poetry, criticizing Zhu-zi's literarary view. Dai-zhen's interpretation of The Book of Odes mentioned Above was made from long vital power of Mao-shi theory and a Confucian classic method. Considering the historical stream of Zhu-zi and Dai-zhen's interpreting The Book of Odes, The Book of Odes will be interpreted and analyzed from the various views in the future.

• Journal of Acupuncture Research
• /
• v.22 no.1
• /
• pp.109-115
• /
• 2005

Objective : The purpose of this case is to report the improvement after treatment about a patient with meralgia paresthetica. Methods : We treated the patient with acupuncture therapy and Herbal medication from 11th October 2004 to 15th October 2004 by evaluating femoral function with VAS score and R.O.M of femur joint. Results : After 5 times of treatment, this patient achieved excellent outcome following the technique, showing that clinical symptom as like heating sense, edema and pain was disappeared, VAS changed from 10 to 1 and there was no limitation of ROM of femur. Conclusions : Meralgia paresthetica is a symptom complex that includes numbness, paresthesias, and pain in the anterolateral thigh, which may result from either an entrapment neuropathy or a neuroma of the lateral femoral cutaneous nerve(LFCN). Oriental medical treatment for meralgia paresthetica resulted in satisfactory results by diminishing the symptoms progressively during the five days of treatment. Differential diagnosis was based on careful physical examination. More research of meralgia paresthetica is needed.

• Tuberculosis and Respiratory Diseases
• /
• v.51 no.5
• /
• pp.416-425
• /
• 2001

Background : The incidence of drug-resistant tuberculosis has recently decreased in Korea. However, it is still one of the major obstacles in treating pulmonary tuberculosis. This study was performed to determine the prevalence and clinical characteristics associated with drug-resistance in pulmonary tuberculosis at the tertiary referral hospital in Pusan, Korea. Methods : The medical records of 138 patients, who had been diagnosed as active pulmonary tuberculosis were retrospectively reviewed, and results of drug susceptibility from May 1997 to June 2000. The relationships among those with a history of previous tuberculosis treatment, the extent of lung involvement, the presence of cavities on the initial chest X-ray films and patterns of drug resistance were analyzed. Results : The total number of patients who had drug resistance to at least one drug was 55(39.9%). Among them 34(24.6%) had resistance to isoniazid(INH) and rifampin(RFP). There was drug resistance in 20(22%) of 91 patients without previous tuberculosis therapy, and among them 9(9.9%) were multi-drug resistant. Thirty-two(74.5%) out of 47 patients with previous therapy were drug-resistant and 25(53.2%) were multidrug resistant. For all 138 patients, resistance to INH was the most common(34.1%), followed by RFP(26.1%) and ethambutol(EMB)(14.5%). Drug resistance to INH, RFP, PZA and streptomycin(SM) were independently associated with a history of previous treatment(odds ratio; 9.43, 9.09, 8.93 and 21.6 respectively, p<0.01). The extent of lung involvement on the chest films was significantly associated with the drug resistance to INH and RFP(odds ratio; 2.12 and 2.40 respectively, p<0.01). The prevalence of drug resistance to RFP, INH and RFP was significantly more common in patients with a cavitary lesion on the chest films by multivariate analysis(odds ratio; 4.17 and 4.81 respectively, p<0.05). Conclusion : This study revealed that patients with a prior treatment history for pulmonary tuberculosis, and the presence of a cavitary lesion on chest films had a higher prevalence of anti-tuberculosis drug resistance. A very careful clinical and microbiological examination is needed for patients with such characteristics.